This catalogue, which integrates nearly 35,000 records of benthic marine algae from the Indian Ocean into a taxonomic classification comprising 3,355 specific and infraspecific taxa in 629 genera, will greatly facilitate future work in this region. The bibliography of 4,000 references is the largest list of phycological literature ever published. The extensive taxonomic and nomenclatural notes are of paramount importance.
With organizations and individuals increasingly dependent on the Web, the need for competent, well-trained Web developers and maintainers is growing. Helping readers master Web development, Dynamic Web Programming and HTML5 covers specific Web programming languages, APIs, and coding techniques and provides an in-depth understanding of the underlying concepts, theory, and principles. The author leads readers through page structuring, page layout/styling, user input processing, dynamic user interfaces, database-driven websites, and mobile website development. After an overview of the Web and Internet, the book focuses on the new HTML5 and its associated open Web platform standards. It covers the HTML5 markup language and DOM, new elements for structuring Web documents and forms, CSS3, and important JavaScript APIs associated with HTML5. Moving on to dynamic page generation and server-side programming with PHP, the text discusses page templates, form processing, session control, user login, database access, and server-side HTTP requests. It also explores more advanced topics such as XML and PHP/MySQL. Suitable for a one- or two-semester course at the advanced undergraduate or beginning graduate level, this comprehensive and up-to-date guide helps readers learn modern Web technologies and their practical applications. Numerous examples illustrate how the programming techniques and other elements work together to achieve practical goals. Online Resource Encouraging hands-on practice, the book’s companion website at http://dwp.sofpower.com helps readers gain experience with the technologies and techniques involved in building good sites. Maintained by the author, the site offers: Live examples organized by chapter and cross-referenced in the text Programs from the text bundled in a downloadable code package Searchable index and appendices Ample resource listings and information updates
The Geography of the World Economy provides an in-depth and stimulating introduction to the 'globalization' of the world economy. The book offers a consideration of local, regional, national and global economic development over the long historical term. The theory and practice of economic and political geography provide a basis for understanding the interactions within and among the developed and developing countries of the world. Illustrated in colour throughout, this new edition has been completely reworked and updated to take account of the substantial changes in the world economy, and includes a new chapter on services. It is ideal for upper level university undergraduates and for post-graduates in a variety of specializations including geography, economics, political science, international relations and global studies.
Revised and updated for its Seventh Edition, this highly acclaimed volume is a complete, current, and practical guide to the diagnosis and treatment of allergic disorders. This comprehensive yet concise reference will remain the first choice for residents and practitioners who need guidance to identify an allergy, confirm a diagnosis, or find effective therapies. It will also be an excellent aid for board review. This edition includes discussions of clinical trials in asthma and significant updates on drug allergy, imaging, occupational allergy, and immune deficiency evaluation. A Companion Website will include the fully searchable text and additional illustrations and tables.
External fixation has proven a valuable tool in the effort to correct deformities, improve healing of fractures, and improve outcomes of orthopedic surgery. This expertly constructed reference, External Fixators of the Foot and Ankle, explores the ways in which external fixators are used to reduce tissue damage, reduce strain on nerves and vasculature, and improve healing in the surgical treatment of foot and ankle deformities and injuries. Authoritative perspectives from leading orthopedic and podiatric surgeons help to build an understanding and strengthen your technique. The multidisciplinary team approach in treating complex trauma, reconstructive, or diabetic patients is emphasized throughout this textbook. Detailed coverage of the tools of external fixation describes the roles, applications, and limitations of the various rings, rods, wires, pins, and designs used in external fixation. How-to, step-by-step instruction addresses a range of fixation procedures, helping readers understand the relevant anatomy and avoid potential complications. Abundant illustrations highlight the text, providing a surgeon’s eye view of a range of commonly performed procedures.
The most comprehensive, multi-disciplinary text in the field, Cummings Otolaryngology: Head and Neck Surgery, 7th Edition, provides detailed, practical answers and easily accessible clinical content on the complex issues that arise for otolaryngologists at all levels, across all subspecialties. This award-winning text is a one-stop reference for all stages of your career—from residency and board certification through the challenges faced in daily clinical practice. Updated content, new otology editor Dr. Howard W. Francis, and new chapters and videos ensure that this 7th Edition remains the definitive reference in today's otolaryngology. - Brings you up to date with the latest minimally invasive procedures, recent changes in rhinology, and new techniques and technologies that are shaping patient outcomes. - Contains 12 new chapters, including Chronic Rhinosinusitis, Facial Pain, Geriatric Otology, Middle Ear Endoscopic Surgery, Pediatric Speech Disorders, Pediatric Cochlear Implantation, Tongue-Ties and Lip Ties, Laryngotracheal Clefts, and more. - Covers recent advances and new approaches such as the Draf III procedure for CRS affecting the frontal recess, endoscopic vidian and posterior nasal neurectomy for non-allergic rhinitis, and endoscopic approaches for sinonasal and orbital tumors, both extra- and intraconal. - Provides access to 70 key indicator (Accreditation Council for Graduate Medical Education Key Indicator Procedures), and surgical videos – an increase of 43% over the previous edition. - Offers outstanding visual support with 4,000 high-quality images and hundreds of quick-reference tables and boxes. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Woodhead and Wicker's new text will be the foremost reference source for all perioperative practitioners. The content mirrors the dynamics of modern perioperative practice by focusing on surgical interventions in all the environments in which it is currently practised, including A&E departments, general practice clinics, intensive care units, and at the site of serious accidents. Theatre practice is becoming increasingly specialist; this book does not attempt to to reflect the needs of all specialties, but instead concentrates on the principles of practice, applicable to any setting and any specialty. It has a very practical focus - it aims to be the book that nurses and ODPs reach for in order to answer their practical questions - but is not be procedure-driven. Instead, it sets out the principles of perioperative practice, from which practitioners will be able to develop their own practice techniques. Reflects principles of practice, applicable to any perioperative environment Strong practical focus Edited by two of the biggest 'names' in the international perioperative nursing sphere, with contributions from other well-known and authoritative sources Excellent opportunities to develop links with the National Association of Theatre Nurses and the European Operating Room Association The team of contributors are experienced practitioners working directly with perioperative patients or in perioperative education An original model for ethical practice is proposed: the Reid model is the first such ethical model to be proposed for the perioperative environment Includes one of the only chapters in any perioperative book which specifically focuses on the care of the elderly. The research chapter encourages the use of evidence based practice and the development of perioperative research The unique chapter on care of the mentally ill will support practitioners who are not qualified in psychiatry to care for mentally ill patients. This is an area where there is a great information deficit Key points listed for each chapter Sections have been completely revised from previous edition - key subject areas now stand-alone chapters rather than sections within much larger chapters - creates ease of access for user Change of editorship Recognises the diversity of perioperative environments much more explicitly than previous edition
Orthopaedics and orthopaedic trauma are highly complex subjects that can prove difficult to quantify, but accurate measurement is required for setting standards of care and for assessing the severity of an injury. This book will help the reader assess outcome instruments, and provides many references to sources of instruments and techniques to use. It aims to assist the reader in making an informed selection from the different scoring systems available. Outcome Measures in Orthopaedics and Orthopaedic Trauma is a combined and fully revised new edition of the highly regarded Outcome Measures in Orthopaedics and Outcome Measures in Trauma, the first books devoted to the topic of outcome measures for orthopaedic and trauma surgeons and researchers.
Based on the Diagnostic and Statistical Manual for Primary Care: Child and Adolescent Version (DSM-PC), this state-of-the-art reference expertly guides you through normal and abnormal development and behavior for all pediatric age groups. See how neurobiological, environmental, and human relationship factors all contribute to developmental and behavioral disorders and know how to best diagnose and treat each patient you see. Accurately identify developmental and behavioral problems using the Diagnostic and Statistical Manual for Primary Care criteria, and evidence-based guidelines. Gain a clear understanding of the "normal" boundaries and variations within specific disorders. Make informed therapeutic decisions with the integration of basic science and practical information and recommendations from the Society of Developmental and Behavioral Pediatrics and the American Academy of Pediatrics. Avoid legal and ethical implications by consulting the Law, Policy, and Ethics chapter.
Renal sonography forms a basic part of routine diagnostic strategy. This textbook summarizes eighteen years of experience in diagnostic ultrasound. We want it to serve as a guide to both imagers and mere consumers of information. That is why we shall emphasize practical advice and diagnostic pitfalls; it is also why we shall often deal with the relations of sonography with other diagnostic procedures, which it may complement or replace, precede or follow, the purpose being to achieve efficiency at low cost. We shall limit our subject matter to the kidney itself and the neighboring retroperitoneal compartments, dealing only briefly with the lower urinary tract, which requires specialized procedures. We devoted considerable space to renal sonography in our book Clinical Atlas of Ultrasonic Radiography, published in 1973. Since then, nothing has changed and everything has changed. Nothing, because even then the differential diagnosis between a solid and a cystic mass, the etiologic diagnosis of a nonsecreting kidney, and the positive diagnosis of a traumatic juxtarenal hematoma were quite reliable, making possible drastic reductions in the indications for instrumental roentgenologic examinations. Everything, be cause improved resolution and grey scale imaging (already partially achieved in 1973, thanks to real time) have profoundly refined both anatomic and pathologic ultrasonic studies. And now high resolution real time imaging has revolutionized renal examination techniques, whereas Doppler is entering routine ultrasonic diagnosis.
An up-to-date overview of acute and chronic pancreatitis. The two authors with special interests in this field deal with the aetiology, pathophysiology, and clinical features of these diseases, as well as complications, treatment strategies, and prognostic factors. Two chapters on congenital abnormalities and hereditary pancreatic diseases round off this book. Intelligently-structured for everyday practice, this can also be used as an actual reference book. For gastroenterologists in clinic and practice.
This book explores the hopeful possibility that emerging geographies of postsecularity are able to contribute significantly to the understanding of how common life may be shared, and how caring for the common goods of social justice, well-being, equality, solidarity and respect for difference may be imagined and practiced. Drawing on recent geographic theory to recalibrate ideas of the postsecular public sphere, the authors develop the case for postsecularity as a condition of being that is characterised by practices of receptive generosity, rapprochement between religious and secular ethics, and a hopeful re-enchantment and re-shaping of desire towards common life. The authors highlight the contested formation of ethical subjectivity under neoliberalism and the emergence of postsecularity within this process as an ethically-attuned politics which changes relations between religion and secularity and animates novel, hopeful imaginations, subjectivities, and praxes as alternatives to neoliberal norms. The spaces and subjectivities of emergent postsecularity are examined through a series of innovative case studies, including food banks, drug and alcohol treatment, refugee humanitarian activism in Calais, homeless participatory art projects, community responses to the Christchurch earthquakes in New Zealand, amongst others. The book also traces the global conditions for postsecularity beyond the Western and predominantly Christian-secular nexus of engagement. This is a valuable resource for students in several academic disciplines, including geography, sociology, politics, religious studies, international development and anthropology. It will be of great interest to secular and faith-based practitioners working in religion, spirituality, politics or more widely in public policy, urban planning and community development.
This book reflects the different efforts made by veterinary and medical doctors for better knowledge of the disease. It shows how much we depends on each other to understand better the clinical features, pathogenesis, and epidemiology of campylobacter infections and other diseases.
During the past two decades, the world scientific community has witnessed major achievements in our understanding of the pathogenesis of HIV infection of the nervous system and HIV-Associated Dementia (HAD). Despite these giant gains, nervous system involvement during AIDS remains a relentlessly progressive disease with a deadly fate in many cases. This book on NeuroAIDS provides a unique resource for both general neurologists as well as basic neuroscientists with profound interests for research on NeuroAIDS. This book has special emphasis on the mechanisms of disease development and progression of HIV-infected patients with NeuroAIDS. The contributors have provided the readers with comprehensive reviews on clinical manifestations of HAD, mechanisms of HIV entry into the central nervous system, the role of cytokines and chemokines in pathogenesis of NeuroAIDS, drug abuse and NeuroAIDS, virus load in HAD, allostasis in HIV and AIDS, stroke in AIDS patients, and neuroimaging of HIV infection of the central nervous system. In addition, there are chapters on Varicella Zoster virus infection of HIV-seropositive and AIDS patients, as well as the molecular basis for opioids and AIDS virus interactions.
The use of cannabinoid-based medicines (CBM), and cannabis in particular, has risen steadily among cancer and palliative care patients over the last few years. This textbook aims to address the multiple challenges facing healthcare providers regarding the use of CBM in this vulnerable patient population. It provides insight into the latest preclinical and clinical data and offers a practical approach on the use of CBM in a rapidly evolving landscape. It answers questions regarding the prescribing process and elucidates controversies regarding cannabis’ disease-modifying effects. The first chapters will review basic concepts of the endocannabinoid system and pharmacology of CBM, while focusing more specifically on the unique characteristics of two main cannabinoids: THC and CBD. Indicating which benefits can be expected from using either or both of these compounds, the book then addresses issues of drug-drug interactions and other challenges involved in prescribing CBM to frail patients with polypharmacy and multiple comorbidities. Comparing available products, both approved and non-approved by the FDA, the book discusses regional challenges for accessing reliably tested and labelled products in the context of standardization efforts. After carefully determining objectives and addressing patient expectations, further chapters will examine the different clinical settings in which CBM may be useful in cancer care and explore symptom management, including cancer pain, anxiety, nausea, and insomnia among others. The possible benefits of cannabis psychoactivity will also be discussed, including harm reduction strategies for patients who wish to explore these effects. Cannabis and Cannabinoid-Based Medicines in Cancer Care: A Comprehensive Guide to Medical Management serves as a comprehensive text for oncologists, palliative care specialists, general practitioners, and nurse practitioners working with cancer patients or in palliative care settings.
In our post-9/11 world, the laws of aviation are under intense scrutiny. From torts law and victim compensation to passenger screening, pilots with guns, and international aviation agreements, the practice of aviation law is burgeoning. The book, AVIATION LAWS: Cases, Laws, and Related Sources, fills a gap in legal literature. It is directed to both practicing lawyers and to law students. The book introduces all the major areas of air law: International air law regime, crimes involving aircraft, economic regulation of domestic and international air carriage, litigation management, domestic and international liability regimes, governmental immunity from liability, airport law, airline travel restrictions, airport law, insurance, NTSB accident investigation, aircraft financing, FAA regulation of air safety, and airline labor relations. These subjects are presented not only in explanatory text, but also in cases and related source materials. The most important texts are annexed. The authors, Professors Larsen and Gillick, have regularly taught the course in Air Law at Georgetown University Law Center for more than 30 years. They have long time hands-on experience at the Department of Transportation and in private practice. Professor Sweeney, John D. Calamari Distinguished Professor of Law, has taught the course at Fordham University Law School for 30 years. He also has extensive transportation practice background. Classroom adoption: $85/copy for 10 or more copies. Student Edition : 1–57105–340-9, $95/copy Published under the Transnational Publishers imprint.
The highly anticipated update of the complete textbook of dermatologic science and practice focusing on the care of patients with moderately to heavily pigmented skin – 21 new chapters with more than 900 photographs! Dermatology for Skin of Color, Second Edition is a comprehensive reference that thoroughly details every aspect of dermatologic science as it applies to skin of color – from the development of the skin to the biology of hair and nails. All commonly encountered dermatologic problems of Africans, Asians, Arabs, Native Americans, and other peoples are covered, as are other diseases with significant skin manifestations. This second edition is significantly expanded with 21 new chapters covering dermatology for geriatric, adolescent, and pregnant patients, as well as depigmenting agents, viral infections, cutaneous manifestation of internal malignancy, neurofibromatosis, tuberous sclerosis, photoaging, photosensivity, laser treatment for skin-tightening, toxins and fillers, cosmetic practices in Mexico, effects of tattooing and piercing, sickle cell disease, drug eruptions, and the biology of oral mucosa. It also features many more clinical pictures and improved organization. Extensively illustrated with more than 900 full-color photos, Dermatology for Skin of Color provides comprehensive coverage of medical, surgical, and cosmetic treatment options, pediatric dermatology, differences between skin of color and Caucasian skin, differences between ethnic groups with skin of color, and important basic science information on the structure and function of skin of color. In addition, folk remedies and over-the-counter treatments specifically targeting this population are covered.
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. These phages played a unique role in early studies of molecular biology, the genetic code, translation, replication, suppression of mutations. Special attention is devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery, evolutionary and environmental studies. Included is an overview of the generation of novel vaccines, gene therapy vectors, drug delivery, and diagnostic tools exploring the role of RNA phage-derived products in the revolutionary progress of the protein tethering and bioimaging protocols. Key Features Presents the first full guide to single-stranded RNA phages Reviews the history of molecular biology summarizing the role RNA phages in the development of the life sciences Demonstrates how RNA phage-derived products have resulted in nanotechnological applications Presents an up-to-date account of the role played by RNA phages in evolutionary and environmental studies
A must have resource for clinicians and investigators interested in pulmonary embolism and deep venous thrombosis Highly illustrated with numerous tables and graphs alongside clear concise text Includes chapters addressing pulmonary embolism (PE) and deep venous thrombosis (DVT) in relation to diseases and disorders such as; chronic heart failure, cancer, diabetes, stroke, chronic obstructive pulmonary disease (COPD) and many more Discusses the role the different tools offered in imaging for PE, including echocardiography, multidetector computed tomography (CT), single photon emission computed tomography (SPECT), ventilation-perfusion (V-Q) imaging, dual energy CT, and magnetic resonance angiography Contains 29 new chapters and includes new content on epidemiology of deep venous thrombosis; use of the new anticoagulants (dabigatran, rivaroxaban, and apixaban) for DVT and PE; indications and results with thrombolytic therapy and with vena cava filters; and information and indications for invasive mechanical thrombectomy and thrombolysis Written by an internationally recognized and respected expert in the field
From a local ballot initiative in Massachusetts, the nuclear weapons freeze movement has grown during the last three years into an important national issue. By 1983, Congress had been asked to consider more than two dozen freeze resolutions, and more than 25% of the voters in the U.S. had the opportunity to vote on state-wide and regional freeze initiatives. This book explores the issues behind the current debate over nuclear weapons and the freeze movement from a wide range of perspectives. The contributors assess the goals and implications of the freeze movement, examine its origins in religious and secular pacifism, explain the amendments to the original freeze proposal introduced in Congress, and discuss the reaction and policies of the Reagan administration. The nuclear freeze movement is placed in an international context with discussions of recent arms negotiations, European views of U.S. policies, and the possible effects of a freeze on NATO allies and on U.S. national security. The book includes a comprehensive annotated bibliography.
The Murray cod is Australia’s largest and most iconic freshwater fish. Tales of the species have long been part of Australian folklore and this book describes its history, biology, cultural significance and conservation. The Life and Times of the Murray Cod reveals the many roles the species has played throughout the history of the continent, from its place at the heart of the Aboriginal creation story of the Murray River, its role as a food source for explorers surveying inland Australia in the early 1800s, to it forming the basis of a commercial fishing industry up to the early 2000s. Living for upwards of half a century and growing to astonishing sizes, today the Murray cod is a hugely popular target for recreational fishing, but its future is anything but assured. In the face of climate change, river management and fishing pressure, much needs to be done to ensure this extraordinary fish swims confidently into the future. The Life and Times of the Murray Cod draws on historical, anecdotal and scientific sources to reveal what makes this remarkable species so special, and will appeal to fishers, natural resource managers, conservationists and any reader interested in natural history.
A 2017 CHOICE Outstanding Academic Title award winner *********************************************** This book is an introduction to the history of alcoholic drink in England from the end of the Middle Ages to the present day. Treating the subject thematically, it covers who drank, what they drank, how much, who produced and sold drink, the places where it was enjoyed and the meanings which drinking had for people. It also looks at the varied opposition to drinking and the ways in which it has been regulated and policed. As a social and cultural history, it examines the place of drink in society and how social developments have affected its history and what it meant to individuals and groups as a cultural practice. Covering an extended period in time, this book takes in the important changes brought about by the Reformation and the processes of industrialization and urbanization. This volume also focuses on drink in relation to class and gender and the importance of global developments, along with the significance of regional and local difference. Whilst a work of history, it draws upon the insights of a range of other disciplines which have together advanced our understanding of alcohol. The focus is England, but it acknowledges the importance of comparison with the experience of other countries in furthering our understanding of England’s particular experience. This book argues for the centrality of drink in English society throughout the period under consideration, whilst emphasizing the ways in which its use, abuse and how they have been experienced and perceived have changed at different historical moments. It is the first scholarly work which covers the history of drink in England in all its aspects over such an extended period of time. Written in a lively and approachable style, this book is suitable for those who study social and cultural history, as well as those with an interest in the history of drink in England.
This study explores the science and culture of nineteenth-century British arboretums. These were fostered by a variety of factors: global trade and exploration, popularity of collecting, significance to the British economy and society, developments in science, changes in landscape gardening aesthetics and agricultural and horticultural improvement.
A comprehensive introduction to mathematical and agent-based modeling of social behavior This book provides a unified, theory-driven introduction to key mathematical and agent-based models of social dynamics and cultural evolution, teaching readers how to build their own models, analyze them, and integrate them with empirical research programs. It covers a variety of modeling topics, each exemplified by one or more archetypal models, and helps readers to develop strong theoretical foundations for understanding social behavior. Modeling Social Behavior equips social, behavioral, and cognitive scientists with an essential tool kit for thinking about and studying complex social systems using mathematical and computational models. Combines both mathematical and agent-based modeling of social behavior Integrates cognitive science, social science, and cultural evolution Covers topics such as the philosophy of modeling, collective movement, segregation, contagion, polarization, the evolution of cooperation, the emergence of norms, networks, and the scientific process Discusses more advanced topics, including how to use models to build a more robust empirical research program An ideal introductory textbook for graduate students or advanced undergraduates An invaluable resource for practitioners
This two volume set contains comprehensive coverage of management of disorders of the adult hip. It includes all arthroscopic and open procedures as well as extensive coverage of equipment and prostheses.
This book is intended as an introductory text for students studying a wide range of courses concerned with animal management, zoo biology and wildlife conservation, and should also be useful to zookeepers and other zoo professionals. It is divided into three parts. Part 1 considers the function of zoos, their history, how zoos are managed, ethics, zoo legislation and wildlife conservation law. Part 2 discusses the design of zoos and zoo exhibits, animal nutrition, reproduction, animal behaviour (including enrichment and training), animal welfare, veterinary care, animal handling and transportation. Finally, Part 3 discusses captive breeding programmes, genetics, population biology, record keeping, and the educational role of zoos, including a consideration of visitor behaviour. It concludes with a discussion of the role of zoos in the conservation of species in the wild and in species reintroductions. This book takes an international perspective and includes a wide range of examples of the operation of zoos and breeding programmes particularly in the UK, Europe, North America and Australasia. Visit www.wiley.com/go/rees/zoo to access the artwork from the book.
A guide to treating psychosis that provides information on drug options and side-effects in order to allow for weighing treatment options knowledgably The Maudsley Guidelines on Advanced Prescribing in Psychosis offers a resource that puts the focus on the need to treat the individual needs of a patient. The authors – noted experts on the topic – offer an alternative to the one-size-fits-all treatment of psychosis and shows how to build psychiatrist and patient relationships that will lead to effective individual treatment plans. The book provides up-to-date data and information about commonly used anti-psychotic drugs and drugs used in bipolar disorder. The text weighs both the upsides and downsides of each pharmaceutical presented, and helps prescribers and patients weigh the costs and benefits of various options to reach an appropriate treatment plan. The authors highlight the treatment at a population level and the systems in which individual treatments take places. This important resource: Facilitates the tailoring of an appropriate treatment plan for clients manifesting signs of psychosis Offers a comparative strategy that helps gauge the suitability of one treatment plan over another Provides at-hand data and information about commonly used anti-psychotic drugs Includes an understanding of the origins and side-effects of each drug presented The Maudsley Guidelines on Advanced Prescribing in Psychosis offers psychiatrists and other mental health practitioners an essential guide for treating psychosis on an individualized level.
Major advances have been made in recent years in clarifying the molecular properties of the cytochrome P-450 system. These advances stem, in practical terms, from the generally recognized importance of cytochrome P-450 in the metabolism of drugs and in the bioactivation of xenobiotics to toxic products. The fascinating multiplicity and differential regulation of cytochrome P-450 isozymes, and their ability to catalyze extraordinarily difficult chemical transformations, have independently drawn many chemists and biochemists into the P-450 circle. Progress in the field, from a technical point of view, has been propelled by the de velopment of reliable procedures for the purification of membrane-bound enzymes, by the growing repertoire of molecular biological techniques, and by the development of chemical models that mimic the catalytic action of P-450. As a result, our understanding of the P-450 system is moving from the descriptive, pharmacological level into the tangible realm of atomic detail. The rapid progress and multidisciplinary character of the cytochrome P-450 field, which cuts across the lines that traditionally divide disciplines as diverse as inorganic chemistry and genetics, have created a need for an up-to-date evaluation of the advances that have been made. It is hoped that this book, with its molecular focus on the cytochrome P-450 system, will alleviate this need. The authors of the individual chapters have strived to emphasize recent results without sacrificing the background required to make their chapters comprehensible to informed nonspecialists.
From the development of each vaccine to its use in reducing disease, Plotkin's Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues – plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Covers the new oral cholera and zoster vaccines, as well as newly licensed meningococcal group B vaccines and a newly licensed dengue vaccine. - Brings you up to date on successful human trials of Ebola vaccines, an enterovirus 71 vaccine licensed in China, and new recommendations and changes to polio vaccines. - Features a new chapter on maternal immunization. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
From the latest vaccination evidence, recommendations, and protocols . . . to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. - Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. - Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. - Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. - Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
This book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter’s arrangement. The term "VLP" is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions. Key Features Presents the first full guide to the VLP nanotechnology, classified by current viral taxonomy Outlines specific structural properties and interconnection of the virions and VLPs Explains generation and characteristics of VLPs produced by various expression systems Offers up-to-date summary of VLPs designed as vaccines and delivery tools Unveils interconnection of VLPs with novel organic and inorganic nanomaterials
In the past ten years, heteroepitaxy has continued to increase in importance with the explosive growth of the electronics industry and the development of a myriad of heteroepitaxial devices for solid state lighting, green energy, displays, communications, and digital computing. Our ever-growing understanding of the basic physics and chemistry underlying heteroepitaxy, especially lattice relaxation and dislocation dynamic, has enabled an ever-increasing emphasis on metamorphic devices. To reflect this focus, two all-new chapters have been included in this new edition. One chapter addresses metamorphic buffer layers, and the other covers metamorphic devices. The remaining seven chapters have been revised extensively with new material on crystal symmetry and relationships, III-nitride materials, lattice relaxation physics and models, in-situ characterization, and reciprocal space maps.
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