Tales of Dorias: Kahlen’s Burden by Paul H. LeSage Paul H. LeSage shows us his imaginative process as he takes us to the beautiful, yet unpredictable continent of Dorias. Kahlen’s Burden shares just a glimpse into an adventurous world of monarchy and magic, while consistently introducing us to new characters we feel we’ve known for a lifetime. Just like Kahlen, we are along for a journey, but we have very little idea where we’re going next.
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. These phages played a unique role in early studies of molecular biology, the genetic code, translation, replication, suppression of mutations. Special attention is devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery, evolutionary and environmental studies. Included is an overview of the generation of novel vaccines, gene therapy vectors, drug delivery, and diagnostic tools exploring the role of RNA phage-derived products in the revolutionary progress of the protein tethering and bioimaging protocols. Key Features Presents the first full guide to single-stranded RNA phages Reviews the history of molecular biology summarizing the role RNA phages in the development of the life sciences Demonstrates how RNA phage-derived products have resulted in nanotechnological applications Presents an up-to-date account of the role played by RNA phages in evolutionary and environmental studies
First published in English 1968, in this volume Paul Fraisse begins with history, looking at the evolution of experimental psychology, starting with its origins. He then moves on to the establishment of experimental psychology around the world. In the second chapter he discusses the experimental method. In the third chapter Jean Piaget tackles the questions of explanation and parallelism and their problems within experimental psychology. The final chapter by Maurice Reuchlin goes on to discuss measurement in psychology looking at various scales with their experimental conditions and numerical properties.
Paul T. Kostecki, Associate Director, Northeast Regional Environment Public Health Center, School Of Public Health, University Of Massachusetts At Amherst, Received His Ph.D. From The School Of Natural Resources At The University Of Michigan In 1 980. He Has Been Involved With Human And Ecological Risk Assessment And Risk Management Research For The Last 12 Years. Dr. Kostecki Has Co-Authored And Co-Edited Over 50 Articles And 16 Books On Environmental Assessment And Cleanup Including: Remedial Technologies For Leaking Underground Storage Tanks, Soils Contaminated By Petroleum Products; Petroleum Contaminated Soils, Vols. 1 To 3: Hydrocarbon Contaminated Soils And Groundwater, Vols. 1 To 4; Hydrocarbon Contaminated Soils, Vols. 1 To 5; Principles And Practices For Diesel Contaminated Soils, Vols. 1 To 5; Sesoil In Environmental Fate And Risk Modeling, Contaminated Soils, Vol. 1 And Risk Assessment And Environmental Fate Methodologies.Dr. Kostecki Also Serves As Associate Editor For The Journal Of Soil Contamination, Chairman Of The Scientific Advisory Board For Soil And Groundwater Cleanup Magazine As Well As An Editorial Board Member For The Journal Of Human And Ecological Risk Assessment.In A Addition. Dr. Kostecki Serves As Executive Director For The Association For The Environmental Health Of Soils (Aehs) And Was The Scientific Advisor For The Workshop On Assessment And Remediation Of Oil Contaminated Soils Held In Kuwait 18-22 March 1995.Dr. Manaf Behbehani Obtained His B.S. In Biology From The University Of Akron, Usa (1969) And M.S. In Zoology From The Same University (1972). He Continued His Graduate Studies At The University Of New Hampshire Receiving Ph.D. In Marine Ecology And Invertebrates In 1978. Since Then, He Has Been Teaching Ecology And Marine Biology Courses At The Faculty Of Science, Kuwait University. From 1 982-1987, He Held The Post Of Marine Scientist At The Regional Organisation For The Protection Of The Marine Environment (Ropme) In Kuwait. Dr. Behbehani Has Worked On A Number Of Pioneering Research Projects, Namely To Study The Zooplankton Of Kuwaiti Waters And The Western Section Of The Arabian Gulf, And To Study The Distribution, Abundance And Taxonomy Of Marine Invertebrates Living In The Intertidal Zones Of Kuwait. He Has Published Several Scientific Articles And Has Served As External Examiner For Several Masters Thesis. From 1991-1995, Dr. Behbehani Was Vice-Dean For Planning And Laboratories At The Faculty Of Science, Kuwait University And Is Presently Chairman Of The National Biodiversity Committee, State Of Kuwait. He Was The Chairman Of The Scientific Committee For The Workshop On Assessment And Remediation Of Oil Contaminated Soils, The Proceedings Of Which Are Published In This Book.
This is the Second Edition of the popular Canadian adaptation of Brunner and Suddarth's Textbook of Medical-Surgical Nursing, by Day, Paul, and Williams. Woven throughout the content is new and updated material that reflects key practice differences in Canada, ranging from the healthcare system, to cultural considerations, epidemiology, pharmacology, Web resources, and more. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
The advances made in vascular biology in the last 25 years have considerably changed the perception that one could have of the endothelial cells. Once considered as a diffusion barrier preventing the access of the blood cells to the vascular matrix, the endothelium is now recognized as playing a major role in the control of blood fluidity, platelet aggregation, and vascular tone, but also in immunology, inflammation, angiogenesis, and for serving as a metabolizing and an endocrine organ. -- from the preface Cardiovascular diseases, so prevalent in the Western world during the twentieth century, could well become the scourge of the twenty-first century in emerging countries as well as the West. Endothelial dysfunction linked to an imbalance in the synthesis and/or release of contracting and relaxing factors is often evoked to explain the initiation of the cardiovascular pathology or its development and perpetuation. Two decades ago, when nitric oxide was demonstrated to mediate endothelium-dependent relaxations, the vascular world seemed convinced that nitric oxide was the ultimate and sole explanation for such relaxations. However not everyone agreed. EDHF: The Complete Story is the work of two leading researchers who did not accept that simple conclusion, but instead continued to search, along with others, for a deeper understanding of the ways in which endothelial cells communicate with the underlying smooth muscle to signal it to hyperpolarize. Now with most, if not all, of those ways, uncovered, the authors offer this summary as way of bringing closure to the quest. This monograph reports on the work of many researchers. It summarizes the significant recent discoveries concerning endothelium-dependent hyperpolarizations, which are likely to play a much more important role in cardiovascular physiology and pathology than was originally foreseen Extensively illustrated with original diagrams and schematics that summarize the different steps of endothelium-dependent hyperpolarization, the text is designed for vascular biologists, and cardiologists, as well as graduate students looking to gain an understanding of the intimate functioning of the blood vessel wall.
Despite spatial statistics and spatial econometrics both being recent sprouts of the general tree "spatial analysis with measurement"—some may remember the debate after WWII about "theory without measurement" versus "measurement without theory"—several general themes have emerged in the pertaining literature. But exploring selected other fields of possible interest is tantalizing, and this is what the authors intend to report here, hoping that they will suscitate interest in the methodologies exposed and possible further applications of these methodologies. The authors hope that reactions about their publication will ensue, and they would be grateful to reader(s) motivated by some of the research efforts exposed hereafter letting them know about these experiences.
Since the 1970s, American society has provided especially fertile ground for the growth of the Christian right and its influence on both political and cultural discourse. In Stations of the Cross political theorist Paul Apostolidis shows how a critical component of this movement’s popular culture—evangelical conservative radio—interacts with the current U.S. political economy. By examining in particular James Dobson’s enormously influential program, Focus on the Family—its messages, politics, and effects—Apostolidis reveals the complex nature of contemporary conservative religious culture. Public ideology and institutional tendencies clash, the author argues, in the restructuring of the welfare state, the financing of the electoral system, and the backlash against women and minorities. These frictions are nowhere more apparent than on Christian right radio. Reinvigorating the intellectual tradition of the Frankfurt School, Apostolidis shows how ideas derived from early critical theory—in particular that of Theodor W. Adorno—can illuminate the political and social dynamics of this aspect of contemporary American culture. He uses and reworks Adorno’s theories to interpret the nationally broadcast Focus on the Family, revealing how the cultural discourse of the Christian right resonates with recent structural transformations in the American political economy. Apostolidis shows that the antidote to the Christian right’s marriage of religious and market fundamentalism lies not in a reinvocation of liberal fundamentals, but rather depends on a patient cultivation of the affinities between religion’s utopian impulses and radical, democratic challenges to the present political-economic order. Mixing critical theory with detailed analysis, Stations of the Cross provides a needed contribution to sociopolitical studies of mass movements and will attract readers in sociology, political science, philosophy, and history.
This book covers all the relevant dictionary learning algorithms, presenting them in full detail and showing their distinct characteristics while also revealing the similarities. It gives implementation tricks that are often ignored but that are crucial for a successful program. Besides MOD, K-SVD, and other standard algorithms, it provides the significant dictionary learning problem variations, such as regularization, incoherence enforcing, finding an economical size, or learning adapted to specific problems like classification. Several types of dictionary structures are treated, including shift invariant; orthogonal blocks or factored dictionaries; and separable dictionaries for multidimensional signals. Nonlinear extensions such as kernel dictionary learning can also be found in the book. The discussion of all these dictionary types and algorithms is enriched with a thorough numerical comparison on several classic problems, thus showing the strengths and weaknesses of each algorithm. A few selected applications, related to classification, denoising and compression, complete the view on the capabilities of the presented dictionary learning algorithms. The book is accompanied by code for all algorithms and for reproducing most tables and figures. Presents all relevant dictionary learning algorithms - for the standard problem and its main variations - in detail and ready for implementation; Covers all dictionary structures that are meaningful in applications; Examines the numerical properties of the algorithms and shows how to choose the appropriate dictionary learning algorithm.
When Joegodson Déralciné was still a small child, his parents left rural Haiti to resettle in the rapidly growing zones of Port-au-Prince. As his family entered the city in 1986, Duvalier and his dictatorship exited. Haitians, once terrorized under Duvalier’s reign, were liberated and emboldened to believe that they could take control of their lives. But how? Joining hundreds of thousands of other peasants trying to adjust to urban life, Joegodson and his family sought work and a means of survival. But all they found was low-waged assembly plant jobs of the sort to which the repressive Duvalier regime had opened Haiti’s doors—the combination of flexible capital and cheap labour too attractive to multinational manufacturers to be overlooked. With the death of his mother, Joegodson was placed in his uncle’s care, and so began a childhood of starvation, endless labour, and abuse. In honest, reflective prose, Joegodson—now a father himself— allows us to walk in the ditches of Cité Soleil, to hide from the macoutes under the bed, to feel the ache of an empty stomach. But, most importantly, he provides an account of life in Haiti from a perspective that is rarely heard. Free of sentimentality and hackneyed clichés, his narrative explores the spirituality of Vodou, Catholicism, and Protestantism, describes the harrowing day of the 2010 earthquake and its aftermath, and illustrates the inner workings of MINUSTAH. Written with Canadian historian Paul Jackson—Joegodson telling his story in Creole, Jackson translating, the two of them then reviewing and reworking—the memoir is a true collaboration, the struggle of two people from different lands and vastly different circumstances to arrive at a place of mutual understanding. In the process, they have given us an unforgettable account of a country determined to survive, and on its own terms.
To celebrate the 270th anniversary of the De Gruyter publishing house, the company is providing permanent open access to 270 selected treasures from the De Gruyter Book Archive. Titles will be made available to anyone, anywhere at any time that might be interested. The DGBA project seeks to digitize the entire backlist of titles published since 1749 to ensure that future generations have digital access to the high-quality primary sources that De Gruyter has published over the centuries.
While most abnormal psychology texts seem to aim solely for breadth, the acclaimed Oxford Textbook of Psychopathology aims for depth, with a focus on adult disorders and special attention given to the personality disorders. Almost a decade has passed since the first edition was published, establishing itself as an unparalleled guide for professionals and graduate students alike, and in this second edition, esteemed editors Paul H. Blaney and Theodore Millon have once again selected the most eminent researchers in abnormal psychology to cover all the major mental disorders, allowing them to discuss notable issues in the various pathologies which are their expertise. This collection exposes readers to exceptional scholarship, a history of psychopathology, the logic of the best approaches to current disorders, and an expert outlook on what future researchers and mental health professionals will be facing in the years to come. With extensive coverage of personality disorders and issues related to classification and differential diagnosis, this volume will be exceptionally useful for all mental health workers, clinical psychologists, psychiatrists, and social workers, and as a textbook focused on understanding psychopathology in depth, as well as a valuable guide for graduate psychology students and psychiatric residents.
Takes a look at issues raised not only in Smollett's novels, for which he is usually remembered, but also in other works of this prolific Scottish author.
From diagnostic to therapeutic procedures, Endosonography, 3rd Edition is an easy-to-access, highly visual guide covering everything you need to effectively perform EUS, interpret your findings, diagnose accurately, and choose the best treatment course. World-renowned endosonographers help beginners apply endosonography in staging cancers, evaluating chronic pancreatitis, and studying bile duct abnormalities and submucosal lesions. Practicing endosonographers can learn cutting-edge techniques for performing therapeutic interventions such as drainage of pancreatic pseudocysts and EUS-guided anti-tumor therapy. Videos detailing various methods and procedures—and more—equip you with a complete overview of all aspects of EUS. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Get a clear overview of everything you need to know to establish an endoscopic practice, from what equipment to buy to providing effective cytopathology services. Understand the role of EUS with the aid of algorithms that define its place in specific disease states. Gain a detailed visual understanding and mastery of how to perform EUS systematically using illustrations, high-quality endosonography images, and videos. Glean all essential, up-to-date information about endosonography including transluminal drainage procedures, contrast-enhanced EUS, and fine-needle aspiration techniques. Benefit from the extensive knowledge and experience of world-renowned leaders in endosonography, Drs. Robert H. Hawes, Paul Fockens, and Shyam Varadarajulu. Locate information quickly and easily through a consistent chapter structure, with procedures organized by body system.
This book provides an overview of three generations of spatial econometric models: models based on cross-sectional data, static models based on spatial panels and dynamic spatial panel data models. The book not only presents different model specifications and their corresponding estimators, but also critically discusses the purposes for which these models can be used and how their results should be interpreted.
While the role of the university president has evolved dramatically in recent years, the recruitment pool and selection process have changed little since the 1960s. In Leadership Under Fire, Ross Paul combines leadership theory, interviews with eleven of Canada's most successful presidents, and thirty-five years of personal experience to shed light on the complexity and importance of leading a university and identifies some of the critical challenges and opportunities facing Canadian universities today. Paul illuminates some of the ways in which Canadian universities are unique and uses these differences to make clear the importance of organizational, cultural, and institutional fit for leaders confronting critical academic issues such as academic leadership and accountability, student success and support, university funding and fund-raising, strategic planning, government and community relations, and internationalism. His analysis reaffirms some long-standing practices, while arguing that changes are badly needed in others. While much has been written about university leadership elsewhere, Leadership Under Fire focuses on Canada and some of the men and women who have made a real difference to the quality of its post-secondary institutions. Paul builds on their stories to offer useful perspectives and advice at a time when the quality of universities was never more critical to the country’s economic, social, and political success.
Analysing the physiological adaptations of marine mammals and seabirds, this book provides a comprehensive overview of what allows these species to overcome the challenges of diving to depth on a single breath of air. Through comparative reviews of texts on diving physiology and behaviour from the last seventy-five years, Ponganis combines this research into one succinct volume. Investigating the diving performance of marine mammals and seabirds, this book illustrates how physiological processes to extreme hypoxia and pressure are relevant to the advancement of our understanding of basic cellular processes and human pathologies. This book underscores the biomedical and ecological relevance of the anatomical, physiological and molecular/biophysical adaptations of these animals to enable further research in this area. An important resource for students and researchers, this text not only provides an essential overview of recent research in the field, but will stimulate further research into the behaviour and physiology of diving.
Social research is a bourgeoning field. Of course it has many traditions and approaches, but there is a high premium upon thinking differently and thinking anew because social life is never static or wholly predictable. The Handbook, edited by internationally recognized scholars, provides a comprehensive, pitch-perfect critical assessment of the field. The main features of the Handbook are: Clear organization into 4 parts dealing with The Social Context of Research; Design and Data Collection; Integrating The Analysis of New Data Types; Sampling, Inference and Measurement Clear, cutting edge chapters on Objectivity; Causation; Organizing Social Research; Correspondence Analysis; Grounded Theory; Conversational Surveys; Mixed Methods; Meta-Analysis; Optimal Matching Analysis; GIS Analysis; Quantitative Narrative Analysis; Longitudinal Studies; SEM; MLM; Qualitative Comparative Analysis; Respondent Driven Sampling Brings together a glittering assembly of the key figures working in the field of research methods Demonstrates the continuities and productive tensions between classical traditions and real world research. The result is a superbly organized text which will be required reading for anyone interested in the routes and future of social research. It is an unparalleled teaching resource and a 'must have' for serious social researchers.
The oil crisis during the 1970s turned interest towards the utilization of renewable resources and towards lignocellulosics in particular. The 1970s were also the cradle period of biotechnology, and the years when biotechnical utilization of lignocellulosic waste from agriculture and forestry gained priori ty. This was a logical conclusion since one of nature's most important biologi cal reactions is the conversion of wood and other lignocellulosic materials to carbon dioxide, water and humic substances. However, while biotechnology in other areas like medicine and pharmacology concerned production of expen sive products on a small scale, biotechnical utilization and conversion of ligno cellulosics meant production of inexpensive products on a large scale. Biotechnical utilization of lignocellulosic materials is therefore a very difficult task, and the commercial utilization of this technology has not progressed as rapidly as one would have desired. One reason for this was the lack of basic knowledge of enzyme mechanisms involved in the degradation and conversion of wood, other lignocellulosics and their individual components. There are also risks associated with initiating a technical development before a stable platform of knowledge is available. Several of the projects started with en thusiasm have therefore suffered some loss of interest. Also contributing to this failing interest is the fact that the oil crisis at the time was not a real one. At present, nobody predicts a rapid exhaustion of the oil resources and fuel production from lignocellulosics is no longer a high priority.
From the latest vaccination evidence, recommendations, and protocols . . . to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. - Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. - Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. - Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. - Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
This book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter’s arrangement. The term "VLP" is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions. Key Features Presents the first full guide to the VLP nanotechnology, classified by current viral taxonomy Outlines specific structural properties and interconnection of the virions and VLPs Explains generation and characteristics of VLPs produced by various expression systems Offers up-to-date summary of VLPs designed as vaccines and delivery tools Unveils interconnection of VLPs with novel organic and inorganic nanomaterials
The first and ultimate guide for anyone working in transition organometallic chemistry and related fields, providing the background and practical guidance on how to efficiently work with routine research problems in NMR. The book adopts a problem-solving approach with many examples taken from recent literature to show readers how to interpret the data. Perfect for PhD students, postdocs and other newcomers in organometallic and inorganic chemistry, as well as for organic chemists involved in transition metal catalysis.
This textbook provides a comprehensive overview of international corporate reporting which enhances students’ understanding of diversity and convergence in the field. The authors discuss the institutional and cultural context in which international corporate reporting has developed over the years as well as the global reach of IFRS Standards from the IASB throughout and beyond the European Union, into interest groups and emerging economies. Other key elements explored throughout the book include assurance through auditing and corporate governance, narrative reporting, strategic and corporate social responsibility, group accounting, current accounting issues and taxation in corporate reports. Indicative research examples show how the methods used in research papers may be understood and applied. Case studies outline short projects based on corporate cases, with related links to material on corporate websites. Helpful and reliable sources of information and data are identified through hyperlinks to accessible websites. End-of-chapter questions encourage discussion of the main issues. Throughout there is a focus on accountability and the information needs of stakeholders. This new edition of a classic text is fully revised and updated in order to remain essential reading for students of international accounting and corporate reporting globally. The book will be an invaluable resource for postgraduate taught programmes and final-year undergraduate courses in accounting, finance and business studies.
Noting that working-class writers and editors actively sought to define for themselves the spiritual and political role literature played for an emerging working class, Murphy concludes that while there was no uniform working-class interpretation of literature, working-class journalists conducted a lively and continuing debate about literature, and that their agreements and disagreements show a thriving and evolving aesthetic.
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