When a group of Amish teenagers on their Rumschpringe test is torn apart by the murder of one and the abduction of another, Professor Michael Branden joins forces with Holmes County Sheriff Bruce Robertson and Pastor Cal Troyer to find a murderer and a kidnapper, break up a deadly drug ring, and find the missing teen, all the while struggling with the reluctance of the Amish to trust the law. Simultaneous.
Parkinsonism of various types has long been a debilitating and cruel affliction for significant numbers of people, and even today the cure remains elusive. The present volume explores the colorful and sometimes alarming history of the attempts to provide at least some relief from the symptoms of this disorder, commencing with interesting reports from ancient India and medieval Europe and continuing until the present time. Especial attention is devoted to L-DOPA therapy, still the leading pharmacological approach to the disorder more than forty years after its first application, and its place in the development of neurochemistry. But the employment of solanaceous plant alkaloid-based therapies, which dominated antiparkinsonian therapy until the mid-20th century, and the broad range of other approaches which found varying degrees of popularity, including those stimulated by the encephalitis epidemic which appeared in Europe during the First World War, are also discussed. The author concludes that antiparkinsonian therapy was never 'irrational', but was rather always determined by prevailing medical, pharmacological and scientific paradigms, so that its history is inextricably linked with experimental and clinical developments in these fields.
The main aim of this book is to give a self-contained and representative cross section through present-day research in solid-state physics. This covers metallic and mesoscopic transport, localization by disorder and superconductivity, including questions related to high-temperature superconductors and to heavy fermion systems. An important part of the book is devoted to itinerant-electron magnetism, discussing paramagnons, strong correlation, magnetization fluctuations and spin density waves. All the formal tools used in these chapters are developed in the first part of the book which contains a thorough discussion of second quantization and of perturbation theory for an arbitrary complex time path and also describes the functional approach to Feynman diagrams including general ward identities. Each chapter contains an extensive list of the relevant literature and a series of problems with detailed solutions which complement the main text. The book is meant both as a course and a research tool.
After a brief introduction to the main law of physics and fundamental concepts inherent in electromechanical conversion, Vector Control of Induction Machines introduces the standard mathematical models for induction machines – whichever rotor technology is used – as well as several squirrel-cage induction machine vector-control strategies. The use of causal ordering graphs allows systematization of the design stage, as well as standardization of the structure of control devices. Vector Control of Induction Machines suggests a unique approach aimed at reducing parameter sensitivity for vector controls based on a theoretical analysis of this sensitivity. This analysis naturally leads to the introduction of control strategies that are based on the combination of different controls with different robustness properties, through the use of fuzzy logic supervisors. Numerous applications and experiments confirm the validity of this simple solution, which is both reproducible and applicable to other complex systems. Vector Control of Induction Machines is written for researchers and postgraduate students in electrical engineering and motor drive design.
Transcranial magnetic stimulation (TMS) is a widely used non-invasive brain stimulation technique. It represents an exciting new frontier in neuroscience research and can be used to examine neural processes, providing insights into pathophysiology and treating a variety of neuropsychiatric illnesses. A Practical Guide to Transcranial Magnetic Stimulation Neurophysiology and Treatment Studies presents an overview of the use of TMS as both an investigational tool and as treatment for neurological and psychiatric disorders. The chapters include an overview of the history and basic principles of TMS and repetitive TMS (rTMS), the different types of TMS coils, different stimulation approaches, the use of neuronavigation, and safety considerations. The utility of single and paired TMS techniques to measure cortical inhibition, facilitation, connectivity and reactivity in motor and non-motor brain areas, the different methods of using TMS to induce brain plasticity, and use of TMS in cognitive studies are explored. It also covers TMS and rTMS combined with electroencephalography (EEG) in neurophysiological studies. The authors provide a summary of the clinical applications of TMS in neurological and psychiatric disorders including depression, schizophrenia, stroke, Parkinson disease, and pain. This up-to-date volume provides a compendious review of the use of TMS and rTMS that will help guide the utility of this methodology in both clinical and research settings. This practical guide will be a useful resource for those new to the field, as well as experienced users, for both research and clinical settings.
Written by one of the leading experts in the field, Paul Ekins, Stopping Climate Change provides a comprehensive overview of what is required to achieve ‘real zero’ carbon dioxide emissions by 2050, and negative emissions thereafter, which is the only way to stop human- induced climate change. This will require innovation in socio-technical systems, and in human behaviour, on an unprecedented scale. Stopping Climate Change describes the changes required to meet this goal: in technologies, social institutions and individual activities. Paul Ekins examines in detail issues around the supply and demand of energy and materials, and the efficiency of their use. It also analyses greenhouse gas removal technologies, offsetting and geoengineering, and plots the reduction of the non- CO2 greenhouse gas-emitting activities. Having set out the changes required, Ekins considers the economic implications, in terms of both the innovation and investments that are necessary to bring them about, and the effects that these are likely to have on national economies. The evidence presented points clearly to the economic impacts of decarbonisation being positive for the majority of countries, and for the world as a whole, even before considering the benefits of avoided climate change. When the health benefits of stopping the burning of fossil fuels are factored in, the global net benefits of decarbonisation are unequivocal. Drawing on examples from the UK and Europe, but with wider relevance at a global scale, Stopping Climate Change clearly shows how determined policy action at different levels could stop climate change. It will be of great interest to students, scholars and policymakers researching and working in the field of climate change and energy policy.
Practical Channel Hydraulics is a technical guide for estimating flood water levels in rivers using the innovative software known as the Conveyance and Afflux Estimation System (CES-AES). The stand alone software is freely available at HR Wallingford’s website www.river-conveyance.net. The conveyance engine has also been embedded within industry standard river modelling software such as InfoWorks RS and Flood Modeller Pro. This 2nd Edition has been greatly expanded through the addition of Chapters 6-8, which now supply the background to the Shiono and Knight Method (SKM), upon which the CES-AES is largely based. With the need to estimate river levels more accurately, computational methods are now frequently embedded in flood risk management procedures, as for example in ISO 18320 (‘Determination of the stage-discharge relationship’), in which both the SKM and CES feature. The CES-AES incorporates five main components: A Roughness Adviser, A Conveyance Generator, an Uncertainty Estimator, a Backwater Module and an Afflux Estimator. The SKM provides an alternative approach, solving the governing equation analytically or numerically using Excel, or with the short FORTRAN program provided. Special attention is paid to calculating the distributions of boundary shear stress distributions in channels of different shape, and to appropriate formulations for resistance and drag forces, including those on trees in floodplains. Worked examples are given for flows in a wide range of channel types (size, shape, cover, sinuosity), ranging from small scale laboratory flumes (Q = 2.0 1s-1) to European rivers (~2,000 m3s-1), and large-scale world rivers (> 23,000 m3s-1), a ~ 107 range in discharge. Sites from rivers in the UK, France, China, New Zealand and Ecuador are considered. Topics are introduced initially at a simplified level, and get progressively more complex in later chapters. This book is intended for post graduate level students and practising engineers or hydrologists engaged in flood risk management, as well as those who may simply just wish to learn more about modelling flows in rivers.
The first book to speak out against the pervasive influence of the American-Israeli Public Affairs Committee (AIPAC) on American politics, policy, and institutions resonates today as never before. With careful documentation and specific case histories, former congressman Paul Findley demonstrates how the Israel lobby helps to shape important aspects of U.S. foreign policy and influences congressional, senatorial, and even presidential elections. Described are the undue influence AIPAC exerts in the Senate and the House and the pressure AIPAC brings to bear on university professors and journalists who seem too sympathetic to Arab and Islamic states and too critical of Israel and its policies. Along with many longtime outspoken critics, new voices speaking out include former President Jimmy Carter, U.S. Representative Cynthia McKinney, Senator Robert Byrd, prominent Arab-American Dr. Ziad Asali, Rabbi Michael Lerner, and journalist Charles Reese. In addition, the lack of open debate among politicians with regard to the U.S. policy in the Middle East is lamented, and AIPAC is blamed in part for this censorship. Connections are drawn between America's unconditional support of Israel and the raging anti-American passions around the world--and ultimately the tragic events of 9/11. This replaces 1556520735.
The most comprehensive, multi-disciplinary text in the field, Cummings Otolaryngology: Head and Neck Surgery, 7th Edition, provides detailed, practical answers and easily accessible clinical content on the complex issues that arise for otolaryngologists at all levels, across all subspecialties. This award-winning text is a one-stop reference for all stages of your career—from residency and board certification through the challenges faced in daily clinical practice. Updated content, new otology editor Dr. Howard W. Francis, and new chapters and videos ensure that this 7th Edition remains the definitive reference in today's otolaryngology. - Brings you up to date with the latest minimally invasive procedures, recent changes in rhinology, and new techniques and technologies that are shaping patient outcomes. - Contains 12 new chapters, including Chronic Rhinosinusitis, Facial Pain, Geriatric Otology, Middle Ear Endoscopic Surgery, Pediatric Speech Disorders, Pediatric Cochlear Implantation, Tongue-Ties and Lip Ties, Laryngotracheal Clefts, and more. - Covers recent advances and new approaches such as the Draf III procedure for CRS affecting the frontal recess, endoscopic vidian and posterior nasal neurectomy for non-allergic rhinitis, and endoscopic approaches for sinonasal and orbital tumors, both extra- and intraconal. - Provides access to 70 key indicator (Accreditation Council for Graduate Medical Education Key Indicator Procedures), and surgical videos – an increase of 43% over the previous edition. - Offers outstanding visual support with 4,000 high-quality images and hundreds of quick-reference tables and boxes. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F. E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, helps you make a stronger connection between physiological principles and clinical practice; and more than 1,000 great new full-color illustrations help clarify complex concepts. You can also access the complete contents online at www.expertconsult.com. Deepen your grasp of the physiological principles that underlie visual acuity, color vision, ocular circulation, the extraocular muscle, and much more. Improve your understanding of physiology by referring to this totally updated volume--organized by function, rather than anatomy--and make a stronger connection between physiological principles and clinical practice. Better visualize information with a new, revamped format that includes 1,000 illustrations presented in full-color to better clarify complex concepts and functions. Access the most recent molecular, genetic, and biochemical discoveries affecting eye function, and gain fresh perspectives from a new, international editorial team. Search the entire contents online and download all the illustrations at www.expertconsult.com.
Now in its 6th edition, Cummings Otolaryngology remains the world's most detailed and trusted source for superb guidance on all facets of head and neck surgery. Completely updated with the latest minimally invasive procedures, new clinical photographs, and line drawings, this latest edition equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. Be certain with expert, dependable, accurate answers for every stage of your career from the most comprehensive, multi-disciplinary text in the field! Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. Experience clinical scenarios with vivid clarity through a heavily illustrated, full-color format which includes approximately 3,200 images and over 40 high quality procedural videos. Get truly diverse perspectives and worldwide best practices from a multi-disciplinary team of contributors and editors comprised of the world’s leading experts. Glean all essential, up-to-date, need-to-know information. All chapters have been meticulously updated; several extensively revised with new images, references, and content. Stay at the forefront of your field with the most updated information on minimally-invasive surgical approaches to the entire skull base, vestibular implants and vestibular management involving intratympanic and physical therapy-based approaches, radiosurgical treatment of posterior fossa and skull base neoplasms, and intraoperative monitoring of cranial nerve and CNS function. Apply the latest treatment options in pediatric care with new chapters on pediatric sleep disorders, pediatric infectious disease, and evaluation and management of the infant airway. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference. Manage many of the most common disorders with treatment options derived from their genetic basis. Assess real-world effectiveness and costs associated with emergent technologies and surgical approaches introduced to OHNS over the past 10 years. Incorporate recent findings about endoscopic, microscopic, laser, surgically-implantable, radiosurgical, neurophysiological monitoring, MR- and CT-imaging, and other timely topics that now define contemporary operative OHNS. Take it with you anywhere! With Expert Consult, you'll have access the full text, video clips, and more online, and as an eBook - at no additional cost!
DNA technology is evolving rapidly, with new methods and a fast-growing vocabulary. This unique dictionary offers current, detailed and accessible information on DNA technology to lecturers, researchers and students throughout the biomedical and related sciences. The third edition is a major update, with over 3000 references from mainstream journals and data from the very latest research – going well beyond the remit of most science dictionaries. It provides clear explanations of terms, techniques, and tests, including commercial systems, with detailed coverage of many important procedures and methods, and includes essay-style entries on many major topics to assist newcomers to the field. It covers topics relevant to medicine (diagnosis, genetic disorders, gene therapy); veterinary science; biotechnology; biochemistry; pharmaceutical science/drug development; molecular biology; microbiology; epidemiology; genomics; environmental science; plant science/agriculture; taxonomy; and forensic science.
Now in its Fifth Edition, this classic text provides a systematic approach to the anatomic localization of clinical problems in neurology. It offers clinicians a roadmap for moving from the symptom or observed sign to the place in the central or peripheral nervous system where the problem is. Clear discussions by three well-known authors provide a full understanding of why a symptom or sign can be localized to a particular anatomic area. More than 100 illustrations demonstrate relevant anatomy. This edition has been thoroughly updated and includes new charts to aid in differential diagnosis of various neurologic findings and disorders.
Army JAG lawyer Captain Mark Sanders cannot get over the harsh twenty-five year prison sentence levied against his client, Sergeant Keyshawn Adams, for one simple reason: he believes Adams did not brutally rape his ex-girlfriend. Determined to prove his gut instincts and reverse the conviction of Adams, Sanders seeks the assistance of a DNA expert, reinterviews every possible witness, and hires private investigator Dale Owens to track down potential witnesses who were unavailable for the trial. But when a strong suspicion points to the guilt of someone resembling the young sergeant, Sanders and Owens learn two valuable lessons: the toughest cases are when you believe your client, and what matters are not ones beliefs, but what can be proven in a court of law. In this fast-paced legal thriller, an army JAG lawyer must confront doubts, fears, and risks in an effort to find the truth and hopefully right a wrong.
This book covers two aspects of the career of D Allan Bromley: the science policy aspect and the scientific aspect.In the first half of the book, contributions from Governor John Sununu, former White House Chief of Staff under President George H W Bush; Neal Lane, former Science Adviser to President William Clinton; John Marburger III, Science Adviser to President George W Bush; and Mary Good, former Undersecretary of Commerce, highlight the role of Bromley as Science Adviser to President George H W Bush and a maker of science policy in the second part of the 20th Century. This part is of interest to science policy scholars, historians, and young persons wishing to start a career in science policy.In the second half of the book, articles by directors of laboratories and leading scientists discuss future programs in all areas of nuclear physics ? low-energy, medium-energy and high-energy ? to which Bromley greatly contributed, in the USA, Europe and Japan. This part of the book is of interest to all researchers in the field of nuclear physics, as it provides a comprehensive but succinct overview of the field and indicates directions for future research in the first part of the 21st century.
Pediatric Life Care Planning and Case Management provides a comprehensive and unique reference that goes beyond the clinical discussion to include legal and financial aspects, life expectancy data, and assistive technology. It also includes case samples of actual plans related to specific conditions. The book is divided into five parts: Normal Grow
Get to grips with the fundamentals of the Ruby programming language and learn how to build your own applications with the help of real-world examples and hands-on activities Key FeaturesLearn the fundamentals of Ruby object-oriented programming (OOP)Use the Ruby on Rails framework to build interactive web applicationsDiscover how to quickly build complex programs with fewer lines of codeBook Description The beauty of Ruby is its readability and expressiveness. Ruby hides away a lot of the complexity of programming, allowing you to work quickly and 'do more' with fewer lines of code. This makes it a great programming language for beginners, but learning any new skill can still be a daunting task. If you want to learn to code using Ruby, but don't know where to start, The Ruby Workshop will help you cut through the noise and make sense of this fun, flexible language. You'll start by writing and running simple code snippets and Ruby source code files. After learning about strings, numbers, and booleans, you'll see how to store collections of objects with arrays and hashes. You'll then learn how to control the flow of a Ruby program using boolean logic. The book then delves into OOP and explains inheritance, encapsulation, and polymorphism. Gradually, you'll build your knowledge of advanced concepts by learning how to interact with external APIs, before finally exploring the most popular Ruby framework ? Ruby on Rails ? and using it for web development. Throughout this book, you'll work on a series of realistic projects, including simple games, a voting application, and an online blog. By the end of this Ruby book, you'll have the knowledge, skills and confidence to creatively tackle your own ambitious projects with Ruby. What you will learnMaster the syntax and features of Ruby to build useful applicationsUse common design patterns to simplify code and improve efficiencyUnderstand how to implement object-oriented programming with RubyExplore ways to fetch, process, and output dataWork with public APIs and create reusable RubyGemsDebug code to troubleshoot application behaviorCreate interactive web applications with Ruby on RailsWho this book is for The Ruby Workshop is designed for anyone who is new to Ruby and wants a practical introduction to the language. Whether you're completely new to programming, or have experience in another language and want to broaden your skillset, this book will quickly get you up and running.
For portable, quick access to information needed at the point of care in today's cath lab, look no farther than Kern's Cardiac Catheterization Handbook, 7th Edition. This detailed, authoritative guide is ideal for cardiologists who need a quick clinical primer on cardiac catheterization, as well as for all members of the cardiac cath team. Highly readable and accessible, it helps you provide optimal patient care with reliable information on the latest diagnostic and treatment advances in this fast-paced field. - Provides clear instructions on what to expect, what to avoid, and how to manage complications for every procedure you'll encounter – including coverage of new techniques and technologies that affect virtually all aspects of familiar procedures. - Covers all the newest catheterization techniques for vascular closure and expansion of large-bore access procedures, including TAVR, ECMO, mitraclip, and TMVR. - Features a new chapter on intracardiac echocardiography and intraprocedural imaging. - Discusses key topics such as intra-procedural imaging, management of complications with algorithms that expedite the approach to these patients, adjunctive hemodynamic support, and maintaining quality in the laboratory. - Incorporates an increased emphasis on indications and contraindications for procedures in the context of a multidisciplinary heart team approach. - Includes numerous clear illustrations to enhance your understanding of the material, as well as videos of Dr. Kern demonstrating various procedures in the cath lab. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
In recent decades, cognitive neuroscience research has increased our understanding of how the brain learns, retains, and recalls information. At the same time, social psychologists have developed insights into group dynamics, exploring what motivates individuals in a group to give their full effort, or conversely, what might instead inspire them to become free loaders. Art and Science in the Choral Rehearsal explores the idea that choral conductors who better understand how the brain learns, and how individuals within groups function, can lead more efficient, productive, and enjoyable rehearsals. Armed with this knowledge, conductors can create rehearsal techniques which take advantage of certain fundamental brain and social psychology principles. Through such approaches, singers will become increasingly engaged physically and mentally in the rehearsal process. Art and Science in the Choral Rehearsal draws from a range of scientific studies to suggest and encourage effective, evidence-based techniques, and can help serve to reset and inspire new approaches toward teaching. Each chapter outlines exercises and creative ideas for conductors and music teachers, including the importance of embedding problem solving into rehearsal, the use of multiple entry points for newly acquired information, techniques to encourage an emotional connection to the music, and ways to incorporate writing exercises into rehearsal. Additional topics include brain-compatible teaching strategies to complement thorough score study, the science behind motivation, the role imagination plays in teaching, the psychology of rehearsal, and conducting tips and advice. All of these brain-friendly strategies serve to encourage singers' active participation in rehearsals, with the goal of motivating beautiful, inspired, and memorable performances.
Wolfgang Hilbig is a writer who is widely acknowledged as one of the most important to have emerged from the former GDR. In this study, the first in English, Paul Cooke explores the interplay of aesthetic and social ‘taboos’, as defined by the official discourse of the GDR, in a cross-section of Hilbig’s critical writing, poetry and prose. The protagonists in Hilbig’s texts suffer from a profound crisis of identity due to the disparity between the state’s official presentation of life in the East and their own experience. Cooke argues that through their exploration of the ‘taboo’, i.e. that which is excluded from the state’s official discourse, Hilbig’s characters attempt to break through the banal rhetoric of the ruling elite in order to realise an authentic sense of self.
Criminal Law: Case Studies and Controversies eschews traditional reliance on judicial opinions in favor of an innovative and dynamic method of criminal law instruction that is centered on statutory interpretation and case studies. Examination of real-world problems allows first-year law students to not only develop familiarity with the criminal law doctrine necessary for potential careers as prosecutors or defense attorneys, but also hone crucial skills for lawyering in general. Provocative case studies provide background for engaging class discussion and challenge students to tackle applying doctrine in real-world situations. When useful, the book provides actual cases from a variety of jurisdictions to further illuminate the concepts with which students have already been forced to grapple. New to the Fifth Edition: Additional and updated case studies and discussion material informed by the professors’ teaching experiences and designed to reinforce issues at the forefront of modern criminal law Streamlined chapters throughout the whole casebook for a more efficient and concise textbook. Professors and students will benefit from: Use of an innovative case studies method – Each topic area includes a detailed story about the people and events leading up to the offense Inclusion of photographs related to the crimes so students can better contextualize issues “Core opinions” of central historical, theoretical, or doctrinal importance in each subject-area section Provocative and timely principal cases from a wide variety of jurisdictions, each followed by the statutes that existed in the jurisdiction at the time of the offense Treatise-like summaries of law in each topic area give students an overview of the law, introduce the underlying theoretical principles, and provide context
The first history of the Detroit Symphony Orchestra to describe and document its origins in 1887 to the present day, relating its changing fortunes in light of the economic, demographic, and cultural history of the city of Detroit. The Detroit Symphony Orchestra: Grace, Grit, and Glory details the history of the Detroit Symphony Orchestra as seen through the prism of the city it has called home for nearly 130 years. Now one of America’s finest orchestras, the Detroit Symphony Orchestra began in 1887 as a rather small ensemble of around thirty-five players in a city that was just emerging as an industrial powerhouse. Since then, both the city and its orchestra have known great success in musical artistry for the symphony and economic influence for the city. They have each faced crises as well—financial, social, and cultural—that have forced the DSO into closure three times, and the city to the brink of dissolution. Yet somehow, in the face of adversity, the DSO stands strong today, a beacon of perseverence and rebirth in a city of second chances. This is the first history of the DSO to document the orchestra from its earliest incarnation in the late nineteenth century to its current status as one of the top orchestras in the country. The Detroit Symphony Orchestra tells the story of the organization—the musicians, the musical directors, the boards, and the management—as they strove for musical excellence, and the consistent funding and leadership to achieve it in the changing economic and cultural landscape of Detroit. Author Laurie Lanzen Harris, with Paul Ganson, explores the cycles of glory, collapse, and renewal of the orchestra in light of the city’s own dynamic economic, demographic, and cultural changes. Any reader with an interest in Detroit history or the history of American smphony orchestras should have this book on his or her shelf.
The great deltas of the globe have been threatened for several decades but their decline now appears to be inevitable; they are receding and losing the fertility that supports their tens of millions of inhabitants. Our deltas are victims of the dramatic deterioration in the volume of continental sediment brought by rivers to the oceans. By nature, deltas are fragile eco- and geological organisms. For centuries, they have been subject to human actions in the Mediterranean and European world, and today a deep crisis is affecting the great tropical deltas. A chapter is also devoted to concerns facing the Mississippi, an “aging delta of the new world”. Sedimentary Crisis at the Global Scale 2 discusses possible strategies to protect the deltas of the world – or at least adapt them and their dependencies to the changes they face. Several models are possible, including comprehensive protection (such as in the Netherlands) and cautious and respectful opening to the forces of the oceans in an environment-first perspective.
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