Parkinsonism of various types has long been a debilitating and cruel affliction for significant numbers of people, and even today the cure remains elusive. The present volume explores the colorful and sometimes alarming history of the attempts to provide at least some relief from the symptoms of this disorder, commencing with interesting reports from ancient India and medieval Europe and continuing until the present time. Especial attention is devoted to L-DOPA therapy, still the leading pharmacological approach to the disorder more than forty years after its first application, and its place in the development of neurochemistry. But the employment of solanaceous plant alkaloid-based therapies, which dominated antiparkinsonian therapy until the mid-20th century, and the broad range of other approaches which found varying degrees of popularity, including those stimulated by the encephalitis epidemic which appeared in Europe during the First World War, are also discussed. The author concludes that antiparkinsonian therapy was never 'irrational', but was rather always determined by prevailing medical, pharmacological and scientific paradigms, so that its history is inextricably linked with experimental and clinical developments in these fields.
Over a decade has passed since the original edition of The Clinician's Guide to Dermatologic Differential Diagnosis first came out. This massive two volume, second edition undertaking features over 4,000 new photographs of rare and puzzingly symptoms, 98 new chapters, and presents a complete update on all references and new findings since the original publication. This two volume set is designed to assist in the diagnosis of skin disease by presenting a unique and comprehensive approach to differential diagnosis. Organized alphabetically by physical finding each book in the set is meticulously put together for utility and usability. Volume 1 features a comprehensive list of the variety of physical findings a patient might have. It is the text of the work. Volume 2 serves as the atlas with which to cross reference a physical finding. It includes over 10,000 patient photos and strives to feature the rarer, more difficult to encounter pictures to arm the reader with knowledge beyond the basic. Created purely with the reader in mind, The Clinician's Guide to Dermatologic Differential Diagnosis, 2nd Edition strives to enhance the learning and teaching of differential diagnosis within dermatology. These texts are for the patient that defies diagnosis, going through checklists of diseases ensures that no clue is missed in aiding the patient. The sincere hope is that these companion volumes will be helpful in all clinical setting from medical clinic and other specialty clinics to the Dermatology clinic, from medical students to attendings, and from the nurses to the physicians assistants, whether in the academic setting or in the community environment anywhere in the world.
Traces the development of racial hygiene theory and eugenics research in Germany from the end of the 19th century through the Third Reich. Discusses particularly the work of Alfred Ploetz, a leading propagator of racial hygiene, and his anti-Jewish views. It was argued that German medical science had fallen prey to the "Jewish spirit" and was thus in need of reform. Argues that the biological, medical, and anthropological variants of racism were not only concerned with antisemitism but also influenced Nazi health and social policy. Eugenicists of Jewish origin became victims of the system they had helped to construct. Analyzes how racial hygiene theories were incorporated into Hitler's racial antisemitism and became the basis for the Nazi sterilization and euthanasia programs which, in turn, became the basis for the mass murder of the Jews.
During the First World War, delousing became routine for soldiers and civilians following the recent discovery that the louse carried typhus germs. But how did typhus come to be viewed as a "Jewish disease" and what was the connection between the anti-typhus measures during the First World War and the Nazi gas chambers in the Second World War? In this powerful book, Professor Weindling draws upon wide-ranging archival research throughout East and Central Europe to the United States, to provide valuable new insight into the history of German medicine from its response to the perceived threat of typhus epidemics from its Eastern borders. He examines how German experts in tropical medicine took an increasingly racialised approach to bacteriology, regarding supposedly racially inferior peoples as carriers of the disease.So they came to view typhus as a "Jewish" disease. By the Second World War as migrants and deportees had become conditioned to expect the ordeal of delousing at border crossings, ports, railway junctions and on entry to camps, so sanitary policing became entwined with racialisation as the Germans sought to eradicate typhus by eradicating the perceived carriers. Typhus had come to assume a new and terrifying genocidal significance, as the medical authorities sealed the German frontiers against diseased undesirables from the east, and gassing became a favoured means of disease eradication.
There is increasing awareness that the autonomic nervous system, through its central and peripheral pathways, plays a critical role in the regulation of the circulation. Peripherally, the autonomic representation, largely that of sympathetic nerves, innervate virtually all segments of the vascular tree as well as the adrenal medulla. Through the interaction of nerve terminals, their transmitters, receptors and intracellular mediators in smooth muscle, sympathetic neurons control vascular tone as well as the basal performance of the heart. In turn, the performance of the autonomic nervous system is highly controlled by the brain. Once viewed as a black box with only a vague influence on cardiovascular performance, the introduction of concepts and techniques of neuroscience into the field of cardiovascular medicine has led to the realization of the critical role of this organ in cardiovascular control. It is now well recognized that within the brain, the represenation of cardiovascular function is highly restricted anatomically, engages a number of specific transmitters for its actions, and has highly selective and topographically restricted functions to influence circulatory performance.
Annotation Trainee and practicing rheumatologists The study of disease genetics arguably began in rheumatology, with the description of the hereditary basis of alkaptonuria by Garrod in 1902, and the introduction of the concept of in-born errors of metabolism. A large proportion of the diseases seen by rheumatologists have genetic influences. The dissection of the genetic basis of rheumatic diseases has moved rapidly over the past 15 years. Increasingly, rheumatologists are being asked the question "How likely is it that my children will develop the disease I have?', and about the utility of genetic testing for those diseases. This book is not a hefty tome full of genetics jargon, but a quick reference source for doctors written to help answer those questions.
Featuring over 500 full-color clinical photographs, succinct clinical pearls, and detailed differential diagnosis tables, this atlas is a visual guide to the rapid and accurate diagnosis and appropriate treatment of pediatric problems. The book will greatly assist busy practitioners in recognizing disease entities and distinguishing among entities that appear similar. The Second Edition includes information on treatment, a chapter on breastfeeding images that demonstrate proper latch, and 150 new images. Organized by anatomic site, the book focuses on presenting problems. Each chapter includes bulleted clinical pearls on the history and physical examination. A differential diagnosis table lists all common diagnoses with ICD-9 codes and the distinguishing characteristics for each diagnosis. Clinical photographs of each entity are then shown, including ethnic variations where relevant.
Leukoderma is a generic term for any pigmentary dilution, be it congenital or acquired, circumscribed or generalized, devoid of or partially lacking in pig mentation. In the approach to the diagnosis of leukoderma, we have generally first considered the age of onset, whether leukoderma was congenital or ac quired, the extent and pattern of involvement, and the degree of pigmentary dilution. The organization of this monograph reflects this approach. For ex ample, we have separated the section devoted to various disease entities into diffuse and circumscribed leukoderma and the latter into various etiologies such as genetic, metabolic, infectious, and endocrinologic. One of several justifications for this monograph is to present an approach to the diagnosis of leukoderma, as detailed in Part II. In formulating a guide for the physician, we have found some limitations to our previous approach; we therefore offer the following new classification based upon a clini cal-pathologic correlation. This could provide the means to describe both the clinical and pathologic findings in one term.
Now in its 6th edition, Cummings Otolaryngology remains the world's most detailed and trusted source for superb guidance on all facets of head and neck surgery. Completely updated with the latest minimally invasive procedures, new clinical photographs, and line drawings, this latest edition equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. Be certain with expert, dependable, accurate answers for every stage of your career from the most comprehensive, multi-disciplinary text in the field! Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. Experience clinical scenarios with vivid clarity through a heavily illustrated, full-color format which includes approximately 3,200 images and over 40 high quality procedural videos. Get truly diverse perspectives and worldwide best practices from a multi-disciplinary team of contributors and editors comprised of the world’s leading experts. Glean all essential, up-to-date, need-to-know information. All chapters have been meticulously updated; several extensively revised with new images, references, and content. Stay at the forefront of your field with the most updated information on minimally-invasive surgical approaches to the entire skull base, vestibular implants and vestibular management involving intratympanic and physical therapy-based approaches, radiosurgical treatment of posterior fossa and skull base neoplasms, and intraoperative monitoring of cranial nerve and CNS function. Apply the latest treatment options in pediatric care with new chapters on pediatric sleep disorders, pediatric infectious disease, and evaluation and management of the infant airway. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference. Manage many of the most common disorders with treatment options derived from their genetic basis. Assess real-world effectiveness and costs associated with emergent technologies and surgical approaches introduced to OHNS over the past 10 years. Incorporate recent findings about endoscopic, microscopic, laser, surgically-implantable, radiosurgical, neurophysiological monitoring, MR- and CT-imaging, and other timely topics that now define contemporary operative OHNS. Take it with you anywhere! With Expert Consult, you'll have access the full text, video clips, and more online, and as an eBook - at no additional cost!
The highly anticipated update of the complete textbook of dermatologic science and practice focusing on the care of patients with moderately to heavily pigmented skin – 21 new chapters with more than 900 photographs! Dermatology for Skin of Color, Second Edition is a comprehensive reference that thoroughly details every aspect of dermatologic science as it applies to skin of color – from the development of the skin to the biology of hair and nails. All commonly encountered dermatologic problems of Africans, Asians, Arabs, Native Americans, and other peoples are covered, as are other diseases with significant skin manifestations. This second edition is significantly expanded with 21 new chapters covering dermatology for geriatric, adolescent, and pregnant patients, as well as depigmenting agents, viral infections, cutaneous manifestation of internal malignancy, neurofibromatosis, tuberous sclerosis, photoaging, photosensivity, laser treatment for skin-tightening, toxins and fillers, cosmetic practices in Mexico, effects of tattooing and piercing, sickle cell disease, drug eruptions, and the biology of oral mucosa. It also features many more clinical pictures and improved organization. Extensively illustrated with more than 900 full-color photos, Dermatology for Skin of Color provides comprehensive coverage of medical, surgical, and cosmetic treatment options, pediatric dermatology, differences between skin of color and Caucasian skin, differences between ethnic groups with skin of color, and important basic science information on the structure and function of skin of color. In addition, folk remedies and over-the-counter treatments specifically targeting this population are covered.
Netter's Pediatrics, edited by Drs. Todd Florin and Stephen Ludwig, is a rich visual aid with more than 500 images by Dr. Frank Netter and other artists working in his style that will help you diagnose and care for children with common clinical conditions. This is the first time that Netter's drawings of pediatric illness are brought together in a single volume. The superb, accurate artwork accompanies up-to-date text contributed by physicians at the prestigious Children's Hospital of Philadelphia. The book provides you with all the at-a-glance information you need for a quick overview of common issues from nutrition, allergy, infectious disease, and adolescent medicine, to cancer and heart disease. This user-friendly, clinical reference is also a great tool for patient and staff education. - Efficiently review key details for each condition with 500 detailed, crystal-clear images provided by Frank H. Netter and others working in the Netter tradition. - Apply dependable, concise, clinical advice from a team of physicians at Children's Hospital of Philadelphia, one of the top children's hospitals in the U.S. - Get answers at a glance during pediatric rotations when studying for exams or preparing for consultations.
Neale’s Disorders of the Foot remains the essential resource for students and practitioners of podiatry. All the common conditions encountered in day-to-day podiatric practice are reviewed and their diagnoses and management described along with areas of related therapeutics. Students will find in this one volume everything they need to know about foot disorders and their treatment in order to pass their examinations, while practitioners will continue to appreciate the book’s accessibility and relevance to their daily practice. The new eighth edition is more indispensable than ever before with all contributions revised and brought up to date, colour photographs throughout, an all-new clear and accessible full colour design, and its own website including a full image library, video clips of key techniques and interactive self-assessment questions. Whether you need quick reference or more detailed information, the new and improved Neale’s Disorders of the Foot is ready to serve the needs of a new generation of podiatry students and practitioners.
The most comprehensive, multi-disciplinary text in the field, Cummings Otolaryngology: Head and Neck Surgery, 7th Edition, provides detailed, practical answers and easily accessible clinical content on the complex issues that arise for otolaryngologists at all levels, across all subspecialties. This award-winning text is a one-stop reference for all stages of your career—from residency and board certification through the challenges faced in daily clinical practice. Updated content, new otology editor Dr. Howard W. Francis, and new chapters and videos ensure that this 7th Edition remains the definitive reference in today's otolaryngology. - Brings you up to date with the latest minimally invasive procedures, recent changes in rhinology, and new techniques and technologies that are shaping patient outcomes. - Contains 12 new chapters, including Chronic Rhinosinusitis, Facial Pain, Geriatric Otology, Middle Ear Endoscopic Surgery, Pediatric Speech Disorders, Pediatric Cochlear Implantation, Tongue-Ties and Lip Ties, Laryngotracheal Clefts, and more. - Covers recent advances and new approaches such as the Draf III procedure for CRS affecting the frontal recess, endoscopic vidian and posterior nasal neurectomy for non-allergic rhinitis, and endoscopic approaches for sinonasal and orbital tumors, both extra- and intraconal. - Provides access to 70 key indicator (Accreditation Council for Graduate Medical Education Key Indicator Procedures), and surgical videos – an increase of 43% over the previous edition. - Offers outstanding visual support with 4,000 high-quality images and hundreds of quick-reference tables and boxes. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
The only see-it-and-believe-it guide to whole-body self-diagnosis! Worried about that not-so-distinct mole? Has an online search led you to believe that you're suffering from neurodermatitis, nasal polyps, or elephantitis? Do you slather on a bottle of sanitizer daily or avoid others like they have the plague? Don't quarantine yourself just yet—trust your own eyes! Thanks to the help and humor of Paul Kleinman, you can learn and laugh about what you've got and what you're coming down with, all by looking at your body. Prognoses include: Dry, brittle hair is a symptom of hypothyroidism. Looks like you're running low on hormones or moisturizing shampoo. . . . White patches on your feet could mean you have pitted keratolysis. Great, so a colony of bacteria decided to move in or you forgot to use your antiperspirant again. . . A rash from cheek to cheek could be a sign of lupus. Don't fret—your insides might be at war with an inflammatory disease or you may just need a higher SPF . . . Drawn from real tenets of traditional medicine, modern research, and alternative practices, this tongue-in-cheek health guide will scratch your cyberchondriac's itch for information.
Good Day! , the critically-acclaimed biography about the legendary Paul Harvey, is now in paperback! In this heartwarming book, author Paul J. Batura tells the all-American story of one of the best-known radio voices in history. From his humble beginnings to his unparalleled career of more than 50 years with ABC radio, Paul Harvey narrated America's story day by day, through wars and peace, through the threat of communism and the crumbling of old colonial powers, through consumer booms and eventual busts.
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