This book is a follow up to Goitre Monitor: The History of Iodine Deficiency in Tasmania, published in 2006. Since that time climate change has played a major role in the delivery and availability of iodine to land masses, along with the role of iodophors and the mandatory fortification of bread with iodised salt in Australia and New Zealand over the past 15 years. Several academic colleagues have been invited to discuss the status of iodine from the UK, NZ and Australian perspective in individual chapters, as well as a contribution to the final chapter which discusses 'What the Future Holds' for the delivery and availability of iodine to sustain sufficiency and avoid deficiency of iodine in a changing world.
This textbook provides authoritative and up-to-date coverage of the classification, causes, treatment and prevention of psychological disorders in children.
Multiple attribute decision making (MADM) procedures, a process for making preference decisions over the available alternatives which are characterized by multiple (usually conflicting) attributes are useful for improving decision making in a wide range of circumstances--from professional to managerial to political. Using real-world case examples, the authors introduce the reader to normative (for optimal decisions) MADM models. Beginning in chapter 2 with and introductions to the various attributes in a decision, the authors explore how MADM methods can be used for descriptive purposes to model the existing decision-making process, noncompensatory and scoring methods, accommodation of soft data, construction of a multiple decision support system, and the validity of methods. The authors also include a presentation of the advanced procedures of TOPSIS and ELECTRE. This manual offers social scientists an encapsulated view of MADM methods, their characteristics, applicability, and the methods for solving MADM problems.
The essential multidisciplinary guide for the prevention and management of vascular injury from master skull base surgeons Vascular injury is the most significant source of morbidity or mortality during skull base surgery, regardless of the surgical approach. While skull base approaches always placed arteries and veins at risk, newer endoscopic endonasal approaches have introduced new challenges for the prevention and management of vascular injury. Greater anatomic knowledge, additional surgical options, improved instrumentation, advances in interventional neuroradiology, and enhanced training all contribute to successful outcomes. Vascular Challenges in Skull Base Surgery by renowned skull base experts Paul Gardner, Carl Snyderman, Brian Jankowitz, and distinguished contributors, fills a gap in the literature, with invaluable guidance on managing rare but potentially catastrophic surgical complications. The full range of surgical approaches to the anterior, middle, and posterior cranial fossae are covered in 22 chapters. Diverse topics encompass open and endoscopic endonasal surgical approaches, endovascular techniques including balloon test occlusion and embolization, and standard and alternative bypass procedures. The last three chapters discuss venous considerations, neurophysiologic monitoring, and the role of training and simulation in vascular injury prevention. Key learning points, illustrated discussion of relevant anatomy, and tips and tricks are targeted at helping skull base surgeons leverage practical strategies to improve patient outcomes. Key Highlights An impressive group of expert, highly-experienced surgeons share firsthand knowledge Insightful analyses of root causes and clinical pearls provide indispensable prevention tactics High-quality images and videos enhance visual understanding of surgical anatomy and techniques Trainees and practicing skull base surgeons will greatly benefit from the collective knowledge and evidence-based injury avoidance strategies shared by authors who have learned to master the art of skull base surgery.
From the latest vaccination evidence, recommendations, and protocols . . . to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. - Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. - Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. - Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. - Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
This book, Bacteriophages in health and disease, is an effort to provide an introduction to the breadth of roles that phages play or can play in our everyday lives. To capture this variety of phage roles in human conditions, both natural and applied, the book is divided into three parts. A brief introduction to various concepts and terminology associated with phages is provided in chapter 1. Part I (chapters 2-6) considers the role of phages in the natural state. That is, where phages are, how they contribute directly to disease, the underlying mechanism by which phages do this, and how they can contribute indirectly to disease, that is, to pathogen evolution. Part II (chapters 7-11) considers various phage-based technologies other than the use of whole phages to combat bacterial infections (i.e. besides phage therapy). This includes in particular the use of both modified and 'disembodied' phage parts. Phages thus can serve as carriers and delivery vehicles of DNA and also of other chemicals, including serving as vectors for either gene therapy or DNA vaccines. Part III (chapters 12-17) covers phage-based antibacterial strategies. It includes chapters on: phage translocation, safety and immunomodulation; phage therapy of wounds and related purulent infections; phage therapy of non-wound infections; phage-based enzybiotics; and phage-based control of bacterial pathogens in food. The final chapter of this book is targeted to would-be phage therapy experimentalists, one that considers, in light of phage properties, how phage therapy protocols may be developed in terms of the use of animal models of bacterial disease.
Although nuclear magnetic resonance is perhaps best known for its spectacular utility in medical tomography, its potential applicability to fields such as biology, materials science, and chemical physics is being increasingly recognized as laboratory NMR spectrometers are adapted to enable small scale imaging. This excellent introduction to the subject explores principles and common themes underlying two key variants of NMR microscopy, and provides many examples of their use. Methods discussed are not only important to fundamental biological and physical research, but have applications to a wide variety of industries, including those concerned with petrochemicals, polymers, biotechnology, food processing, and natural product processing. The wide range of scientists interested in NMR microscopy will want to own a copy of this book.
Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. - Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. - Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics - Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. - Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.
Enhance your surgical skills with Atlas of Oral and Maxillofacial Surgery, 2nd Edition! Written by respected international contributors and edited by OMS experts Paul Tiwana and Deepak Kademani, the new edition of this practical, comprehensive guide is divided into two volumes with eBook access included with the print purchase. It offers detailed, step-by-step instructions and more than 2,500 full-color illustrations that demonstrate how to plan for and perform oral and maxillofacial surgical procedures safely and efficiently. Comprehensive and expanded coverage addresses the broad scope of the specialty, ranging from the surgical anatomy of the head and neck to oral surgery, implant surgery, orthognathic and craniofacial surgery, cleft lip and palate, craniomaxillofacial trauma, head and neck oncology, reconstructive procedures, TMJ surgery, facial cosmetic surgery, obstructive sleep apnea, and more. - Comprehensive, consistent approach to OMS operative procedures offers practical guidance for the management of patients with oral and maxillofacial disorders, with each surgical procedure chapter approximately six to eight pages in length and covering the following topics: armamentarium, history of the procedure, indications for use of the procedure, limitations and contraindications, technique, alternate or modified technique, avoidance and management of intraoperative complications, and postoperative considerations. - More than 2,500 images include vibrant, modern medical illustrations and clinical photos that make up the heart of each surgical chapter and bring it to life visually. - Detailed, step-by-step approach shows how to perform OMS surgical procedures safely and efficiently. - Coverage of alternative and modified techniques addresses options beyond the standard techniques. - Expert, international contributors provide authoritative guidance on the OMS procedures they typically perform. - NEW! Two-volume extended edition is easier to navigate and includes extensive updates throughout. - NEW! More than 30 new chapters expand the coverage of implants, craniofacial surgery, and facial cosmetic surgery — plus an all-new section discusses obstructive sleep apnea (OSA). - NEW! An eBook version included only with print purchase allows you to access all the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
Now in its 7th edition, Auerbach's Wilderness Medicine continues to help you quickly and decisively manage medical emergencies encountered in any wilderness or other austere setting! World-renowned authority Dr. Paul Auerbach and 2 new associate editors have assembled a team of experts to offer proven, practical, visual guidance for effectively diagnosing and treating the full range of issues that can occur in situations where time and resources are scarce. This indispensable resource equips physicians, nurses, advanced practice providers, first responders, and rescuers with the essential knowledge and skills to effectively address and prevent injuries and illnesses – no matter where they happen! - Brand-new 2-volume format ensures all content is available in print and online to provide you easy access. - Face any medical challenge in the wilderness with expert guidance from hundreds of outstanding world experts edited by Dr. Auerbach and 2 new associate editors, Drs.Tracy Cushing and N. Stuart Harris - New and expanded chapters with hundreds of new photos and illustrative drawings help increase your visual understanding of the material - Acquire the knowledge and skills you need with revised chapters providing expanded discussions of high-altitude medicine, improvisation, technical rescue, telemedicine, ultrasound, and wilderness medicine education - Ten new chapters cover Acute High-Altitude Medicine and Pathophysiology; High Altitude and Pre-Existing Medical Conditions; Cycles, Snowmobiles, and other Wilderness Conveyances; Medical Wilderness Adventure Races (MedWAR); Canyoneering and Canyon Medicine; Evidence-Based Wilderness Medicine; National Park Service Medicine; Genomics and Personalized Wilderness Medicine; Forestry; and Earth Sciences - 30+ Expert Consult online videos cover survival tips, procedural demonstrations, and detailed explanations of diseases and incidents - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos, and references from the book on a variety of devices
Clinical Ultrasound has been thoroughly revised and updated by a brand new editorial team in order to incorporate the latest scanning technologies and their clinical applications in both adult and paediatric patients. With over 4,000 high-quality illustrations, the book covers the entire gamut of organ systems and body parts where this modality is useful. It provides the ultrasound practitioner with a comprehensive, authoritative guide to image diagnosis and interpretation. Colour is now incorporated extensively throughout this edition in order to reflect the advances in clinical Doppler, power Doppler, contrast agents. Each chapter now follows a consistent organizational structure and now contains numerous summary boxes and charts in order to make the diagnostic process practical and easy to follow. Covering all of the core knowledge, skills and experience as recommended by the Royal College of Radiologists, it provides the Fellow with a knowledge base sufficient to pass professional certification examinations and provides the practitioner with a quick reference on all currently available diagnostic and therapeutic ultrasound imaging procedures. - Individual chapters organized around common template therefore establishing a consistent diagnostic approach throughout the text and making the information easier to retrieve. - Access the full text online and download images via Expert Consult. - Three brand new editors and many new contributing authors bring a fresh perspective on the content. - Authoritative coverage of the most recent advances and latest developments in cutting edge technologies such as: colour Doppler, power Doppler, 3D and 4D applications, harmonic imaging, high intensity focused ultrasound (HIFU) microbubble contrast agents, interventional ultrasound , laparoscopic ultrasound brings this edition right up to date in terms of the changes in technology and the increasing capabilities/applications of ultrasound equipment. - New sections on musculoskeletal imaging. - Addition of coloured text, tables, and charts throughout will facilitate quick review and enhance comprehension.
Clinical Anesthesia, Seventh Edition covers the full spectrum of clinical options, providing insightful coverage of pharmacology, physiology, co-existing diseases, and surgical procedures. This classic book is unmatched for its clarity and depth of coverage. *This version does not support the video and update content that is included with the print edition. Key Features: • Formatted to comply with Kindle specifications for easy reading • Comprehensive and heavily illustrated • Full color throughout • Key Points begin each chapter and are labeled throughout the chapter where they are discussed at length • Key References are highlighted • Written and edited by acknowledged leaders in the field • New chapter on Anesthesia for Laparoscopic and Robotic Surgery Whether you’re brushing up on the basics, or preparing for a complicated case, the digital version will let you take the content wherever you go.
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. These phages played a unique role in early studies of molecular biology, the genetic code, translation, replication, suppression of mutations. Special attention is devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery, evolutionary and environmental studies. Included is an overview of the generation of novel vaccines, gene therapy vectors, drug delivery, and diagnostic tools exploring the role of RNA phage-derived products in the revolutionary progress of the protein tethering and bioimaging protocols. Key Features Presents the first full guide to single-stranded RNA phages Reviews the history of molecular biology summarizing the role RNA phages in the development of the life sciences Demonstrates how RNA phage-derived products have resulted in nanotechnological applications Presents an up-to-date account of the role played by RNA phages in evolutionary and environmental studies
Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination--from development to use in reducing disease. It also includes access to a companion Web site for more coverage.
Cryptography, in particular public-key cryptography, has emerged in the last 20 years as an important discipline that is not only the subject of an enormous amount of research, but provides the foundation for information security in many applications. Standards are emerging to meet the demands for cryptographic protection in most areas of data communications. Public-key cryptographic techniques are now in widespread use, especially in the financial services industry, in the public sector, and by individuals for their personal privacy, such as in electronic mail. This Handbook will serve as a valuable reference for the novice as well as for the expert who needs a wider scope of coverage within the area of cryptography. It is a necessary and timely guide for professionals who practice the art of cryptography. The Handbook of Applied Cryptography provides a treatment that is multifunctional: It serves as an introduction to the more practical aspects of both conventional and public-key cryptography It is a valuable source of the latest techniques and algorithms for the serious practitioner It provides an integrated treatment of the field, while still presenting each major topic as a self-contained unit It provides a mathematical treatment to accompany practical discussions It contains enough abstraction to be a valuable reference for theoreticians while containing enough detail to actually allow implementation of the algorithms discussed Now in its third printing, this is the definitive cryptography reference that the novice as well as experienced developers, designers, researchers, engineers, computer scientists, and mathematicians alike will use.
This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Paul Hruz, is devoted to HIV and Endocrine Disorders. Articles in this issue include: Dyslipidemia and cardiovascular risk in HIV infection; Changes in nutritional concerns in HIV/AIDS; HIV Lipodystrophy: Lessons learned about adipose tissue and metabolic disorders; Hypogonadism in the HIV infected male; Gonadal function and reproductive health in women with HIV; Osteopenia, osteoporosis, and fracture risk with HIV infection and treatment; HIV-associated calcium and vitamin D abnormalities; Alterations in pancreatic islet function in HIV; Insulin resistance, glucose intolerance, and diabetes in HIV; Thyroid abnormalities in HIV; HPA axis/adrenal pathology in HIV; and Endocrinopathies in HIV-infected children.
Major advances have been made in recent years in clarifying the molecular properties of the cytochrome P-450 system. These advances stem, in practical terms, from the generally recognized importance of cytochrome P-450 in the metabolism of drugs and in the bioactivation of xenobiotics to toxic products. The fascinating multiplicity and differential regulation of cytochrome P-450 isozymes, and their ability to catalyze extraordinarily difficult chemical transformations, have independently drawn many chemists and biochemists into the P-450 circle. Progress in the field, from a technical point of view, has been propelled by the de velopment of reliable procedures for the purification of membrane-bound enzymes, by the growing repertoire of molecular biological techniques, and by the development of chemical models that mimic the catalytic action of P-450. As a result, our understanding of the P-450 system is moving from the descriptive, pharmacological level into the tangible realm of atomic detail. The rapid progress and multidisciplinary character of the cytochrome P-450 field, which cuts across the lines that traditionally divide disciplines as diverse as inorganic chemistry and genetics, have created a need for an up-to-date evaluation of the advances that have been made. It is hoped that this book, with its molecular focus on the cytochrome P-450 system, will alleviate this need. The authors of the individual chapters have strived to emphasize recent results without sacrificing the background required to make their chapters comprehensible to informed nonspecialists.
The methods and thinking of economics permeate a large part of the IS discipline. Reciprocally, newly emerging research methods relying on the IT-enabled treatment of massive data aggregates feed economic research. As new and radical forms of IT innovation continue to energize electronic commerce, IS researchers face a daunting task in using existing empirical methods and tools to understand the threats, opportunities, risks, and rewards of these new techniques. This groundbreaking volume leads the way. It introduces new methodological approaches to data analysis as well as new techniques for collecting and cataloging transactional data. The ideas it presents have broad appeal and demonstrate what is possible when new techniques and new ways of thinking are brought to bear on complex research problems.
When every moment counts, count on Poisoning & Drug Overdose A Doody's Core Title for 2023! Speed is crucial when dealing with toxicologic and drug-related emergencies. Finding answers quickly is easier than ever with this streamlined eighth edition of Poisoning and Drug Overdose. This instant-answer guide provides the critical information needed to diagnose and manage drug-related emergencies and chemical exposures. Updated with newly released drugs and new information on existing drugs, the guide covers initial emergency management, including treatment of coma, seizures and hypotension; physical and laboratory diagnosis; and methods of decontamination and enhanced elimination of poisons. Poisoning and Drug Overdose, Eighth Edition is divided into four sections: Section I. Provides a stepwise approach to the evaluation and treatment of coma, seizures, shock, and other complications of poisoning and the proper use of gastric decontamination and dialysis procedures. Section II. Lists specific poisons and drugs, as well as the pathophysiology, toxic dose and level, clinical presentation, diagnosis, and specific treatment associated with each substance. Section III. Covers descriptions of therapeutic drugs and antidotes, including pharmacology indications, adverse effects, drug interactions, and recommended dosage. Section IV. Describes the approach to hazardous materials incidents; the evaluation of occupational exposures; and the toxic effects, physical properties, and workplace limits for over 500 common industrial chemicals. Poisoning and Drug Overdose, Eighth Edition is enhanced by numerous tables and charts, as well as a user-friendly index. This trusted resource has consistently been relied upon by front line professionals responding to drug-related emergencies and chemical exposures.
Pt. 1. Lead in the human environment -- pt. 2. Lead exposure in human populations -- pt. 3. Lead toxicity in humans -- pt. 4. Human health risk assessment -- pt. 5. Regulatory approaches to control.
The instant-answer guide clinicians turn to first for on-the-spot treatment of poisoning and drug overdose emergencies A Doody’s Core Title for 2021! “...a great addition to any emergency department library when rapid reference is needed to treat and diagnose the poisoned patient.” -- Annals of Emergency Medicine (Reviewing previous edition) Designed to be used during toxicologic emergencies where every moment counts, Poisoning & Drug Overdose, Seventh Edition delivers critical information on the effective diagnosis and treatment of drug-related emergencies and chemical exposures. This at-a-glance guide is enhanced by detailed tables and charts, extensive cross referencing, and a comprehensive index featuring generic, chemical, and brand names. Poisoning & Drug Overdose is divided into four sections: Section 1 leads readers through initial emergency management, including treatment of coma, hypotension, and other common complications; physical and laboratory diagnosis; and methods of decontamination and enhanced elimination of poisons Section II provides detailed information on 150 common drugs and poisons Section III describes the use and side effects of 60 antidotes and therapeutic drugs Section IV describes the medical management of chemical spills and occupations chemical exposures and includes a table of more than 500 industrial chemicals • Thoroughly updated to reflect newly released drugs, new information on existing drugs, and coverage of the latest black box (and other) warnings • NEW to this edition: information on drug-environmental exposure interactions, coverage of environmental toxins such as mold, asbestos, and others
Progress in Drug Research is a prestigious book series which provides extensive expert-written reviews on a wide spectrum of highly topical areas in current pharmaceutical and pharmacological research. It serves as an important source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines.
Findings from the field of evolutionary biology are yielding dramatic insights for health scientists, especially those involved in the fight against infectious diseases. This book is the first in-depth presentation of these insights. In detailing why the pathogens that cause malaria, smallpox, tuberculosis, and AIDS have their special kinds of deadliness, the book shows how efforts to control virtually all diseases would benefit from a more thorough application of evolutionary principles. When viewed from a Darwinian perspective, a pathogen is not simply a disease-causing agent, it is a self-replicating organism driven by evolutionary pressures to pass on as many copies of itself as possible. In this context, so-called "cultural vectors"--those aspects of human behavior and the human environment that allow spread of disease from immobilized people--become more important than ever. Interventions to control diseases don't simply hinder their spread but can cause pathogens and the diseases they engender to evolve into more benign forms. In fact, the union of health science with evolutionary biology offers an entirely new dimension to policy making, as the possibility of determining the future course of many diseases becomes a reality. By presenting the first detailed explanation of an evolutionary perspective on infectious disease, the author has achieved a genuine milestone in the synthesis of health science, epidemiology, and evolutionary biology. Written in a clear, accessible style, it is intended for a wide readership among professionals in these fields and general readers interested in science and health.
During the past two decades, the world scientific community has witnessed major achievements in our understanding of the pathogenesis of HIV infection of the nervous system and HIV-Associated Dementia (HAD). Despite these giant gains, nervous system involvement during AIDS remains a relentlessly progressive disease with a deadly fate in many cases. This book on NeuroAIDS provides a unique resource for both general neurologists as well as basic neuroscientists with profound interests for research on NeuroAIDS. This book has special emphasis on the mechanisms of disease development and progression of HIV-infected patients with NeuroAIDS. The contributors have provided the readers with comprehensive reviews on clinical manifestations of HAD, mechanisms of HIV entry into the central nervous system, the role of cytokines and chemokines in pathogenesis of NeuroAIDS, drug abuse and NeuroAIDS, virus load in HAD, allostasis in HIV and AIDS, stroke in AIDS patients, and neuroimaging of HIV infection of the central nervous system. In addition, there are chapters on Varicella Zoster virus infection of HIV-seropositive and AIDS patients, as well as the molecular basis for opioids and AIDS virus interactions.
Tibetan Literature addresses the immense variety of Tibet's literary heritage. An introductory essay by the editors attempts to assess the overall nature of 'literature' in Tibet and to understand some of the ways in which it may be analyzed into genres. The remainder of the book contains articles by nearly thirty scholars from America, Europe, and Asia—each of whom addresses an important genre of Tibetan literature. These articles are distributed among eight major rubrics: two on history and biography, six on canonical and quasi-canonical texts, four on philosophical literature, four on literature on the paths, four on ritual, four on literary arts, four on non-literary arts and sciences, and two on guidebooks and reference works.
In 2016 Current Topics in Developmental Biology (CTDB) will celebrate its 50th or "golden anniversary. To commemorate the founding of CTDB by Aron Moscona (1921-2009) and Alberto Monroy (1913-1986) in 1966, a two-volume set of CTDB (volumes 116 and 117), entitled Essays on Development, will be published by Academic Press/Elsevier in early 2016. The volumes are edited by Paul M. Wassarman, series editor of CTDB, and include contributions from dozens of outstanding developmental biologists from around the world. Overall, the essays provide critical reviews and discussion of developmental processes for a variety of model organisms. Many essays relate the history of a particular area of research, others personal experiences in research, and some are quite philosophical. Essays on Development provides a window onto the rich landscape of contemporary research in developmental biology and should be useful to both students and investigators for years to come. - Covers the area of developmental processes for a variety of model organisms - International board of authors - Part of two 50th Anniversary volumes proving a comprehensive set of reviews edited by Serial Editor Paul M. Wassarman
This compact and innovative book tackles one of the central issues in drug policy: the lack of a coherent conceptual structure for thinking about drugs. Drugs generally fall into one of seven categories: prescription, over the counter, alternative medicine, common-use drugs like alcohol, tobacco and caffeine; religious-use, sports enhancement; and of course illegal street drugs like cocaine and marijuana. Our thinking and policies varies wildly from one to the other, with inconsistencies that derive more from cultural and social values than from medical or scientific facts. Penalties exist for steroid use, while herbal remedies or cold medication are legal. Native Americans may legally use peyote, but others may not. Penalties may vary for using different forms of the same drug, such as crack vs. powder cocaine. Herbal remedies are unregulated by the FDA; but medical marijuana is illegal in most states. Battin and her contributors lay a foundation for a wiser drug policy by promoting consistency and coherency in the discussion of drug issues and by encouraging a unique dialogue across disciplines. The contributors are an interdisciplinary group of scholars mostly based at the University of Utah, and include a pharmacologist, a psychiatrist, a toxicologist, a trial court judge, a law professor, an attorney, a diatary specialist, a physician, a health expert on substance abuse, and Battin herself who is a philosopher. They consider questions like the historical development of current policy and the rationales for it; scientific views on how drugs actually cause harm; how to define the key notions of harm and addiction; and ways in which drug policy can be made more consistent. They conclude with an examination of the implications of a consistent policy for various disciplines and society generally. The book is written accessibly with little need for expert knowledge, and will appeal to a diverse audience of philosophers, bioethicists, clinicians, policy makers, law enforcement, legal scholars and practitioners, social workers, and general readers, as well as to students in areas like pharmacy, medicine, law, nursing, sociology, social work, psychology, and bioethics.
Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who's who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you'll need to offer your patients the best possible care. - Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. - Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians. - Diagnose AIDS manifestations confidently by comparing them to full-color clinical images. - Improve patient outcomes with the latest findings on the management of AIDS as a chronic illness. - Efficiently review essential data through numerous at-a-glance tables. - Get the most relevant information available on pediatric HIV and AIDS issues; anti-retroviral drugs, including integrase inhibitors; and the use of second- and third-line anti-retroviral drugs in resource-poor settings. - Stay current on the latest actionable information, such as using antiretroviral therapy in patients with tuberculosis and drug-resistant tuberculosis; antiretroviral therapy; immune reconstitution inflammatory syndromes (IRIS); and implementation of the HPV vaccine.
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