This book introduces a new research direction in set theory: the study of models of set theory with respect to their extensional overlap or disagreement. In Part I, the method is applied to isolate new distinctions between Borel equivalence relations. Part II contains applications to independence results in Zermelo–Fraenkel set theory without Axiom of Choice. The method makes it possible to classify in great detail various paradoxical objects obtained using the Axiom of Choice; the classifying criterion is a ZF-provable implication between the existence of such objects. The book considers a broad spectrum of objects from analysis, algebra, and combinatorics: ultrafilters, Hamel bases, transcendence bases, colorings of Borel graphs, discontinuous homomorphisms between Polish groups, and many more. The topic is nearly inexhaustible in its variety, and many directions invite further investigation.
This is an expository account of work on strong forms of the Axiom of Determinacy (AD) by a group of set theorists in Southern California, in particular by W. Hugh Woodin. The first half of the book reviews necessary background material, including the Moschovakis Coding Lemma, the existence of strong partition cardinals, and the analysis of pointclasses in models of determinacy. The second half of the book introduces Woodin's axiom system $mathrm{AD}^{+}$ and presents his initial analysis of these axioms. These results include the consistency of $mathrm{AD}^{+}$ from the consistency of AD, and its local character and initial motivation. Proofs are given of fundamental results by Woodin, Martin, and Becker on the relationships among AD, $mathrm{AD}^{+}$, the Axiom of Real Determinacy, and the Suslin property. Many of these results are proved in print here for the first time. The book briefly discusses later work and fundamental questions which remain open. The study of models of $mathrm{AD}^{+}$ is an active area of contemporary research in set theory. The presentation is aimed at readers with a background in basic set theory, including forcing and ultrapowers. Some familiarity with classical results on regularity properties for sets of reals under AD is also expected.
Over half of the world's population is afflicted with some form of chronic or degenerative illness. Heart disease, autoimmune disease, diabetes, neurological conditions, cancer, Lyme disease--the list goes on. The conventional, allopathic, treat-the-symptom-with-pharmaceutical-drugs model is rapidly falling out of favor as patients are searching for nontoxic, advanced prevention and healing modalities that actually work. Bioregulatory Medicine introduces a model that has proven effective for decades in other more forward-thinking developed countries, including Switzerland and Germany. Our bodies have many bioregulating systems, including the cardiovascular, digestive, neurological, respiratory, endocrine, and so on. Bioregulatory medicine is a comprehensive and holistic approach to health that advocates the use of natural healing methods to support and restore the body's intrinsic self-regulating and self-healing mechanisms, as opposed to simply treating symptoms with integrative therapies. Bioregulatory medicine is about discovering the root cause of disease and takes into account the entire person from a genetic, epigenetic, metabolic, energetic, and emotional point of view. So while patients may have the same disease or prognosis, the manifestation of illness is entirely bioindividual and must be treated and prevented on an individual level. Bioregulatory Medicine addresses the four pillars of health--drainage and detox, diet, mind-body medicine, and oral health--using a sophisticated synthesis of the very best natural medicine with modern advances in technology. In addition to identifying the cause of disease, bioregulatory medicine promotes disease prevention and early intervention of illness through noninvasive diagnostics and treatments, and incorporates the use of over 100 different non-toxic diagnostics and treatments from around the world. Forward-thinking patients and integrative practitioners will find Bioregulatory Medicine invaluable as they seek to deepen their understanding of the body's many regulating systems and innate ability to heal itself.
This book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter’s arrangement. The term "VLP" is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions. Key Features Presents the first full guide to the VLP nanotechnology, classified by current viral taxonomy Outlines specific structural properties and interconnection of the virions and VLPs Explains generation and characteristics of VLPs produced by various expression systems Offers up-to-date summary of VLPs designed as vaccines and delivery tools Unveils interconnection of VLPs with novel organic and inorganic nanomaterials
Paul Maharg presents a critical inquiry into the identity and possibilities of legal education, and an exploration of transformational alternatives to our current theories and practices of teaching and learning the law. His work takes the view that bodies of interdisciplinary theory and knowledge of the history of legal education are important to all stages of legal education. He also argues that new learning designs - such as transactional learning - need to be developed to help students, educators and lawyers deal with the transitions and challenges facing them now and in the foreseeable future. Throughout, discussions of theory are spliced with case studies of academic and professional legal learning, particularly in the field of technology-enhanced learning. The content of the book will be updated in a community of practice wiki at http://www.transforming.org.uk, which will also allow readers to comment and expand on the book's final chapter.
In coastal seas, from the tropics to the poles, seaweeds supply the energy required to support diverse coastal marine life and provide habitat for invertebrates and fish. Retaining the highly successful approach and structure of the first edition, this is a synthesis of the role of seaweeds in underpinning the functioning of coastal ecosystems worldwide. It has been fully updated to cover the major developments of the past twenty years, including current research on the endosymbiotic origin of algae, molecular biology including 'omics', chemical ecology, invasive seaweeds, photobiology and stress physiology. In addition to exploring the processes by which seaweeds, as individuals and communities, interact with their biotic and abiotic environment, the book presents exciting new research on how seaweeds respond to local and global environmental change. It remains an invaluable resource for students and provides an entry into the scientific literature of a wide range of topics.
The stationary tower is an important method in modern set theory, invented by Hugh Woodin in the 1980s. It is a means of constructing generic elementary embeddings and can be applied to produce a variety of useful forcing effects. Hugh Woodin is a leading figure in modern set theory, having made many deep and lasting contributions to the field, in particular to descriptive set theory and large cardinals. This book is the first detailed treatment of his method of the stationary towerthat is generally accessible to graduate students in mathematical logic. By giving complete proofs of all the main theorems and discussing them in context, it is intended that the book will become the standard reference on the stationary tower and its applications to descriptive set theory. Thefirst two chapters are taken from a graduate course Woodin taught at Berkeley. The concluding theorem in the course was that large cardinals imply that all sets of reals in the smallest model of set theory (without choice) containing the reals are Lebesgue measurable. Additional sections include a proof (using the stationary tower) of Woodin's theorem that, with large cardinals, the Continuum Hypothesis settles all questions of the same complexity as well as some of Woodin's applications of thestationary tower to the studies of absoluteness and determinacy. The book is suitable for a graduate course that assumes some familiarity with forcing, constructibility, and ultrapowers. It is also recommended for researchers interested in logic, set theory, and forcing.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Provide continuous, comprehensive care of patients throughout their lifetimes with this evidence-based guide An easy-to-use guide to the diagnosis, treatment, and management of the full range of clinical conditions seen in primary care NEW content includes coverage of genetics and precision medicine use in family medicine, telehealth in family medicine, CTE and sports injuries, Zika, the opioid epidemic, Hepatitis C, expansion of the HIV section, veteran's health and PTSD, and more The leading resource for USMLE Step 3 review, board certification and maintenance or recertification Essential for primary care trainees, practicing physicians, advanced practice nurses, and physician assistants Features Organized according to the developmental lifespan, beginning with childhood and adolescence and progressing through adulthood and senior years Evidence-based recommendations Conservative and pharmacologic therapies Complementary and alternative therapies when relevant Suggestions for collaborations with other healthcare providers Attention to the mental and behavioral health of patients as solitary as well as comorbid conditions Recognition of impact of illness on the family Patient education information End-of-life issues
3 books illuminate the cutting edge medical research that could save your life Right now, science is transforming what we know about preserving and improving human health. These three extraordinary books take you to the cutting edge of emerging science, presenting new findings that might someday save your life. In Antibiotic Resistance: Understanding and Responding to an Emerging Crisis, Karl S. Drlica and David S. Perlin presents a thorough and authoritative overview of the growing resistance of pathogenic bacteria to antibiotics, and what this means to our ability to control and treat infectious diseases. The authors answer crucial questions such as: What is resistance? How does it emerge? How do common human activities promote resistance? What can we do about it? How can we strengthen our defenses against resistance, minimize our risks, extend the effectiveness of current antibiotics, and find new ones faster? Next, in Chips, Clones, and Living Beyond 100: How Far Will the Biosciences Take Us?, Paul and Joyce A. Schoemaker tour the remarkable field of biosciences as it stands today, and preview the directions and innovations that are most likely to emerge in the coming years. They offer a clear, non-technical overview of crucial current developments that are likely to have enormous impact, addressing issues ranging from increased human longevity to global warming, bio-warfare to personalized medicine. Along the way, they illuminate each of the exciting technologies and hot-button issues associated with contemporary biotechnology - including stem cells, cloning, probiotics, DNA microarrays, proteomics, gene therapy, and more. Finally, in It Takes a Genome, Greg Gibson posits a revolutionary new hypothesis: our genome is out of equilibrium, both with itself and its environment. Our bodies weren’t designed to subsist on fat and sugary foods; our immune systems aren’t designed for today’s clean, bland environments; our minds aren’t designed to process hard-edged, artificial electronic inputs from dawn ‘til midnight. That, says Gibson, is why so many of us suffer from chronic diseases that barely touched our ancestors. Gibson reveals the stunningly complex ways genes cooperate and interact; illuminates the genetic “mismatches” that lead to cancer, diabetes, inflammatory and infectious diseases, AIDS, depression, and senility; and considers surprising new evidence for genetic variations in human psychology. From world-renowned leaders and experts, including Karl S. Drlica, David S. Perlin, Paul J. H. Schoemaker, Joyce A. Schoemaker, and Greg Gibson
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