One of the best novelists since Jane Austen."—Philadelphia Inquirer This novel is a powerful successor to Testimonies, Patrick O'Brian's first novel written for adults. It is set in that corner of France that became O'Brian's adopted home, where the long, dark wall of the Pyrenees runs headlong to meet the Mediterranean. Alain Roig returns to Saint-Féliu after years in the East and finds his family in crisis. His dour, middle-aged cousin Xavier, the mayor and most powerful citizen of the town, has fallen in love and plans to marry Madeleine, the young daughter of the local grocer. The Roig family property is threatened by this union, and Madeleine's relatives object on different grounds. Xavier is a tragic figure, damned by what he perceives as a lack of feeling; Madeleine is to be his salvation. Unfortunately she does not return his affection, and, as the feasts and harvest festivals of Saint-Féliu are played out, she finds herself falling in love with Alain.
Evidence-Based Practice of Critical Care, 2nd Edition, presents objective data and expert guidance on managing critically ill patients in unique question-based chapters that focus on best practices. Now thoroughly updated by Drs. Clifford S. Deutschman, Patrick J. Neligan, and nearly 200 critical-care experts, this highly regarded title remains the only book of its kind that provides a comprehensive framework for translating evidence into practice, making it a valuable resource for both residents and practitioners. Tap into the expertise of nearly 200 critical-care experts who discuss the wide variety of clinical options in critical care, examine the relevant research, and provide recommendations based on a thorough analysis of available evidence. Think through each question in a logical, efficient manner, using a practical, consistent approach to available management options and guidelines. Find the information you need quickly with tables that summarize the available literature and recommended clinical approaches. Navigate a full range of challenges from routine care to complicated and special situations. Stay up to date with new issues and controversies such as the redefinition of sepsis . changing approaches to fluid administration . immune suppression in sepsis . monitoring the microcirculation . the long-term sequelae of critical illness . minimizing ventilator associated lung injury . the benefits of evidence-based medicine management guidelines . rapid response teams . and more. Benefit from all-new sections covering persistent critical illness and the role of advanced practice nurses and physician assistants in the ICU.
A collaboration of the American College of Physicians and the Clerkship Directors in Internal Medicine, this new edition was written by authors who helped design the internal medicine curriculum and who are actively involved in teaching students on the Internal Medicine clerkship. Prepare for internal medicine clinical rounds and the end-of-rotation exam with the fully revised and updated Internal Medicine Essentials for Clerkship Students 2! This new edition is organized around the major training areas included in the nationally recognized Core Medicine Clerkship Curriculum Guide
For more than two centuries the idea of the nation-state has been widespread. The expression is now widely used and is even to be unavoidable. The 'nation-state' implies that the population of a state should be homogenous in terms of language, religion, and ethnicity; the nation and the state should coincide. However history demonstrates that there never has been, and there never will be, a nation-state. Human diversity is manifest in states of all sizes, locations, and origins. This wide-ranging book argues that there should be no regret in the recognition of this empirical reality, since the notion of a nation-state has been the justification for some of the worst atrocities in human history. Since the nation-state is impossible, all states are cosmopolitan in character. They are cosmopolitan regardless of the language of their constitutions or official teaching and regardless of the extent to which they officially recognize their own diversity. The most successful states are those which are most successful in their own forms of cosmopolitanism. Cosmopolitan ways are infinitely varied, however, and must be sought in the intricate workings of individual states. The cosmopolitan character of states is necessarily reflected in their law. The main instruments of legal cosmopolitanism have been those of common laws, constitutionalism, and what is best described as institutional cosmopolitanism. The relative importance of these legal instruments has changed over time but all three have been constantly operative, even in times of attempted national and territorial closure. All three remain present in the contemporary cosmopolitan state, understood in terms of cosmopolitan citizens, cosmopolitan sources and cosmopolitan thought. The cosmopolitan state is, moreover, the only appropriate conceptualization of the state in a time of globalization. This book outlines the subtlety of the law of cosmopolitan states, law which has survived through periods of nationalism and which provides the working methods for the reconciliation of diverse populations. Combining law, history, political science, political philosophy, international relations, and the new logics, it demonstrates that the idea of the nation-state has failed and should yield to an understanding of the state as necessarily cosmopolitan in character. This will be invaluable reading to all those interested in constitutional law, international law, and political theory.
Evidence-Based Practice of Critical Care, 2nd Edition, presents objective data and expert guidance on managing critically ill patients in unique question-based chapters that focus on best practices. Now thoroughly updated by Drs. Clifford S. Deutschman, Patrick J. Neligan, and nearly 200 critical-care experts, this highly regarded title remains the only book of its kind that provides a comprehensive framework for translating evidence into practice, making it a valuable resource for both residents and practitioners. Tap into the expertise of nearly 200 critical-care experts who discuss the wide variety of clinical options in critical care, examine the relevant research, and provide recommendations based on a thorough analysis of available evidence. Think through each question in a logical, efficient manner, using a practical, consistent approach to available management options and guidelines. Find the information you need quickly with tables that summarize the available literature and recommended clinical approaches. Navigate a full range of challenges from routine care to complicated and special situations. Stay up to date with new issues and controversies such as the redefinition of sepsis • changing approaches to fluid administration • immune suppression in sepsis • monitoring the microcirculation • the long-term sequelae of critical illness • minimizing ventilator associated lung injury • the benefits of evidence-based medicine management guidelines • rapid response teams • and more. Benefit from all-new sections covering persistent critical illness and the role of advanced practice nurses and physician assistants in the ICU.
The ultimate resource for USMLE Step 3 preparation! This addition to the best-selling medical review series supplies key information about the USMLE Step 3 exam, evaluates study tools, and reviews tested patient-management information. Provides residents with essential strategies for the computer-administered test, high-yield information, and includes a section of mini-cases to prepare examinees for the CCS portion of the exam.
This fourth edition of Medicine at a Glance, the leading title in the best-selling at a Glance series, provides an unparalleled overview of the study of medicine, closely following the core medical curriculum. Ideal for medical students, Foundation programme doctors and those training in the allied health professions, Medicine at a Glance presents vital information on clinical presentations, diseases, and treatments in every major medical specialty, from cardiology to dermatology. Medicine at a Glance: • Has been fully revised to reflect essential clinical and curriculum updates. • Contains brand new material in key areas such as imaging, women’s health, communication and data interpretation. • Features a brand new, clearer text design, in the trusted at a Glance double-page spread style, in full-colour throughout. • Is the ideal, practical companion to clinical attachments, available in a range of digital formats for on-the-go study and revision. • Includes a companion website at www.ataglanceseries.com/medicine featuring interactive Multiple Choice Questions (MCQs), interactive flashcards with show/hide labels, and tables of normal values This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.
The Oxford American Handbooks of Medicine, now available in PDA format, each offer a short but comprehensive overview of an entire specialty featuring instant access to guidance on the conditions that are most likely to be encountered. Precise and prescriptive, the handbooks offer up-to-date advice on examination, investigations, common procedures, and in-patient care. Written by leading American practitioners, these PDAs will be invaluable resources for students, residents, and practitioners. These PDA versions enable enhanced, multi-layered access to the entire text, illustrations, and tables. Other features include fast access available via the key word search, and a facility for book marking and annotating the text. It is suitable for Palm and Windows Mobile.
This book is the third volume of Advanced Dairy Chemistry, which should be regarded as the second edition of Developments in Dairy Chemistry. Volume 1 of the series, Milk Proteins, was published in 1992 and Volume 2, Milk Lipids, in 1994. Volume 3, on lactose, water, salts and vitamins, essentially updates Volume 3 of Developments in Dairy Chemistry but with some important changes. Five of the eleven chapters are devoted to lactose (its physico-chemical properties, chemical modification, enzymatic modification and nutritional aspects), two chapters are devoted to milk salts (physico-chemical and nutritional aspects), one to vitamins and one to overview the flavour of dairy products. Two topics covered in the first editions (enzymes and other biologically active proteins) were transferred to Volume 1 of Advanced Dairy Chemistry and two new topics (water and physico chemical properties of milk) have been introduced. Although the constituents covered in this volume are commercially less important than proteins and lipids covered in Volumes 1 and 2, they are critically important from a nutritional viewpoint, especially vitamins and minerals, and to the quality and stability of milk and dairy products, especially flavour, milk salts and water. Lactose, the principal constituent of the solids of bovine milk, has long been regarded as essentially worthless and in many cases problematic from the nutritional and techno logical viewpoints; however, recent research has created several new possi bilities for the utilization of lactose.
This highly accessible and engaging introduction to IP law encourages readers to critically evaluate the ownership of intangible goods. The rigorous pedagogy, featuring many real-world cases, both historical and up-to-date, full colour images, discussion exercises, end-of-chapter questions and activities, allows readers to engage fully with the philosophical concepts foundational of the subject, while also enabling them to independently analyse key cases, texts and materials relevant to IP law in the contemporary world. This innovative textbook, written by one of the leading authorities on the subject, is the ideal route to a full understanding of copyright, patents, designs, trade marks, passing off, remedies and litigation for undergraduate and beginning graduate students in IP law.
On Rabbit Ridge is a story of a man recalling his childhood on the Menominee Indian Reservation in Northern Wisconsin. Watching his Grandmother heal people and helping his Grandfather grow food, make toys and help his community is anyway he could. Living off the land and overcoming the harsh times his Grandparents taught him life lessons he will never forget. Family is everything!
Acclaimed for its unsurpassed readability and manageable scope, Ashcraft’s Pediatric Surgery presents authoritative, practical guidance on treating the entire range of general surgical and urological problems in infants, children, and adolescents. State-of-the-art, expert coverage equips you to implement all the latest approaches and achieve optimal outcomes for all of your patients. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Make the most effective use of today’s best open and minimally invasive techniques, including single-site umbilical laparoscopic surgery, with guidance from internationally recognized experts in the field. Focus on evidence-based treatments and outcomes to apply today’s best practices. Stay current with timely topics thanks to brand-new chapters on Choledochal Cyst and Gallbladder Disease, Tissue Engineering, and Ethics in Pediatric Surgery, plus comprehensive updates throughout. Hone and expand your surgical skills by watching videos of minimally invasive procedures for recto urethral fistula, biliary atresia, laparoscopic splenectomy, uterine horn, and more. Grasp the visual nuances of surgery from over 1,000 images depicting today’s best surgical practices.
This book is about the mental lexicon and opens an understanding of this aspect of human cognition. The mental lexicon is still a central topic in psycholinguistics and, more generally speaking, in cognitive science. Is it possible to define what is intended by the expression "mental lexicon", a concept coined by Oldfield as early as 1966? Are the terms that the authors have at their disposal still sufficient to discuss this hypothesised mental entity -- the mental lexicon -- which is intended to cover many different aspects of words? The authors propose as a working definition that the mental lexicon corresponds to the mental repository of all representations that are intrinsically related to words. This book extends its research in psycholinguistics and focuses on the word.
Reprint of the original, first published in 1875. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
Known for its readability, portability, and global perspectives, Holcomb and Ashcraft's Pediatric Surgery remains the most comprehensive, up-to-date, single-volume text in its field. As technology and techniques continue to evolve, the 7th Edition provides state-of-the-art coverage—both in print and on video—of the full range of general surgical and urological problems in infants, children, and adolescents, equipping you to achieve optimal outcomes for every patient. - Provides authoritative, practical coverage to help you implement today's best evidence-based open and minimally invasive techniques, with guidance from internationally recognized experts in the field. - Features more than 1,000 high-quality images depicting the visual nuances of surgery for the full range of pediatric and urologic conditions you're likely to see. - Delivers comprehensive updates throughout including the latest advances in managing Inguinal Hernias and Hydroceles; Imperforate Anus and Cloacal Malformations; Hirschsprung Disease; Duodenal and Intestinal Atresia and Stenosis; Esophageal Atresia; and more. - Offers access to more than 50 videos that help you improve and refine your surgical skills. New videos cover Fetal Endoluminal Tracheal Occlusion (FETO); Laparoscopic Inguinal Hernia Repair; Robotic Extravesical Ureteral Reimplantation; Laparoscopic Management of Ovarian Torsion; and Laparoscopic Sleeve Gastrectomy. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. - Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections - Bridges the gap between the basic science and the important medical applications of this technology - Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering - Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs - Arms the reader with the cutting-edge information needed to stay abreast of this developing field
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