The tenth installment in the beloved, epic Aubrey/Maturin series and inspiration for the major motion picture starring Russell Crowe. The War of 1812 continues, and Captain Jack Aubrey sets course for Cape Horn on a mission after his own heart: intercepting a powerful American frigate outward bound to wreak havoc with the British whaling trade. Meanwhile, Stephen Maturin has a mission of his own in the world of secret intelligence and comes face to face with the harsh realities for women of the age. Disaster in various guises awaits them in the Great South Sea and in the far reaches of the Pacific—typhoons, castaways, shipwrecks, an ill-fated affair, murder, and criminal insanity—as well as a bold rescue by a crew of seafaring female warriors.
This book covers important biological, immunological, and molecular information essential for understanding the rationale and results of experiments and clinical observations on cell-cell and cell substrate adhesion; hydrolytic activities, cell motility; immunological and other host elements of the host-tumor ecosystem (at different sites of the metastic process); genetic and epigenetic elements of the acquisition and the expression of invasive phenotypes. 38 tables and 60 computer-drawn figures provide comprehensive overviews, and a methodological chapter emphasizing the differences and similarities between assays and their relevance for natural situations has also been included. Clinical and experimental cancer researchers, as well as as post-graduate students interested in cancer research, will find this book to be an indispensable reference resource.
Acclaimed for its unsurpassed readability and manageable scope, Ashcraft’s Pediatric Surgery presents authoritative, practical guidance on treating the entire range of general surgical and urological problems in infants, children, and adolescents. State-of-the-art, expert coverage equips you to implement all the latest approaches and achieve optimal outcomes for all of your patients. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Make the most effective use of today’s best open and minimally invasive techniques, including single-site umbilical laparoscopic surgery, with guidance from internationally recognized experts in the field. Focus on evidence-based treatments and outcomes to apply today’s best practices. Stay current with timely topics thanks to brand-new chapters on Choledochal Cyst and Gallbladder Disease, Tissue Engineering, and Ethics in Pediatric Surgery, plus comprehensive updates throughout. Hone and expand your surgical skills by watching videos of minimally invasive procedures for recto urethral fistula, biliary atresia, laparoscopic splenectomy, uterine horn, and more. Grasp the visual nuances of surgery from over 1,000 images depicting today’s best surgical practices.
Known for its readability, portability, and global perspectives, Holcomb and Ashcraft's Pediatric Surgery remains the most comprehensive, up-to-date, single-volume text in its field. As technology and techniques continue to evolve, the 7th Edition provides state-of-the-art coverage—both in print and on video—of the full range of general surgical and urological problems in infants, children, and adolescents, equipping you to achieve optimal outcomes for every patient. - Provides authoritative, practical coverage to help you implement today's best evidence-based open and minimally invasive techniques, with guidance from internationally recognized experts in the field. - Features more than 1,000 high-quality images depicting the visual nuances of surgery for the full range of pediatric and urologic conditions you're likely to see. - Delivers comprehensive updates throughout including the latest advances in managing Inguinal Hernias and Hydroceles; Imperforate Anus and Cloacal Malformations; Hirschsprung Disease; Duodenal and Intestinal Atresia and Stenosis; Esophageal Atresia; and more. - Offers access to more than 50 videos that help you improve and refine your surgical skills. New videos cover Fetal Endoluminal Tracheal Occlusion (FETO); Laparoscopic Inguinal Hernia Repair; Robotic Extravesical Ureteral Reimplantation; Laparoscopic Management of Ovarian Torsion; and Laparoscopic Sleeve Gastrectomy. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
Patrick O'Brian's Aubrey-Maturin tales are widely acknowledged to be the greatest series of historical novels ever written. All eighteen books are being re-issued in hardback by HarperCollins with stunning new jackets to coincide with a new film based on the adventures and to introduce these modern classics to a new generation. It is still the War of 1812. Patrick O'Brian takes his hero Jack Aubrey and his tetchy, sardonic friend Stephen Maturin on a voyage as fascinating as anything he has ever written. They set course across the South Atlantic to intercept a powerful American frigate outward bound to play havoc with the British whaling trade. If they do not come up with her before she rounds the Horn, they must follow her into the Great South Sea and as far across the Pacific as she may lead them. It is a commission after Jack's own heart. Maturin has fish of his own to fry in the world of secret intelligence. Aubrey has to cope with a succession of disasters - men overboard, castaways, encounters with savages, storms, typhoons, groundings, shipwrecks, to say nothing of murder and criminal insanity. That the enemy is in fact faithfully dealt with, no one who has the honour of Captain Aubrey's acquaintance can take leave to doubt.
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