Presents statistical methodologies for analyzing common types of data from method comparison experiments and illustrates their applications through detailed case studies Measuring Agreement: Models, Methods, and Applications features statistical evaluation of agreement between two or more methods of measurement of a variable with a primary focus on continuous data. The authors view the analysis of method comparison data as a two-step procedure where an adequate model for the data is found, and then inferential techniques are applied for appropriate functions of parameters of the model. The presentation is accessible to a wide audience and provides the necessary technical details and references. In addition, the authors present chapter-length explorations of data from paired measurements designs, repeated measurements designs, and multiple methods; data with covariates; and heteroscedastic, longitudinal, and categorical data. The book also: • Strikes a balance between theory and applications • Presents parametric as well as nonparametric methodologies • Provides a concise introduction to Cohen’s kappa coefficient and other measures of agreement for binary and categorical data • Discusses sample size determination for trials on measuring agreement • Contains real-world case studies and exercises throughout • Provides a supplemental website containing the related datasets and R code Measuring Agreement: Models, Methods, and Applications is a resource for statisticians and biostatisticians engaged in data analysis, consultancy, and methodological research. It is a reference for clinical chemists, ecologists, and biomedical and other scientists who deal with development and validation of measurement methods. This book can also serve as a graduate-level text for students in statistics and biostatistics.
This book focusses on the spacer engineering aspects of novel MOS-based device–circuit co-design in sub-20nm technology node, its process complexity, variability, and reliability issues. It comprehensively explores the FinFET/tri-gate architectures with their circuit/SRAM suitability and tolerance to random statistical variations.
How long will you wait for the love of your life? And how long will you actually endure the pain that comes from waiting for someone for an age? How long will you hold on to the trust in love? And how long will you actually believe in the smiles that love brings in some lonesome dark nights when you are thinking of nothing and nobody but your love! How long will you be able to believe that whatever happens, it happens for good? And how long will you be in a love, that you are not even sure if your loved one loves and cares about you too? Antu is a letter, and much more than a book, from a despaired lover to his love of life, for whom he has waited for an age! He has gone through the pain of numerous attempts of failed proposals, failed words, failed and broken hope and the excruciating pain of slowly letting go of her! He had become a poet in the disguise of a failed lover, and he had become a failed lover in the disguise of an idiosyncrasy of being cared and loved by her! If you too have gone through such things, you may get a connect to this! However, Antu remains an inspiration and an apparition!
Eco-toxicology, an offshoot of toxicology, is a multidisciplinary science that integrates toxicology and ecology by drawing knowledge and procedures from both fields. It analyses the effects of toxic chemicals or biological agents on living organisms at different levels of organization. Eco-toxicology classifies different contaminants, their characteristics, release and ecological fate, and predicts their effects so that timely action can be taken to prevent or minimize any detrimental effects. Environmental Toxicology starts with the basics of toxicology, briefly touching on the sources of toxic compounds, classification of toxicants, and factors affecting toxicity, and then elaborates on heavy metal toxicity. The individual chapters on various heavy metals and radioactive metals discuss the sources and routes of exposure, aetiology, pathophysiology, clinical manifestations, and mechanisms of toxicity, toxicological effects, diagnosis, treatment, management, and ecological impact. The book covers the field in its greatest width and provides an insight into pesticide and radiation toxicity, and recent advances in eco-toxicology, with special focus on the removal of HMs and the latest bioremediation techniques. This book serves as a reference work for advanced students pursuing degrees in environmental toxicology and across various disciplines, such as biomedical and environmental sciences, toxicology, eco-toxicology, pharmacology, public health, etc. and all interested in learning the concepts of eco-toxicology. Features: A systematic overview of the key concepts of eco-toxicology, its relationship with other disciplines, and recent advances in the area Detailed classification of toxicants, types of toxicity, and mechanism of the action of toxicants An in-depth coverage of topics on the mechanism toxicity of HMs, in addition to exclusive sections on pesticide and radiation toxicity A fact file in each chapter, highlighting its key points Flow charts, tables, diagrams, and illustrations in easily understandable language
As Indians, we are capable of creating plenty of positive energy, achieving economic growth and working towards upliftment of society with moral values. However, in recent times, we have lost the track and energy to do so, probably due to trust deficit about political leadership of our country. Modi Era highlights how energetic leadership can change people’s mindset and bring positivity with enthusiasm, efficiency, speed, scale and quality. If so many changes can be brought in just 4 years, imagine what can be achieved in the coming years if the same leadership continues. Read and decide for yourself…
Multilinguality gained a new impetus in North India with the influx of West Asian Muslim communities around the thirteenth century. Over a period of time, it entered everyday life as well as creative and scholarly pursuits. The fifteenth century, in particular, saw unprecedented vitality for literary practice, and the poet-scholar Vidyapati from Mithila was one of the many luminaries of the time. This volume encompasses an intimate linguistic, literary, and historical study of three of Vidyapati’s major works: a Sanskrit treatise on writing (Likhanāvalī); a celebratory biography in Apabhraṃśa (Kīrttilatā); and a collection of mythohistorical tales in Sanskrit (Puruṣaparīkṣā ). Through this examination, the author reveals a world that is marked by a range of ideas, expertise, literary tropes, ethical regimes, and historical consciousness, drawn eclectically from sources that belong to ‘diverse’ politico-cultural traditions. Using Vidyapati’s narratives, A Political History of Literature illustrates that many ideals extolled in fifteenth century literary cultures were associated with an imperial state—a state that was a century away from coming into being—and testifies that ideas incubate and get actualized in realpolitik only in the long duration.
This book discusses the perception of disease, healing concepts and the evolution of traditional systems of healing in the Himalayas of Himachal Pradesh, India. The chapters cover a diverse range issues: people and knowledge systems, healing in ancient scriptures, concept of sacredness and faith healing, food as medicament, presumptions about disease, ethno-botanical aspects of medicinal plants, collection and processing of herbs, traditional therapeutic procedures, indigenous Materia medica, etc. The book also discusses the diverse therapeutic procedures followed by Himalayan healers and their significance in the socio-cultural life of Himalayan societies. The World Health Organization defines traditional medicine as wisdom, skills, and practices based on theories, beliefs, and experiences indigenous to different cultures, used in the prevention, diagnosis, improvement or treatment of physical and mental illness and maintenance of health. In some Asian and African countries, 80% of the population depends on traditional medicine for primary health care. However, the knowledge of these conventional healing techniques and traditions associated with conveying this knowledge are slowly disappearing. The authors highlight the importance of safeguarding this indigenous knowledge in the cultural milieu of the Himachal Himalayas. This book will be an important resource for researchers in medical anthropology, biology, ethno-biology, ecology, community health, health behavior, psychotherapy, and Himalayan studies.
Development of high-throughput technologies in molecular biology during the last two decades has contributed to the production of tremendous amounts of data. Microarray and RNA sequencing are two such widely used high-throughput technologies for simultaneously monitoring the expression patterns of thousands of genes. Data produced from such experiments are voluminous (both in dimensionality and numbers of instances) and evolving in nature. Analysis of huge amounts of data toward the identification of interesting patterns that are relevant for a given biological question requires high-performance computational infrastructure as well as efficient machine learning algorithms. Cross-communication of ideas between biologists and computer scientists remains a big challenge. Gene Expression Data Analysis: A Statistical and Machine Learning Perspective has been written with a multidisciplinary audience in mind. The book discusses gene expression data analysis from molecular biology, machine learning, and statistical perspectives. Readers will be able to acquire both theoretical and practical knowledge of methods for identifying novel patterns of high biological significance. To measure the effectiveness of such algorithms, we discuss statistical and biological performance metrics that can be used in real life or in a simulated environment. This book discusses a large number of benchmark algorithms, tools, systems, and repositories that are commonly used in analyzing gene expression data and validating results. This book will benefit students, researchers, and practitioners in biology, medicine, and computer science by enabling them to acquire in-depth knowledge in statistical and machine-learning-based methods for analyzing gene expression data. Key Features: An introduction to the Central Dogma of molecular biology and information flow in biological systems A systematic overview of the methods for generating gene expression data Background knowledge on statistical modeling and machine learning techniques Detailed methodology of analyzing gene expression data with an example case study Clustering methods for finding co-expression patterns from microarray, bulkRNA, and scRNA data A large number of practical tools, systems, and repositories that are useful for computational biologists to create, analyze, and validate biologically relevant gene expression patterns Suitable for multidisciplinary researchers and practitioners in computer science and biological sciences
This monograph covers uniqueness of micromorphology in resolving many important but enigmatic pedological issues such as clay illuviation, formation of pedogenic and non-pedogenic CaCO3, modification of plasmic fabric, contemporary and relict pedogenic processes, polygenesis of soils in Alfisols, Mollisols, Ultisols, Vertisols and Inceptisols of the tropical Indian environments. Chapters in this title also include identification of paleosols, diagenetic overprinting of the pedofeatures in lithified paleosols, and alluvial cyclicity of the fluvial successions. The techniques mentioned in this title are of tremendous value in pedological and geological research for precise and unambiguous definitions of soil taxa to build the national soil information and refine the stratigraphy of the terrestrial sediments. The information is for the benefit the students and researchers of pedology and geomorphology who often come across extreme difficulties in relating to examples applying the principles of soil formation from textbooks devoted almost exclusively to soils of the temperate climates. The format of this publication is arranged for a process-oriented text and figures on micromorphology of the tropical soils and paleosols as a reference for pedologists, earth scientists, M.Sc. and Ph.D. students, and also for land resource managers who are engaged in enhancing the productivity of such tropical soils in India and elsewhere.
From last few decades’ composite materials, ceramics and plastics has made a mark in the field of materials. Applications of these materials in engineering arespecially attributed to their low specific weight and comparatively high strength. Applications of composite materials vary from the basic daily needs to sophisticated luxury applications. The demand of natural fiber in the composite materials has been increased owing to low density, low cost and biodegradable properties of natural fiber.But at the same time the natural fibers has certain disadvantages viz. they are hydrophilic in nature due to which there is poor incompatibility of natural fiber with the matrix. This intensity of this disadvantage can be reduced with the help of chemical treatment of natural fibers. Natural fiber has tendency of water absorption, which can also be reduced with chemical treatment. There are number of factors which affect the properties of natural fiber reinforced composite viz. fabrication method, environment condition during fabrication, fiber and its quantity, matrix material. Any slight modification in the above said variables leads to change in the properties of the final composite material. In the present work, the tensile and flexural properties of natural fiber (abaca fiber) reinforced TPU composites have been investigated. The content of natural fiber in composites has been varied from 0 to 30 wt%. The reinforced fibers were chemically treated with NaOH followed by treatment with maleic anhydride in acetone, prior to fabricating of samples by injection moulding. It is observed that the composite containing 10 wt% of abaca fiber has highest tensile strength among all the composites fabricated for this study, whereas the tensile strength of pure TPU sample has maximum among all the samples fabricated during this research work.Maximum flexural strength is observed ofthe composite containing 30 wt% of abaca fiber.SEM examinations of the fractured surface reveal that primary failure mechanisms in composite as fiber fracture and fiber pull-out.
This book examines the inclusive development experiences and impacts of the Mahatma Gandhi National Rural Employment Guarantee Scheme (MGNREGS). It discusses the theoretical assumptions underlying the inclusive development of Employment Guarantee Scheme (EGS), and draws conclusions based on robust data and real-world experiences with the MGNREGS – which has attracted global attention as India’s most ambitious, rights-based development initiative and most expansive work-based social security measure, the world’s largest public works programme, and people-centric approach to development. The book argues that the Scheme holds vast potential, and, in fact, has made significant contribution to the promotion of livelihoods of the poorest of the poor, but that the weak institutions of local-self-governance, entrusted for implementation of the Scheme, are incapable of exploiting them to the full. It ends with a concrete policy suggestion: the inclusive development experiences gathered with the EGS and presented here could offer a source of policy change in many developing Afro-Asian countries whose situations are similar to India’s, provided the local conditions in the respective country are taken into consideration when designing the EGS. Its significance as a social security measure has increased in post-COVID loss of jobs and livelihoods of the poor.
Indian Administration is a critical and analytical guide to all the important aspects of public administration in India. Based on books, journals, notes, files and government reports in the field, it examines the government and the administration at every level and tier. Its wide coverage includes all the major landmarks in the evolution of Indian administration, panchayati raj and urban local government after the constitutionalization of local government in India, as well as district planning and the District Planning Committee. It also addresses the issues plaguing our bureaucracy, making full use of reports from the Administrative Reforms Commission and various other committees. Comprehensive and well-researched, this book will fulfil the needs of students of political science and public administration, as well as candidates for civil service examinations, and will also be a valuable resource to scholars, administrators and the general reader interested in the subject.
A New York Times Notable Book of 2017 • Named a Best Book of the Year by Slate and NPR • Longlisted for the Orwell Prize One of our most important public intellectuals reveals the hidden history of our current global crisis How can we explain the origins of the great wave of paranoid hatreds that seem inescapable in our close-knit world—from American shooters and ISIS to Donald Trump, from a rise in vengeful nationalism across the world to racism and misogyny on social media? In Age of Anger, Pankaj Mishra answers our bewilderment by casting his gaze back to the eighteenth century before leading us to the present. He shows that as the world became modern, those who were unable to enjoy its promises—of freedom, stability, and prosperity—were increasingly susceptible to demagogues. The many who came late to this new world—or were left, or pushed, behind—reacted in horrifyingly similar ways: with intense hatred of invented enemies, attempts to re-create an imaginary golden age, and self-empowerment through spectacular violence. It was from among the ranks of the disaffected that the militants of the nineteenth century arose—angry young men who became cultural nationalists in Germany, messianic revolutionaries in Russia, bellicose chauvinists in Italy, and anarchist terrorists internationally. Today, just as then, the wide embrace of mass politics and technology and the pursuit of wealth and individualism have cast many more billions adrift in a demoralized world, uprooted from tradition but still far from modernity—with the same terrible results. Making startling connections and comparisons, Age of Anger is a book of immense urgency and profound argument. It is a history of our present predicament unlike any other.
Sustainable world economy requires a steady supply of crude oil without any production constraints. Thus, the ever-increasing energy demand of the entire world can be mostly met through the enhanced production from crude oil from existing reservoirs. With the fact that newer reservoirs with large quantities of crude oil could not be explored at a faster pace, it will be inevitable to produce the crude oil from matured reservoirs at an affordable cost. Among alternate technologies, the chemical enhanced oil recovery (EOR) technique has promising potential to recover residual oil from matured reservoirs being subjected to primary and secondary water flooding operations. Due to pertinent complex phenomena that often have a combinatorial role and influence, the implementation of chemical EOR schemes such as alkali/surfactant/polymer flooding and their combinations necessitates upon a fundamental understanding of the potential mechanisms and their influences upon one another and desired response variables. Addressing these issues, the book attempts to provide useful screening criteria, guidelines, and rules of thumb for the identification of process parametric sets (including reservoir characteristics) and response characteristics (such as IFT, adsorption etc.,) that favor alternate chemical EOR systems. Finally, the book highlights the relevance of nanofluid/nanoparticle for conventional and unconventional reservoirs and serves as a needful resource to understand the emerging oil recovery technology. Overall, the volume will be of greater relevance for practicing engineers and consultants that wish to accelerate on field applications of chemical and nano-fluid EOR systems. Further, to those budding engineers that wish to improvise upon their technical know-how, the book will serve as a much-needed repository.
The book aims to provide a review of the current status of knowledge on the subject of malaria especially from the perspective of affected countries. This fourth edition has been extensively updated to present in depth knowledge for not only the clinicians.But also teachers, General practitioners and undergraduate and postgraduate medical students.
A Handbook on Commercial Court Practice is a short commentary on the Commercial Courts Act, 2015. The Code of Civil Procedure was amended by the Commercial Courts Act, 2015 to mark the distinction between non-commercial and commercial suits. The first part of the book provides an overview of all such amended provisions which apply to commercial suits exclusively. The second part of the book contains brief commentaries on topical issues of the law of contract like the interpretation of contract, breach of contract, contract damages, penalty, privity of contract, etc. on which a practitioner argues in the Court. This quick reference book may come to the aid of all those who are to conduct commercial cases in the specially designated courts.
This manual is a comprehensive guide to Assisted Reproductive Technologies (ART) and Clinical Embryology. Beginning with an introduction to ART, the book discusses embryology and provides a step by step description of different types of ART. With contributions from international experts, this book includes a DVD illustrating different laboratory and cryobiology protocols. A section on the challenges of ART and possible problems that may be encountered is also included.
This publication presents the results of more than five consecutive years of focused research initiatives and designs from The University of Virginia School of Architecture towards the revitalization of New Delhi, India’s water bodies. In collaboration with the Delhi Jal Board, The University of Virginia’s Yamuna River Project is an inter-disciplinary research program, proposing to revitalize the ecology of the Yamuna River in Delhi and creating vital urban links with the Yamuna River as it flows through India’s capital city. Through the research, methodologies, and designs contained within this publication, this project aims to serve as a catalyst for the urgent recovery of the Yamuna River and its tributaries, building a publically accessible body of information and expertise resulting in visions of what an alternative future would be. Only by addressing human equality and the complexity of Delhi’s urban phenomenon can the social and ecological crises manifested through these neglected water bodies be solved.
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