Implantable cardioverter-defibrillators (ICDs) are electronic devices installed in the chest to prevent sudden death caused by abnormally fast heart rhythms. Cardiac electrophysiologists are the physicians usually responsible for implanting and maintaining these devices. The technology for ICDs is rapidly evolving, and the articles in this issue will help electrophysiologists to keep up to date with the current generation of ICDs, including selection of patients who are appropriate for the device, monitoring patients after the device is implanted, and troubleshooting problems with the device.
Written, reviewed, and edited in a collaborative effort by cardiology fellows and faculty of one of the most prestigious academic centers in the country, this concise volume gives cardiology fellows the book they have long needed. Keeping coverage of the underlying pathophysiology and mechanism of disease to a minimum, the authors focus on the diagnosis and treatment of cardiac disorders. Practical and easily accessible at the time of decision making, the book relays important concepts through concise and to-the-point pearls and by utilizing algorithm charts and illustrations.
Resynchronization and Defibrillation for Heart Failure: A Practical Approach is one of the first texts to provide caregivers with information about the background and application of this new and rapidly expanding discipline. Its four authors are cardiologists who have expertise in device management, electrophysiology, and heart failure management. The text integrates the approach and management experience of the authors’ three institutions. The aim is to bring together information from subspecialists in device management, electrophysiology, and heart failure management in an effort to facilitate the care of the patient with CRT.
From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
Pain Management in Vulnerable Populations addresses the clinical problem of pain in vulnerable populations in our society. Their vulnerability is related to the challenging nature of their clinical conditions, for which standard therapies are often ineffective, or social factors, structural to the nation's health system, that limit access to the personalized, multidisciplinary specialty and integrative care that is needed. Each vulnerable group demands a unique approach - this book reveals the details behind the history, examination, and therapeutic options.to remediate vulnerability and achieve quality care in these populations.
In the ever-evolving landscape of molecular diagnostics, we find ourselves at a unique intersection of science, technology, and human health. This book embarks on an in-depth exploration of the transformative power of molecular diagnostic technologies, which have revolutionized our understanding of microbial pathogens and their impact on global health. From the dawn of molecular biology to the sophisticated diagnostics of today, the journey has been nothing short of extraordinary. Advances in genomic technologies, such as next-generation sequencing and CRISPR-based diagnostics, have not only enhanced our ability to detect and characterize pathogens but have also paved the way for personalized medicine and precision healthcare. These innovations have provided clinicians with unprecedented tools to diagnose, treat, and manage a myriad of infectious diseases with greater accuracy and efficiency. This comprehensive volume is designed to serve as both a foundational text and forward-looking guide for researchers, clinicians, and policymakers involved in the field of molecular diagnostic microbiology. It into the intricate of pathogen detection, the clinical applications of these technologies, and the ethical, legal, and social implications that accompany their use. The chapters ahead will take you through the principles of nucleic acid extraction, the nuances of bioinformatics in diagnostics, and the critical aspects of quality assurance in laboratory settings. You will also discover the emerging trends and future directions in molecular diagnostics, offering a glimpse into the next frontier of microbial exploration. This book is a testament to the collaborative efforts of scientists, healthcare professionals, and regulatory bodies worldwide, who strive to harness the full potential of molecular diagnostics for the betterment of human health. It is our hope that the insights and knowledge contained within these pages will inspire continued innovation and foster a deeper understanding of the vital role that molecular diagnostics play in modern medicine. We invite you to join us on this journey through the fascinating world of molecular diagnostic microbiology, where each discovery brings us closer to a future where the mysteries of infectious diseases are unraveled, and the promise of personalized medicine is fully realized.
Reintroduction of Fish and Wildlife Populations provides a practical step-by-step guide to successfully planning, implementing, and evaluating the reestablishment of animal populations in former habitats or their introduction in new environments. In each chapter, experts in reintroduction biology outline a comprehensive synthesis of core concepts, issues, techniques, and perspectives. This manual and reference supports scientists and managers from fisheries and wildlife professions as they plan reintroductions, initiate releases of individuals, and manage restored populations over time. Covering a broad range of taxonomic groups, ecosystems, and global regions, this edited volume is an essential guide for academics, students, and professionals in natural resource management.
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. These phages played a unique role in early studies of molecular biology, the genetic code, translation, replication, suppression of mutations. Special attention is devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery, evolutionary and environmental studies. Included is an overview of the generation of novel vaccines, gene therapy vectors, drug delivery, and diagnostic tools exploring the role of RNA phage-derived products in the revolutionary progress of the protein tethering and bioimaging protocols. Key Features Presents the first full guide to single-stranded RNA phages Reviews the history of molecular biology summarizing the role RNA phages in the development of the life sciences Demonstrates how RNA phage-derived products have resulted in nanotechnological applications Presents an up-to-date account of the role played by RNA phages in evolutionary and environmental studies
The Jefferson Heart Institute Handbook of Cardiology offers a comprehensive, easily navigable guide to cardiac disorders and their treatment for residents, general internists and practicing cardiologists. This important compendium covers everything from arrhythmias to hemodynamics, fully preparing physicians to assess their cardiac patients at the point of care. Several chapters are devoted to reviewing methodologies and uses of the most up-to-date imaging technology such as echocardiography and CT/MR. As the U.S. population ages, physicians of all stripes will need to become increasingly familiar with cardiac disorders in general and heart failure in particular. The Jefferson Heart Institute Handbook of Cardiology stands out as the authoritative text designed to address this need, packaged in the most concise, readily accessible format available. Key Features: Expert treatment recommendations for a range of cardiac disorders Detailed guidance on cardiac imaging, including indications and methodologies Clinical chapters on patient prevention and disease management Trusted information from the renowned Jefferson Heart Institute
Electrochromic devices have a number of important commercial applications, for instance in displays, as optical shutters, and as modulators for mirrors, windows, and sun-glasses. Electrochromism - Fundamentals and Applications is the first in-depth treatise on the topic. Written by leading scientists in the field, it is a state-of-the-art account of all aspects of electrochromism, presented at a level accessible to chemists, physicists, materials scientists and engineers. Both the physical and chemical background of electrochromic phenomena are described and a comprehensive survey of both organic and inorganic compounds and systems is given. Special emphasis is placed on providing detailed, hands-on information on applications and potential uses of electrochromic systems. This book is essential reading for scientists active in the field and for anyone wishing to enter the field. An extensive list of carefully chosen references rounds off this valuable reference source.
In recent years, nanocomposites have captured and held the attention and imagination of scientists and engineers alike. Based on the simple premise that by using a wide range of building blocks with dimensions in the nanosize region, it is possible to design and create new materials with unprecedented flexibility and improvements in their physical properties. This book contains the essence of this emerging technology, the underlying science and motivation behind the design of these structures and the future, particularly from the perspective of applications. It is intended to be a reference handbook for future scientists and hence carries the basic science and the fundamental engineering principles that lead to the fabrication and property evaluation of nanocomposite materials in different areas of materials science and technology.
This new edition of The Standard Model and Beyond presents an advanced introduction to the physics and formalism of the standard model and other non-abelian gauge theories. It provides a solid background for understanding supersymmetry, string theory, extra dimensions, dynamical symmetry breaking, and cosmology. In addition to updating all of the experimental and phenomenological results from the first edition, it contains a new chapter on collider physics; expanded discussions of Higgs, neutrino, and dark matter physics; and many new problems. The book first reviews calculational techniques in field theory and the status of quantum electrodynamics. It then focuses on global and local symmetries and the construction of non-abelian gauge theories. The structure and tests of quantum chromodynamics, collider physics, the electroweak interactions and theory, and the physics of neutrino mass and mixing are thoroughly explored. The final chapter discusses the motivations for extending the standard model and examines supersymmetry, extended gauge groups, and grand unification. Thoroughly covering gauge field theories, symmetries, and topics beyond the standard model, this text equips readers with the tools to understand the structure and phenomenological consequences of the standard model, to construct extensions, and to perform calculations at tree level. It establishes the necessary background for readers to carry out more advanced research in particle physics. Supplementary materials are provided on the author’s website and a solutions manual is available for qualifying instructors.
From the development of each vaccine to its use in reducing disease, Plotkin's Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues – plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Covers the new oral cholera and zoster vaccines, as well as newly licensed meningococcal group B vaccines and a newly licensed dengue vaccine. - Brings you up to date on successful human trials of Ebola vaccines, an enterovirus 71 vaccine licensed in China, and new recommendations and changes to polio vaccines. - Features a new chapter on maternal immunization. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Widely recognized as the gold standard reference in the field, Rosen’s Breast Pathology provides comprehensive, up-to-date information on diseases of the breast from renowned experts at four leading medical centers, masterfully edited by Dr. Paul P. Rosen. The revised fifth edition covers the latest advances in immunohistochemical, pathobiological, and molecular aspects of benign and malignant breast diseases, helping you reach an accurate diagnosis with confidence. It’s an ideal reference for all physicians and medical personnel who require a thorough knowledge of breast pathology, including pathologists, surgeons, oncologists, radiologists, and radiation oncologists.
Ideal for cardiologists, surgeons, and referring physicians who need a clinical guide to interventional procedures, Textbook of Interventional Cardiology focuses on the latest treatment protocols for managing heart disorders at every level of complexity. In this updated edition, Dr. Topol continues to bring together experts in the field who present the current state of knowledge and clinical practice in interventional cardiology, including cutting-edge theories, trends, and applications of diagnostic and interventional cardiology, as well as peripheral vascular techniques and practices. Offers an in-depth understanding of cardiology, making it well suited for cardiology and interventional cardiology exam preparation. Expert guidance from leading authorities ensures a fresh and balanced perspective on every aspect of interventional cardiology. Presents the most recent genetic information and clinical trials related to interventional cardiology. Highlights the latest treatment advances, procedures, devices, and techniques, including transcatheter aortic valve implantation (TAVI). Brand-new chapters include Radiation Safety, Renal Denervation for Resistant Hypertension, Post PCI Hospitalization, Length of Stay and Discharge Planning, and Interventional Heart Failure. Offers balanced coverage of the entire scope of technologies available, without favoring one particular device over another. Integrates the latest trial data into discussions on clinical practice and recommendations. Multiple images of devices and intra-procedural imaging enhance your visual understanding of the material. Key Points boxes at the beginning of each chapter summarize the most important facts.
The Plant Paradox meets The Keto Reset Diet. In this best-selling book, Dr. Paul Saladino-a rising star in the Paleo and Keto communities-reveals the surprising benefits of a meat-based diet and shares a complete plan to lose weight, decrease inflammation, and heal from chronic disease.
Atomic force microscopy (AFM) is an amazing technique that allies a versatile methodology (that allows measurement of samples in liquid, vacuum or air) to imaging with unprecedented resolution. But it goes one step further than conventional microscopic techniques; it allows us to make measurements of magnetic, electrical or mechanical properties of the widest possible range of samples, with nanometre resolution. This book will demystify AFM for the reader, making it easy to understand, and to use. It is written by authors who together have more than 30 years experience in the design, construction, and use of AFMs and will explain why the microscopes are made the way they are, how they should be used, what data they can produce, and what can be done with the data. Illustrative examples from the physical sciences, materials science, life sciences, nanotechnology and industry demonstrate the different capabilities of the technique.
What Went Wrong? 6th Edition provides a complete analysis of the design, operational, and management causes of process plant accidents and disasters. Co-author Paul Amyotte has built on Trevor Kletz's legacy by incorporating questions and personal exercises at the end of each major book section. Case histories illustrate what went wrong and why it went wrong, and then guide readers in how to avoid similar tragedies and learn without having to experience the loss incurred by others. Updated throughout and expanded, this sixth edition is the ultimate resource of experienced-based analysis and guidance for safety and loss prevention professionals. - 20% new material and updating of existing content with parts A and B now combined - Exposition of topical concepts including Natech events, process security, warning signs, and domino effects - New case histories and lessons learned drawn from other industries and applications such as laboratories, pilot plants, bioprocess plants, and electronics manufacturing facilities
Offering expert, comprehensive guidance on the basic science, diagnosis, and treatment of acute musculoskeletal injuries and post-traumatic reconstructive problems, Skeletal Trauma, 6th Edition, brings you fully up to date with current approaches in this challenging specialty. This revised edition is designed to meet the needs of orthopaedic surgeons, residents, fellows, and traumatologists, as well as emergency physicians who treat patients with musculoskeletal trauma. International thought leaders incorporate the latest peer-reviewed literature, technological advances, and practical advice with the goal of optimizing patient outcomes for the full range of traumatic musculoskeletal injuries. - Offers complete coverage of relevant anatomy and biomechanics, mechanisms of injury, diagnostic approaches, treatment options, and associated complications. - Includes eight new chapters dedicated to advances in technology and addressing key problems and procedures, such as Initial Evaluation of the Spine in Trauma Patients, Management of Perioperative Pain Associated with Trauma and Surgery, Chronic Pain Management (fully addressing the opioid epidemic), Understanding and Treating Chronic Osteomyelitis, and more. - Features a complimentary one-year subscription to OrthoEvidence, a global online platform that provides high-quality, peer-reviewed and timely orthopaedic evidence-based summaries of the latest and most relevant literature. Contains unique, critical information on mass casualty incidents and war injuries, with contributions from active duty military surgeons and physicians in collaboration with civilian authors to address injuries caused by road traffic, armed conflict, civil wars, and insurgencies throughout the world. - Features important call out boxes summarizing key points, pearls and pitfalls, and outcomes. - Provides access to nearly 130 instructional videos that demonstrate principles of care and outline detailed surgical procedures. - Contains a wealth of high-quality illustrations, full-color photographs, and diagnostic images. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Lead innovation and raise the standard of care in your OR with new techniques and proven practical approaches. Filled with current, clinically relevant presentations and approaches, Instructional Course Lectures, Volume 70 offers solutions for the most current issues and challenges faced at all stages of your career. Broaden your treatment options with experience-based solutions from some of today’s most respected surgeons and specialty experts.
This practical, hands-on guide helps beginning researchers create a mixed methods research proposal for their dissertations, grants, or general research studies. The book intertwines descriptions of the components of a research proposal (introduction, literature review, research methods, etc.) with discussions of the essential elements and steps of mixed methods research. Examples from a real-world, interdisciplinary, mixed methods research study demonstrate concepts in action throughout the book, and an entire sample proposal appears at the end of the book, giving readers insight into every step up to completion. Readers who complete the exercises in each chapter will have an individualized, detailed template for their own mixed methods research proposal. Developing a Mixed Methods Proposal is Volume 5 in the SAGE Mixed Methods Research Series.
From the latest vaccination evidence, recommendations, and protocols . . . to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. - Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. - Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. - Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. - Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful. It also discusses the basic biology of miRNA sythesis, regulation, and their role in disease biology.
Ideal for cardiologists, surgeons, and referring physicians who need a clinical guide to interventional procedures, Textbook of Interventional Cardiology focuses on the latest treatment protocols for managing heart disorders at every level of complexity. In this updated edition, Dr. Topol continues to bring together experts in the field who present the current state of knowledge and clinical practice in interventional cardiology, including cutting-edge theories, trends, and applications of diagnostic and interventional cardiology, as well as peripheral vascular techniques and practices. Offers an in-depth understanding of cardiology, making it well suited for cardiology and interventional cardiology exam preparation. Expert guidance from leading authorities ensures a fresh and balanced perspective on every aspect of interventional cardiology. Presents the most recent genetic information and clinical trials related to interventional cardiology. Highlights the latest treatment advances, procedures, devices, and techniques, including transcatheter aortic valve implantation (TAVI). Brand-new chapters include Radiation Safety, Renal Denervation for Resistant Hypertension, Post PCI Hospitalization, Length of Stay and Discharge Planning, and Interventional Heart Failure. Offers balanced coverage of the entire scope of technologies available, without favoring one particular device over another. Integrates the latest trial data into discussions on clinical practice and recommendations. Multiple images of devices and intra-procedural imaging enhance your visual understanding of the material. Key Points boxes at the beginning of each chapter summarize the most important facts. Features 45 videos easily accessible via Expert Consult. Expert Consult eBook version included with purchase. This enhanced eBook experience offers access to all of the text, figures, videos, and references from the book on a variety of devices.
This book is the first of its kind to introduce and evaluate the molecular techniques that have been developed to authenticate Chinese medicinal materials.
Drawing on practices and theories of sustainability, Environmental policy and sustainable development in China explores the prospects for achieving environmentally benign economic and social development in China and beyond. Using the Chinese 'world city' of Hong Kong as a backdrop and case study, it introduces major conceptions of sustainability, describes historical and political contexts for environmental policymaking, and analyses key challenges related to sustainable development, including air pollution, water quality, waste, transport and climate change. The book will be a valuable and unique resource for students, teachers and readers interested in environmental policy, sustainable development and ecological governance, especially in China and Hong Kong. All of the author's royalties from sales of this book will be donated by Policy Press to Friends of the Earth (Hong Kong) and WWF (Hong Kong).
Where experts turn for definitive answers! Clinical Anesthesia covers the full spectrum of clinical issues and options in anesthesiology, providing insightful coverage of pharmacology, physiology, co-existing diseases, and surgical procedures. Unmatched in its clarity and depth of coverage as well as its robust multimedia features, this classic clinical reference brings you the very latest essential knowledge in the field, equipping you to effectively apply today’s standards of care and make optimal clinical decisions on behalf of your patients.
Enhance your surgical skills with Atlas of Oral and Maxillofacial Surgery, 2nd Edition! Written by respected international contributors and edited by OMS experts Paul Tiwana and Deepak Kademani, the new edition of this practical, comprehensive guide is divided into two volumes with eBook access included with the print purchase. It offers detailed, step-by-step instructions and more than 2,500 full-color illustrations that demonstrate how to plan for and perform oral and maxillofacial surgical procedures safely and efficiently. Comprehensive and expanded coverage addresses the broad scope of the specialty, ranging from the surgical anatomy of the head and neck to oral surgery, implant surgery, orthognathic and craniofacial surgery, cleft lip and palate, craniomaxillofacial trauma, head and neck oncology, reconstructive procedures, TMJ surgery, facial cosmetic surgery, obstructive sleep apnea, and more. - Comprehensive, consistent approach to OMS operative procedures offers practical guidance for the management of patients with oral and maxillofacial disorders, with each surgical procedure chapter approximately six to eight pages in length and covering the following topics: armamentarium, history of the procedure, indications for use of the procedure, limitations and contraindications, technique, alternate or modified technique, avoidance and management of intraoperative complications, and postoperative considerations. - More than 2,500 images include vibrant, modern medical illustrations and clinical photos that make up the heart of each surgical chapter and bring it to life visually. - Detailed, step-by-step approach shows how to perform OMS surgical procedures safely and efficiently. - Coverage of alternative and modified techniques addresses options beyond the standard techniques. - Expert, international contributors provide authoritative guidance on the OMS procedures they typically perform. - NEW! Two-volume extended edition is easier to navigate and includes extensive updates throughout. - NEW! More than 30 new chapters expand the coverage of implants, craniofacial surgery, and facial cosmetic surgery — plus an all-new section discusses obstructive sleep apnea (OSA). - NEW! An eBook version included only with print purchase allows you to access all the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Consisting of 13 chapters, this book is uniformly written to provide sensible, matter-of-fact methods for understanding and caring for patients with permanent pacemakers, ICDs and CRT systems. Now improved and updated, including a new chapter on programming and optimization of CRT devices, this second edition presents a large amount of information in an easily digestible form. Cardiac Pacing and Defibrillation offers sensible, matter-of-fact methods for understanding and caring for patients, making everyday clinical encounters easier and more productive. Readers will appreciate the knowledge and experience shared by the authors of this book.
Self-adaptive software evaluates its own behavior and changes its behavior when the evaluation indicates that the software does not accomplish what it is intended to do or when better functionality or better performance is possible. The self-adaptive approach in software engineering builds on well-known features like the use of errors and the handling of exceptions in languages like Lisp or Java and aims at improving the robustness of software systems by gradually adding new features of self-adaption and autonomity. This book originates from the First International Workshop on Self-Adaptive Software, IWSAS 2000, held in Oxford, UK in April 2000. The revised full papers presented in the volume together with an introductory survey by the volume editors assess the state of the art in this emerging new field and set the scene for future research and development work.
This second edition of The Illustrated Wavelet Transform Handbook: Introductory Theory and Applications in Science, Engineering, Medicine and Finance has been fully updated and revised to reflect recent developments in the theory and practical applications of wavelet transform methods. The book is designed specifically for the applied reader in science, engineering, medicine and finance. Newcomers to the subject will find an accessible and clear account of the theory of continuous and discrete wavelet transforms, while readers already acquainted with wavelets can use the book to broaden their perspective. One of the many strengths of the book is its use of several hundred illustrations, some in colour, to convey key concepts and their varied practical uses. Chapters exploring these practical applications highlight both the similarities and differences in wavelet transform methods across different disciplines and also provide a comprehensive list of over 1000 references that will serve as a valuable resource for further study. Paul Addison is a Technical Fellow with Medtronic, a global medical technology company. Previously, he was co-founder and CEO of start-up company, CardioDigital Ltd (and later co-founded its US subsidiary, CardioDigital Inc) - a company concerned with the development of novel wavelet-based methods for biosignal analysis. He has a master’s degree in engineering and a PhD in fluid mechanics, both from the University of Glasgow, Scotland (founded 1451). His former academic life as a tenured professor of fluids engineering included the output of a large number of technical papers, covering many aspects of engineering and bioengineering, and two textbooks: Fractals and Chaos: An Illustrated Course and the first edition of The Illustrated Wavelet Transform Handbook. At the time of publication, the author has over 100 issued US patents concerning a wide range of medical device technologies, many of these concerning the wavelet transform analysis of biosignals. He is both a Chartered Engineer and Chartered Physicist.
Now in its 6th edition, Cummings Otolaryngology remains the world's most detailed and trusted source for superb guidance on all facets of head and neck surgery. Completely updated with the latest minimally invasive procedures, new clinical photographs, and line drawings, this latest edition equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. Be certain with expert, dependable, accurate answers for every stage of your career from the most comprehensive, multi-disciplinary text in the field! Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. Experience clinical scenarios with vivid clarity through a heavily illustrated, full-color format which includes approximately 3,200 images and over 40 high quality procedural videos. Get truly diverse perspectives and worldwide best practices from a multi-disciplinary team of contributors and editors comprised of the world’s leading experts. Glean all essential, up-to-date, need-to-know information. All chapters have been meticulously updated; several extensively revised with new images, references, and content. Stay at the forefront of your field with the most updated information on minimally-invasive surgical approaches to the entire skull base, vestibular implants and vestibular management involving intratympanic and physical therapy-based approaches, radiosurgical treatment of posterior fossa and skull base neoplasms, and intraoperative monitoring of cranial nerve and CNS function. Apply the latest treatment options in pediatric care with new chapters on pediatric sleep disorders, pediatric infectious disease, and evaluation and management of the infant airway. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference. Manage many of the most common disorders with treatment options derived from their genetic basis. Assess real-world effectiveness and costs associated with emergent technologies and surgical approaches introduced to OHNS over the past 10 years. Incorporate recent findings about endoscopic, microscopic, laser, surgically-implantable, radiosurgical, neurophysiological monitoring, MR- and CT-imaging, and other timely topics that now define contemporary operative OHNS. Take it with you anywhere! With Expert Consult, you'll have access the full text, video clips, and more online, and as an eBook - at no additional cost!
This book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter’s arrangement. The term "VLP" is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions. Key Features Presents the first full guide to the VLP nanotechnology, classified by current viral taxonomy Outlines specific structural properties and interconnection of the virions and VLPs Explains generation and characteristics of VLPs produced by various expression systems Offers up-to-date summary of VLPs designed as vaccines and delivery tools Unveils interconnection of VLPs with novel organic and inorganic nanomaterials
Regularization becomes an integral part of the reconstruction process in accelerated parallel magnetic resonance imaging (pMRI) due to the need for utilizing the most discriminative information in the form of parsimonious models to generate high quality images with reduced noise and artifacts. Apart from providing a detailed overview and implementation details of various pMRI reconstruction methods, Regularized image reconstruction in parallel MRI with MATLAB examples interprets regularized image reconstruction in pMRI as a means to effectively control the balance between two specific types of error signals to either improve the accuracy in estimation of missing samples, or speed up the estimation process. The first type corresponds to the modeling error between acquired and their estimated values. The second type arises due to the perturbation of k-space values in autocalibration methods or sparse approximation in the compressed sensing based reconstruction model. Features: Provides details for optimizing regularization parameters in each type of reconstruction. Presents comparison of regularization approaches for each type of pMRI reconstruction. Includes discussion of case studies using clinically acquired data. MATLAB codes are provided for each reconstruction type. Contains method-wise description of adapting regularization to optimize speed and accuracy. This book serves as a reference material for researchers and students involved in development of pMRI reconstruction methods. Industry practitioners concerned with how to apply regularization in pMRI reconstruction will find this book most useful.
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