The rapid and continuous upsurge of interesting data in the subject of tumor immunology necessitates the publication of an annual series to furnish the updated materials to the students, researchers, and clinicians in this rapidly advancing field. Concepts and methodologies are ever changing. Also, current research in tumor immunology promises to offer breakthroughs in the future. Important is the need to communicate to the right people the exact role of immunodiagnostic methods and immunolog ical intervention in cancer prevention and treatment. The role of immuno therapy in combination with conventional modalities of treatment needs in its proper perspective. Oncogene, interferon, lympho to be understood kines, monoclonal antibodies, natural killer cells, platelet-mediated cyto toxicity of antibody-coated target cells, suppressor cells, platelet-derived factors, plasma-blocking factors, control of suppressor cell function, ab rogation of plasma-blocking factors, etc. , are some of the areas that are continually advancing. Progress in these areas will have implication in cancer therapy. Further, it is already understood that if immunocompe tence of the host can be maintained at a reasonably good level, there exists the potential to increase the therapeutic indexes of conventional modalities of treatment. This series will attempt to present updated infor mation in all these areas based on contributed and solicited articles. P. K.
This book is aimed at those in the biomedical community that are interested in the therapeutic applications, pharmacology, biochemistry, toxicology and pharmacokinetics of the title compounds. Recent findings regarding the ability of diethyldithiocarbamate (ditiocarb, Imuthiol®) to delay the progression of HN infections and AIDS, the discovery of its potential as a rescue agent in cancer chemotherapy, and the identification of disulfiram (Antabuse®) regimens that allow alcoholics to achieve abstinence of many months' duration have made writing this book an exciting experience. At the same time the fact that the two drugs differ substantially in their pharmacological effects in spite of their easy interconvertibility has rendered the writing intellec tually challenging. Diethyldithiocarbamate, an agent seemingly less toxic than aspirin, rivals it in the multiplicity and diversity of its pharmacological proper ties. Notable among these are the manyfold potent immunostimulant effects, and though most of these involve effects on T -cells, the mechanism of diethyldithiocarbamate's action remains far from clear. The drug is also a potent chelator of heavy metals and this has led to a number of clinical applications. As might be expected, it inhibits several important enzymes. Further, it is one of the most effective radioprotective agents; it also protects organisms against a variety of toxic agents.
Maintaining the interdisciplinary perspective of the first edition, this reference and text provides comprehensive discussions of all aspects of fiber-reinforced composites, including materials, mechanics, properties, test methods, manufacturing and design. Written from a conceptual point of view and emphasizing fundamentals, the second edition of Fiber Reinforced Composites offers updated and expanded sections including: fibers and matrix, including thermoplastic matrices; discontinuous fibers and laminated structures; static mechanical properties, fatigue properties and damage tolerance; resin flow, bag molding, filament winding and resin transfer molding; and environmental effects.
The advent of the era of "e-Service," the provision of services over electronic networks like the internet, is one of the dominant business themes of the new millennium. It reflects the fundamental shift in the economy from goods to services and the explosive expansion of information technology. This book provides a collection of different perspectives on e-Service and a unified framework to understand it, even as the business community grapples with the concept. It features contributions from key researchers and practitioners from both the private and public sectors, as well leading scholars from the fields of marketing, information systems, and computer science. They focus on three key areas: the customer-technology interface; e-Service business opportunities and strategies; and public sector e-Service opportunities. The insights they offer will be equally useful to students, scholars, and practitioners.
At the end of the last century and the beginning of this century, the prob lems of immunity in lower vertebrates and the influence of environmental temperature attracted attention for the first time (ERNST, 1890; WIDAL and SICARD, 1897; METCHNIKOFF, 1901). However, relatively little work has been done on this subject until recently. The early investigators were chiefly in terested in the immuno-pathological problems. They immunized various species of lower vertebrates essentially with bacterial vaccines; agglutinating, neutralizing and protective antibodies were detected in their blood. The in fluence of environmental temperature on the immune response was investigated, since this subject represented great economical and theoretical importance. Epizootic diseases were observed to occur in relation to the cold season of the year, when the decrease or spontaneous increase of water temperature occurred (SCHAPERCLAUS, 1965; BESSE et al. , 1965; KLONTZ et al. , 1965 WOOD,1966). The immunological deficiency of fish, caused by their natural or experimental stay in cold water, is now evident for both humoral and cellular immunity. In this review we will focus on two points: We shall attempt (1) to explain the mechanism by which the environmental temperature influences the immune resistance of fish to pathogens, (2) to determine the chronological location of this temperature-sensitive stage in the process of antibody formation, and to make some approaches to the general antibody formation mechanism.
The immobilized biocatalyst (IMB) is a key component of biotransformation systems that are used to transform substrates to desired products. The impro- ment of biocatalyst properties has a direct influence on the overall effectiveness of the process based on the biotransformation. The basic catalytic characte- stics of biocatalyst that are followed include kinetic properties, pH optima, stability, and inhibition. The investigation of catalytic properties of immobilized enzymes is still a time consuming procedure and is not always simple. In the 1980s, a major effort was made to standardize the rules by which IMB is char- terized. The Working Party of EFB on immobilized biocatalysts has formul- ed principles of individual methods, among them the requirement of kinetic characterization [1]. It was recommended to use a packed-bed reactor, equipped with temperature control and with infinite flow circulation. The system should be equipped with a post-column unit to measure the time-dependence of the product or substrate concentration [2, 3], the most commonly used analytical methods being spectrophotometry, chemiluminiscence, automatic titration, bioluminiscence, chromatography, polarimetry, and biosensors based on the oxygen electrode. There are two main drawbacks to the application of these methods: 1. The need to vary the analytical principles, depending on the chemical and physical-chemical properties of analytes; 2. In some cases, mainly in the study of hydrolytic enzymes, the natural s- strate must be replaced by an artificial one, that is chromolytic, chromogenic, chemiluminiscent, bioluminiscent, or fluorescent.
Phenomena as diverse as tuberculin sensitivity, delayed sensitivity to soluble proteins other than tuberculin, contact allergy, homograft rejection, experimental autoallergies, and the response to many microorganisms, have been classified as members of the class of immune reactions known as delayed or cellular hypersensitivity. Similarities in time course, histology, and absence of detectable circulating immunoglobulins characterize these cell-mediated immune reactions in vivo. The state of delayed or cellular hypersensitivity can be transferred from one animal to another by means of sensitized living lymphoid cells (CHASE, 1945; LANDSTEINER and CHASE, 1942; MITCHISON, 1954). The responsible cell has been described by GOWANS (1965) as a small lymphocyte. Passive transfer has also been achieved in the human with extracts of sensitized cells (LAWRENCE, 1959). The in vivo characteristic of delayed hypersensitivity from which the class derives its name is the delayed skin reaction. When an antigen is injected intradermally into a previously immunized animal, the typical delayed reaction begins to appear after 4 hours, reaches a peak at 24 hours, and fades after 48 hours. It is grossly characterized by induration, erythyma, and occasionally necrosis. The histology of the delayed reaction has been studied by numerous investigators (COHEN et al., 1967; GELL and HINDE, 1951; KOSUNEN, 1966; KOSUNEN et al., 1963; MCCLUSKEY et al., 1963; WAKSMAN, 1960; WAKSMAN, 1962). Initially dilatation of the capillaries with exudation of fluid and cells occurs.
‘How could I have imagined so surrealist and seductive a world? One does not like the heat, yet its constancy, its all-surroundingness, is as fascinating as the smell of musk. Every moment is slow, as if under warm greenish water....’ In 1957, Page moved to Brazil with her husband, the Canadian ambassador. The hot, lush landscape was utterly immersive -- and for the next three years Page recorded her life in an intimate, vibrant, startlingly funny journal. Between her at times theatric responsibilities as the wife of an ambassador, and her futile attempts to organize the ambassador’s palatial home and staff, Page found the time to write in exquisite prose of her responses to the wildlife, the people and the colours of Brazil, in the end illuminating more of her own emotional and artistic journey than of the country itself. Accompanied by several of the illustrations Page created while on her travels, this is a fascinating, beautiful account of life in a magically unfamiliar place. Brazilian Journal is the second addition to a series of volumes to be published over the next ten years as a complement to an online hypermedia edition of the Collected Works of P.K. Page. The online edition is intended for scholarly research, while this new edition offers a beautiful text to be enjoyed by those who love and wonder at the talent of one of Canada’s greatest poets.
I Was Lucky By: Paul “PK” Kimminau I Was Lucky: I Got to Be a Pilot is the story of a young boy from Kansas who watched World War II fighters fly over his town. With two older brothers who went through the Aviation Cadet program and became Air Force pilots, it was natural that he also wanted to become a pilot. The Air Force ROTC program at the University of Wichita was the path he chose to get his commission as an Air Force officer and, subsequently, earn his pilot wings. Over a 21-year career, “PK” traveled the world flying fighter planes for the United States Air Force. This is the story of his adventures, good, bad, fun, and not-so-fun.
Expression of an immune response is the net result of complex synergis tic and antagonistic activities performed by a variety of cell types. It includes macrophages, T and B populations which may interact in performance of a response, and suppressor cells interfering with it. Accordingly, a lack of res ponse may not necessarily indicate absence of immunocompetent cells, but rather nonexpression of competence. Thus, one should consider two possible situations, which are by no means mutually exclusive, to account for immuno logic unresponsiveness: (a) one or more of the cell populations composing the synergistic unit is absent or immature, and (b) an antagonistic unit which interferes with the response is dominating. In view of this, an approach to development of immune reactivity necessitates parallel surveys of development of cells with the potential to perform, as well as of cells which can suppress the response. Classification of the various cell types has been based so far on their phenotypic properties (e. g. , membrane antigen markers, cell receptors, pro duction and secretion of immunoglobulins, etc. ). Genotypically, T and B cells may represent either separate, independent cell lines, or different stages of development within the same cell lineage.
This edition is presented in a totally new and reader-friendly format. The focus of this volume is on holistic management of critically ill adult patients and it builds upon concepts one step at a time – allowing one the opportunity to develop competence at one's own pace.
PART I Molecular Biology 1. Molecular Biology and Genetic Engineering Definition, History and Scope 2. Chemistry of the Cell: 1. Micromolecules (Sugars, Fatty Acids, Amino Acids, Nucleotides and Lipids) Sugars (Carbohydrates) 3. Chemistry of the Cell . 2. Macromolecules (Nucleic Acids; Proteins and Polysaccharides) Covalent and Weak Non-covalent Bonds 4. Chemistry of the Gene: Synthesis, Modification and Repair of DNA DNA Replication: General Features 5. Organisation of Genetic Material 1. Packaging of DNA as Nucleosomes in Eukaryotes Techniques Leading to Nucleosome Discovery 6. Organization of Genetic Material 2. Repetitive and Unique DNA Sequences 7. Organization of Genetic Material: 3. Split Genes, Overlapping Genes, Pseudogenes and Cryptic Genes Split Genes or .Interrupted Genes 8. Multigene Families in Eukaryotes 9. Organization of Mitochondrial and Chloroplast Genomes 10. The Genetic Code 11. Protein Synthesis Apparatus Ribosome, Transfer RNA and Aminoacyl-tRNA Synthetases Ribosome 12. Expression of Gene . Protein Synthesis 1. Transcription in Prokaryotes and Eukaryotes 13. Expression of Gene: Protein Synthesis: 2. RNA Processing (RNA Splicing, RNA Editing and Ribozymes) Polyadenylation of mRNA in Prokaryotes Addition of Cap (m7G) and Tail (Poly A) for mRNA in Eukaryotes 14. Expression of Gene: Protein Synthesis: 3. Synthesis and Transport of Proteins (Prokaryotes and Eukaryotes) Formation of Aminoacyl tRNA 15. Regulation of Gene Expression: 1. Operon Circuits in Bacteria and Other Prokaryotes 16. Regulation of Gene Expression . 2. Circuits for Lytic Cycle and Lysogeny in Bacteriophages 17. Regulation of Gene Expression 3. A Variety of Mechanisms in Eukaryotes (Including Cell Receptors and Cell Signalling) PART II Genetic Engineering 18. Recombinant DNA and Gene Cloning 1. Cloning and Expression Vectors 19. Recombinant DNA and Gene Cloning 2. Chimeric DNA, Molecular Probes and Gene Libraries 20. Polymerase Chain Reaction (PCR) and Gene Amplification 21. Isolation, Sequencing and Synthesis of Genes 22. Proteins: Separation, Purification and Identification 23. Immunotechnology 1. B-Cells, Antibodies, Interferons and Vaccines 24. Immunotechnology 2. T-Cell Receptors and MHC Restriction 25. Immunotechnology 3. Hybridoma and Monoclonal Antibodies (mAbs) Hybridoma Technology and the Production of Monoclonal Antibodies 26. Transfection Methods and Transgenic Animals 27. Animal and Human Genomics: Molecular Maps and Genome Sequences Molecular Markers 28. Biotechnology in Medicine: l.Vaccines, Diagnostics and Forensics Animal and Human Health Care 29. Biotechnology in Medicine 2. Gene Therapy Human Diseases Targeted for Gene Therapy Vectors and Other Delivery Systems for Gene Therapy 30. Biotechnology in Medicine: 3. Pharmacogenetics / Pharmacogenomics and Personalized Medicine Phannacogenetics and Personalized 31. Plant Cell and Tissue Culture' Production and Uses of Haploids 32. Gene Transfer Methods in Plants 33. Transgenic Plants . Genetically Modified (GM) Crops and Floricultural Plants 34. Plant Genomics: 35. Genetically Engineered Microbes (GEMs) and Microbial Genomics References
Plant breeding has undergone a period of very rapid and significant development in recent years and the area of fruit breeding is no exception. This book provides a balanced, up-to-date and comprehensive account of the developments in the field of breeding tropical and subtropical fruits. It offers not only the theoretical and applied aspects of breedings fruits but also provides an authoritative manual of the conventional and new techniques used for increasing efficiency of crop improvement programmes. In specific chapters the book deals with crop taxonomy, genetic resources, floral biology, breeding objectives, inheritance patterns and information on new improved cultivars/hybrids.
Reliability Engineering and Quality Management provides a competitive advantage and market leadership in a global environment where market barriers are fast disappearing both in the domain of cutting edge and contemporary technologies, manufacturing, process and service sectors like information technology sector. The growth of Q & R has been fuelled by increasing sophistication and complexity of system and organisational awareness to produce and market high quality and reliability products and services by the consumer and global market pressures. This subject being interdisciplinary in nature has also brought about a convergence of numerous solution strategies employing Fuzzy Sets, Artificial Neural Nets, Modeling and Simulation, Knowledge Base Systems, Operations Research and Mathematical Programming to achieve high Reliability. This book is intended for both the beginner and practitioner from manufacturing and service sector, research laboratories and academic institutions. This book is unique also as it gives an insight into the current practices and future directions.
The book is designed to cover the recent researches carried-out by the scholars from across the world. It covers aspects related to Foraminifera, in biostratigraphy and paleoecology, isotopic studies, applicability as bio-indicators in pollution studies, taxonomy of Indo-Pacific assemblages, studies of history of ocean bottom oxygenation and experimental studies; Radiolaria from Antarctic Ocean; Microbalites including Diatoms in studying threats and conservation issues in salt lakes of Western Australia; Ostracoda from freshwater, marginal marine ecosystems from Andaman and Nicobar islands; Coralline-algae from late Eocene rocks of Meghalaya; Zygnematalean algae from across the Permian-Triassic boundary; and Microstructures of egg-shells of vertebrates showing paleobiologic links across the continents. It will serve the postgraduate students choosing Geology as well as researchers in the field of Micropaleontology.
The absence of a book dealing with rubber processing has been apparent for some time and it is surprising that a straightforward text has not been produced. However, this book goes far beyond the scope of a simple technical approach and deals with the full spectrum of activities which lead to successful and profitable product manufacture. The need to deliver a product to a customer at the right time, at the right cost, and at the right quality is a basic premise on which the book is based. The increasingly stringent demands of customers for products that can be introduced directly into an assembly or production line without goods inwards inspection, are placing increasing pressures on the manufacturer. As a result, it is becoming essential to achieve and sustain product quality and consistency, by the monitoring and control of manufacture, at a level which renders all products saleable. The book has been written to satisfy the needs of practitioners in the rubber industry and is certainly not another descriptive text which is only read for interest when more important matters are not pressing. My close cooperation with Philip K. Freakley during the writing of the book has resulted in the incorporation of many of the viewpoints and methods which I have developed and refined during more than 38 years in the rubber industry.
Contents: V. Zingel, C. Leschke and W. Schunack: Developments in research on histamine (H1) receptor agonists / P.D. Hoeprich: Antifungal chemotherapy / G. de Stevens: The diversity of heterocyclic compounds and their biological activities / R.M. Schultz: Newer antifolate compounds in cancer therapy / P.K. Mehrotra, S. Batra and A.P. Bhadun: Non-steroidal agents for regulation of the menstrual cycle / A.K. Saxena and M. Saxena: Developments in anti-convulsant drugs
The economic paradigms currently dominating the world are not sustainable. The threats from climate change, exploitation-based approaches to commerce, and the excess acquisition of resources loom large as well as the possibility of military flare-ups. Maintaining a balance between development and ecosystems, aspirations for growth, and the need for sustainability is a prescient challenge. The Indian Ocean Region (IOR) encompasses some of the poorest countries in the world and those that will bear the brunt of the negative impacts from climate change. This book explores the immense potential of the IOR and how best to maintain sustainable and responsible economic and strategic activities. The combination of science, innovation, and entrepreneurship will create a new blue economy business model, which has the potential to transform society. Based on critical analysis of the model and its practical applications, including risks as well as opportunities, the topics discussed range from food security, energy, and resilience to climate change, trade and investments, and improved maritime connectivity to tourism, poverty alleviation, and socioeconomic growth, encompassing a wide range of interests and expertise. FEATURES Examines the geo-politics, geo-resources, and geo-hazards of the IOR and identifies opportunities and methods to achieve success Covers a detailed assessment of available resources (fisheries, minerals, energy), threats such as pollution (plastic, acoustic, carbon, bio-invasion), geo-politics (maritime security, military invasion), and strategic vision (determining carrying capacity, ethical governance, and responsible ecosystem) of the Indian Ocean Analyzes the economics of the blue economy, the global scenario including the Pacific and Caribbean islands, and the aspect of the Chinese geo-political invasion in the Indian Ocean Inspires entrepreneurs to adopt new ways of creating economic benefits, reducing energy use, and increasing revenue while simultaneously helping the communities involved Discusses the threat and security perspectives of the IOR and the collective responsibility for a sustainable use of resources Crossing a wide range of interests and expertise, this book explores topics and ideas that will be essential to researchers and professionals in marine sciences, economics, business, geography, and political sciences. Graduate students in the same fields as well as any and all organizations that maintain a presence in the IOR will likewise find this book to be a valuable resource.
Biological diversity encompasses all species of animals, plants, micro-organisms, ecosystem and ecological processes of which they are part. Biodiversity provides the basis for life on earth. The more we know about Earth's biological diversity, the better will be our capability to conserve both terrestrial and aquatic ecosystems. Expanding human population, overexploitation of natural resources, habitat loss and pollution are contributing to a great extent to the rapid degradation of environmental quality, with its irreversible loss or depletion of species diversity. The current perception is therefore to frame strategies to conserve biodiversity otherwise the future generation will blame us for robbing them for their life support systems. This book includes original research articles on various aspects of Biodiversity and its Conservation presented by eminent Scientists working within the country and abroad. Most of the concepts are new and pertinent to Indian context. This book will be of immense utility to the Researchers and Post-Graduate students engaged in varied areas of Biodiversity conservation.
This Book, Structured Around The Strategic Management Process Model, Focuses On Conceptual Understanding Of Process And Articulation Of Strategies. Uptodate And Well Researched, It Includes Many Case Studies, Numerous Exhibits And Boxed Highlights And Review Questions.
Revised and updated version of the last edition keeping its clear and systematic style intact with complimentary access to e-book with digital resources like MCQs, videos, animations• A new chapter on Nystagmus• Revised & updated topics enriched with additional photographs, figures and diagrams• Many disorders that were listed just by name in the last edition have been given small description for ready reference.• Complimentary access to e-book with digital resources: o University and PGMEE patterned MCQs o Procedure videos and animations • In-depth discussion of signs, symptoms and history taking• Practical tips and points useful in day-to-day clinical practice• Highlights applied anatomical and physiological principles underlining each procedure• Systematic presentation of information – each chapter devoted to specific system of eye
Understanding and predicting the structure and properties of woven textiles is important for achieving specific performance characteristics in various woven applications. Woven textiles are used in a range of products such as apparel, technical and industrial textiles. Woven textile structure: Theory and applications provides comprehensive coverage of the structure, behaviour, modeling and design of woven fabrics and their relevance to the textile industry.The first group of chapters review the fundamental principles of woven fabric structures. Part two discusses the mechanics of woven fabrics, topics include shrinkage in woven fabrics, yarn behaviour in woven fabrics and bending behaviour of woven fabrics. Part three presents a selection of chapters on design engineering of woven fabrics, themes such as textile product design methods and modelling for woven fabric design are covered. A final group of chapters is dedicated to addressing practical applications of woven fabrics.Woven textile structure: Theory and applications is essential reading for designers, engineers and technicians involved in the design, manufacture and use of woven textiles and garments. It will also bebeneficial to academics and students. - Provides comprehensive coverage of the fundamentals of woven fabric structure including geometrical modeling - Examines mechanisms of woven fabric structure featuring shrinkage, buckling, bending and creasing behaviour of textiles - Illustrates mathematical modeling and building predictive models for textile product design incorporating validation and testing
P.K. Page is best known as one of Canada's finest poets, but over the course of her career she has also written a number of essays – meditations – on her life and work, on the nature of art and the imagination, and on Canadian works of literature, painting, and film that have had special significance for her. As lovers of her poetry would hope and expect, these essays are beautiful, intelligent, moving, and delightfully quirky. The Filled Pen brings together the most important of these essays, including two previously unpublished: A Writer's Life and Fairy Tales, Folk Tales: The Language of the Imagination.. Zailig Pollock, Page scholar and professor of English at Trent University, has edited and annotated this collection for admirers of Page's work, general readers, and academics alike. The essays, which cover a period of approximately forty years, reflect Page's enduring concerns as a verbal and visual artist with the power of art and the imagination to transcend the barriers that limit our perceptions of the world and our sympathies with our fellow human beings. Page is more interested in posing questions than imposing answers; and fascinated as she is by a wide range of ideas, from ancient mysticism to modern neurophysiology, it is images, endlessly evocative and suggestive, that matter to her most. Her comments on A.M. Klein from "A Sense of Angels", one of the most moving and perceptive tributes by one poet to another, apply very much to the P.K. Page we see in The Filled Pen: "For all his interest in the immediate world ... for all his acceptance of ideological and psychological theory, he seemed to reach beyond both to a larger reality.
Agroforestry – the practice of growing trees and crops in interacting combinations – is recognized the world over as an integrated approach to sustainable land-use. Agroforestry systems, being multifunctional, facilitate not only the production of food and wood products but also provide a variety of ecosystem services such as climate-change mitigation, biodiversity conservation, and soil quality improvement. Agroforestry research has made rapid strides since organized efforts started in the late 1970s. Today, a vast body of scientific knowledge and an impressive array of publications on agroforestry are available. Four World Congresses on Agroforestry conducted once every five years since 2004 have brought together the global community of agroforestry professionals and practitioners to share and discuss the emerging trends and paradigm shifts in this field. The fifth Congress is scheduled to be held in Québec, Canada. However, a comprehensive college-level textbook incorporating these research findings did not exist until this book was first published. The first edition of this book in 1993 (Nair, P. K. R., 1993) is out of print and somewhat dated. This revised edition, with emphasis on the scientific developments during the past more than four decades, addresses this long-felt need.
This book maps out the frontiers of optical technology in two major subdisciplines: optical materials and optical devices. The optical materials and material architectures covered include nanostructured silicon, chiral sculptured thin films, magnetic photonic crystals, and switchable materials for efficient lighting and decorative optics. The optical devices addressed include silicon waveguides for integrated circuitry, high-speed electro-optic modulators, laser diodes coupled with fibre-tip lenses, and optical sensors. Reading the ten chapters, either altogether or piecemeal, the reader will receive a virtually up-to-date review of the state of the art.
Known for her award-winning poetry and her intricate visual art, P. K. Page did not consider herself a writer of fiction, but she nevertheless produced a substantial and varied body of compelling stories. Triptych: Selected Fiction of P. K. Page presents powerful examples of Page’s insightful and provocative fiction. Characterized by the exploration of charged ideas, these works (including a novel, several short stories, and a collection of brief linked narratives) take inspiration from experience both lived and imagined. In them, Page meditates on the notion of memory and the process of remembering, delving into themes of imagination and identity, of art and the environment, all the while maintaining the language and lyricism epitomized in her poetry. With a critical introduction by volume editor Elizabeth Popham, Triptych not only reproduces the captivating and lyrical prose of one of Canada’s most beloved authors, but also provides readers with a tantalizing glimpse into the extension of the poet-artist’s oeuvre and her development as a skillful writer of fiction.
What if you discovered the Artifacts from the fairy tales were real and one of them just predicted your death? That's the dilemma Scientist Ben Michaels faces when Siene Dower, descendant of the Brothers Grimm, tells him that Snow White's Magic Mirror sent her to stop him from getting into the cab that crashed and burst into flame right before his eyes at the intersection at Penn Station, New York City. Does practical Dr. Michaels dismiss everything he knows about reality and science and follow the curious and beautiful woman who just saved his life?
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