How well can you answer pet owners' questions about proper diet and feeding? Canine and Feline Nutrition, 3rd Edition describes the role of nutrition and its effects upon health and wellness and the dietary management of various disorders of dogs and cats. By using the book's cutting-edge research and clinical nutrition information, you'll be able to make recommendations of appropriate pet food and proper feeding guidelines. Pet nutrition experts Linda P. Case, MS, Leighann Daristotle, DVM, PhD, Michael G. Hayek, PhD, and Melody Foess Raasch, DVM, provide complete, head-to-tail coverage and a broad scope of knowledge, so you can help dog and cat owners make sound nutrition and feeding choices to promote their pets' health to prolong their lives. - Tables and boxes provide quick reference to the most important clinical information. - Key points summarize essential information at a glance. - A useful Nutritional Myths and Feeding Practices chapter dispels and corrects common food myths. - New clinical information covers a wide range of emerging nutrition topics including the role of the omega-3 and omega-6 fatty acid families in pet health and disease management. - Coverage of pet food safety and pet food ingredients includes both commercially and home-prepared foods and provides answers to pet owners' questions on these topics. - Completely updated content reflects the latest findings in clinical nutrition research. - Information regarding functional ingredients and dietary supplementation provides a scientifically based rationale for recommending or advising against dietary supplements. - Guidelines for understanding pet food formulations and health claims differentiate between "market-speak" and actual clinical benefits for patients, with practice advice for evaluating and selecting appropriate foods.
Principles of Research Design and Drug Literature Evaluation is a unique resource that provides a balanced approach covering critical elements of clinical research, biostatistical principles, and scientific literature evaluation techniques for evidence-based medicine. This accessible text provides comprehensive course content that meets and exceeds the curriculum standards set by the Accreditation Council for Pharmacy Education (ACPE). Written by expert authors specializing in pharmacy practice and research, this valuable text will provide pharmacy students and practitioners with a thorough understanding of the principles and practices of drug literature evaluation with a strong grounding in research and biostatistical principles. Principles of Research Design and Drug Literature Evaluation is an ideal foundation for professional pharmacy students and a key resource for pharmacy residents, research fellows, practitioners, and clinical researchers. FEATURES * Chapter Pedagogy: Learning Objectives, Review Questions, References, and Online Resources * Instructor Resources: PowerPoint Presentations, Test Bank, and an Answer Key * Student Resources: a Navigate Companion Website, including Crossword Puzzles, Interactive Flash Cards, Interactive Glossary, Matching Questions, and Web Links From the Foreword: "This book was designed to provide and encourage practitioner’s development and use of critical drug information evaluation skills through a deeper understanding of the foundational principles of study design and statistical methods. Because guidance on how a study’s limited findings should not be used is rare, practitioners must understand and evaluate for themselves the veracity and implications of the inherently limited primary literature findings they use as sources of drug information to make evidence-based decisions together with their patients. The editors organized the book into three supporting sections to meet their pedagogical goals and address practitioners’ needs in translating research into practice. Thanks to the editors, authors, and content of this book, you can now be more prepared than ever before for translating research into practice." L. Douglas Ried, PhD, FAPhA Editor-in-Chief Emeritus, Journal of the American Pharmacists Association Professor and Associate Dean for Academic Affairs, College of Pharmacy, University of Texas at Tyler, Tyler, Texas
The prevalence of urinary tract diseases and disorders in small animal practice is higher than ever. The 2nd edition of Canine and Feline Nephrology and Urology makes it easy to find the information you need to accurately diagnose and manage diseases and disorders of the urinary tract in dogs and cats. Its concise outline format features practical clinical content, line drawings that clearly illustrate the initiation and progression of disease, photographs that demonstrate the clinical appearance of various lesions, and tables and boxes that offer essential information at a glance. Expert authors Dennis J. Chew, Stephen P. DiBartola, and Patricia Schenck keep you current with revised and brand-new content based upon the latest studies and evidence-based medicine, helping you prevent and most effectively manage kidney, bladder, and related conditions. - Outline format with concise, clinically focused content helps you quickly and easily find the information you need to accurately diagnose and effectively manage urinary tract diseases and disorders. - Practical clinical tips and guidelines including algorithms, FAQs, and case management recommendations. - Special boxes highlight key information at a glance. - Concise, need-to-know information about renal and lower urinary tract pathophysiology provides essential background for clinical application. - Evidence-based coverage of hot topics such as the relationship between behavioral stressors and urinary tract disease, treatments for idiopathic cystitis, and dietary modifications for the prevention and treatment of urinary tract problems helps you provide the latest and best care for your patients.
The leading reference for the diagnosis and management of fluid, electrolyte, and acid-base imbalances in small animals, Fluid, Electrolyte, and Acid-Base Disorders in Small Animal Practice, 4th Edition provides cutting-edge, evidence-based guidelines to enhance your care of dogs and cats. Information is easy to find and easy to use, with comprehensive coverage including fluid and electrolyte physiology and pathophysiology and their clinical applications, as well as the newest advances in fluid therapy and a discussion of a new class of drugs called vaptans. Lead author Stephen DiBartola is a well-known speaker and the "go-to" expert in this field, and his team of contributors represents the most authoritative and respected clinicians and academicians in veterinary medicine. - Over 30 expert contributors represent the "cream of the crop" in small animal medicine, ensuring that this edition provides the most authoritative and evidence-based guidelines. - Scientific, evidence-based insights and advances integrate basic physiological principles into practice, covering patient evaluation, differential diagnosis, normal and abnormal clinical features and laboratory test results, approaches to therapy, technical aspects of therapy, patient monitoring, assessing risk, and prediction of outcomes for each disorder. - Hundreds of tables, algorithms, and schematic drawings demonstrate the best approaches to diagnosis and treatment, highlighting the most important points in an easy-access format. - Drug and dosage recommendations are included with treatment approaches in the Electrolyte Disorders section. - Clear formulas in the Fluid Therapy section make it easier to determine the state of dehydration, fluid choice, and administration rate and volume in both healthy and diseased patients. - Updated chapters cover the latest advances in fluid therapy in patient management, helping you understand and manage a wide range of potentially life-threatening metabolic disturbances. - Expanded Disorders of Sodium and Water chapter includes information on a new class of drugs called vaptans, vasopressin receptor antagonists that may soon improve the ability to manage patients with chronic hyponatremia. - Hundreds of new references cover the most up-to-date advances in fluid therapy, including renal failure and shock syndromes.
Alcohol use is complex and multifaceted. Our understanding must be also. Alcohol use, both problematic and not, can be understood at many levels – from basic biological systems through to global public health interventions. To provide the multi-level perspective needed to address this complexity, the Handbook of Alcohol Use draws together an eclectic set of authors, including both researchers and practitioners, to examine the causes, processes and effects of alcohol consumption. Specifically, this book approaches the topic from biological, individual cognition, small group/systems, and domestic/global population perspectives. Each examines alcohol use differently and each offers its own ways to combat problematic behavior. While these alternative viewpoints are sometimes construed as incompatible or antagonistic, the current volume also explores how they can be complimentary.In summary, the Handbook of Alcohol Use brings together an international group of experts to explore how alcohol use can be understood from various perspectives and how these conceptualizations relate. In doing so, it allows us to understand alcohol consumption, and our responses to it, more from an account which spans 'from synapse to society'. - Explores alcohol use from individual through to societal levels - Synthesizes these varied levels of analysis on alcohol use - Draws on an international team of experts including researchers and alcohol treatment practitioners - Makes clear the implications of research for practice (and vice versa)
Florida has been the location and subject of hundreds of feature films, from Cocoanuts (1929) to Monster (2004). Portraying the state and its people from the silent era to the present, these films have explored the multitude of Florida images and cliches that have captured the public's imagination--a nature lover's paradise, a wildlife refuge, a tourist destination, home to the "cracker," and a haven for the retired, the rich, the immigrant, and the criminal. Sunshine in the Dark is the first complete study of how the movie industry has immortalized Florida’s extraordinary scenery, characters, and history on celluloid. Historians Fernández and Ingalls have identified more than 300 films about Florida--many of them shot on location in the state--to analyze how filmmakers from the Marx Brothers and John Huston to Oliver Stone and Francis Ford Coppola have portrayed the state and its people. Prior to the 1960s, cinematic trips to Florida usually brought happy endings in movies like Moon Over Miami (1942), but since the 1970s, films like Scarface (1982) have emphasized the state's menacing aspects. In the authors' analysis of the films, which examines location settings, plotlines, and characters, they find a bevy of Florida stereotypes among the leading characters--from the struggling crackers in The Yearling (1946) to the drug-addicted con man in Adaptation (2002). Featuring more than 100 still photographs from movies, as well as filmographies by year and genre, the book is an encyclopedic resource for movie fans and anyone interested in Florida popular culture.
This book provides comprehensive knowledge of the methods of detection and identification of phyllosphere microbial pathogens and the management of different kinds of diseases caused by them in various crops. Interactions between pathogens and host plants result in the induction of defense responses expressed via molecular signals, from initiation of infection to systemic progression of pathogen invasion in susceptible plants and contrasting signals in resistant plants, leading to inhibition of pathogen development through activation of preinfectional and postinfectional defense responses. These are critically discussed. The author describes the intricate and complex competitive activities of the pathogens and host plants in a molecular warfare that the host plant must win to break the link in the pathogens' life cycle, allowing the development of disease management strategies based on the principles of exclusion, eradication, and immunization. Integration of strategies concerning the development of cultivars resistant to pathogens through breeding and biotechnological techniques, application of biotic and abiotic inducers of resistance to pathogens, and use of disease-free seeds and propagules that are complementary to each other along with effective cultural practices are emphasized. This book presents information gathered through an extensive literature search to help researchers and graduate students in agricultural sciences identify research gaps and successfully complete their research projects.
Adaptation to altitude hypoxia is characterized by a variety offunctional changes which collectively facilitate oxygen trans port from the ambient medium to the cells of the body. All of these changes can be seen at one time or another in the course of hypoxic exposure. Yet, as already stressed (Hannon and Vogel, 1977), an examination of the literature gives only a sketchy and often conflicting picture of the exact nature of these changes and how they interact as a function of exposure duration. This is partly because of the limited number of variables explored in a given study, but it is also attributable to differences in experimental design, differences among species in susceptibility to hypoxia, nonstandardized experimental conditions, lack of proper control of physical (e. g. , temperature) and physiological variables (e. g. , body mass), failure to take measurements at key periods of exposure, and gaps in knowledge about some fundamental mechanisms. Furthermore the available data on animals native to high altitude are meager and/or inconclusive. Extensive further work under well-controlled experimental conditions is required before a detailed picture can be made. Nevertheless, it has been a guiding principle in the prepara tion of this monograph rather to summarize the vastly dis persed material that constitutes the comparative physiology of adaptation to high altitude into a coherent picture, than to provide a comprehensive survey of the field.
Third edition of the go-to reference to college admission Getting into college has never been more complicated or competitive. Parents and students need expert guidance to navigate the maze of college admissions. This thoroughly updated edition of Admission Matters is the best source, covering the whole process for any applicant. The authors offer great practical advice for selecting the right school, writing effective essays, navigating financial aid, and much more. No matter what type of school a college-bound student may select, Admission Matters will give them the edge they need. Offers an essential resource for understanding the admission process for all students applying to college Addresses the most recent changes to the college application process New sections include information for international students, transfer students, and students with learning disabilities, as well as expanded advice for athletes, artists, and homeschoolers This is an essential handbook for any family facing the college admission process.
This thesis addresses two of the central processes which underpin the formation of galaxies: the formation of stars and the injection of energy into the interstellar medium from supernovae, called feedback. In her work Claudia Lagos has completely overhauled the treatment of these processes in simulations of galaxy formation. Her thesis makes two major breakthroughs, and represents the first major steps forward in these areas in more than a decade. Her work has enabled, for the first time, predictions to be made which can be compared against new observations which probe the neutral gas content of galaxies, opening up a completely novel way to constrain the models. The treatment of feedback from supernovae, and how this removes material from the interstellar medium, is also likely to have a lasting impact on the field. Claudia Lagos Ph.D. thesis was nominated by the Institute for Computational Cosmology at Durham University as an outstanding Ph.D. thesis 2012.
Different phases of fruit development and utilization have been treated in many textbooks, reviews, and a host of scientific and professional papers. This seems, however, to be the first attempt to bring together case histories of so many different fruits and to present a balanced account of the whole period from set to harvest. Postharvest physiology, which has been in the centre of the picture in many former books, is at the bored line of the subject matter of this book, and has not been fully covered, except in a few cases. For this reason, two separate chapters deal with physiological and pathological aspects of fruit life after harvest.
Current Techniques in Small Animal Surgery, Fifth Edition provides current information regarding surgical techniques from the perspective of clinicians who are performing specific procedures on a regular basis. It is intended to be concise, well illustrated, and reflective of the writer's experience, both good and bad. The emphasis with this volume
This unique, full-color reference offers a total team approach to radiation oncology treatment planning, incorporating the newest imaging techniques and offering a comprehensive discussion of clinical, physical, biological and technical aspects. A clear focus on the application of physical and clinical concepts to solve treatment planning problems helps you provide effective, state-of-the-art care for cancer patients. With authoritative coverage of the latest in sophisticated radiation oncology treatment modalities, the 4th Edition of Khan’s Treatment Planning in Radiation Oncology is an essential resource for the radiation oncologist, medical physicist, dosimetrist, and radiation therapist.
The approach of this concise but comprehensive introduction, covering all major classes of materials, is right for not just materials science students and professionals, but also for those in engineering, physics and chemistry, or other related disciplines. The characteristics of all main classes of materials, metals, polymers and ceramics, are explained with reference to real-world examples. So each class of material is described, then its properties are explained, with illustrative examples from the leading edge of application. This edition contains new material on nanomaterials and nanostructures, and includes a study of degradation and corrosion, and a presentation of the main organic composite materials. Illustrative examples include carbon fibres, the silicon crystal, metallic glasses, and diamond films. Applications explored include ultra-light aircraft, contact lenses, dental materials, single crystal blades for gas turbines, use of lasers in the automotive industry, cables for cable cars, permanent magnets and molecular electronic devices. - Covers latest materials including nanomaterials and nanostructures - Real-world case studies bring the theory to life and illustrate the latest in good design - All major classes of materials are covered in this concise yet comprehensive volume
Between 1915 and 1930, nine towns in the Blue Ridge Mountains of Pennsylvania, Maryland, and West Virginia hosted teams in one of the most successful Class D minor leagues in professional baseball. The Blue Ridge League launched the careers of legendary Hall of Famers Lefty Grove and Hack Wilson and served as a training ground or final stop for over 100 major-league players. This feisty league challenged laws prohibiting Sabbath baseball games (resulting in mass arrests of players and management), pioneered night baseball, served as a laboratory for the establishment of baseball's farm system, and helped develop a postseason five-state championship series.
This is the first major study of the convict in the Atlantic world of the eighteenth century. It concentrates on the diverse characters of the transported men, women and children, and their fate in the colonies, exploring at the local level the contrasts in sentencing, shipping and settlement of convicts in America. The central myths about transportation prevalent in the eighteenth century, particularly that most felons returned, are examined in the context of the burgeoning print culture of criminal biographies and newspaper stories. In addition, the exchange of representations between the two sides of the Atlantic, and the changing American reaction to convicts, are placed within the growing transatlantic debate on transportation before the American Revolution. Above all, the realities of escape, of convicts running away and returning to England, are subject to systematic investigation for the first time.
Chronic overconsumption of sugar and fat elevates plasma levels of insulin and free fatty acids, a process referred to as glucolipotoxicity. This phenomenon may lead to heart failure. This issue explores in depth the relationship between glucolipotoxicity and heart failure.
Large Animal Internal Medicine, 4th Edition features a problem-based approach with discussions of over 150 clinical signs. This is the first internal medicine reference that enables you to efficiently diagnose horses, cattle, sheep, and goats based on clinical observation and laboratory and diagnostic testing. With this user-friendly format, you can find essential information about specific diseases and reach a diagnosis by simply identifying the signs. A unique problem-based approach with discussions of over 150 clinical signs and manifestations helps you quickly reach a diagnosis based on observations and laboratory tests. Causes of Presenting Signs boxes provide easy access to complete lists of common, less common, and uncommon diseases associated with manifestations or signs of disease. Complete lists of diseases associated with a given lab abnormality in Causes of Abnormal Laboratory Values boxes help you easily interpret abnormalities in clinical chemistry, hematology, blood proteins, and clotting tests. An expert team of over 180 authors contributing information in their areas of expertise ensures you are using the most accurate and up-to-date information available. Color plates accompanying Diseases of the Eye and Diseases of the Alimentary Tract enable you to visually recognize the clinical appearance of ophthalmologic conditions and alimentary tract disorders for quick and easy diagnosis and treatment. Six all-new chapters provide in-depth coverage of diagnostic testing, critical care and fluid therapy, biosecurity and infection control, and genetic disorders.
Bioprocess technology involves the combination of living matter (whole organism or enzymes ) with nutrients under laboratory conditions to make a desired product within the pharmaceutical, food, cosmetics, biotechnology, fine chemicals and bulk chemicals sectors. Industry is under increasing pressure to develop new processes that are both environmentally friendly and cost-effective, and this can be achieved by taking a fresh look at process development; - namely by combining modern process modeling techniques with sustainability assessment methods. Development of Sustainable Bioprocesses: Modeling and Assessment describes methodologies and supporting case studies for the evolution and implementation of sustainable bioprocesses. Practical and industry-focused, the book begins with an introduction to the bioprocess industries and development procedures. Bioprocesses and bioproducts are then introduced, together with a description of the unit operations involved. Modeling procedures, a key feature of the book, are covered in chapter 3 prior to an overview of the key sustainability assessment methods in use (environmental, economic and societal). The second part of the book is devoted to case studies, which cover the development of bioprocesses in the pharmaceutical, food, fine chemicals, cosmetics and bulk chemicals industries. Some selected case studies include: citric acid, biopolymers, antibiotics, biopharmaceuticals. Supplementary material provides hands-on materials so that the techniques can be put into practice. These materials include a demo version of SuperPro Designer software (used in process engineering) and models of all featured case studies, excel sheets of assessment methods, Monte Carlo simulations and exercises. Previously available on CD-ROM, the supplementary material can now be accessed via http://booksupport.wiley.com by entering the author name, book title or isbn and clicking on the desired entry. This will then give a listing of all the content available for download. Please read any text files before downloading material.
Assessing both the macro- and micro-economic levels of the contemporary African Debt Crisis, this book, first published in 1989, begins by looking at the origins of the world debt crisis, and then looks closely at the problem as it affects Sub-Saharan Africa. The effects of debt on Africa’s position in international relations are considered, and the roles played by organisations such as the International Monetary Fund and the World Bank are assessed. The authors also examine the local effects in a series of case studies of various states including Nigeria, Ghana and Sierra Leone, the Francophone States and Zaire.
Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.
Drs. Helio Autran de Morais and Stephen DiBartola have assembled a comprehensive list of topics on Advances in Fluid, Electrolyte, and Acid-base Disorders. Just some of the many article topics include: Hypoxemia; Respiratory Alkalosis; Respiratory Acidosis; Anion gap and strong ion gap; Metabolic Alkalosis; Hyperchloremic Metabolic Acidosis; High Anion Gap Metabolic Acidosis; Hypercalcemia; Hypocalcemia; Chloride; Magnesium; Phosphorus; Practical management of dysnatremias; Spurious electrolyte disorders; Compensation for acid-base disorders; Fluid therapy: Options and rational selection; Maintenance fluid therapy: Isotonic versus hypotonic solutions; Are colloids bad and what are the options?; Fluid management in patients with trauma; Restrictive versus liberal approach, and more!
Placing Alexander the Great’s leadership, command skills, and grand strategy within the context of twenty-first century military challenges, and thus showing continuities in leadership and warfare since his time, this volume demonstrates how and why Alexander is relevant to the modern world by emphasizing the need for human leadership in our digital era. Not only does this volume explore Alexander’s rich military history, but also it provides a robust exploration of the twenty-first century security environment. Theorists and policy-makers will gain insight into how Alexander’s story informs our thinking about peace, war, and strategy, while practitioners and educators will encounter ways to improve their approaches to leader development and building curricula. Ferguson and Worthington set forth these lessons in a thematic framework that organises Alexander’s reign into distinct parts, together with chapters discussing the lessons and warnings he brings to the modern world. Twenty-fifth National Security Advisor to the President of the United States, Lt. Gen. H. R. McMaster, provides a thoughtful conclusion to this fascinating volume. Alexander’s timeless campaigns remain as germane to this age as any other and demonstrate the critical importance of dynamic leadership and historical studies in an era increasingly dominated by the culture of technology. The Military Legacy of Alexander the Great is expertly written for students and scholars in a variety of disciplines, including Classics, Ancient History, Modern History, Peace Studies, and Military Studies. It is also of great interest to senior defence leaders, military academies, leadership- and management-focused academic programmes, intelligence organizations, and senior service colleges. The volume is also suitable for the general reader interested in warfare, military history, and history more broadly.
The Handbook of Crime Correlates, Second Edition summarizes more than a century of worldwide research on traits and social conditions associated with criminality and antisocial behavior. Findings are provided in tabular form, enabling readers to determine at a glance the nature of each association. Within each table, results are listed by country, type of crime (or other forms of antisocial behavior), and whether each variable is positively, negatively, or insignificantly associated with offending behavior. Criminal behavior is broken down according to major categories, including violent crime, property crime, drug offenses, sex offenses, delinquency, and recidivism. This book provides a resource for practitioners and academics who are interested in criminal and antisocial behavior. It is relevant to the fields of criminology/criminal justice, sociology, and psychology. No other publication provides as much information about how a wide range of variables—e.g., gender, religion, personality traits, weapons access, alcohol and drug use, social status, geography, and seasonality—correlate with offending behavior. - Includes 600+ tables regarding variables related to criminal behavior - Consolidates 100+ years of academic research on criminal behavior - Findings are identified by country and world regions for easy comparison - Lists criminal-related behaviors according to major categories - Identifies universal crime correlates
Schizophrenic psychology is the study of mental processes and behaviour of schizophrenics. This book presents the latest research in this dynamic field.
Psychiatric genetics is an exciting new discipline that explores how our minds and behavior are influenced by our genes. Increased interest in this area of medical genetics has been sparked by advances in molecular genetic techniques, the genome project, the neurosciences, the role of genes in somatic diseases, and the linking of specific genes with complex mental disorders. This Handbook is the definitive resource on this complex, and sometimes controversial, new field.
Get the core knowledge in pain medicine you need from one of the most trusted resources in the field. The new fourth edition guides you through every aspect of pain medicine with concise descriptions of evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. From commonly seen pain syndromes, including headaches, trunk pain, orofacial pain, back pain, and extremity pain...through specific pain management challenges such as postoperative pain, pain due to cancer, phantom pain, and pain in the management of AIDS patients...this popular text will equip you with the know-how you need to effectively manage even your most challenging cases. A practical, multidisciplinary approach to pain management makes key concepts and techniques easier to apply to everyday practice. Expert contributors provide the latest knowledge on all aspects of pain management, from general principles through to specific management techniques. Detailed discussions of the latest concepts and treatment plans help you provide the best possible outcomes for all your patients. Extensively updated chapters acquaint you with the most current trends and techniques in pain management. A new section on complications helps you avoid and manage potential pitfalls. A new editorial team ensures that you are getting the freshest, most clinically relevant information available today. New, full-color art clarifies key concepts and techniques.
Many new ideas in project planning and cost control have been tried in the past 20 years. Some of them led to techniques taken for granted today. Others, that initially appeared logical and feasible, proved to be unworkable. Project Management supplies techniques that help with the planning and management of cost control. This book describes techniques currently used by systems engineers and project managers on major projects. It covers variations and modifications to suit different projects and management styles. The author takes a semi-procedural approach, using a minimum of words to give maximum information. He provides practical examples to illustrate each application. Experienced industrial managers know the essentials - good forward planning, budget control, and performance measurement - that maintain the viability of any project. Project Management puts these elements and functions into perspective. It gives experienced managers and young engineers alike the tools they need to see the big picture. Features
Alcohol abuse, alcohol intolerance, alcohol dependence and other alcohol-related disabilities are some of the most challenging public health problems facing our modern-day society. The purpose of this comprehensive monograph is to review the available knowledge concerning the pharmacogenetic basis of alcohol sensitivity and its physiolgical implications and to synthesize the bulk of existing knowledge regarding metabolic features and biomedical disturbances related to alcoholism. The chapters cover a broad array of disciplines including an overview of historical and epidemiological aspects, biochemistry and molecular genetics of enzymes involved in alcohol metabolism, biochemical and neuropsychopharmacological effects of alcohol. Major emphasis is placed on the role of genetic factors in alcoholism. The experimental details are summarized and a comprehensive bibliography is included.
Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease. - Over 145 full-color illustrations of the molecular and cellular cascades underlying the disease pathology. - Disease pathways are based on computational models from Elsevier's Disease Pathway Collection, published for the first time outside of Pathway Studio® commercial software. - Each relationship on the pathway models is supported by references to scientific articles and can be examined at freely available online resources.
This book is a survey of knowledge about binocular vision, with an emphasis on its role in the perception of a three-dimensional world. The primary interest is biological vision. In each chapter, physiological, behavioral, and computational approaches are reviewed in some detail, discussed, and interrelated. The authors describe experiments required to answer specific questions and relates them to new terminologies and current theoretical schemes.
This book provide useful information in the area of spinal infections, particularly with regard to those that receive delayed treatment. The book first deals with various spinal infections and their manifestations. It is strong in the areas of tuberculosis and the structural problems that ensue when spinal infections are not diagnosed and treated early. Structural diagrams are helpful. Apart from surgical techniques, adequate emphasis has been laid on clinical features, value of modern diagnostic facilities and appropriate drug therapy. This book will be a useful reference book with more infor.
The Constitution in the Supreme Court: The Second Century traces the development of the Supreme Court from Chief Justice Fuller (1888-1910) to the retirement of Chief Justice Burger (1969-1986). Currie argues that the Court's work in its second century revolved around two issues: the constitutionality of the regulatory and spending programs adopted to ameliorate the hardships caused by the Industrial Revolution and the need to protect civil rights and liberties. Organizing the cases around the tenure of specific chief justices, Currie distinguishes among the different methods of constitutional exegesis, analyzes the various techniques of opinion writing, and evaluates the legal performance of different Courts. "Elegant and readable. Whether you are in favor of judicial restraint or judicial activism, whatever your feelings about the Warren Court, or the Renquist Court, this is a book that justifies serious study."—Robert Stevens, New York Times Book Review
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