Orlando Guntinas-Lichius's Books

Axonal Branching and Recovery of Coordinated Muscle Activity after Transsection of the Facial Nerve in Adult Rats

By: Doychin N. Angelov,Orlando Guntinas-Lichius,Konstantin Wewetzer,Wolfram Neiss,Michael Streppel

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Axonal Branching and Recovery of Coordinated Muscle Activity after Transsection of the Facial Nerve in Adult Rats

By: Doychin N. Angelov,Orlando Guntinas-Lichius,Konstantin Wewetzer,Wolfram Neiss,Michael Streppel

Facial nerve surgery inevitably leads to partial pareses, abnormally associated movements and pathologically altered reflexes. The reason for this "post-paralytic syndrome" is the misdirected reinnervation of targets, which consists of two major components. First, due to malfunctioning axonal guidance, a muscle gets reinnervated by a "foreign" axon, that has been misrouted along a "wrong" fascicle. Second, the supernumerary collateral branches emerging from all transected axons simultaneously innervate antagonistic muscles and cause severe impairment of their coordinated activity. Since it is hardly possible to influence the first major component and improve the guidance of several thousands axons, the authors concentrated on the second major component and tried to reduce the collateral axonal branching.

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Page Count

140

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3540299319

ISBN 13

9783540299318

The Cerebral Perivascular Cells

By: Doychin N. Angelov,Michael Walther,Michael Streppel,Orlando Guntinas-Lichius,Wolfram F. Neiss

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The Cerebral Perivascular Cells

By: Doychin N. Angelov,Michael Walther,Michael Streppel,Orlando Guntinas-Lichius,Wolfram F. Neiss

Following an exhaustive literature review on the global issue of intracerebral presentation of antigen, this monograph summarizes results from voluminous work to establish which indigenous cerebral cells might present (auto)antigen to the immune system and thus initiate an (auto)immune reaction. Employing the combination of (a) a lesion model in which neuronal degeneration and neuronophagia are caused without disruption of the blood--brain barrier, (b) stable labeling of the neuronophages via phagocytosis of the permanent nontoxic fluorescent marker Fluoro-Gold from preloaded neurons, and (c) immunocytochemical identification of all FG-labeled brain neuronophages, the authors provide evidence that the only cells in the rat CNS which can be regarded as the resident antigen presenting cells of the brain are perivascular cells.

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Page Count

141

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3642722512

ISBN 13

9783642722516

Facial Nerve Disorders and Diseases: Diagnosis and Management

By: Orlando Guntinas-Lichius,Barry Schaitkin

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Facial Nerve Disorders and Diseases: Diagnosis and Management

By: Orlando Guntinas-Lichius,Barry Schaitkin

This authoritative and up-to-date reference is a complete guide to the basic science, diagnosis, testing, and treatment of facial nerve disorders and diseases. An international team of renowned experts, put together and headed by the book's two specialist editors, provide in-depth discussion of facial nerve topography and physiology, as well as the broad spectrum of infectious, inflammatory, acute, chronic, benign, and malignant diseases related to facial nerve dysfunction. The book is filled with practical evidence-based information, guidelines, and algorithms presented in uniformly structured chapters, allowing readers to quickly pinpoint key details for treating a specific disease or disorder. Special Features: Pertinent topics including facial nerve trauma, Lyme disease, postoperative facial nerve palsy, face transplant, adjuvant treatment with botulinum toxin and fillers, facial dystonia and facial spasms, and the psychological and medicolegal aspects of facial nerve care are covered Step-by-step descriptions provided for facial nerve repair and reconstruction, static and dynamic reanimation techniques for adults and children, evaluation and treatment of paralytic eyelids, and more A wealth of clinically relevant information, including tips and tricks, and pitfalls to avoid in everyday practice More than 260 images and 16 videos (accessed through the Thieme MediaCenter) help visualizing and comprehending the content Extensive reference lists at the end of each chapter offer an overview of scientific work on the topic With current perspectives from leading experts, valuable clinical tools and advice, and coherently organized chapters, Facial Nerve Disorders and Diseases: Diagnosis and Management is a single-volume source for the state-of-the-art in facial nerve care. Specialists and residents in otorhinolaryngology, maxillofacial surgery, plastic surgery, neurosurgery, neurology, and rehabilitation medicine will refer to the book time and again in their treatment of patients with facial nerve dysfunction.

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Page Count

1006

Publisher

Thieme

Published Date

ISBN 10

3132581542

ISBN 13

9783132581548

Book's by Orlando Guntinas-Lichius

Axonal Branching and Recovery of Coordinated Muscle Activity after Transsection of the Facial Nerve in Adult Rats

Axonal Branching and Recovery of Coordinated Muscle Activity after Transsection of the Facial Nerve in Adult Rats

The Cerebral Perivascular Cells

The Cerebral Perivascular Cells

Facial Nerve Disorders and Diseases: Diagnosis and Management

Facial Nerve Disorders and Diseases: Diagnosis and Management

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