Two very topical research questions are addressed in this book: Which are the determinants of new business formation and their survival, and will business start-ups, especially in the service sector, create employment and thereby generate growth? The analysis is based on a unique dataset consisting of the population of all businesses with at least one employee under social security in Germany in all private industries (manufacturing and services).
The idea of the book is to provide a comprehensive overview of computational physics methods and techniques, that are used for materials modeling on different length and time scales. Each chapter first provides an overview of the physical basic principles which are the basis for the numerical and mathematical modeling on the respective length-scale. The book includes the micro-scale, the meso-scale and the macro-scale. The chapters follow this classification. The book will explain in detail many tricks of the trade of some of the most important methods and techniques that are used to simulate materials on the perspective levels of spatial and temporal resolution. Case studies are occasionally included to further illustrate some methods or theoretical considerations. Example applications for all techniques are provided, some of which are from the author’s own contributions to some of the research areas. Methods are explained, if possible, on the basis of the original publications but also references to standard text books established in the various fields are mentioned.
This textbook focuses on the management challenges of founding a new venture and managing its rapid growth as the firm evolves. It covers crucial management areas in the entrepreneurship context such as entrepreneurial finance, marketing, and human resource management. Also, more hands-on management topics like writing a business plan and choosing a legal form for a venture are covered. A key chapter of the book is dedicated to leadership challenges in managing rapidly growing young firms located in new industries and technology areas. The book is written from a Continental European perspective to cater for its European target audience in entrepreneurship courses to be held in English.
The ever growing number of application scenarios for IT systems leads to a significant increase in their number and hence to a level of complexity that has grown tremendously in comparison with early IT installations by the mid of the past decade. In numerous attempts to integrate these diverging application stacks, various prominent methods have emerged in the past, most recently the topic of EAI which strives to achieve a consolidated view at diverse application systems. However, the emergence and rise of cloud-based services leads to new challenges to deal with. Usage of offerings from a no further specified cloud appears appealing for IT decision makers since it promises cost savings while even enhancing flexibility to quickly respond to changing market needs. To further support this idea, this work focuses on the aspect of inter-organisational networks that are characterised by short setup times and short time to market in order to achieve innovative products emerging from the cooperation between different actors. In this context, proper backing by dedicated ICT components is one of the key challenges. This book therefore demonstrates how portal systems, acting as intermediary between providers and consumers, can be embedded into networked enterprises by providing seamless access to all relevant information. To achieve this, this book presents a generic architecture that can serve as a blueprint for future implementations for the type of enterprise portals introduced previously and focuses on integration of external services in a user-centric manner, concentrating on the user and his specific needs to achieve productivity and user satisfaction gains. Moreover, secure communication facilities allow to consider the current application and/or user context to control exchange of information between different applications integrated on the portal platform.
This book provides clear and concise guidance for clinicians when they encounter a patient with psychosis, starting with the medical work-up to arrive at a diagnosis and ending with the comprehensive care for patients with established schizophrenia. It covers the optimal use of medications (emphasizing safe use) but also addresses other treatment approaches (psychological treatments, rehabilitation) and the larger societal context of care, including how to work effectively in complex systems. It uniquely condenses the literature into teaching points without simplifying too much, effectively serving as a learning tool for trainees and professionals. For this second edition, the book was extensively updated and its content expanded, with new figures as well. Each chapter begins with an initial summary and includes Tips and Key Points in text boxes. Each chapter also includes links to external websites and additional readings. The book contains clinical and practical wisdom for clinicians who are treating real patients at the front lines, setting it apart from all other texts. Psychotic Disorders is an excellent resource for medical students, early career professionals such as trainees and fellows, and related clinicians seeking additional training and resources, including those in psychiatry, psychology, neurology, and all others.
Due to the dramatic increase in competition over the last few years, it has become more and more important for Internet Service Providers (ISPs) to run an efficient business and offer an adequate Quality of Service. The Competitive Internet Service Provider is a comprehensive guide for those seeking to do just that. Oliver Heckmann approaches the issue from a system point of view, looking not only at running a network, but also at connecting the network with peering and transit partners or planning the expansion of the network. The Competitive Internet Service Provider: Offers an advanced reference on the topic, drawing on state-of-the art research in network technology. Clearly defines the criteria enabling ISPs to operate with the greatest efficiency and deliver adequate Quality of Service. Discusses the implications of the future multiservice Internet and multimedia applications such as Voice over IP, peer-to-peer, or network games. Delivers a comparative evaluation of different feasible Quality of Service approaches. Explores scientific methods such as queuing theory, network calculus, and optimization theory. Illustrates concepts throughout with mathematical models and simulations. This invaluable reference will provide academic and industrial researchers in the field of network and communications technology, graduate students on telecommunications courses, as well as ISP managers, engineers and technicians, equipment manufacturers and consultants, with an understanding of the concepts and issues involved in running a successful ISP.
This updated and revised second edition examines the conceptualisation and evolution of peace in International Relations (IR) theory. The book examines the concept of peace and its usage in the main theoretical debates in IR, including realism, liberalism, constructivism, critical theory, and post-structuralism, as well as in the more direct debates on peace and conflict studies. It explores themes relating to culture, development, agency, and structure, not just in terms of representations of IR, and of peace, but in terms of the discipline of IR itself. The work also specifically explores the recent mantras associated with liberal and neoliberal versions of peace, which appear to have become foundational for much of the mainstream literature and for doctrines for peace and development in the policy world. Analysing war has often led to the dominance – and mitigation – of violence as a basic assumption in, and response to, the problems of IR. This study aims to redress this negative balance by arguing that the discipline offers a rich basis for the study of peace, which has advanced significantly over the last century or so. It also proposes innovative theoretical dimensions of the study of peace, with new chapters discussing post-colonial and digital developments. This book will be of great interest to students of peace and conflict studies, politics, and IR.
This unique book presents an approach to viewing trauma. It examines the cellular consequences of trauma at a molecular level and provides new insights into the treatment of traumatic injury, based on cellular responses. The current of trauma research is reviewed, previously unpublished information on the topic is presented, and research directions are included.
Oncology in general has seen vast advancements over recent years. Improved und- standing of tumor biology, multidisciplinary team decisions and an individualized therapy are cornerstones of treatment planning for cancer patients today. These dev- opments have challenged the imaging community with ever more specifc questions on tumor detection, staging and therapy control. Whereas this evolution applies to many tumor entities, rectal cancer takes an outstanding role, as it was the recognition of certain anatomical and pathological features of the disease, with the help of magnetic resonance imaging (MRI), that induced radiology not only to aid in disease mana- ment, but in fact to be a powerful engine for new concepts in rectal cancer treatment. The continuous improvement of highly specialized MRI and the groundbreaking scientifc contributions of radiologists all over the world have paved the way for s- stantial refnements of this technique during the last decade. Consequently, dedicated imaging protocols for routine diagnostic work-up of r- tal cancer patients are now available, which can guide multidisciplinary team de- sions and, in combination with optimized surgery and chemoradiotherapy, lead to longer survival and a better quality of life. Besides the scientifc advances, the enduring clinical success of MRI in the feld of rectal cancer is highly contingent upon expertise. To this end, ongoing education and continuous training are vital.
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