This text covers the fundamentals of thermodynamics required to understand electrical power generation systems and the application of these principles to nuclear reactor power plant systems. It is not a traditional general thermodynamics text, per se, but a practical thermodynamics volume intended to explain the fundamentals and apply them to the challenges facing actual nuclear power plants systems, where thermal hydraulics comes to play. Written in a lucid, straight-forward style while retaining scientific rigor, the content is accessible to upper division undergraduate students and aimed at practicing engineers in nuclear power facilities and engineering scientists and technicians in industry, academic research groups, and national laboratories. The book is also a valuable resource for students and faculty in various engineering programs concerned with nuclear reactors. This book also: Provides extensive coverage of thermal hydraulics with thermodynamics in nuclear reactors, beginning with fundamental definitions of units and dimensions, thermodynamic variables, and the Laws of Thermodynamics progressing to sections on specific applications of the Brayton and Rankine cycles for power generation and projected reactor systems design issues Reinforces fundamentals of fluid dynamics and heat transfer; thermal and hydraulic analysis of nuclear reactors, two-phase flow and boiling, compressible flow, stress analysis, and energy conversion methods Includes detailed appendices that cover metric and English system units and conversions, detailed steam and gas tables, heat transfer properties, and nuclear reactor system descriptions
Immunoinformatics of Cancers: Practical Machine Learning Approaches Using R takes a bioinformatics approach to understanding and researching the immunological aspects of malignancies. It details biological and computational principles and the current applications of bioinformatic approaches in the study of human malignancies. Three sections cover the role of immunology in cancers and bioinformatics, including databases and tools, R programming and useful packages, and present the foundations of machine learning. The book then gives practical examples to illuminate the application of immunoinformatics to cancer, along with practical details on how computational and biological approaches can best be integrated.This book provides readers with practical computational knowledge and techniques, including programming, and machine learning, enabling them to understand and pursue the immunological aspects of malignancies. - Presents the knowledge researchers need to apply computational techniques to immunodeficiencies - Provides the most practical material for bioinformatics approaches to the immunology of cancers - Gives straightforward and efficient explanations of programming and machine learning approaches in R - Includes details of the most useful databases, tools, programming packages and algorithms for immunoinformatics - Illuminates clear explanations with practical examples of immunoinformatic approaches to cancer
This text covers the fundamentals of thermodynamics required to understand electrical power generation systems and the application of these principles to nuclear reactor power plant systems. It is not a traditional general thermodynamics text, per se, but a practical thermodynamics volume intended to explain the fundamentals and apply them to the challenges facing actual nuclear power plants systems, where thermal hydraulics comes to play. Written in a lucid, straight-forward style while retaining scientific rigor, the content is accessible to upper division undergraduate students and aimed at practicing engineers in nuclear power facilities and engineering scientists and technicians in industry, academic research groups, and national laboratories. The book is also a valuable resource for students and faculty in various engineering programs concerned with nuclear reactors. This book also: Provides extensive coverage of thermal hydraulics with thermodynamics in nuclear reactors, beginning with fundamental definitions of units and dimensions, thermodynamic variables, and the Laws of Thermodynamics progressing to sections on specific applications of the Brayton and Rankine cycles for power generation and projected reactor systems design issues Reinforces fundamentals of fluid dynamics and heat transfer; thermal and hydraulic analysis of nuclear reactors, two-phase flow and boiling, compressible flow, stress analysis, and energy conversion methods Includes detailed appendices that cover metric and English system units and conversions, detailed steam and gas tables, heat transfer properties, and nuclear reactor system descriptions
Therapeutic cancer vaccines represent a type of active cancer immunotherapy. Clinicians, scientists, and researchers working on cancer treatment require evidence-based and up-to-date resources relating to therapeutic cancer vaccines. Vaccines for Cancer Immunotherapy provides a reference for cancer treatment for clinicians and presents a well-organized resource for determining high-potential research areas. The book considers that this promising modality can be made more feasible as a treatment for cancer. Chapters cover cancer immunology, general approaches to cancer immunotherapy, vaccines, tumor antigens, the strategy of allogeneic and autologous cancer vaccines, personalized vaccines, whole-tumor antigen vaccines, protein and peptide vaccines, dendritic cell vaccines, genetic vaccines, candidate cancers for vaccination, obstacles to developing therapeutic cancer vaccines, combination therapy, future perspectives and concluding remarks on therapeutic cancer vaccines. - Introduces the feasible immunotherapeutic vaccines for patients with different types of cancer - Presents the status of past and current vaccines for cancer treatment - Considers advantages and disadvantages of different therapeutic cancer vaccines - Looks at the combination of vaccines and other modalities, including immunotherapeutic and conventional methods - Analyzes obstacles to development of therapeutic cancer vaccines - Gives a view on future perspectives in the application of therapeutic cancer vaccines
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