Nidhi Singal's Books

Disability, Poverty and Education

By: Nidhi Singal

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Disability, Poverty and Education

By: Nidhi Singal

This book is a succinct and distinctive presentation of current research addressing educational issues in relation to children and young people with disabilities in Southern contexts. Even though people with disabilities are disproportionately over-represented in the majority world, there is a lack of texts which bring together empirical insights highlighting the unique socio-economic and cultural realities of these contexts and the ways in which these have shaped developments in education. This book provides a comprehensive and critical overview of a range of issues, such as the dilemmas in conceptual translations, analysis of international aid and national policies, evaluation of various educational interventions, and issues interrogating the purpose of education. Bringing together various research projects conducted in eight different countries, this book successfully captures a unique spread of cross-cultural issues. It was originally published as a special issue of the International Journal of Inclusive Education.

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Page Count

315

Publisher

Routledge

Published Date

ISBN 10

1317850157

ISBN 13

9781317850151

Disability, Poverty and Education

By: Nidhi Singal

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Disability, Poverty and Education

By: Nidhi Singal

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N/A

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Page Count

315

Publisher

Routledge

Published Date

ISBN 10

1317850157

ISBN 13

9781317850151

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

By: Surendra Nimesh,Ramesh Chandra,Nidhi Gupta

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Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

By: Surendra Nimesh,Ramesh Chandra,Nidhi Gupta

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. - Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies - Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. - Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field

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Page Count

258

Publisher

Woodhead Publishing

Published Date

ISBN 10

0081005636

ISBN 13

9780081005637

Book's by Nidhi Singal

Disability, Poverty and Education

Disability, Poverty and Education

Disability, Poverty and Education

Disability, Poverty and Education

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

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