One of the most active and productive areas of biological science in the past decade has been the study of the biochemical and biophysical prop erties of cell membranes. There is little doubt that membranes are essen tial components of all cellular systems and that each type of membrane manifests specific and characteristic cellular functions. In the nervous system, important events such as neurotransmission, receptor binding, ion transport, axonal transport, and cell uptake are all known to take place within the neural cell membrane. Phospholipids, one of the major components of membranes, not only provide the membrane with its structural integrity and physical proper ties, but also play an important role in regulating membrane function. Attention has recently been focused on the asymmetric localization of these molecules, the identification of discrete metabolic pools of phospholipids within the membrane matrix, and their involvement in sig nal transmission. Although synaptic membranes generally lack an active mechanism for the de novo biosynthesis of phospholipids, a number of enzymic routes are present for their interconversions and for facilitating metabolic turnover. Metabolites generated during the interconversion reactions may also exert a great influence in modulating membrane func tions. The phosphogylcerides of neural membranes are especially enriched in polyunsaturated fatty acids. However, only very small amounts of these fatty acids are present in the free form, and they are maintained in dynamic equilibrium with the membrane phospholipids.
First published around 1573, and known as the "earliest; most trustworthy account" of the Reformation in England. Contains a variety documentation that defies description, like the revelation that proposes Anne Boleyn, Henry VIII's second "wife," was actually his illegitimate daughter. Later finished by Fr. Rishton, the whole ghastly story of the Protestant revolt in England—with all its unsavory characters—is told through 1587 and the murder of Mary Queen of Scots (rightful heir to the throne) under Elizabeth I.
This is an immensely readable and engaging book, which would have been an enormous resource for me as a practitioner and as a manager of social workers, earlier on in my career. It is written in a succinct, authentic, and clear style with practical examples throughout ... Joanna Nicolas brings her commitment to learning from practice alive in this book, drawing on personal examples. Her clarity on issues, such as the legal position of social workers, is excellent." Penny Thompson, Chief Executive of the General Social Care Council (GSCC) "For anyone immersed in child protection, there is a requirement to be aware, alert and assertive and to be inquisitive, intrigued, inquiring and imaginative about what children are experiencing when you are not there. These are the powerful messages from this strongly practice-focussed text with its emphasis on 'how to do it'. There is clear guidance, and powerful examples, for those still learning their craft and significant reminders for those who are more experienced. There is no more important work than protecting very vulnerable children. This book will help us all do it better." Ray Jones, Professor of Social Work, Kingston University and St George's, University of London, UK and previously Director of Social Services in Wiltshire, UK. "This book is a gem. Filled with numerous practice-based examples and laced with contemporary, 'real-world' dilemmas, it gently encourages practitioners involved in child protection work to think about their work. Whatever their level of knowledge and experience, this book offers excellent, hands-on advice from someone who, clearly, has much experience with families. But what Joanna Nicolas also brings is humanity and a real concern for people: no mean achievement!" David Shemmings, Professor of Child Protection Research, University of Kent and Royal Holloway, University of London, UK "I wish this book had been written when I was a student health visitor. It provides excellent practical guidance ... It was pleasing to see acknowledgement of the importance of trusting instinct and 'hunches' and the guidance on preparation for the home visit is invaluable ... The author's very human, honest and self-effacing approach to writing this book is refreshing. Joanna Nicolas helps you believe that you can work effectively in this field, no matter now daunted you may be." Mandy J Brimble, School of Nursing and Midwifery Studies, Cardiff University, UK Conducting a home visit is a fundamental part of a social worker's role, but in practical terms many key issues are overlooked during social work training. Part of a new Social Work Pocketbooks series, this is a practical guide to conducting home visits, a task which many feel unprepared for and is fraught with difficulties. Useful features include: Real case examples Realistic solutions to the everyday difficulties you face Examples of what to say Reference to topical research including the Munro Review of Child Protection findings Written by an experienced social worker, this book is clear, straight-forward and jargon-free. It will also be a useful aid to any professionals required to do home visiting. The book addresses: What you need to do to prepare for the visit How to get in the door What to do when you are in the home What you need to look out for How to keep yourself safe
Whether already experienced with hedge funds or just thinking about investing in them, readers need a firm understanding of this unique investment vehicle in order to achieve maximum success. Hedge Funds unites over thirty of the top practitioners and academics in the hedge fund industry to provide readers with the latest findings in this field. Their analysis deals with a variety of topics, from new methods of performance evaluation to portfolio allocation and risk/return matters. Although some of the information is technical in nature, an understanding and applicability of the results as well as theoretical developments are stressed. Filled with in-depth insight and expert advice, Hedge Funds helps readers make the most of this flexible investment vehicle.
Identifying the most serious challenges faced in child protection work, this practical guide offers helpful solutions for frontline professionals working with children and adults. Informed by her many years on the frontline and subsequent experience writing serious case reviews, Joanna Nicolas has identified the most common pitfalls in child protection cases. The book focuses on understanding the impact of neglect, information sharing between professionals, communication with children, working with non-compliance/disguised compliance, and the impact of multiple risk factors. It offers tips for overcoming the challenges of everyday practice, such as home visits, as well as enhancing understanding of the key issues in this complex field. The evidence-informed chapters are packed with case examples and include useful reminders of the underlying principles at play. This is essential reading for social workers, health care workers, mental health workers, education professionals and related professions, such as housing and probation.
A first-of-its-kind deep dive into Steven Spielberg's decades-long career, covering everything from early short films and television episodes to each of his more than 30 feature length-films. Organized chronologically and covering every short film, television episode, and blockbuster movie that Steven Spielberg has ever directed, Steven Spielberg All the Films draws upon years of research to tell the behind-the-scenes stories of how each project was conceived, cast, and produced; from the creation of the costumes to the search for perfect locations; details about Spielberg's work with longtime collaborators like George Lucas, producer Kathleen Kennedy, and composer John Williams; and of course, the direction of some of Hollywood's most memorable scenes. Spanning more than fifty years, this book details the creative processes that resulted in numerous classic films like E.T. the Extra-Terrestrial, Jaws, Jurassic Park, The Color Purple, Schindler's List, and Saving Private Ryan (to name just a few). Newer work like Lincoln, The Post, and The Fabelmans is also featured alongside awards stats, original release dates, box office totals, casting details, and other insider scoops that will keep fans turning pages. Celebrating one of cinema's most iconic artists, Steven Spielberg All the Films is the authoritative guide to the man who invented the Hollywood blockbuster.
Most people outside of the art world view art as something that is foreign to their experiences and everyday lives. A People’s Art History of the United States places art history squarely in the rough–and–tumble of politics, social struggles, and the fight for justice from the colonial era through the present day. Author and radical artist Nicolas Lampert combines historical sweep with detailed examinations of individual artists and works in a politically charged narrative that spans the conquest of the Americas, the American Revolution, slavery and abolition, western expansion, the suffragette movement and feminism, civil rights movements, environmental movements, LGBT movements, antiglobalization movements, contemporary antiwar movements, and beyond. A People’s Art History of the United States introduces us to key works of American radical art alongside dramatic retellings of the histories that inspired them. Stylishly illustrated with over two hundred images, this book is nothing less than an alternative education for anyone interested in the powerful role that art plays in our society.
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