This timely volume addresses the areas of pathophysiology and therapy of pulmonary hypertension, which have seen exciting developments over the past decade. The discoveries of endothelin overexpression as well as prostacyclin and nitric oxide deficiency in association with pulmonary hypertension have led to important therapeutic insights. The new therapies have led to significant improvements in patient function, quality of life and survival. In this book, expert authors describe these new therapies. It will be of interest not only to cardiologists, pulmonary specialists and rheumatologists, but also many nurses and pharmacotherapists.
This book constitutes the refereed proceedings of the 5th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2009, held in Nice, France in June 2009. The 54 revised full papers presented were carefully reviewed and selected from numerous submissions. The contributions cover topics such as cardiac imaging and electrophysiology, cardiac architecture imaging and analysis, cardiac imaging, cardiac electrophysiology, cardiac motion estimation, cardiac mechanics, cardiac image analysis, cardiac biophysical simulation, cardiac research platforms, and cardiac anatomical and functional imaging.
Summarizing state-of-the-art developments in long-term mechanical ventilation use, this comprehensive treatise reviews the applications, complications, and care of breathing disorders affecting the growing population of ventilation-assisted individuals-including neuromuscular and chronic obstructive pulmonary diseases (COPD) and chest wall deformit
This book probes the dynamics of academic research and scholarship evaluation. Readers will learn about scholarly metric evolution, impact factors, disruptive technologies, and a myriad of forces affecting policy development at institutions through an examination of widely-used measurements and growing concerns about their influence.
From #1 New York Times bestselling author Nicholas Perricone– respected physician, award-winning research scientist, and trusted expert on health and beauty–comes the biggest breakthrough in weight loss since Atkins. Millions of women and men have restored youthful radiance, smoothness, and suppleness to their skin through Dr. Nicholas Perricone’s advice, care, and transformative eating plan–and all with the welcome yet unexpected benefit of losing excess weight along with the wrinkles! Building on this discovery, Dr. Perricone breaks new ground with his trademark anti-inflammatory program based on the foods, supplements, and lifestyle changes with the proven ability to accelerate fat loss by increasing metabolism and building and maintaining muscle mass. Consider this staggering fact: As we age, we can expect to gain ten pounds of fat and lose five pounds of muscle each decade. In three easy steps, Dr. Perricone shows how to fight this weight gain and rebuild muscle mass, and avoid the haggard, aging, and drawn appearance that results from other weight-loss programs. Inside The Perricone Weight-Loss Diet discover • the rejuvenating and slimming secrets of the anti-inflammatory diet • which foods, supplements, and lifestyle changes enable us to lose fat while maintaining muscle • how to control hormones such as insulin and cortisol to lose weight • how to maintain youthful, firm, and radiantly toned skin on the face and body during weight loss As an added bonus, as you follow Dr. Perricone’s program you’ll sleep better, have more energy and less stress, and experience greater mental clarity without the food cravings. Lose the weight, the wrinkles, and the years!
This text contains A-Z biographical listings of 1300 individuals worldwide, setting out their qualifications, affiliations, academic background, work experience, awards and distinctions, specialist interests and publications. Details are also given of their specialist expertise and language abilities, their availability for consultation, and full addresses and contact numbers. Fully cross-referenced indexes enable the user to find individuals by both country and specialist expertise.
“This superb book is timely and is written with great attention paid to detail, particularly in its referencing of the literature. The book has a wonderful blend of theory and code (MATLAB®) so will be useful both to nonexperts and to experts in the field.” — Alan Laub, Professor, University of California, Los Angeles The only book devoted exclusively to matrix functions, this research monograph gives a thorough treatment of the theory of matrix functions and numerical methods for computing them. The author's elegant presentation focuses on the equivalent definitions of f(A) via the Jordan canonical form, polynomial interpolation, and the Cauchy integral formula, and features an emphasis on results of practical interest and an extensive collection of problems and solutions. Functions of Matrices: Theory and Computation is more than just a monograph on matrix functions; its wide-ranging content—including an overview of applications, historical references, and miscellaneous results, tricks, and techniques with an f(A) connection—makes it useful as a general reference in numerical linear algebra.Other key features of the book include development of the theory of conditioning and properties of the Fréchet derivative; an emphasis on the Schur decomposition, the block Parlett recurrence, and judicious use of Padé approximants; the inclusion of new, unpublished research results and improved algorithms; a chapter devoted to the f(A)b problem; and a MATLAB® toolbox providing implementations of the key algorithms.Audience: This book is for specialists in numerical analysis and applied linear algebra as well as anyone wishing to learn about the theory of matrix functions and state of the art methods for computing them. It can be used for a graduate-level course on functions of matrices and is a suitable reference for an advanced course on applied or numerical linear algebra. It is also particularly well suited for self-study. Contents: List of Figures; List of Tables; Preface; Chapter 1: Theory of Matrix Functions; Chapter 2: Applications; Chapter 3: Conditioning; Chapter 4: Techniques for General Functions; Chapter 5: Matrix Sign Function; Chapter 6: Matrix Square Root; Chapter 7: Matrix pth Root; Chapter 8: The Polar Decomposition; Chapter 9: Schur-Parlett Algorithm; Chapter 10: Matrix Exponential; Chapter 11: Matrix Logarithm; Chapter 12: Matrix Cosine and Sine; Chapter 13: Function of Matrix Times Vector: f(A)b; Chapter 14: Miscellany; Appendix A: Notation; Appendix B: Background: Definitions and Useful Facts; Appendix C: Operation Counts; Appendix D: Matrix Function Toolbox; Appendix E: Solutions to Problems; Bibliography; Index.
Delirium, stupor and coma are common clinical states that confront clinicians in almost every medical specialty. With appropriate diagnosis and treatment, coma can often be treated successfully. Conversely, delay in diagnosis and treatment may be lethal. This monograph provides an update on the clinical approach that was laid out in the previous 3 editions. It describes an approach for the physician at the bedside to diagnose and treat alterations of consciousness, based on pathophysiologic principles. The book begins with a description of the physiology of consciousness and the pathophysiology of disorders of consciousness. It continues with a description of the approach to a patient with a disorder of consciousness, emphasizing the bedside examination, but including the use of modern imaging techniques. The important structural and metabolic causes of coma are reviewed in detail. It then describes the emergency treatment, both medical and surgical, of patients with specific disorders of consciousness and their prognosis. New chapters describe the approach to the diagnosis of brain death and the clinical physiology of the vegetative state and minimally conscious state, as well as the ethics of dealing with such patients and their families. The book is aimed at medical students and residents, in fields from internal medicine and pediatrics to emergency medicine, surgery, neurology, neurosurgery, and psychiatry, who are likely to encounter patients with disordered states of consciousness. It includes historical background and basic neurophysiology that is important for those in the clinical neurosciences, but also lays out a practical approach to the comatose patient that is an important part of the repertoire of all clinicians who provide emergency care for patients with disorders of consciousness.
Total Knee Arthroplasty: Medical and Biomedical Engineering and Science Concepts provides an extensive overview of the most recent advancements in total knee arthroplasty (TKA) through a thorough review of the literature in medicine, engineering, and technology. Coverage includes the most recent engineering and computing techniques, such as robotics, biomechanics, artificial intelligence (AI), deep learning (DL), machine learning (ML), and optimization, as well as the medical and surgical aspects of pre-existing conditions, surgical procedure types, surgical complications, patient care, and psychological factors. This book will be a valuable introduction to TKA concepts and advances for academics, students, and researchers.
Olynthus, an ancient city in northern Greece, was preserved in an exceptionally complete state after its abrupt sacking by Phillip II of Macedon in 348 B.C., and excavations in the 1920s and 1930s uncovered more than a hundred houses and their contents. In this book Nicholas Cahill analyzes the results of the excavations to reconstruct the daily lives of the ancient Greeks, the organization of their public and domestic space, and the economic and social patterns in the city. Cahill compares the realities of daily life as revealed by the archaeological remains with theories of ideal social and household organization espoused by ancient Greek authors. Describing the enormous variety of domestic arrangements, he examines patterns and differences in the design of houses, in the occupations of owners, and in the articulations between household and urban economies, the value of land, and other aspects of ancient life throughout the city. He thus challenges the traditional view that the Greeks had one standard household model and approach to city planning. He shows how the Greeks reconciled conflicting demands of ideal and practice, for instance between egalitarianism and social inequality or between the normative roles of men and women and roles demanded by economic necessities. The book, which is extensively illustrated with plans and photographs, is supported by a Web site containing a database of the architecture and finds from the excavations linked to plans of the site.
Irish Theatre in the Twenty-First Century is the first in-depth study of the subject. It analyses the ways in which theatre in Ireland has developed since the 1990s when emerging playwrights Martin McDonagh, Conor McPherson, and Enda Walsh turned against the tradition of lyrical eloquence with a harsh and broken dramatic language. Companies such as Blue Raincoat, the Corn Exchange, and Pan Pan pioneered an avant-garde dramaturgy that no longer privileged the playwright. This led to new styles of production of classic Irish works, including the plays of Synge, mounted in their entirety by Druid. The changed environment led to a re-imagining of past Irish history in the work of Rough Magic and ANU, plays by Owen McCafferty, Stacey Gregg, and David Ireland, dramatizing the legacy of the Troubles, and adaptations of Greek tragedy by Marina Carr and others reflecting the conditions of modern Ireland. From 2015, the movement #WakingTheFeminists led to a sharpened awareness of gender. While male playwrights showed a toxic masculinity on the stage, a generation of female dramatists including Carr, Gregg, and Nancy Harris gave voice to the experiences of women long suppressed in conservative Ireland. For three separate periods, 2006, 2016, 2020-2, the author served as one of the judges for the Irish Times Irish Theatre Awards, attending all new productions across the island of Ireland. This allowed him to provide the detailed overview of the 'state of play' of Irish theatre in each of those times which punctuate the book as one of its most innovative features. Drawing also on interviews with Ireland's leading theatre makers, Grene provides readers with a close-up understanding of Irish theatre in a period when Ireland became for the first time a fully modernized, secular, and multi-ethnic society.
Single mothers face unique economic challenges, which have persisted despite women's gains in higher education and the workplace. Drawing on forty years of data from two national surveys, Nicholas H. Wolfinger and Matthew McKeever explore the contradictions that lie at the heart of single motherhood. They find that some single mothers are doing better even as others have fallen through the cracks. Providing an in-depth look into the economics of single motherhood, Thanks for Nothing offers the most detailed statistical portrait of single mothers to date and, importantly, provides concrete suggestions for how policymakers should respond to persisting inequalities among mothers.
This study investigates the adaptation and purpose-built construction of the vessels used by the Federal government to conduct riverine warfare on the waters of the American Mississippi River drainage basin. The study concentrates on the technology, geography, hydrography, and convention which shaped the construction of the vessels comprising the Federal Western Gunboat Flotilla; an organization which after October 1862 became the United States Navy Mississippi Squadron. The ability of an organization to adapt is equipment to conditions encountered during wartime is often a contributing factor in ultimate victory or defeat. During the Civil War, the process adopted by the Navy to adapt and furnish vessels for its riverine force was flawed. This study emphasizes these facts and explores the response of the Navy chain of command to lessons learned in combat about the vulnerabilities of the vessels of the Western Gunboat Flotilla. The study is not intended as a treatise on tactics or the organization of the United States Navy. However, it does address both with regard to their effect on the performance and adaptation of the vessels of the Western Gunboat Flotilla.
Includes more than 75 photos, maps and plans This particular book is about Marines during the first stage of Operation Iraqi Freedom (OIF). It spans the period from 11 September 2001 to March and April 2003, when the Coalition removed Saddam Hussein from power, and concludes in November 2003 when the Marines left Kuwait to return to their home bases in the U.S.. While many then believed that the “kinetic” phase of the fighting in Iraq was largely over, as we now know, it was only a prelude to a longer but just as deadly phase of operations where Marines would be redeployed to Iraq in 2004 to combat insurgents (both foreign and domestic) who had filtered back into the country. However, this phase of the fighting would be very different from the one the Marines and U.S. Army had fought in the spring of 2003 in the march up to take Baghdad. The primary focus of the book is I Marine Expeditionary Force (I MEF)-the run-up to the war in 2002 and early 2003, especially the development of “the plan,” with its many changes, the exhaustive rehearsals, and other preparations, and then the conduct of decisive combat operations and the immediate postwar period, mostly under the control of the U.S. Central Command’s Coalition Forces Land Component Command. The book also touches upon other Marine activities in the Military Coordination and Liaison Command in northern Iraq and with the British in the south. Nonetheless, the primary focus remains on I Marine Expeditionary Force and the interactions of its constituent elements. Other forthcoming History Division publications will soon offer detailed narratives on Marines in Operation Enduring Freedom (OEF) in Afghanistan and II MEF operations inside Iraq.
The Later Medieval City, 1300-1500, the second part of David Nicholas's ambitious two-volume study of cities and city life in the Middle Ages, fully lives up to its splendid precursor, The Growth of the Medieval City. (Like that volume it is fully self-sufficient, though many readers will want to use the two as a continuum.) This book covers a much shorter period than the first. That traced the rise of the medieval European city system from late Antiquity to the early fourteenth century; this offers a portrait of the fully developed late medieval city in all its richness and complexity. David Nicholas begins with the economic and demographic realignments of the last two medieval centuries. These fostered urban growth, raising living standards and increasing demand for a growing range of urban manufactures. The hunger for imports and a shortage of coin led to sophisticated credit mechanisms that could only function through large cities. But, if these changes brought new opportunities to the wealthy, they also created a growing problem of urban poverty: violence became endemic in the later medieval city. Moreover, although more rebellions were sparked by taxes than by class conflict, class divisions were deepening. Most cities came to be governed by councils chosen from guild-members, and most guilds were dominated by merchants. The landowning elite that had dominated the early medieval cities of the first volume still retained its prestige, but its wealth was outstripped by the richer merchants; while craftsmen, who had little political influence, were further disadvantaged as access to the guilds became more restricted. The later medieval cities developed permanent bureaucracies providing a huge range of public services, and they were paid for by sophisticated systems of taxation and public borrowing. The survival of their fuller, richer records allow us not only to apply a more statistical approach, but also to get much closer, to the splendours and squalors of everyday city-life than was possible in the earlier volume. The book concludes with a set of vibrant chapters on women and children and religious minorities in the city, on education and culture, and on the tenor of ordinary urban existence. Like its predecessor, this book is massively, and vividly, documented. Its approach is interdisciplinary and comparative, and its examples and case studies are drawn from across Europe: from France, England, Germany, the Low Countries, Iberia and Italy, with briefer reviews of the urban experience elsewhere from Baltic to Balkans. The result is the most wide-ranging and up-to-date study of its multifaceted subject. It is a formidable achievement.
This volume of essays examines the development of political and legal thinking regarding the use of force in international relations. It provides an analysis of the rules on the use of force in the political, normative and factual contexts within which they apply and assesses their content and relevance in the light of new challenges such as terrorism, weapons of mass destruction and cyber-attacks. The volume begins with an overview of the ancient and medieval concepts of war and the use of force and then concentrates on the contemporary legal framework regulating the use of force as moulded by the United Nations Charter and state practice. In this regard it discusses specific issues such as the use of force by way of self-defence, armed reprisals, forcible reactions to terrorism, the use of force in the cyberspace, humanitarian intervention and the responsibility to protect. This collection of previously published classic research articles is of interest to scholars and students of international law and international relations as well as practitioners in international law.
World of our Making is a major contribution to contemporary social science. Now reissued in this volume, Onuf’s seminal text is key reading for anyone who wishes to study modern international relations. Onuf understands all of international relations to be a matter of rules and rule in foreign behaviour. The author draws together the rules of international relations, explains their source, and elaborates on their implications through a vast array of interdisciplinary thinkers such as Kenneth Arrow, J.L. Austin, Max Black, Michael Foucault, Anthony Giddens, Jurgen Habermas, Lawrence Kohlberg, Harold Lasswell, Talcott Parsons, Jean Piaget, J.G.A. Pocock, John Roemer, John Scarle and Sheldon Wolin.
Largely reorganised and much expanded in this second edition, Practice and Procedures brings together in a single volume general methods of pain assessment and presents the wide range of therapies that can be provided by a range of health care disciplines. Authored by a multidisciplinary team of experts, chapters can stand alone for readers looking
Largely reorganised and much expanded in this second edition, Practice and Procedures brings together in a single volume general methods of pain assessment and presents the wide range of therapies that can be provided by a range of health care disciplines. Authored by a multidisciplinary team of experts, chapters can stand alone for readers looking for a general overview of the methods of techniques for pain management available to them or work to complement chapters in the preceeding three volumes, providing practical procedures and applications in the management of acute, chronic and cancer pain. The book is divided into three parts. Part One covers the principles of measurement and diagnosis, including history taking and examination, the selection of pain measures, diagnostic tests and novel imaging techniques. Part Two discusses the full range of therapeutic protocols available, from pharmacological therapies, through psychological techniques, physical therapy and international procedures, to techniques specific to pain assessment and management in paediatric patients. Part Three provides information on planning, conducting, analysing and publishing clinical trials, with invaluable guidance on the techniques of systematic review and meta-analysis in pain research. Part Four considers the role of multidisciplinary pain management teams, their organization, their place within different health care systems, and how best to manage change when implementing such a service. Part Five concludes the volume, investigating the use of guidelines, standards and quality improvement initiatives in the management of post-operative pain, and discussing the expert medicolegal report.
In this sequel to their acclaimed The Dominant Ideology Thesis, the authors develop their analysis of the social and cultural underpinnings of modern capitalism. They confront a central assumption of western culture: namely, that the individual is sovereign, and that capitalism above all other economic forms depends on individualism. These ideas have an unbroken history from Alexis de Tocqueville to Milton Friedman. The paradox of the modern world is that the moral emphasis on the individual is contradicted by the actual organization of economy and society. The authors suggest that individualism and capitalism have no enduring or necessary relationship. Their linkage is entirely accidental and was confined to one particular historical period in the West. Against the background of what they term the Discovery of the Individual, the authors show how individualism gave capitalism a particular shape, and capitalism in turn highlighted the possessive features of the individual. Oriental capitalism and late capitalism in the West bear no particular relationship to individualism; indeed, they flourish best in the absence of individualistic culture. Collectivism increasingly dominates both economic and social life. These issues once informed the sociological enterprise, but have not been systematically addressed in recent times. This book revives the classical tradition of the historical and comparative analysis of culture and economy in capitalist society, in the context of the late twentieth-century world.
In this volume leading international scholars elaborate upon the central issues of the analysis of ideology: the nature of dominant ideologies. The ways in which ideologies are transmitted; their effects on dominant and subordinate social classes in different societies; the contrast between individualistic and collectivist belief systems; and the diversity of cultural forms that coexist within the capitalist form of economic organization. This book is distinctive in its empirical and comparative approach to the study of the economic and cultural basis of social order, and in the wide range of societies that it covers. Japan, Germany and the USA constitute the core of the modern global economy, and have widely differing historical roots and cultural traditions. Argentina and Australia are white settler societies on the periphery of the capitalist world-system and as a result have certain common features, that are cut across in turn by social and political developments peculiar to each. Britain after a decade of Thatcherism is an interesting test of the efficacy of an ideological project designed to change the cultural values of a population. Poland shows the limitations of the imposition of a state socialist ideology, and the cultural complexities that result.
This is a major new handbook that covers hundreds of subjects that cross numerous industry sectors; however, the handbook is heavily slanted to oil and gas environmental management, control and pollution prevention and energy efficient practices. Multi-media pollution technologies are covered : air, water, solid waste, energy. Students, technicians, practicing engineers, environmental engineers, environmental managers, chemical engineers, petroleum engineers, and environmental attorneys are all professionals who will benefit from this major new reference source. The handbook is organized in three parts. Part A provides an extensive compilation of abbreviations and concise glossary of pollution control and engineering terminology. More than 400 terms are defined. The section is intended to provide a simple look-up guide to confusing terminology used in the regulatory field, as well as industry jargon. Cross referencing between related definitions and acronyms are provided to assist the user. Part B provides physical properties and chemical safety information. This part is not intended to be exhaustive; however it does provide supplemental information that is useful to a number of the subject entries covered in the main body of the handbook. Part C is the Macropedia of Subjects. The part is organized as alphabetical subject entries for a wide range of pollution controls, technologies, pollution prevention practices and tools, computational methods for preparing emission estimates and emission inventories and much more. More than 100 articles have been prepared by the author, providing a concise overview of each subject, supplemented by sample calculation methods and examples where appropriate, and references. Subjects included are organized and presented in a macropedia format to assist a user in gaining an overview of the subject, guidance on performing certain calculations or estimates as in cases pertinent to preliminary sizing and selection of pollution controls or in preparing emissions inventories for reporting purposes, and recommended references materials and web sites for more in-depth information, data or computational tools. Each subject entry provides a working overview of the technology, practice, piece of equipment, regulation, or other relevant issue as it pertains to pollution control and management. Cross referencing between related subjects is included to assist the reader to gain as much of a practical level of knowledge.
Progress in genetic knowledge is profoundly affecting medical practice, and no clinical specialty has more diseases associated with genetic mutations than neurology. As a more complete picture of the genes which give rise to neurological disease is obtained, trainee and practising neurologists need a guide to basic principles and the more important clinical entities with a genetic component. It is against this background that Neurogenetics: A Guide for Clinicians has been written. The book opens with coverage of genetic testing and counselling. Subsequent chapters discuss genetic factors for all the major neurological diseases, including epilepsy, Alzheimer's disease, Parkinsonism and muscular dystrophies. No book in this field can hope to be fully up to date with the latest research; rather this work provides a framework on which to add new genetic discoveries. Neurogenetics: A Guide for Clinicians provides a synoptic overview for neurologists, medical geneticists and scientists working in the field.
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