Why does a piano sound like a piano? A similar question can be asked of virtually all musical instruments. A particular note-such as middle C-can be produced by a piano, a violin, a clarinet, and many other instruments, yet it is easy for even a musically untrained listener to distinguish between these different instruments. A central quest in the study of musical instruments is to understand why the sound of the "same" note depends greatly on the instrument, and to elucidate which aspects of an instrument are most critical in producing the musical tones characteristic of the instrument. The primary goal of this book is to investigate these questions for the piano. The explanations in this book use a minimum of mathematics, and are intended for anyone who is interested in music and musical instruments. At the same time, there are many insights relating physics and the piano that will likely be interesting and perhaps surprising for many physicists.
Why does a piano sound like a piano? A similar question can be asked of virtually all musical instruments. A particular note-such as middle C-can be produced by a piano, a violin, a clarinet, and many other instruments, yet it is easy for even a musically untrained listener to distinguish between these different instruments. A central quest in the study of musical instruments is to understand why the sound of the "same" note depends greatly on the instrument, and to elucidate which aspects of an instrument are most critical in producing the musical tones characteristic of the instrument. The primary goal of this book is to investigate these questions for the piano. The explanations in this book use a minimum of mathematics, and are intended for anyone who is interested in music and musical instruments. At the same time, there are many insights relating physics and the piano that will likely be interesting and perhaps surprising for many physicists.
New advances in neuroscience promise innovations in national security, especially in the areas of law enforcement, intelligence collection, and armed conflict. But ethical questions emerge about how we can, and should, use these innovations. This book draws on the open literature to map the development of neuroscience, particularly through funding by the Defense Advanced Research Projects Agency, in certain areas like behavior prediction, behavior modification, and neuroenhancement, and its use in the creation of novel weapons. It shows how advances in neuroscience and new technologies raise ethical issues that challenge the norms of law enforcement, intelligence collection, and armed conflict, broadly grouped under the term "national security." Increasing technological sophistication without attention to ethics, this book argues, risks creating conditions for the development of "dual-use" technologies that may be prone to misuse, are grounded in an incomplete understanding of the brain, or are based on a limited view of the political contexts in which these technologies arise. A concluding section looks at policy and regulatory options that might promote the benefits of emerging neuroscience, while mitigating attendant risks. Key Features: First broad survey of the ethics of neuroscience as it applies to national security Innovative ethical analysis over a range of cross-cutting technologies including behavior prediction and modification tools, human enhancement, and novel lethal and nonlethal weapons Ethical analysis covering all stages from the development, testing, and use (or misuse) of these technologies; and decisions from the individual scientist to the nation state Strong policy focus at multiple levels, from self-governance to international regulation Combination of philosophical analysis with grounded, practical recommendations
This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.
An argument for the centrality of rights in health security, and how to apply ethical principles to protecting those rights during public health crises. In recent years, efforts to respond to infectious diseases have been described in terms of national and global security, leading to the formation of the field of “health security.” In War on All Fronts, Nicholas G. Evans provides a novel theory of just health security and its relation to the practice of conventional public health. Using COVID-19 as a jumping-off point to examine wider issues, including how the US thinks about and prepares for pandemics, Evans shows the flaws in using the “war metaphor" and how any serious understanding of health security must square with human rights—even when a disease poses a threat to national security. Evans asks what ethical principles justify declaring, and taking action during, a public health emergency such as the ongoing COVID-19 pandemic. The relevant principles, he argues, parallel those of the ethics of armed conflict. Just war theory, properly understood, begins with pacifism and a commitment to the right not to be killed and then steps back to ask under what limited conditions it is permissible to kill. In a similar way, a just health security must also begin with the idea that public health should hold human rights sacrosanct and then ask under what limited conditions other concerns might prevail. Evans’s overall goal is to formulate a guide to action, particularly as the world deals with the fallout of the COVID-19 pandemic. Turning to the transition from war back to peace in public health, he looks at reparation, rebuilding, and the accountability of actors during the crisis.
Master the fundamental concepts of physics with COLLEGE PHYSICS: REASONING AND RELATIONSHIPS. The theme of Reasoning and Relationships is reinforced throughout the book, helping you master these concepts, apply them to solve a variety of problems, and appreciate the relevance of physics to your career and your everyday life. By understanding the reasoning behind problem solving, you learn to recognize the concepts involved, think critically about them, and move beyond merely memorizing facts and equations.
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