This new volume of the Biopsy Interpretation Series is a practical, superbly illustrated reference on the primary non-lymphoid neoplasms of the skin. The book offers guidelines on how and when to biopsy the skin and then discusses benign melanocytic proliferations, precursor lesions to melanoma, and melanomas. Also included are discussions of basal cell carcinoma, squamous cell carcinoma and its precursors, benign and malignant adnexal neoplasms, and soft tissue neoplasms of the skin and superficial subcutis. A major highlight of the book is the extensive discussion of differential diagnostic considerations and their separation from the main diagnostic entities under consideration. The book features nearly 300 full-color images. A companion Website will provide 400 additional figures, plus a test bank that is ideal for board exam preparation.
“There’s still time to change things.”—Siri Hustvedt, The Blazing World Addiction is easy to fall into and hard to escape. It destroys the lives of individuals, and has a devastating cost to society. The National Institute of Health estimates seventeen million adults in the United States are alcoholics or have a serious problem with alcohol. At the same time, the country is seeing entire communities brought to their knees because of opioid additions. These scourges affect not only those who drink or use drugs but also their families and friends, who witness the horror of addiction. With Out of the Wreck I Rise, Neil Steinberg and Sara Bader have created a resource like no other—one that harnesses the power of literature, poetry, and creativity to illuminate what alcoholism and addiction are all about, while forging change, deepening understanding, and even saving lives. Structured to follow the arduous steps to sobriety, the book marshals the wisdom of centuries and explores essential topics, including the importance of time, navigating family and friends, relapse, and what Raymond Carver calls “gravy,” the reward that is recovery. Each chapter begins with advice and commentary followed by a wealth of quotes to inspire and heal. The result is a mosaic of observations and encouragement that draws on writers and artists spanning thousands of years—from Seneca to David Foster Wallace, William Shakespeare to Patti Smith. The ruminations of notorious drinkers like John Cheever, Charles Bukowski, and Ernest Hemingway shed light on the difficult process of becoming sober and remind the reader that while the literary alcoholic is often romanticized, recovery is the true path of the hero. Along with traditional routes to recovery—Alcoholics Anonymous, out-patient therapy, and intensive rehabilitation programs—this literary companion offers valuable support and inspiration to anyone seeking to fight their addiction or to a struggling loved one. Featuring Charles Bukowski, John Cheever, Dante, Ricky Gervais, Ernest Hemingway, Billie Holiday, Anne Lamott, John Lennon, Haruki Murakami, Anaïs Nin, Mary Oliver, Samuel Pepys, Rainer Maria Rilke, J. K. Rowling, Patti Smith, Kurt Vonnegut, and many more.
If a student researcher had only one handbook on their bookshelf, Miller and Salkind′s Handbook would certainly have to be it. With the updated material, the addition of the section on ethical issues (which is so well done that I′m recommending it to the departmental representative to the university IRB), and a new Part 4 on "Qualitative Methods", the new Handbook is an indispensable resource for researchers." --Dan Cover, Department of Sociology, Furman University " I have observed that most instructors want to teach methodology "their way" to imbue the course with their own approach; Miller-Salkind allows one to do this easily. The book is both conceptually strong (e.g., very good coverage of epistemology, research design and statistics) and at the same time provides a wealth of practical knowledge (scales, indices, professional organizations, computer applications, etc.) In addition, it covers the waterfront of methodology." --Michael L. Vasu, Director of Information Technology, North Carolina State University "A unique and excellent reference tool for all social science researchers, and a good textbook for graduate students and senior year undergraduate classes. These students are about to enter the real life of research, and need a handy and comprehensive tool as a starting point that offers shortcuts for getting into real research projects. For a small project, the book offers enough information to get the project started. For big projects, the book is ideal for information on where to look for things and examples." --Jianhong Liu, Department of Sociology, Rhode Island College The book considered a "necessity" by many social science researchers and their students has been revised and updated while retaining the features that made it so useful. The emphasis in this new edition is on the tools graduate students and more advanced researchers need to conduct high quality research. Features/Benefits: Provides step-by-step instruction for students′ research training by beginning with how to find a creative idea, a middle-range theory, and initial hypothesis and proceeds through design, proposal, collection and analysis of data followed by writing, reporting and publication Section on scales and indices are organized so that readers can quickly locate and find the type of scale or index in which they may be interested All sections are now followed by useful and well-considered reference sections so that readers can read more about each topic Includes updated coverage on new scales, internal and external validity, and new analytic techniques with extensive references on each Presents extensive coverage of how to prepare manuscripts for publication, including a list of all journals covered by Sociological Abstracts along with the editorial office address and URL for each entry Discusses the importance of policy research with presentation and discussion of specific models as an adjunct to both applied and basic research techniques Provides extensive coverage of funding opportunities including those offered by the National Institutes of Health, the National Science Foundation, and a directory of private funding sources including relevant contact information New to this edition: New Part 4 by John Creswell and Ray Maietta provides a comprehensive introduction to qualitative methods including a review of existing computer applications for collecting and analyzing data New and more current reviews and commentaries have replaced dated or no longer relevant excerpts Thousands of new references on the assessment of important sociological variables as well as references to such topics as statistical analysis, computer applications, and specific topics Thoroughly updated information on the use of computers and online research techniques, including beginning and intermediate material about the Internet and its use by the modern research scientist Coherent and thoughtful review of the most popular statistical analysis software packages New guidelines and discussion of ethical practices in social and behavioral science research, including extensive coverage of institutional review board procedures and activities Expansion of social indicators to include international coverage Plus, there is an extensive and well-organized table of contents with four levels of headings; and, for the first time in the history of the book, a comprehensive index.
A large number of cardiovascular diseases are accompanied by inflammation. This volume on the molecular basis of microcirculatory disorders gives a comprehensive summary of key steps in the inflammatory cascade. Leading investigators present a state-of-the-art analysis of the molecular determinants of leukocyte-endothelial cell adhesion, mechanotransduction in endothelial and inflammatory cells, mechanisms of cell activation, microvascular apoptosis with applications to ischemia-reperfusion in the brain, the heart and in venous disease, diabetes and hypertension. The book provides the latest thinking in these important cardiovascular problems, with the most contemporary literature and a look at the increasingly complex events during inflammation. Molecular biology tools, microvascular and modern bioengineering analysis are seamlessly integrated into the analysis of clinical problems. The book helps not only newcomers to gain entry into the interesting problems associated with microvascular disorders, but lays the foundation for the design of new therapeutic interventions.
This book discusses advanced statistical methods that can be used to analyse ecological data. Most environmental collected data are measured repeatedly over time, or space and this requires the use of GLMM or GAMM methods. The book starts by revising regression, additive modelling, GAM and GLM, and then discusses dealing with spatial or temporal dependencies and nested data.
Throughout the history of Byzantium 65 emperors were dethroned and only 39 reigns ended peacefully. How might a usurper get away with murdering his predecessor? And how could a bloody act of regicide lead to one of the most glorious of all eras in Byzantium? These were questions that puzzled Michael Psellos as he looked back at Basil I’s assassination of Michael III and the origin of the Macedonian dynasty. Might the imperial art of Basil, his sons and grandson help to explain how the dynasty overcame its violent beginnings and secured the loyalty of its subjects? It has long been recognised that the early Macedonian emperors were active propagandists but royal art has usually been viewed thematically over the span of centuries. Official iconography has been understood to project imperial power in ways which were impersonal and unchanging. This book instead adopts a chronological approach and considers how Basil justified his seizure of power, and how his successors went on to articulate their own ideas about authority. It concludes that imperial art did at times reflect the personality of the emperor and the political demands of the moment, such as the need for an heir, the nature of court politics or the choice of successor. This innovative account of the forging of the Macedonian dynasty will appeal to those interested in how early medieval kings and emperors used art to create their own image, to differentiate themselves from rivals and to extend the boundaries of their personal power.
Anyone Can Learn to Invest Wisely With This Bestselling Investment System! Through every type of market, William J. O'Neil's national bestseller How to Make Money in Stocks has shown over 2 million investors the secrets to successful investing. O'Neil's powerful CAN SLIM Investing System--a proven seven-step process for minimizing risk and maximizing gains--has influenced generations of investors. Based on a major study of all the greatest stock market winners from 1880 to 2009, this expanded edition gives you: Proven techniques for building stocks before they make big price gains Tips on picking the best stocks, mutual funds, and ETFs to maximize your gains 100 new charts to help you spot today's profitable trends Strategies to help you avoid the most common investor mistakes! The CAN SLIM Investing System The American Association of Individual Investors 12-year study of over 50 leading investment strategies found O'Neil's CAN SLIM System to be the top-performing strategy. CAN SLIM produced 2,763.3% over the 12 years vs. 14.9% for the S&P 500. Includes the Investor’s Business Daily’s Video Action Plan—an introduction to IBD’s winning investment strategies, PLUS new high-resolution charts you can zoom in on Complete Investing System-You Get Started in Three Easy Steps: ACTIVATE YOUR eIBD SUBSCRIPTION You'll get one month of access to the tools and features in eIBD and investors.com to help you apply what you learn in How to Make Money in Stocks Get your first month of eIBD now at investors.com/system. Then, watch the Video Action Plan that gives you a quick overview for using eIBD. REGISTER FOR YOUR LIVE INVESTING WORKSHOP At this three-hour workshop, IBD experts will give you an overview of the CAN SLIM System and provide an action plan for using key features and investing tools. Call 1-800-831-2525 to register for the workshop nearest you. READ HOW TO MAKE MONEY IN STOCKS This book gives you the foundation for your investing success, so be sure to read each chapter carefully. Follow these three steps and you'll be on the path to being a more successful investor. You Can Do It, Too! "I figured I made more money in stocks using IBD as my daily resource than I've made as a CPA over the last 10 years." -- Robert F., Illinois, CPA "This system has helped me find the big winners in a market rally, and more importantly, it has helped me avoid the big losses in a market downturn." -- Michael A., Florida, retired
An unprecedented book on option pricing! For the first time, the basics on modern option pricing are explained ``from scratch'' using only minimal mathematics. Market practitioners and students alike will learn how and why the Black-Scholes equation works, and what other new methods have been developed that build on the success of Black-Shcoles. The Cox-Ross-Rubinstein binomial trees are discussed, as well as two recent theories of option pricing: the Derman-Kani theory on implied volatility trees and Mark Rubinstein's implied binomial trees. Black-Scholes and Beyond will not only help the reader gain a solid understanding of the Balck-Scholes formula, but will also bring the reader up to date by detailing current theoretical developments from Wall Street. Furthermore, the author expands upon existing research and adds his own new approaches to modern option pricing theory. Among the topics covered in Black-Scholes and Beyond: detailed discussions of pricing and hedging options; volatility smiles and how to price options ``in the presence of the smile''; complete explanation on pricing barrier options.
Over the years, risk management has developed separately in both the insurance and financial fields. Today, the two are finding value in each others tools and techniques. Integrated Risk Management combines the best of the two notions of risk management, insurance and financial, to develop solutions ideal for tadays complex risk environment. Tools go beyond hedging strategies to also examine leveraging, post-loss financing, contingent financing, and fiversification.
Commodity Derivatives In the newly revised Second Edition of Commodity Derivatives: Markets and Applications, expert trading educator and author Neil Schofield delivers a comprehensive overview of a wide variety of commodities and derivatives. Beginning with discussions of commodity markets generally before moving on to derivative valuation and risk management, the author then dives into individual commodity markets, like gold, base metals, crude oil, natural gas, electricity, and more. Schofield relies on his extensive experience at Barclays Investment Bank to offer readers detailed examinations of commodity finance and the use of commodities within a wider investment portfolio. The second edition includes discussions of critical new topics like dual curve swap valuation, option valuation within a negative price environment using the Bachelier model, volatility skews, smiles, smirks, term structures for major commodities, and more. You’ll find case studies on corporate failures linked to improper commodity risk management, as well as explorations of issues like the impact of growing interest in electric vehicles on commodity markets. The text of the original edition has been updated and expanded and new example transactions are included to help the reader understand the concepts discussed within. Each chapter follows a uniform structure, with typical demand and supply patterns following a non-technical description of the commodity at issue. Discussions of the physical markets in each commodity and the main exchange-traded and over-the-counter products conclude each chapter. Perfect for commodity and derivatives traders, analysts, and risk managers, the Second Edition of Commodity Derivatives: Markets and Applications will also earn a place in the libraries of students and academics studying finance and the graduate intake in financial institutions. A one-stop resource for the main commodity markets and their associated derivatives Finance professionals seeking a single volume that fully describes the major commodity markets and their derivatives will find everything they need in the latest edition of Commodity Derivatives: Markets and Applications. Former Global Head of Financial Markets Training at Barclays Investment Bank Neil Schofield delivers a rigorous and authoritative reference on a crucial, but often overlooked, subject. Completely revised and greatly expanded, the Second Edition of this essential text offers finance professionals and students coverage on every major class of commodities, including gold, steel, ethanol, crude oil, and more. You’ll also find discussions of derivative valuation, risk management, commodity finance, and the use of commodities within an investment portfolio. Non-technical descriptions of major commodity classes ensure the material is accessible to everyone while still in-depth and rigorous enough to deliver key information on an area central to global finance. Ideal for students and academics in finance, Commodity Derivatives is an indispensable guide for commodity and derivatives traders, analysts, and risk managers who seek a one-volume resource on foundational and advanced topics in commodity markets and their associated derivatives.
Mental Health is an accessible introductory textbook aimed primarily at nursing and health care students who are not in the mental health field of practice but are seeking to understand mental health and become rounded practitioners. It will also be useful as a broad introduction for mental health nursing students. Through clear explanations, examples and activities, the book will help you to recognise and support people with mental health issues whenever they are encountered in your practice. You will learn: What mental health is and how it interacts with physical health About different theories and models that are applied to understanding mental illness How to relate to and communicate with people experiencing mental health problems How to recognise the common diagnosable mental health disorders and understand the treatments and interventions that are applied to them About the impact that mental health issues can have on people at different stages of life, from childhood to adulthood and later life How to apply legal and ethical frameworks and to assess risk when supporting people with mental health issues. Written by a team of highly experienced mental health academics and practitioners, this book will help you to develop the underpinning knowledge and skills you need and to apply them in your own field of practice. Pre-publication reviews “Accessible and thorough, and definitely well pitched for non-mental health clinicians.” Senior Lecturer, Mental Health Nursing “From an adult nursing point of view it’s got everything I would expect it to cover.” Adult nursing student "The book is very readable and accessible, I like the tone of the text as it is informative, and the activities give you chance to reflect.... The information is comprehensive without being too wordy, but academically sound. This book should be on the reading list for all nursing students and other HCP students. It should also be on the book shelf in all nursing offices, [social worker] offices, occupational health etc..” Mental health nursing student “I would definitely recommend this book to non-specialists. I like the breadth of areas that the book covers.” Senior Lecturer, Mental Health Nursing Essentials is a series of accessible, introductory textbooks for students in nursing, health and social care. New and forthcoming titles in the series: The Care Process Communication Skills Leadership Learning Disabilities Mental Health Promoting Health and Wellbeing Research and Evidence-Based Practice Study Skills
This textbook describes the biomechanics of bone, cartilage, tendons and ligaments. It is rigorous in its approach to the mechanical properties of the skeleton yet it does not neglect the biological properties of skeletal tissue or require mathematics beyond calculus. Time is taken to introduce basic mechanical and biological concepts, and the approaches used for some of the engineering analyses are purposefully limited. The book is an effective bridge between engineering, veterinary, biological and medical disciplines and will be welcomed by students and researchers in biomechanics, orthopedics, physical anthropology, zoology and veterinary science. This book also: Maximizes reader insights into the mechanical properties of bone, fatigue and fracture resistance of bone and mechanical adaptability of the skeleton Illustrates synovial joint mechanics and mechanical properties of ligaments and tendons in an easy-to-understand way Provides exercises at the end of each chapter
The UK government’s reforms of the NHS and public health system require partnerships if they are to succeed. Those partnerships concerned with public health are especially important and are deemed to be a ’good thing’ which add, rather than consume, value. Yet the significant emphasis on partnership working to secure effective policy and service delivery exists despite the evidence testifying to how difficult it is to make partnerships work or achieve results. Partnership working in public health presents the findings from a detailed study of public health partnerships in England. The lessons from the research are used to explore the government’s changes in public health now being implemented, most of which centre on new partnerships called Health and Wellbeing Boards that have been established to work differently from their predecessors.The book assesses their likely impact and the implications for the future of public health partnerships. Drawing on systems thinking, it argues that partnerships can only succeed if they work in quite different ways. The book will therefore appeal to the public health community and students of health policy.
A thorough updating of the best-selling, vital reference and textbook on melanocytic proliferations PRAISE FOR THE FIRST EDITION: “Well-written and entertaining” —Modern Pathology “An extremely helpful guide for the practicing dermatopathologist or general pathologist” —Archives of Pathology and Laboratory Medicine “An incredibly relevant clinical-histopathologic text” —Doody’s Melanocytic proliferations comprise a large number of pigmented lesions of the skin and muscosa. Of these, melanoma is of particular interest to clinicians and their patients. The rising number of incidences of melanoma has led to increased interest in the disease from diagnostic, management, and basic science perspectives. The Melanocytic Proliferations: A Comprehensive Textbook of Pigmented Lesions is the most complete single-source treatment of the subject available—thoroughly updated to reflect the very latest studies and clinical experience in diagnosing and treating melanocytic proliferation. This new edition of the bestseller presents an experience- and evidence-based review of pigmented lesions that encompasses the biology, diagnosis, and treatment of melanocytic proliferations and disorders, including melanoma. It comes with over 300 new color images—bringing the total to over 600—and contains two completely new chapters: Dermatoscopic Diagnosis of Melanoma; and Reflectance Confocal Microscopy. Chapter coverage includes: • An approach to the clinical diagnosis of melanoma, its precursors, and its clinical mimics • Freckles and lentigines • Benign acquired nevi • Dermal dendritic melanocytic proliferations/dermal melanocytoses • Spitz nevus • Combined nevus, deep penetrating nevus, plexiform spindle cell nevus, and borderline tumors of the deep penetrating nevus variant • Recurrent melanocytic nevus • Congenital nevi • Dysplastic melanocytic nevi, de novo intradermal epithelioid and lentiginous melanocytic dysplasias, and nevi at specific anatomic sites • Melanoma • Conjunctival melanocytic proliferations • Use of adjunctive immunoperoxidase, molecular, and ultrastructural studies in the diagnosis of melanocytic proliferations • Biology of melanoma • Borderline melanocytic proliferation • Dermatoscopic diagnosis of melanoma • Reflectance confocal microscopy • Therapy of melanoma The Melanocytic Proliferations: A Comprehensive Textbook of Pigmented Lesions is an incredibly important text for all clinical pathologists, dermatopathologists, surgical pathologists, dermatologists, cosmetic physicians, and surgeons.
By identifying similarities in various books, this annual selection guide helps readers to independently choose titles of interest published in the last year.Each entry describes a separate book, listing everything readers need to know to make selections. Arranged by author within six genre sections, detailed entries provide: Title Publisher and publication dateSeriesNames and descriptions of charactersTime period and geographical settingReview citationsStory typesBrief plot summarySelected other books by the authorSimilar books by different authorsAuthor, title, series, character name, character description, time period, geographic setting and genre/sub-genre indexes are included to facilitate research.
Chronic obstructive pulmonary disease (COPD), which encompasses both chronic bronchitis and emphysema, is one of the most common respiratory conditions of adults in the developed world. Asthma and COPD: Basic Mechanisms and Clinical Management provides a unique, authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it is a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.* Highlights distinguishing features between asthma and COPD* Reviews benefits and limitations of current therapies* Summarises key information in two-colour artwork * Extensively referenced to primary literature
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