Natalia L. Komarova's Books

Targeted Cancer Treatment in Silico

Small Molecule Inhibitors and Oncolytic Viruses

By: Natalia L. Komarova,Dominik Wodarz

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Targeted Cancer Treatment in Silico

Small Molecule Inhibitors and Oncolytic Viruses

By: Natalia L. Komarova,Dominik Wodarz

Countless medical researchers over the past century have been occupied by the search for a cure of cancer. So far, they have developed and implemented a wide range of treatment techniques, including surgery, chemo- and radiotherapy, antiangiogenic drugs, small molecule inhibitors, and oncolytic viruses. However, patterns of these treatments' effectiveness remain largely unclear, and a better understanding of how cancer therapies work has become a key research goal. Cancer Treatment in Silico provides the first in-depth study of approaching this understanding by modeling cancer treatments, both mathematically and through computer simulations. The main goal of this book is to help expose students and researchers to in silico methods of studying cancer. It is intended for both the applied mathematics and experimental oncology communities, as mathematical models are playing an increasingly important role to supplement laboratory biology in the fight against cancer. Written at a level that generally requires little technical background, the work will be a valuable resource for scientists and students alike.

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Page Count

235

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1461483018

ISBN 13

9781461483014

Computational Biology of Cancer

Lecture Notes and Mathematical Modeling

By: Dominik Wodarz,Natalia L. Komarova

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Computational Biology of Cancer

Lecture Notes and Mathematical Modeling

By: Dominik Wodarz,Natalia L. Komarova

- Provides an introduction to computational methods in cancer biology - Follows a multi-disciplinary approach

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Page Count

266

Publisher

World Scientific

Published Date

ISBN 10

9812560270

ISBN 13

9789812560278

Dynamics Of Cancer: Mathematical Foundations Of Oncology

By: Dominik Wodarz,Natalia Komarova

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Dynamics Of Cancer: Mathematical Foundations Of Oncology

By: Dominik Wodarz,Natalia Komarova

The book aims to provide an introduction to mathematical models that describe the dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for advanced undergraduate or graduate courses, and also serves as a reference book for researchers. The book has a strong evolutionary component and reflects the viewpoint that cancer can be understood rationally through a combination of mathematical and biological tools. It can be used both by mathematicians and biologists. Mathematically, the book starts with relatively simple ordinary differential equation models, and subsequently explores more complex stochastic and spatial models. Biologically, the book starts with explorations of the basic dynamics of tumor growth, including competitive interactions among cells, and subsequently moves on to the evolutionary dynamics of cancer cells, including scenarios of cancer initiation, progression, and treatment. The book finishes with a discussion of advanced topics, which describe how some of the mathematical concepts can be used to gain insights into a variety of questions, such as epigenetics, telomeres, gene therapy, and social interactions of cancer cells.

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Age

Page Count

533

Publisher

World Scientific

Published Date

ISBN 10

9814566381

ISBN 13

9789814566384

Book's by Natalia L. Komarova

Targeted Cancer Treatment in Silico

Targeted Cancer Treatment in Silico

Computational Biology of Cancer

Computational Biology of Cancer

Dynamics Of Cancer: Mathematical Foundations Of Oncology

Dynamics Of Cancer: Mathematical Foundations Of Oncology

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