Randomized controlled trials are one of the most powerful and revolutionary tools of research. This book is a convenient and accessible description of the underlying principles and practice of randomized controlled trials and their role in clinical decision-making. Structured in a jargon-free question-and-answer format, each chapter provides concise and understandable information on a different aspect of randomized controlled trials, from the basics of trial design and terminology to the interpretation of results and their use in driving evidence-based medicine. The authors end each chapter with their musings, going beyond the evidence or citations, and sometimes even beyond orthodox correctness to share their thoughts and concerns about different aspects of randomized controlled trials, and their role within the health system. Updated to include insights from the last decade, this second edition challenges over-reliance on randomized controlled trials by debating their strengths and limitations and discussing their optimal use in modern healthcare. It also includes a new and increasingly relevant chapter on the ethics of randomized trials. World renowned writers and thinkers Drs Jadad and Enkin bring you this invaluable book for busy health professionals who wish to understand the theory of randomized controlled trials and their influence on clinical, research or policy decisions.
The second edition of A guide to effective care in pregnancy and childbirth will be invaluable to anyone involved in the care of pregnant women, and to expectant parents. The book is about the effects of care given and received during pregnancy and childbirth. Fifteen years ago the authors began a systematic review of the evidence. They analysed more than 7000 of the best clinical research studies, and classified the elements of care as effective, promising, not proven either way, or not worth using. The result of this work was two major publications: Effective care in pregnancy and childbirth and a regularly updated electronic database of reviews. All the main findings and conclusions of these publications are available here in an easily readable, inexpensive, and updated form. The new edition is extensively revised and rewritten, incorporating the results of the important evidence about the effects of care during pregnancy and childbirth that has accumulated since the first edition was published. The first edition received critical acclaim because its conclusions were based on sound evidence and has become a unique reference source for evaluating care policies and practices.
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