Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences A practical guide to the use of basic principles of experimental design and statistical analysis in pharmacology Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences provides clear instructions on applying statistical analysis techniques to pharmacological data. Written by an experimental pharmacologist with decades of experience teaching statistics and designing preclinical experiments, this reader-friendly volume explains the variety of statistical tests that researchers require to analyze data and draw correct conclusions. Detailed, yet accessible, chapters explain how to determine the appropriate statistical tool for a particular type of data, run the statistical test, and analyze and interpret the results. By first introducing basic principles of experimental design and statistical analysis, the author then guides readers through descriptive and inferential statistics, analysis of variance, correlation and regression analysis, general linear modelling, and more. Lastly, throughout the textbook are numerous examples from molecular, cellular, in vitro, and in vivo pharmacology which highlight the importance of rigorous statistical analysis in real-world pharmacological and biomedical research. This textbook also: Describes the rigorous statistical approach needed for publication in scientific journals Covers a wide range of statistical concepts and methods, such as standard normal distribution, data confidence intervals, and post hoc and a priori analysis Discusses practical aspects of data collection, identification, and presentation Features images of the output from common statistical packages, including GraphPad Prism, Invivo Stat, MiniTab and SPSS Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences is an invaluable reference and guide for undergraduate and graduate students, post-doctoral researchers, and lecturers in pharmacology and allied subjects in the life sciences.
Once a part of Charlestown that could only be reached via "The Neck" (present-day Sullivan Square), Somerville became accessible from Boston with the construction of the Middlesex Canal and the extension of various rail lines in the mid- to late nineteenth century. By 1842, Somerville's population had increased to the point that the town officially separated itself from Charlestown. Over the years, the population continued to grow. With the increase in population came tremendous change, including the subdivision of farms and estates for residential neighborhoods. The city of Somerville was incorporated in 1871, and the bucolic borough became the beloved hometown of many residents over the next century. Described by Mayor Edward Glines as "healthy, morally clean, comfortable and convenient," Somerville has thrived for years as an attractive, modern residential neighborhood.
Volume 2, dedicated to Barry Hawthorne, presents papers concerned with the genesis of eclogites, the mineralogy of diamond and its inclusions, exploration methods for kimberlite, the geochemistry of the upper mantle and the character of cratons.
Trying to read up on statistics can be like trying to decide where you want to start eating the elephant and what’s the most digestible way to get it down. This book is written to give bite-size nuggets of insight based on our experiences grappling with datasets large and small. It is intended to bridge the gap between the formal equations and the practicalities of generating a research manuscript. We won’t pretend reading it will answer all your questions but it will help explain what questions need to be asked for your study and how you can address them with both accuracy and clarity. The size, detail and (ostensible) organization of this book allow for easy reading and can give a leg (or at least a half-step) up for those seeking more detailed study later. Features include: Excel sheets to allow exploration of topics raised Emphasis on intuitive explanations over formulas. Consideration of issues specific to clinical and surgical studies Our audience is someone who may or may not have enjoyed formal statistics education (that is, you may have had it and not enjoyed it!) who may like seeing a more dressed-down presentation of the topics. Actual statisticians may pick this up at risk of a chuckle (with us or at us) and may find some useful ways to present topics to non-statisticians.
We are often told that mean welfare is what the public wants. Whether or not that's true, this book encourages us to at least be honest about what that entails. It explores how diverse welfare users navigate the personal and practical hurdles of Australia’s so-called social security system, where benefits are deliberately meagre and come with strings attached. Based on ethnographic fieldwork in a region of Sydney known for ethnic diversity and socio-economic disadvantage, Emma Mitchell brings her own experience of belonging to a poor family long reliant on welfare to her research. This book shows the different cultural resources that people bring to welfare encounters with a sensitivity and subtlety that are often missing in both sympathetic and cynical accounts of life on welfare.
The Aboriginal Australians first arrived on the continent at least 60,000 years ago, occupying and adapting to a range of environmental conditions—from tropical estuarine habitats, densely forested regions, open plains, and arid desert country to cold, mountainous, and often wet and snowy high country. Cultures adapted according to the different conditions and adapted again to environmental changes brought about by rising sea levels at the end of the last ice age. European colonization of the island continent in 1788 not only introduced diseases to which Aborigines had no immunity but also began an enduring and at times violent conflict over land and resources. Reconciliation between Aborigines and the settler population remains unresolved. This second edition of the Historical Dictionary of Australian Aborigines contains a chronology, an introduction, an extensive bibliography, and more than 300 cross-referenced entries on the politics, economy, foreign relations, religion, and culture of the Aborigines. This book is an excellent resource for students, researchers, and anyone wanting to know more about the indigenous people of Australia.
This is part of a series which covers the NVQ and GNVQ language options in Business, and Leisure & Tourism, and is available in French, German and Spanish. Each course comprises a student book, a resource and assessment file, two presentation cassettes and two consolidation cassettes. End-of-unit progress checks are cross-matched with NVQ criteria for assessment in reading, speaking and writing, and each of the resource files contains photocopiable worksheets and a cassette for preparation and assessment in all four skills.
A growing heterogeneity of demand, the advent of ';long tail markets';, exploding product complexities, and the rise of creative consumers are challenging companies in all industries to find new strategies to address these trends. Mass customization (MC) has emerged in the last decade as the premier strategy for companies in all branches of industry to profit from heterogeneity of demand and a broad scope of other customer demands.The research and practical experience collected in this book presents the latest thinking on how to make mass customization work. More than 50 authors from academia and management debate on what is viable now, what did not work in the past, and what lurks just below the radar in mass customization, personalization, and related fields.Edited by two leading authorities in the field of mass customization, both volumes of the book discuss, among many other themes, the latest research and insights on customization strategies, product design for mass customization, virtual models, co-design toolkits, customization value measurement, open source architecture, customization communities, and MC supply chains. Through a number of detailed case studies, prominent examples of mass customization are explained and evaluated in larger context and perspective.
Technology is changing society faster than anyone could have imagined even a few short years ago. People share intimate details to hundreds of acquaintances online, yet they are stumped when it comes to writing a simple thank-you note. They talk, text, and surf on their phones constantly but seem oblivious to the needs of the people who are right in front of them. The Complete Idiot's Guide® to Modern Manners, Fast Track, helps people navigate the uncertain waters of modern social behavior and gives them tips for overcoming the most common miserable moments they're likely to encounter. In it, readers learn how to: Make a good first impression in person, over the phone, in print, and online. Practice good table manners in a world of buffets, informal meals, and a proliferation of restricted diets. Get along with neighbors and their pets, kids, habits, and hobbies. Maintain harmony in the office despite the more casual nature of the workplace. Master the social possibilities of online networking, texting, and smartphones while avoiding embarrassing faux pas. Whip out the old-fashioned pen for written correspondence that makes an impact. Communicate comfortably in person, including small talk, defusing tense situations, and avoiding subjects that are still too uncomfortable for polite conversation. Navigate the difficult situations that arise when traveling and out on the town. Maintain genuine respect for others' differences and disabilities. Be the model of manners at celebrations of life's milestone moments, including weddings and births. Get the right answer to all gift quandaries People are busy and no longer have the time or inclination to comb through Emily Post. This quick book helps readers get the answers they need so they can get on with life.
Materials Engineering and Science Understand the relationship between processing and material properties with this streamlined introduction Materials engineering focuses on the complex and crucial relationship between the physical properties of materials and the chemical bonds that comprise them. Specifically, this field of study seeks to understand how materials can be designed to meet specific design and performance criteria. This ‘materials paradigm’ has, in recent years, become integral to numerous cutting-edge areas of technological development. Materials Engineering and Science seeks to introduce this vital and fast-growing subject to a new generation of scientists and engineers. It integrates core thermodynamic, kinetic, and transport principles into its analysis of the structural, mechanical, and physical properties of materials, creating a streamlined and intuitive approach that fosters understanding. Now fully revised to reflect the latest research and educational paradigms, this is an essential resource. Readers of the second edition will also find: Detailed discussion of all major classes of materials, including polymers, composites, and biologics New and expanded treatment of nanomaterials, additive manufacturing (3D printing), and molecular simulation Web-based and physical supplementary materials including an instructor guide, solutions manual, and sample lecture slides Materials Engineering and Science is ideal for all advanced undergraduate and early graduate students in engineering, materials science, and related subjects.
What makes Anne of Green Gables an international, time-honoured classic? International audiences have described reading L.M. Montgomery's most celebrated novel as an experience in enchantment. Balancing criticism and celebration, Jane Ledwell and Jean Mitchell bring together essays that consider the sources of the wonder that Montgomery's work inspires. The popular appeal of Montgomery's classic is undeniable, but the reasons for its worldwide resonance are less obvious. From a range of perspectives, the contributors to Anne around the World focus on the numerous themes the novel raises, showcasing why it has charmed readers across the globe - from Iran to Australia, and from Sweden to Japan. Essays consider issues of class, race, and colonial history, discuss Anne's place in children's literature, her passion for writing, and the ways in which L.M. Montgomery and her red-haired protagonist are celebrated by legions of fans. Featuring contributions from many international writers, Anne around the World traces the meaning and influence of a story that spread far from its place of origin on a small Canadian island to distant and culturally diverse places. Contributors include Yoshiko Akamatsu (Notre Dame Seishin University, Japan), Doreley Carolina Coll (University of Prince Edward Island), Brooke Collins-Gearing (School of Humanities and Social Science, New South Wales), Margaret Doody (Notre Dame University), Elizabeth R. Epperly (emeritus, University of Prince Edward Island), Barbara Carman Garner (Carleton University), Caroline E. Jones (Texas State University-San Marcos), Paul Keen (Carleton University), Jane Ledwell, Jennie MacDonald (PhD, University of Denver), Susan Meyer (Wellesley College), Jean Mitchell, Mary Henley Rubio (emeritus, University of Guelph), Gholamreza Sami (Sussex University), Wendy Shilton (University of Prince Edward Island), Cynthia Sugars (University of Ottawa), Tanfer Emin Tunc (Hacettepe University, Turkey), Åsa Warnqvist (Stockholm University, Sweden), Elizabeth Hillman Waterston (emeritus, University of Guelph), and Budge Wilson (author).
Growing up, Mykel Mitchell found more truth in the words of Run DMC than any preacher’s sermon. He saw more prosperity in the lives of local drug dealers than in the lives of neighborhood saints. It was only natural that he would gravitate toward hustling. Years later, when “the life” left him empty and he had nothing to lose, he gave Jesus Christ a chance—and he has never looked back. In Word, Mykel takes us on the personal, moving and at times humorous journey that helped him reconcile his faith in Christ, not only with his intellect and instincts—but with his passion for all things hip hop. In this refreshingly candid take on Church doctrine, he addresses questions like: “Why does God need my money?” and “What’s the big deal with sex anyway?” and explains how he came to rock baggy jeans and sports jerseys right along with his platinum cross and tattered bible, without shame or apologies.
The Complete Idiots Guide® to World War II, Second Edition, will feature updated and expanded coverage of the fateful D-Day invasion, a critical timeline of major WW II events, and a WW II timeline highlighting the crucial and most important events of the war. It will include details about major battles on land, in the air, and on the sea-starting with Hitler's rise to power and his goal of European conquest, as well as Japan's bombing of Pearl Harbor and the decisive battles such as D-Day and the Battle of the Midway, which turned they tides of the war toward the Allies.
A sparkling new series introducing five unforgettable women who flock to yoga at turning points in their lives and find the gift of lasting friendship. The yoga studio is where daily cares are set aside, mats are unfurled, and physical exertion leads to well-being, renewal, and friendship. An aggressively expanding chain of Los Angeles yoga "experience centers," has Lee and her extraordinary teaching abilities in its sights. They woo her with a lucrative contract, a trademarked name for her classes, and a place for her handsome musician husband. But accepting the contract means abandoning the students at the homey studio Lee runs in L.A.'s Silver Lake district- and leaving behind four women whose friendships are suddenly more important to her than retirement benefits and a salary increase. Tales from the Yoga Studio is an insider's look at the current obsession with yoga, told with enough humor, wit, and warmth to charm and delight readers, whether or not they've ever done a Downward Dog.
Creating Positive Elementary Classrooms: Preventing Behavior Challenges to Promote Learning includes straightforward, feasible, and evidenced-based strategies designed to prevent behavior problems in K-5 classrooms. With an exclusive classroom focus, this practitioner-friendly book encourages teachers to be proactive in classroom management and guides them through the process of setting up their classrooms to maximize learning while focusing on prevention of behavior challenges. Its emphasis on catching behavior problems before they occur enables teachers to run their classrooms more efficiently and experience less frustration, while also increasing student learning. A well-organized, systematic, and predictable teaching environment helps to prevent challenging behaviors, and this book presents ways to achieve this type of classroom environment. Using real-life classroom scenarios, this guide equips teachers with management techniques that break the common cycle of frustration, aggression, rejection, and hostility, so they can create positive elementary classrooms.
This essential handbook provides clinicians with a summary of contraindications and precautions to review before treating patients seeking physical rehabilitation. This detailed resource discusses all of the contraindications in one convenient source and includes the full range of interventions, ranging from physical agents to supportive devices to therapeutic exercises. Organized by ICD categories and referenced from multiple sources, with strong coverage of adverse events, this handbook helps to ensure safe practice. - Provides crucial, easily accessible information to refresh therapists on contraindications that may not fall within their routine area of treatment. - Covers the full range of interventions in detail, including the purpose of the intervention, mechanism, contraindications and precautions, rationale, and references. - Helps ensure that practitioners do no harm, providing safer client care and addressing clients with pre-existing conditions. - Uses terminology from The Guide to Physical Therapist Practice, reinforcing the use of up-to-date language. - Presents quality information from a highly renowned author, with evidence-based information throughout.
An A-to-Z guide to the most wholesome foods for you and your family! Get the facts about food additives, pesticides, foodborne pathogens, genetically engineered foods, irradiated foods, antibiotics and hormones, mad cow disease, trans fats, and much more! It seems that every day, food producers, government agencies, and the media make confusing, contradictory claims about which foods are safe and which are dangerous. Organized in quick-reference format, Safe Foods will help you separate the hype from the truth, find safe, healthy foods for your family, and answer some of today’s most burning questions: · Are organic fruits and vegetables actually better—and are they worth the extra expense? · If irradiating meat is safe, why have so many other countries banned it? · What do experts really know about the safety of genetically engineered foods? · How concerned should I be about the hormones, steroids, and antibiotics in my child’s diet? Take Safe Foods with you the next time you go to the supermarket—and let it do the shopping for you.
This is the inspiring story of two Gordon Highlanders Territorial Army battalions which saw action in some of the Second World War’s fiercest battles. After evacuation from Dunkirk, 6th Gordons fought in Tunisia in 1943, leading to the German surrender in North Africa. Following a spell in Iraq, the 1st London Scottish fought in Sicily and then the Battle of Monte Cassino where Private George Mitchell won his posthumous Victoria Cross, the most prestigious of the numerous gallantry awards to the men of both battalions. In January 1944, the 6th Gordons were the first British battalion ashore at Anzio. While the landing was unopposed, the Germans mounted devastating counter-attacks but, despite almost 400 killed, wounded and captured, the Battalion heroically held on. The 1st London Scottish arrived to fight alongside their Regimental ‘brethren’ suffering equally heavy devastating casualties. After the break-out, the Gordons pipe band led the liberation parade in Rome. Both battalions went on to fight up through Italy to smash the Gothic Line and eventual victory.
This volume is the final publication of the Interdisciplinary Working Group, “Psychological Thought and Practice in Historical and Interdisciplinary Perspective,” sponsored by the Berlin-Brandenburg Academy of Sciences and Humanities from October 2000 until March 2004.
There is, perhaps, no other place in the world fraught with as much turmoil as the Middle East. This updated guide provides readers with an intense look at current events and the ever-changing political and social landscape, as well as the history-ancient and modern-of the region. This latest edition of The Complete Idiot's Guide to Middle East Conflict offers a completely updated view of events in the region through the corrective lens of present-day knowledge, as well as a look at what's going on there right now- The rearming of Hezbollah, and what it may mean to Israel and the Lebanese government. The increased threat of Iran-despite increased pressure from the United States and Europe, its acquisition of nuclear weapons may only be a matter of time. With Hamas controlling Gaza and the Palestinian Authority now divided, can the Palestinians present a united position in peace talks? The evacuation from Gaza-has this peace measure only led to a launching pad for a new front in a war against Israel?
This book constitutes the refereed proceedings of the 11th International Conference on Information and Communications Security, ICICS 2009, held in Beijing, China, in December 2009. The 37 revised full papers presented together with one invited paper were carefully reviewed and selected from 162 submissions. The papers are organized in topical sections on cryptanalysis, algorithms and implemantations, public key cryptography, security applications, software security, system security, network security, database security, trust management, and applied cryptography.
This book traces the emergence and development of an organized, institutionalized Jewish social science, and explores the increasing importance of statistics and other modes of analysis for Jewish elites throughout Europe and the United States. The Zionist movement provided the initial impetus as it looked to the social sciences to provide the knowledge of contemporary Jewish life deemed necessary for nationalist revival. The social sciences offered empirical evidence of the ambiguous condition of the Jewish diaspora, and also charted emancipation and assimilation, viewed as dissolutions of and threats to Jewish identity. Liberal, assimilationist scholars also utilized social science data to demonstrate the continuing viability of Jewish life in the diaspora. Jewish social science grew out of a sustained effort to understand and explain the effects of modernization on Jewry. Above all, Jewish scholars sought to give the enormous transformations undergone by Jewry in the nineteenth century a larger meaning and significance
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