Success comes in many forms and in synthesis it can be a failure that results in their ultimate successful solutions. This long-awaited sequel to "Dead Ends and Detours" retains the proven concept while featuring over 20 new case studies of failed strategies and their (successful) solutions in natural product total synthesis. Additionally, computational models are used to discuss the problem in much more detail and to provide readers with additional information not found in the primary literature. The topics range from classic synthetic reactions (e.g. Diels Alder reaction), metal-mediated coupling reactions, metathesis, and asymmetric catalysis to the importance of protecting and activating groups. This book will benefit not only graduate students in organic chemistry but also advanced researchers as they gain knowledge derived from the step-by-step analysis of mistakes made in the past and, thus be able to improve their own chemical reaction planning. With its coverage of the most commonly applied reaction types, the book perfectly complements its predecessor, which focuses on general aspects, such as reactivity and selectivity.
Organic Reaction Mechanisms shows readers how to interpret the experimental data obtained from an organic reaction, and specifically how an organic reaction mechanism can be considered or rejected based on the analysis of the experimental evidence. Whilst examining a series of selected examples of mechanisms, the text focuses on real cases and discusses them in detail. The examples are arranged to elucidate key aspects of organic reaction mechanisms. The authors employ all the types of information that the authors of the original work considered useful and necessary, including spectroscopic data, kinetic and thermodynamic data, isotopic labelling and organic reactivity. The book makes an excellent primer for advanced undergraduates in chemistry who are preparing for exams and is also useful for graduate students and instructors.
Writing about Troilo over a century after his birth and nearly fifty years after his death implies a certainty: the artist, who performed with him, in all but a few cases, no longer exist. That vast absence compels us to seek Troilo where he never left: the music. “Troilo: Biography of Argentina” is a music book, but also a precise and rigorous painting of a mobilized, vigorous and encompassing country where culture –and tango– were in the spotlight. It might well be read as a text that uncovers the keys of growth and decline of Argentina
The historical record of the Rio Grande valley through much of the nineteenth century reveals well-documented violence fueled by racial hatred, national rivalries, lack of governmental authority, competition for resources, and an international border that offered refuge to lawless men. Less noted is the region’s other everyday reality, one based on coexistence and cooperation among Mexicans, Anglo-Americans, and the Native Americans, African Americans, and Europeans who also inhabited the borderlands. War and Peace on the Rio Grande Frontier, 1830–1880 is a history of these parallel worlds focusing on a border that gave rise not only to violent conflict but also cooperation and economic and social advancement. Meeting here are the Anglo-Americans who came to the border region to trade, spread Christianity, and settle; Mexicans seeking opportunity in el norte; Native Americans who raided American and Mexican settlements alike for plunder and captives; and Europeans who crisscrossed the borderlands seeking new futures in a fluid frontier space. Historian Miguel Ángel González-Quiroga draws on national archives, letters, consular records, periodicals, and a host of other sources to give voice to borderlanders’ perspectives as he weaves their many, varied stories into one sweeping narrative. The tale he tells is one of economic connections and territorial disputes, of refugees and bounty hunters, speculation and stakeholding, smuggling and theft and other activities in which economic considerations often carried more weight than racial prejudice. Spanning the Anglo settlement of Texas in the 1830s, the Texas Revolution, the Republic of Texas , the US-Mexican War, various Indian wars, the US Civil War, the French intervention into Mexico, and the final subjugation of borderlands Indians by the combined forces of the US and Mexican armies, this is a magisterial work that forever alters, complicates, and enriches borderlands history. Published in association with the William P. Clements Center for Southwest Studies at Southern Methodist University in Dallas, Texas
This book not only relates the defining moments of the Cuban Revolution – such as the Moncada Barracks attack, the assault on Batista’s Presidential Palace, the Bay of Pigs invasion, and the Cuban Missile Crisis – but also lesser-known events like the “War Against the Bandits”; the overseas adventures of Che Guevara in the Congo and Bolivia; Fidel Castro’s possible prior knowledge of and involvement in JFK’s assassination; Cuba’s “silent war against the environment”; and ongoing foreign intelligence operations. The book contains information most readers and academicians may not be familiar with and utilizes major tomes as sources that have only been published in Spanish and so are not widely available to international audiences outside of Spain and Latin America. It will enlighten readers about the realities of the Cuban Revolution – its purported achievements as well as its definite shortcomings; its impact on world events in the last seven decades; and correct the record where needed – enhancing the fount of knowledge for further research by social scientists, historians, and political scientists.
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