Pro Exchange 2013 SP1 PowerShell Administration is your one-stop resource for both basic and advanced administration of Exchange Server 2013 Service Pack 1 and Exchange Online, Microsoft's best-selling hosted Exchange service. The industry shift that is currently happening toward ‘the cloud’ is not just about hosting your applications somewhere else. It’s also driving automation and standardization of technical solutions, which in turn is leading to greater productivity. Embracing PowerShell will help you administer your existing environment more efficiently and also teach you valuable ‘cloud-ready’ skills as well. This book is your best-in-class companion for gaining a deep, thorough understanding of managing all facets of Exchange 2013 Service Pack 1 with PowerShell. Authors Michel de Rooij and Jaap Wesselius, both Microsoft messaging MVPs, take you through tips, tricks, and little known facts that will make your administration life simpler and more effective. Along with revealing what’s new in Exchange Server 2013, this well-paced, deeply engaging tutorial provides detailed deployment guidance, for upgraders and migrators as well as for organizations entirely new to the Exchange platform. The book details how all of the major Exchange components fit together, from SMTP messages to all kinds of clients. It also provides in-depth configuration examples with an eye toward creating scalable, reliable, and secure installations. Additionally, this guide covers the tools and techniques for monitoring an Exchange environment and troubleshooting when things go wrong. Discover how to automate time consuming management tasks, configure a Hybrid environment with an on-premises Exchange deployment, and more today with Pro Exchange 2013 SP1 PowerShell Administration. Teaches you the basics of PowerShell and provides a foundation for more advanced scripting Deploy an Office 365 tenant in hybrid mode with your existing Exchange servers Learn how to manage Exchange Online with Remote PowerShell
Most of the scholarship regarding the Dutch monk and architect Dom Hans van der Laan OSB (1904-1991) has been narrowly focused on his architectural theory and projects. The liturgical and theological dimensions have been virtually neglected, though they are vital for a proper understanding of his thought. Through a thorough reading of the original sources, including previously unexplored documents from various archives, this book takes an interdisciplinary approach to Van der Laan’s theory. It brings together the different aspects of his work by studying both the liturgical-theological and architectural elements. On this basis the book offers a synthesis of the way in which Van der Laan was able to link earthly matter to the divine Mystery.
DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylation as a potential tool for determining cancer risk, and diagnosis between benign and malignant disease. Therapies are at the heart of this volume and the possibilities of DNA demethylation. In cancer, unlike genetic mutations, DNA methylation and histone modifications are reversible and thus have shown great potential in the race for effective treatments. In addition, the authors present the importance of high-throughput methylome analysis, not only in cancer, but also in non-neoplastic diseases such as rheumatoid arthritis. - Discusses breaking biomarker research in major disease families of current health concern and research interest, including obesity, type II diabetes, schizophrenia, and autoimmunity - Summarizes advances not only relevant to cancer, but also in non-neoplastic disease, currently an emerging field - Describes wholly new concepts, including the linking of metabolic pathways with epigenetics - Provides translational researchers with the knowledge of both basic research and clinic applications of DNA methylation in human diseases
Headache syndromes rank amongst the most common presenting symptoms in general practice and neurology, affecting up to 15% of the adult population. Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Headache Syndromes provides clinicians with a definitive resource for diagnosing and managing patients with primary and secondary forms of headaches, either as isolated complaints or as part of a more complex syndrome. Split into 7 key sections with 59 chapters, this comprehensive work discusses the scientific basis and practical management of headache syndromes in a logical format. Each chapter is written by international experts in neurology who share their research and extensive experience by providing a wealth of practical advice for use in clinical situations. In addition, all content is up-to-date and chapters incorporate discussions on the latest International Classification of Headache Disorders 3rd edition when relevant.
Marine Ecology: Processes, Systems, and Impacts offers a carefully balanced and stimulating survey of marine ecology, introducing the key processes and systems from which the marine environment is formed, and the issues and challenges which surround its future conservation.
Pro Exchange 2013 SP1 PowerShell Administration is your one-stop resource for both basic and advanced administration of Exchange Server 2013 Service Pack 1 and Exchange Online, Microsoft's best-selling hosted Exchange service. The industry shift that is currently happening toward ‘the cloud’ is not just about hosting your applications somewhere else. It’s also driving automation and standardization of technical solutions, which in turn is leading to greater productivity. Embracing PowerShell will help you administer your existing environment more efficiently and also teach you valuable ‘cloud-ready’ skills as well. This book is your best-in-class companion for gaining a deep, thorough understanding of managing all facets of Exchange 2013 Service Pack 1 with PowerShell. Authors Michel de Rooij and Jaap Wesselius, both Microsoft messaging MVPs, take you through tips, tricks, and little known facts that will make your administration life simpler and more effective. Along with revealing what’s new in Exchange Server 2013, this well-paced, deeply engaging tutorial provides detailed deployment guidance, for upgraders and migrators as well as for organizations entirely new to the Exchange platform. The book details how all of the major Exchange components fit together, from SMTP messages to all kinds of clients. It also provides in-depth configuration examples with an eye toward creating scalable, reliable, and secure installations. Additionally, this guide covers the tools and techniques for monitoring an Exchange environment and troubleshooting when things go wrong. Discover how to automate time consuming management tasks, configure a Hybrid environment with an on-premises Exchange deployment, and more today with Pro Exchange 2013 SP1 PowerShell Administration. Teaches you the basics of PowerShell and provides a foundation for more advanced scripting Deploy an Office 365 tenant in hybrid mode with your existing Exchange servers Learn how to manage Exchange Online with Remote PowerShell
Use this one-stop resource for both basic and advanced administration of Exchange Server 2019 and 2016. It will help you in running an Exchange environment, whether it be 100% on-premises or a hybrid configuration with Exchange Online (as part of Office 365). This revised version is divided into four parts, describing Exchange infrastructure, upgrading Exchange server, integration with Office 365, and security and compliance. In the first part, you will go through a short introduction of Exchange server followed by its installation and configuration. You will learn client access along with Exchange mailbox and managing Exchange recipients. In the second part, you will learn how to upgrade from Exchange 2010 to 2016 and from 2013 to Exchange 2019. The third part is dedicated to the Exchange integration with Office 365, followed by the last part that teaches you how to secure your Exchange environment and its compliance. After reading this book, you will understand best practices, do’s and don’ts, and notes from the field to migrate and work on Exchange 2016 and 2019. What You Will Learn Create a highly available and redundant Exchange environment Understand security, message hygiene (CEO fraud, for example), and compliance Know the infrastructure changes in Exchange 2019 Integrate and manage hybrid recipients Who This Book Is For IT pros who are responsible for building and maintaining an Exchange environment, both on-premises and in a hybrid configuration with Exchange Online
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