Michael Tsokos's Books

Forensic Pathology Reviews

By: Michael Tsokos

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A collection of cutting-edge reviews of many of the key recent medical and legal advances in forensic science. These critical surveys concentrate on common pathological entities likely to be encountered in daily forensic routine, as well as on specific pathological conditions rarely seen in the autopsy room. Complementing rather than replacing the classic textbooks in forensic pathology, the authors explore new avenues for analyzing the pathology of burned bodies, traumatic brain injury, death by drug abuse, sudden cardiac death, sudden infant death and neonaticide, and fatalities resulting from kicking and trampling. Other areas of interest include accidental autoerotic deaths, hypothermia fatalities, injuries from resuscitation procedures, the interpretation of alcohol levels in different specimens, and the potential forensic differential diagnoses and interpretation of iliopsoas muscle hemorrhage in the light of autopsy.

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309

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1592597866

ISBN 13

9781592597864

Rheumatology

By: Marc C. Hochberg,Alan J. Silman,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman

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Rheumatology

By: Marc C. Hochberg,Alan J. Silman,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman

Consistently lauded for its comprehensiveness and full-color color presentation, the latest edition of Rheumatology by Marc C. Hochberg, MD, MPH et al. continues the tradition of excellence of previous editions. Designed to meet the needs of the practicing clinician, it provides extensive, authoritative coverage of rheumatic disease from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format covering all major disorders of the musculoskeletal system in complete, self-contained chapters. Get trusted perspectives and insights from chapters co-authored by internationally renowned leaders in the field, 25% of whom are new to this edition. Track disease progression and treat patients more effectively with the most current information, including 22 new chapters on genetic findings, imaging outcomes, and cell and biologic therapies as well as rheumatoid arthritis and SLE. Incorporate the latest findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics.

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11248

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323086322

ISBN 13

9780323086325

Forensic Pathology of Trauma

By: Michael J. Shkrum,David A. Ramsay

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Forensic Pathology of Trauma

By: Michael J. Shkrum,David A. Ramsay

The practice of forensic pathology includes the collection and analysis of evidence in relation to a corpse in order to establish the cause of death. Knowledge of the cause of death contributes to the determination of the manner of death by medical examiners and coroners, who are occasionally assisted by law enforcement officers. In the process of establishing the cause and manner of death, representatives of various investigative bodies have several responsibilities, including explaining the death to family members, attempting to reduce the risk of similar deaths in the future, and, if applicable, apprehending the individuals who are responsible for the death. The most well-known and popular role of a forensic pathologist is in the inves- gation of cases of suspicious death; however, most medicolegal autopsies involve unexpected deaths that are above suspicion, many of which are caused by trauma (trauma being defined as any physical force or agent that causes bodily harm). The purpose of Forensic Pathology of Trauma: Common Problems for the Pathologist is to provide practical advice and information about the conduct of the forensic autopsy in cases of trauma, and to offer guidance about the analysis of the autopsy findings in these cases.

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654

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Springer Science & Business Media

Published Date

ISBN 10

159745138X

ISBN 13

9781597451383

Sjogren's Syndrome, An Issue of Oral and Maxillofacial Surgery Clinics

By: Michael T Brennan

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Sjogren's Syndrome, An Issue of Oral and Maxillofacial Surgery Clinics

By: Michael T Brennan

Editor Michael Brennan highlights important areas in Sjögren’s Syndrome for all oral and maxillofacial surgeons. Topics include diagnosis and the ACR classification criteria, epidemiology and pathophysiology, salivary gland dysfunction and xerostomia, salivary gland disease: sialadenitis to lymphoma, extraglandular manifesations, oral complications, management of xerostomia, parotidectomy in Sjögren’s Syndrome, support network for Sjögren’s Syndrome patients, and much more!

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137

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Elsevier Health Sciences

Published Date

ISBN 10

0323266738

ISBN 13

9780323266734

Targeted Treatment of the Rheumatic Diseases

By: Michael H. Weisman

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Targeted Treatment of the Rheumatic Diseases

By: Michael H. Weisman

Michael H. Weisman, Michael Weinblatt, James S Louie, and Ronald Van Vollenhoven offer their unique insights into choosing the correct pharmacological and non-pharmacological therapies for your patients. Chapters cover the full breadth of rheumatic diseases, rheumatoid arthritis, lupus, connective tissue diseases, osteoporosis, regional pain disorders, and fibromyalgia. The full-color design presents detailed clinical photographs and treatment algorithms for visual guidance and easy reference. Covers the treatment of pediatric patients as well as adults so that you can properly address the particular needs of any patient you see. Features the guidance and specific recommendations of experts from United States and Europe for a state-of-the-art approach to the variety of treatments currently in use. Displays the clinical manifestations of rheumatic diseases in full color, along with treatment algorithms for easy at-a-glance reference.

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503

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Elsevier Health Sciences

Published Date

ISBN 10

141609993X

ISBN 13

9781416099932

Lonely Planet Greece

By: Lonely Planet,Korina Miller,Kate Armstrong,Alexis Averbuck,Michael S Clark,Anna Kaminski,Vesna Maric,Craig McLachlan,Zora O'Neill,Leonid Ragozin

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Lonely Planet Greece

By: Lonely Planet,Korina Miller,Kate Armstrong,Alexis Averbuck,Michael S Clark,Anna Kaminski,Vesna Maric,Craig McLachlan,Zora O'Neill,Leonid Ragozin

Lonely Planet: The world’s leading travel guide publisher Lonely Planet Greece is your passport to the most relevant, up-to-date advice on what to see and skip, and what hidden discoveries await you. Stand in the shadow of the Acropolis, compare sunsets and beaches as you hop from island to island, or sample the freshest flavours and most succulent seafood; all with your trusted travel companion. Get to the heart of Greece and begin your journey now! Inside Lonely Planet’s Greece Travel Guide: Colour maps and images throughout Highlights and itineraries help you tailor your trip to your personal needs and interests Insider tips to save time and money and get around like a local, avoiding crowds and trouble spots Essential info at your fingertips - hours of operation, phone numbers, websites, transit tips, prices Honest reviews for all budgets - eating, sleeping, sight-seeing, going out, shopping, hidden gems that most guidebooks miss Cultural insights give you a richer, more rewarding travel experience - history, art, literature, music, architecture, landscapes, wildlife, cuisine, and the Greek way of life Covers Athens, Peloponnese, Central Greece, Northern Greece, Saronic Gulf Islands, Cyclades, Crete, Dodecanese, Aegean Islands, Evia, the Sporades, Ionian Islands, and more eBook Features: (Best viewed on tablet devices and smartphones) Downloadable PDF and offline maps prevent roaming and data charges Effortlessly navigate and jump between maps and reviews Add notes to personalise your guidebook experience Seamlessly flip between pages Bookmarks and speedy search capabilities get you to key pages in a flash Embedded links to recommendations' websites Zoom-in maps and images Inbuilt dictionary for quick referencing The Perfect Choice: Lonely Planet Greece, our most comprehensive guide to Greece, is perfect for both exploring top sights and taking roads less travelled. Looking for a guide focused on just the islands? Check out Lonely Planet’s Greek Islands or Crete guides for a comprehensive look at all the islands have to offer; or Pocket Athens, a handy-sized guide focused on the can’t-miss sights for a quick trip. About Lonely Planet: Since 1973, Lonely Planet has become the world's leading travel media company with guidebooks to every destination, an award-winning website, mobile and digital travel products, and a dedicated traveller community. Lonely Planet covers must-see spots but also enables curious travellers to get off beaten paths to understand more of the culture of the places in which they find themselves. Important Notice: The digital edition of this book may not contain all of the images found in the physical edition.

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1388

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Lonely Planet

Published Date

ISBN 10

1787019497

ISBN 13

9781787019492

Reliability, Maintainability, and Supportability

Best Practices for Systems Engineers

By: Michael Tortorella

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Reliability, Maintainability, and Supportability

Best Practices for Systems Engineers

By: Michael Tortorella

Focuses on the core systems engineering tasks of writing,managing, and tracking requirements for reliability,maintainability, and supportability that are most likely to satisfycustomers and lead to success for suppliers This book helps systems engineers lead the development ofsystems and services whose reliability, maintainability, andsupportability meet and exceed the expectations of their customersand promote success and profit for their suppliers. This book isorganized into three major parts: reliability, maintainability, andsupportability engineering. Within each part, there is material onrequirements development, quantitative modelling, statisticalanalysis, and best practices in each of these areas. Heavy emphasisis placed on correct use of language. The author discusses the useof various sustainability engineering methods and techniques incrafting requirements that are focused on the customers’needs, unambiguous, easily understood by the requirements’stakeholders, and verifiable. Part of each major division of thebook is devoted to statistical analyses needed to determine whenrequirements are being met by systems operating in customerenvironments. To further support systems engineers in writing,analyzing, and interpreting sustainability requirements, this bookalso Contains “Language Tips” to help systems engineerslearn the different languages spoken by specialists andnon-specialists in the sustainability disciplines Provides exercises in each chapter, allowing the reader to tryout some of the ideas and procedures presented in the chapter Delivers end-of-chapter summaries of the current reliability,maintainability, and supportability engineering best practices forsystems engineers Reliability, Maintainability, and Supportability is a referencefor systems engineers and graduate students hoping to learn how toeffectively determine and develop appropriate requirements so thatdesigners may fulfil the intent of the customer.

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464

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119058309

ISBN 13

9781119058304

Biopsy Interpretation of the Liver

By: Michael Torbenson

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Biopsy Interpretation of the Liver

By: Michael Torbenson

This title, part of the Biopsy Interpretation Series edited by Jonathan Epstein, is a practical guide and bench reference for practicing surgical pathologists for the interpretation of liver biopsies. Each chapter follows the series format, which parallels and complements the normal diagnostic process, with key differential diagnostic features of specific tumors detailed within each category. It focuses on the practical, diagnostically useful information that is directly relevant to the practice of surgical pathology.

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813

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1469887606

ISBN 13

9781469887609

Forensic Biomechanics

By: Jules Kieser,Michael Taylor,Debra Carr

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Forensic Biomechanics

By: Jules Kieser,Michael Taylor,Debra Carr

Biomechanics is the application of mechanical principles to living organisms, and it is one of the most exciting and fastest growing research areas. In forensic science, it is biomechanics that explains trauma to the body at a crime scene or the fracture of fibers and textiles, and helps interpret blood spatter. Forensic Biomechanics is a comprehensive overview of the role of biomechanics in forensics. Well-illustrated with real-life case studies, and using a multidisciplinary approach, this unique book is an invaluable reference for practicing forensic scientists, lawyers, and researchers.

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176

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John Wiley & Sons

Published Date

ISBN 10

1119990114

ISBN 13

9781119990116

Brigham and Women's Experts' Approach to Rheumatology

By: Jonathan S. Coblyn,Michael Weinblatt,Simon Helfgott,Bonnie Bermas

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Brigham and Women's Experts' Approach to Rheumatology

By: Jonathan S. Coblyn,Michael Weinblatt,Simon Helfgott,Bonnie Bermas

Brigham and Women's Experts' Approach to Rheumatology was just honored with 4 Stars from Doody's Book Review! Rheumatic symptoms are often vague and difficult to diagnose. Brigham and Women's Experts' Approach to Rheumatology helps clinicians navigate the myriad disorders and makes recommendations for treatment—all in one concise reference book. This title is an essential guide to one of the most important fields of medicine that is often misunderstood yet increasingly relevant in primary care. This titles is for physicians in training, primary care physicians. and any healthcare professional caring for patients with rheumatologic disorders. The text features: • A guide to the newest drugs and treatments • How to differentiate between rheumatic disorders • How to recognize false positives and negatives in lab tests • Detailed plans for diagnosis and patient care

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249

Publisher

Jones & Bartlett Publishers

Published Date

ISBN 10

1449618561

ISBN 13

9781449618568

Surgical Pathology of the Liver

By: Michael Torbenson,Roger Moreira,Lizhi Zhang

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Surgical Pathology of the Liver

By: Michael Torbenson,Roger Moreira,Lizhi Zhang

Written by surgical pathologists for surgical pathologists, Surgical Pathology of the Liver focuses on sharpening your skills and knowledge in diagnostic histopathology, including laboratory and clinical findings that are directly useful when evaluating liver histology for clinical care. It offers comprehensive, superbly illustrated coverage of general liver pathology, as well as several chapters on topics that are not often included in liver pathology textbooks. Abundant high-quality illustrations have been carefully chosen to support and extend the information given in the text.

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1509

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1496397746

ISBN 13

9781496397744

Childhood 6.7

A History of Family Socialization and the Education and Schooling of the Human Being

By: Michael Hüter

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Childhood 6.7

A History of Family Socialization and the Education and Schooling of the Human Being

By: Michael Hüter

CHILDHOOD 6.7, drawing on extensive, thorough and multi-year research, ist a story of childhood and at the same time a critique of civilization. It is a passionate plea and manifesto for children to once again be allowed to grow up humanely and "species-appropriately", for a new appreciation of family socialization and for complete freedom of education. "Finally a book that brings together a wealth of arguments in such a well-founded way - the whole to demonstrate that our education system cannot go on as before. Hopefully, it will soon become reguired reading for all those responsible for child rearing and education, and favorite reading for paarents." Gerald Hüther, neurobiologist, bestselling author "Childhood 6.7" is a masterpiece that not 'only' conveys a wealth of researched realities but that also enriches them with insightful interpretations..." Hans-Joachim Maaz, psychoanalyst, bestselling author The original German edition of the book was first published in 2018 under the title "Kindheit 6.7", Edition Liberi & Mundo. It is a bestseller in Germany since Nov. 2018. For more information, visit www.michael-hueter.org

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474

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BoD – Books on Demand

Published Date

ISBN 10

3200083506

ISBN 13

9783200083509

Cells, Aging, and Human Disease

By: Michael Fossel

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Cells, Aging, and Human Disease

By: Michael Fossel

It explains both the limited and general model of cell senescence as the central component in human clinical aging."--BOOK JACKET.

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504

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Oxford University Press, USA

Published Date

ISBN 10

0195140354

ISBN 13

9780195140354

Applied Therapeutics

The Clinical Use of Drugs

By: Caroline S. Zeind,Michael G. Carvalho,Judy W. Cheng,Kathy Zaiken,Trisha LaPointe

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Applied Therapeutics

The Clinical Use of Drugs

By: Caroline S. Zeind,Michael G. Carvalho,Judy W. Cheng,Kathy Zaiken,Trisha LaPointe

50th Anniversary Edition of the groundbreaking case-based pharmacotherapy text, now a convenient two-volume set. Celebrating 50 years of excellence, Applied Therapeutics, 12th Edition, features contributions from more than 200 experienced clinicians. This acclaimed case-based approach promotes mastery and application of the fundamentals of drug therapeutics, guiding users from General Principles to specific disease coverage with accompanying problem-solving techniques that help users devise effective evidence-based drug treatment plans. Now in full color, the 12th Edition has been thoroughly updated throughout to reflect the ever-changing spectrum of drug knowledge and therapeutic approaches. New chapters ensure contemporary relevance and up-to-date IPE case studies train users to think like clinicians and confidently prepare for practice.

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6301

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1975167104

ISBN 13

9781975167103

Cells, Aging, and Human Disease

By: Michael B. Fossel M.D.

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Cells, Aging, and Human Disease

By: Michael B. Fossel M.D.

Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease. Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy. The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.

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504

Publisher

Oxford University Press

Published Date

ISBN 10

0198032196

ISBN 13

9780198032199

Greenfield's Surgery

Scientific Principles and Practice

By: Michael W. Mulholland

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Greenfield's Surgery

Scientific Principles and Practice

By: Michael W. Mulholland

Revised, updated, and enhanced from cover to cover, the Sixth Edition of Greenfield’s Surgery: Scientific Principles and Practice remains the gold standard text in the field of surgery. It reflects surgery’s rapid changes, new technologies, and innovative techniques, integrating new scientific knowledge with evolving changes in surgical care. Updates to this edition include new editors and contributors, and a greatly enhanced visual presentation. Balancing scientific advances with clinical practice, Greenfield’s Surgery is an invaluable resource for today’s residents and practicing surgeons.

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5781

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

146989002X

ISBN 13

9781469890029

Mathematical Models in the Biosciences II

By: Michael Frame

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Mathematical Models in the Biosciences II

By: Michael Frame

Volume Two of an award-winning professor’s introduction to essential concepts of calculus and mathematical modeling for students in the biosciences This is the second of a two-part series exploring essential concepts of calculus in the context of biological systems. Building on the essential ideas and theories of basic calculus taught in Mathematical Models in the Biosciences I, this book focuses on epidemiological models, mathematical foundations of virus and antiviral dynamics, ion channel models and cardiac arrhythmias, vector calculus and applications, and evolutionary models of disease. It also develops differential equations and stochastic models of many biomedical processes, as well as virus dynamics, the Clancy-Rudy model to determine the genetic basis of cardiac arrhythmias, and a sketch of some systems biology. Based on the author’s calculus class at Yale, the book makes concepts of calculus less abstract and more relatable for science majors and premedical students.

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493

Publisher

Yale University Press

Published Date

ISBN 10

0300263791

ISBN 13

9780300263794

Kumar & Clark's Cases in Clinical Medicine

By: Parveen Kumar,Michael L Clark, MD, FRCP

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Kumar & Clark's Cases in Clinical Medicine

By: Parveen Kumar,Michael L Clark, MD, FRCP

2014 BMA Medical Book Awards 1st Prize Award Winner in Medicine category! More than 200 cases Remember! boxes Investigations boxes Information boxes More than 200 cases

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609

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0702031380

ISBN 13

9780702031380

Atlas of Liver Pathology: A Pattern-Based Approach

By: Michael Torbenson

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Atlas of Liver Pathology: A Pattern-Based Approach

By: Michael Torbenson

Part of the new Pattern-Based Approach series, designed to teach pathology in a way that reflects actual sign-out, this new visually-oriented guidebook presents real-life cases and practical diagnostic tips. Disease processes are organized into ‘patterns’ of injury—the method by which pathologists approach their work—and self-assessment quizzes are provided for each chapter to give you experience with high-yield, board-style teaching topics.

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1134

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1496396995

ISBN 13

9781496396990

Kumar & Clark's Cases in Clinical Medicine E-Book

By: Parveen Kumar,Michael L Clark

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Kumar & Clark's Cases in Clinical Medicine E-Book

By: Parveen Kumar,Michael L Clark

The latest addition to the Kumar & Clark family, this thoroughly updated new edition covers more than 200 cases presenting with acute symptoms in the hospital, everything from shingles and breathlessness to chest pain, acute coronary syndromes, poisoning, renal failure and stroke. The authors give clear and concise advice on immediate and further management, management of complications, differential diagnoses, history-taking, tips and pitfalls, alerts, investigations, and prioritization. • More than 200 cases• Remember! boxes• Investigations boxes• Information boxes Edited by Parveen Kumar, CBE, BSc, MD, FRCP, FRCP(Edin) and Michael L Clark, MD, FRCP Enhanced e-book accompanies the print book, for ease of transportation and use on the move. Over 200 cases

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585

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Elsevier Health Sciences

Published Date

ISBN 10

070207733X

ISBN 13

9780702077333

New and Exploratory Therapeutic Agents for Asthma

By: Michael Yeadon,Zuzana Diamant

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New and Exploratory Therapeutic Agents for Asthma

By: Michael Yeadon,Zuzana Diamant

Discusses three major classes of asthma therapies-bronchodilators, antiinflammatories, and antiallergics-as well as potential new therapeutic approaches! This comprehensive volume addresses the latest treatment strategies for asthma, keying in on the genetics and molecular biology of asthma and pointing the way toward new, commercially viable therapies. Presents the most up-to-date information available on the genetics, epidemiology, pathology, pharmacology, and pulmonology of asthma. Written by more than 20 leading international experts, New and Exploratory Therapeutic Agents for Asthma explores asthma both as incidence of dysfunctional airway smooth muscle and as a disorder of the immune system examines the role of monoclonal antibodies in allergy and asthma describes functions and pharmacokinetic profiles of bronchodilator 2 agonists, anticholinergics, and inhaled glucocorticosteroids investigates the controversy of different types of asthma illustrates the connections between clinical symptoms and the immunopathology of eosinophilic inflammation assesses prospects for the development of a successful oral anti-inflammatory therapy, an immunomodulator that lowers antigen-specific IgE, an anticytokine compound, and an agent that safely combines bronchospasmolytic and anti-inflammatory properties reviews the impact of the recent introduction of antileukotriene agents, clinical findings with PAF antagonists, and selective antimuscarinics evaluates the relationship between improvements in laboratory results and clinical effectiveness and more! Containing over 2000 bibliographic citations and a concise introduction for each chapter, New and Exploratory Therapeutic Agents for Asthma is indispensable for pulmonologists, pediatricians, physiologists, immunologists, allergists, pharmaceutical industry scientists, primary care physicians, and medical school students in these disciplines.

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549

Publisher

CRC Press

Published Date

ISBN 10

0824746813

ISBN 13

9780824746810

Neuromuscular Diseases

A Practical Approach to Diagnosis and Management

By: Michael Swash,Martin S. Schwartz

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Neuromuscular Diseases

A Practical Approach to Diagnosis and Management

By: Michael Swash,Martin S. Schwartz

In the seven years since the first edition of this book was published there have been many important developments in knowledge of neuromuscular diseases. These are reflected in this new edition. We have taken the opportunity to add much new clinical and scientific material to the book, particularly in relation to metabolic myopathies and neuropathies, and to include more information on genetic aspects of neuromuscular diseases, quantitative electromyo graphic techniques, plexus and root lesions and cardiomyopathies. The aim of the book remains unchanged, but we have rearranged some of the material so that there are several new chapters. The illustrations have also been extensively revised and there are many new references. We hope that it will continue to provide a convenient source of practical and theoretical information that will not only be useful in managing patients with neuromuscular diseases, but will stimulate research. London, May 1987 Michael Swash Martin S. Schwartz Preface to the First Edition Neuromuscular diseases are common in clinical practice. Patients with these disorders may be referred to neurologists, rheumatologists, orthopaedic surgeons, paediatricians or to general physicians, and their investigation, utilising electromyography (EM G) and muscle biopsy, often requires the help of the clinical neurophysiologist and of the pathologist.

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467

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1447135261

ISBN 13

9781447135265

Heat Shock Proteins and Whole Body Adaptation to Extreme Environments

By: Michael B. Evgen'ev,David G. Garbuz,Olga G. Zatsepina

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Heat Shock Proteins and Whole Body Adaptation to Extreme Environments

By: Michael B. Evgen'ev,David G. Garbuz,Olga G. Zatsepina

For many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. We also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, we describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.

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233

Publisher

Springer

Published Date

ISBN 10

9401792356

ISBN 13

9789401792356

Atlas and Synopsis of Lever's Histopathology of the Skin

By: David E. Elder,Rosalie Elenitsas,Adam I. Rubin,Michael Ioffreda,Jeffrey Miller,O. Fred Miller

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Atlas and Synopsis of Lever's Histopathology of the Skin

By: David E. Elder,Rosalie Elenitsas,Adam I. Rubin,Michael Ioffreda,Jeffrey Miller,O. Fred Miller

Atlas and Synopsis of Lever's Histopathology of the Skin provides a systematic approach to diagnosing skin diseases. Written for trainees as well as experienced dermatopathologists, this text classifies skin diseases by location, reaction patterns, and cell type, if applicable. Revised and updated based on the 10th edition of Lever's Histopathology of the Skin, it greatly expands the concept of pattern recognition in differential diagnosis.

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561

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1451171633

ISBN 13

9781451171631

Forensic Pathology of Fractures and Mechanisms of Injury

Postmortem CT Scanning

By: Michael P. Burke

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Forensic Pathology of Fractures and Mechanisms of Injury

Postmortem CT Scanning

By: Michael P. Burke

Practitioners of forensic medicine have various tools at their disposal to determine cause of death, and today‘s computed tomography (CT) can provide valuable clues if images are interpreted properly. This volume is a guide for the forensic pathologist who wants to use CT imaging to assist in determining the mechanism of injury that might have contributed to death. Enhanced with hundreds of CT images that clarify the text and case studies to put the material in context, the book gives a head-to-toe catalogue of various injuries and how they are represented on a CT scan.

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Page Count

270

Publisher

CRC Press

Published Date

ISBN 10

1439881499

ISBN 13

9781439881491

Basic Exercise Physiology

Clinical and Laboratory Perspectives

By: Moran S. Saghiv,Michael S. Sagiv

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Basic Exercise Physiology

Clinical and Laboratory Perspectives

By: Moran S. Saghiv,Michael S. Sagiv

This book reviews the assessment of human performance and the role of different exercise modes both in a laboratory and clinical setting. Details of how to successfully perform basic laboratory procedures for exercise training in health and disease, as well as how to apply non-invasive measurements in exercise physiology are provided. Chapters cover how to appropriately use a range of measures in assessing pulmonary function, anaerobic function and oxygen uptake. Techniques for cardiopulmonary rehabilitation and the mechanisms associated with thermoregulation are also described. Interactive exercises enable readers to easily assimilate key concepts and develop a thorough understanding of the topic. Basic Exercise Physiology provides both trainees and professional healthcare staff interested in exercise physiology with a detailed and practically applicable resource on the topic.

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582

Publisher

Springer Nature

Published Date

ISBN 10

3030488063

ISBN 13

9783030488062

Kumar and Clark's Clinical Medicine E-Book

By: Parveen Kumar,Michael L Clark

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Kumar and Clark's Clinical Medicine E-Book

By: Parveen Kumar,Michael L Clark

Kumar & Clark’s Clinical Medicine 8 builds on the prize-winning formula that won the first prize in the BMA Book Awards Medicine Category in 2010 (7th edition) and 2006 (6th edition). ‘This book is comprehensive, student friendly (if still intimidating in size!) and covers such a vast breadth of knowledge. It still remains the primary ‘must-have’ text book of any budding doctor, or qualified one at that. This book is stunning in its breadth and in its ease of use. It still remains as the ‘gold-standard’ thorough guide to clinical medicine its forefathers were.’ BMA Judges 2010 'This is one of a select few books that deserves to be in most doctors' personal possession and it's as simple as that. ...’ Dr Harry Brown. New to this edition: New chapter on palliative medicine. Five times the number of margin clinical photos. New echocardiography images. Double the number of dermatological images; including all the major lesion morphologies covered in a single page. 16 new authors. New sections on protein synthesis, energy production and stem cells. New members of the International Advisory Board from India, South Africa, Poland and the Middle East. 7 new online chapters from the International Advisory Board. Key online features: 30 extra short chapters online, written by members of the International Advisory Board to cover key international issues, such as malaria, envenoming and HIV. Animated practical procedures, including lumbar puncture, central venous and bladder catheterization, arterial cannulation etc. heart and lung sounds, and interactive surface anatomy available online. Full text online through StudentConsult. Add your own notes and bookmarks. Search across all the StudentConsult resources you own online in one place. New to this edition: New chapter on palliative medicine. Five times the number of margin clinical photos. New echocardiography images. Double the number of dermatological images; including all the major lesion morphologies covered in a single page. 16 new authors. New sections on protein synthesis, energy production and stem cells. New members of the International Advisory Board from India, South Africa, Poland and the Middle East. 7 new online chapters from the International Advisory Board.

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1303

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Elsevier Health Sciences

Published Date

ISBN 10

070205304X

ISBN 13

9780702053047

Rheumatoid Arthritis E-Book

By: Marc C. Hochberg,Alan J. Silman,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman

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Rheumatoid Arthritis E-Book

By: Marc C. Hochberg,Alan J. Silman,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman

First Prize, Orthopaedics and Rheumatology, BMA Awards 2009 This state-of-the-art reference provides current insights into the etiology, diagnosis and management of rheumatoid arthritis. Leading international authorities in RA examine all of the latest scientific and clinical developments in understanding and managing this challenging disease, including new concepts in pathogenesis, epidemiology, risk factors, imaging, clinical outcomes and treatment. It’s the guidance you need to offer optimal care to your patients with rheumatoid arthritis. Presents the work of leading international experts in rheumatoid arthritis for guidance you can trust. Provides the very latest understanding of the pathogenesis of rheumatoid arthritis, including molecular pathways/mechanisms, and genetic and environmental factors that instigate and drive the disease. Includes comprehensive coverage of clinical features of rheumatoid arthritis including articular, peri-articular and extra-articular manifestations, comorbidities, and outcome measures—disease activity, joint assessment, imaging, and more—for expert diagnosis and monitoring of disease progression. Examines evidence-based treatment options—including traditional and biologic DMARDs and combination therapies—as well as promising therapies on the horizon, placing up-to-date guidance on disease modifying or disease controlling agents at your fingertips.

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462

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Elsevier Health Sciences

Published Date

ISBN 10

0323071023

ISBN 13

9780323071024

Perry's The Chemotherapy Source Book

By: Michael C. Perry,Donald C. Doll,Carl E. Freter

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Perry's The Chemotherapy Source Book

By: Michael C. Perry,Donald C. Doll,Carl E. Freter

Perry’s The Chemotherapy Source Book, now in its fifth edition, provides information on the choice of chemotherapeutic agents, the use of combination chemotherapy, and the toxicity of individual drugs. Organized by site, this is the only book of its kind to focus strictly on the clinical practice of chemotherapy, and is meant to serve as a “one-stop shop” for information on choice of chemotherapeutic agents, treatment outlines, grading of side effects, and dose modification.

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850

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1469803437

ISBN 13

9781469803432

Levin and O'Neal's the Diabetic Foot

By: Marvin E. Levin,John H. Bowker,Michael A. Pfeifer

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Levin and O'Neal's the Diabetic Foot

By: Marvin E. Levin,John H. Bowker,Michael A. Pfeifer

Fully updated, now in full color, this latest edition of Levin and O'Neal's The Diabetic Foot provides diagnostic and management information for the challenging problems faced by patients with diabetic foot problems. The book has a team care focus and offers tips and pearls in every chapter.

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648

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Elsevier Health Sciences

Published Date

ISBN 10

0323041450

ISBN 13

9780323041454

The Shoulder E-Book

By: Charles A. Rockwood,Michael A. Wirth

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The Shoulder E-Book

By: Charles A. Rockwood,Michael A. Wirth

Significantly revised and updated, the new edition of this highly regarded reference on the shoulder continues to impress. A multitude of leading international authorities—30% new to this 4th edition—present today’s most comprehensive, in-depth view of the current state of shoulder practice, all in a beautifully illustrated, full-color 2-volume masterwork. They deliver the most up-to-date coverage of shoulder function and dysfunction, along with practical approaches for patient evaluation and balanced discussions of treatment alternatives—open and arthroscopic, surgical and nonsurgical. Greatly expanded and visually enhanced coverage of arthroscopy, as well as many new chapters, provide expert guidance on the latest minimally invasive approaches. New “Critical Points summary boxes highlight key technical tips and pearls, and two DVDs deliver new videos that demonstrate how to perform open and arthroscopic procedures. And now, as an Expert Consult title, this thoroughly updated 4th edition comes with access to the complete fully searchable contents online, as well as videos of arthroscopic procedures from the DVDs—enabling you to consult it rapidly from any computer with an Internet connection. Includes tips and pearls from leaders in the field, as well as their proven and preferred methods. Offers scientifically based coverage of shoulder function and dysfunction to aid in the decision-making process. Provides a balance between open and arthroscopic techniques so you can chose the right procedures for each patient. Includes the entire contents of the book online, fully searchable, as well as procedural videos from the DVDs, for quick, easy anywhere access. Features 30% new expert contributors and new chapters, including Effectiveness Evaluation and the Shoulder, Revision of Rotator Cuff Problems, Management of Complications of Rotator Cuff Surgery, Management of Infected Shoulder Prosthesis, and others, providing you with abundant fresh insights and new approaches. Provides new and expanded material on the management of advanced arthritis and CTA, infected arthroplasty, procedures to manage the stiff shoulder, and much more keeping you on the cusp of the newest techniques. Offers enhanced coverage of shoulder arthroscopy, including basic and advanced techniques and complications, for expert advice on all of the latest minimally invasive approaches. Devotes an entire new chapter to research frontiers to keep you apprised of what’s on the horizon. Incorporates “Critical Points summary boxes that highlight key technical tips and pearls. Uses a new full-color design for optimal visual guidance of arthroscopic views and procedures. Presents new videos on arthroscopic procedures on 2 DVDs to help you master the latest techniques.

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1631

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

143772082X

ISBN 13

9781437720822

Murray & Nadel's Textbook of Respiratory Medicine E-Book

By: Robert J. Mason,Arthur Slutsky,John F. Murray,Jay A. Nadel,Michael B. Gotway

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Murray & Nadel's Textbook of Respiratory Medicine E-Book

By: Robert J. Mason,Arthur Slutsky,John F. Murray,Jay A. Nadel,Michael B. Gotway

Ideal for fellows and practicing pulmonologists who need an authoritative, comprehensive reference on all aspects of pulmonary medicine, Murray and Nadel’s Textbook of Respiratory Medicine offers the most definitive content on basic science, diagnosis, evaluation and treatment of the full spectrum of respiratory diseases. Full-color design enhances teaching points and highlights challenging concepts. Understand clinical applications and the scientific principles of respiratory medicine. Detailed explanations of each disease entity allow you to work through differential diagnoses. Expert Consult eBook version included with purchase. This enhanced eBook experience offers content updates, videos, review questions, and Thoracic Imaging Cases (TICs), all of which are easily navigable on any device for access on rounds or in the clinic. Includes more than 1,000 figures and over 200 videos and audio files. Key Points and Key Reading sections highlight the most useful references and resources for each chapter. An expanded sleep section now covers four chapters and includes control of breathing, consequences of sleep disruption, as well as obstructive and central apnea. New chapters in the Critical Care section cover Noninvasive Ventilation (NIV) and Extracorporeal Support of Gas Exchange (ECMO). New chapters focusing on diagnostic techniques now include Invasive Diagnostic Imaging and Image-Guided Interventions and Positron Emission Tomography, and a new chapter on Therapeutic Bronchoscopy highlights the interventional role of pulmonologists. Embedded videos feature thoracoscopy, therapeutic bronchoscopy, volumetric chest CT scans, and more. Brand-new audio files highlight normal and abnormal breath sounds and the separate components of cough.

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3047

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Elsevier Health Sciences

Published Date

ISBN 10

0323261930

ISBN 13

9780323261937

Abeloff's Clinical Oncology E-Book

By: John E. Niederhuber,James O. Armitage,James H Doroshow,Michael B. Kastan,Joel E. Tepper

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Abeloff's Clinical Oncology E-Book

By: John E. Niederhuber,James O. Armitage,James H Doroshow,Michael B. Kastan,Joel E. Tepper

Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.

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2712

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Elsevier Health Sciences

Published Date

ISBN 10

1455728810

ISBN 13

9781455728817

Homeostatic and Retrograde Signaling Mechanisms Modulating Presynaptic Function and Plasticity

By: Michael A. Sutton,Dion Dickman

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Homeostatic and Retrograde Signaling Mechanisms Modulating Presynaptic Function and Plasticity

By: Michael A. Sutton,Dion Dickman

Activity within neural circuits shapes the synaptic properties of component neurons in a manner that maintains stable excitatory drive, a process referred to as homeostatic plasticity. These potent and adaptive mechanisms have been demonstrated to modulate activity at the level of an individual neuron, synapse, circuit, or entire network, and dysregulation at some or all of these levels may contribute to neuropsychiatric disorders, intellectual disability, and epilepsy. Greater mechanistic understanding of homeostatic plasticity will provide key insights into the etiology of these disorders, which may result from network instability and synaptic dysfunction. Over the past 15 years, the molecular mechanisms of this form of plasticity have been intensely studied in various model organisms, including invertebrates and vertebrates. Though once thought to have a predominantly postsynaptic basis, emerging evidence suggests that homeostatic mechanisms act on both sides of the synapse through mechanisms such as retrograde signaling, to orchestrate compensatory adaptations that maintain stable network function. These trans-synaptic signaling systems ultimately alter neurotransmitter release probability by a variety of mechanisms including changes in vesicle pool size and calcium influx. These adaptations are not expected to occur homogenously at all terminals of a pre-synaptic neuron, as they might synapse with neurons in non-overlapping circuits. However, the factors that govern the homeostatic control of synapse-specific plasticity are only beginning to be understood. In addition to our limited molecular understanding of pre-synaptic homeostatic plasticity, very little is known about its prevalence in vivo or its physiological and disease relevance. In this research topic, we aim to fill the aforementioned void by covering a broad range of topics that include: - Identification of signaling pathways and mechanisms that operate globally or locally to induce specific pre-synaptic adaptations - The nature of pre-synaptic ion channels relevant to this form of plasticity and their synapse-specific modulation and trafficking - Development and utilization of new tools or methods to study homeostatic plasticity in axons and pre-synaptic terminals - Novel mechanisms of homeostatic adaptations in pre-synaptic neurons - Postsynaptic sensors of activity and retrograde synaptic signaling systems - A comprehensive analysis of the kinds of pre-synaptic adaptations in diverse neural circuits and cell types - Identification of physiological or developmental conditions that promote pre-synaptic homeostatic adaptations - How activity-dependent (Hebbian) and homeostatic synaptic changes are integrated to both permit sufficient flexibility and maintain stable activity - Relevance of pre-synaptic homeostatic plasticity to the etiology of neuropsychiatric disorders - Computational modeling of pre-synaptic homeostatic plasticity and network stability.

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Page Count

154

Publisher

Frontiers Media SA

Published Date

ISBN 10

2889197042

ISBN 13

9782889197040

Book's by Michael Tsokos

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