Cholestatic liver diseases, such as primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC), represent an important group of liver diseases of the intra- and extrahepatic bile ducts frequently causing end-stage liver disease with significant morbidity and mortality due to limited treatment options. The limitations of the currently available medical therapy largely reflect our deficits in understanding the pathophysiology of cholestatic liver diseases. Therefore, there is an urgent need for reliable, well-defined and easily reproducible animal models to gain insights into the PSC and PBC pathophysiology and to test novel treatment modalities. We aimed to provide a systematic overview of currently available animal models for sclerosing cholangitis and biliary fibrosis and critically discuss the characteristics of rodent models for PSC and PBC, models of experimental biliary obstruction, models of inflammation-induced cholestasis, as well as models of inherited cholestatic syndromes.
A reactions oriented course is a staple of most graduate organic programs, and synthesis is taught either as a part of that course or as a special topic. Ideally, the incoming student is an organic major, who has a good working knowledge of basic reactions, stereochemistry and conformational principles. In fact, however, many (often most) of the students in a first year graduate level organic course have deficiencies in their undergraduate work, are not organic majors and are not synthetically inclined. To save students much time catching up this text provides a reliable and readily available source for background material that will enable all graduate students to reach the same high level of proficiency in organic chemistry. Produced over many years with extensive feedback from students taking an organic chemistry course this book provides a reaction based approach. The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to 'disconnect' a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader's understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists. The book is intended for graduate and postgraduate students, scientific researchers in chemistry - New publisher, new edition; extensively updated and corrected - Over 950 new references with more than 6100 references in total - Over 600 new reactions and figures replaced or updated - Over 300 new homework problems from the current literature to provide nearly 800 problems to test reader understanding of the key principles
Zakim and Boyer's Hepatology-the defining work in hepatology-presents comprehensive coverage of both basic science and clinically relevant developments so you can provide the best possible patient care. Drs. Thomas Boyer, Michael Manns, and Arun Sanyal have reorganized and updated the contents of this trusted global reference to reflect today's more clinical approach to hepatology. They bring you up to date on hot topics including HIV Co-Infection Drug Toxicity, Hepatocellular Carcinoma (HCC), and much more. This new streamlined edition is now a single volume with access to the fully searchable contents and an image bank online at www.expertconsult.com making it easier to find the treatment information you need. Effectively treat all liver diseases currently seen in clinical practice with authoritative guidance from leading international authorities. Reinforce your foundation in basic science with the concise Pathophysiology of Therapeutic Targets section. See clear presentations of liver disease through hundreds of detailed, color illustrations. Explore topics further with up-to-date references that direct you to the significant literature. Access the complete, fully searchable contents of the book online at www.expertconsult.com, along with a downloadable image bank and complete list of references. Stay current on new developments in the field through five new chapters on Pathogenesis Liver Injury in HBV, HCV; HCC; Imaging and Non-Invasive DX Liver Disease CT, US, Fibroscan, MRI; HIV Co-Infection Drug Toxicity; and HBC, HCV in Non-Liver Transplant Patients, plus comprehensive updates throughout. Apply best practices with reorganized and updated content that reflects today's need for a more clinical approach to hepatology. Reference key information more easily thanks to streamlined content that now fits into one volume.
The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.
A comprehensive introduction to the role of epidemiology in veterinary medicine This fully revised and expanded edition of Veterinary Epidemiology introduces readers to the field of veterinary epidemiology. The new edition also adds new chapters on the design of observational studies, validity in epidemiological studies, systematic reviews, and statistical modelling, to deliver more advanced material. This updated edition begins by offering an historical perspective on the development of veterinary medicine. It then addresses the full scope of epidemiology, with chapters covering causality, disease occurrence, determinants, disease patterns, disease ecology, and much more. Veterinary Epidemiology, Fourth Edition: ● Features updates of all chapters to provide a current resource on the subject of veterinary epidemiology ● Presents new chapters essential to the continued advancement of the field ● Includes examples from companion animal, livestock, and avian medicine, as well as aquatic animal diseases ● Focuses on the principles and concepts of epidemiology, surveillance, and diagnostic-test validation and performance ● Includes access to a companion website providing multiple choice questions Veterinary Epidemiology is an invaluable reference for veterinary general practitioners, government veterinarians, agricultural economists, and members of other disciplines interested in animal disease. It is also essential reading for epidemiology students at both the undergraduate and postgraduate levels.
AQA Psychology for AS and A-level Year 1 is the definitive textbook for the new 2015 curriculum. Written by eminent psychologist Professor Michael Eysenck, in collaboration with a team of experienced A-level teachers and examiner, the book enables students not only to pass their exams with flying colours, but also to fully engage with the science of psychology. As well as covering the six core topics students will study, the book includes: Activities which test concepts or hypotheses, bringing theory to life Key research studies explained and explored, showing the basis on which theory has developed Case studies which show how people’s lives are affected by psychological phenomena Evaluation boxes which critically appraise key concepts and theories Self-assessment questions which encourage students to reflect on what they’ve learnt Section summaries to support the understanding of specific ideas – perfect for revision Exam hints which steer students towards complete and balanced answers Key terms defined throughout so students aren’t confused by new language 200 figures, tables and photos End of chapter further reading to enable students to develop a deeper understanding End of chapter revision questions and sample exam papers to consolidate knowledge and practice exam technique A full companion website with a range of further resources for both students and teachers, including revision aids and class materials Incorporating greater coverage of research methods, as well as key statistical techniques, the sixth edition of this well-loved textbook continues to be the perfect introduction to psychology. Accessible yet rigorous, the book is the ideal textbook for students taking either the AS course or year 1 of the A-level.
Chromic or colour related phenomena are produced in response to a chemical or physical stimulus. This new edition will update the information on all those areas where chemicals or materials interact with light to produce colour, a colour change, or luminescence especially in the imaging, analysis, lighting and display areas. The book has been restructured to show greater emphasis on applications where 'coloured' compounds are used to transfer energy or manipulate light in some way therefore reducing the details on classical dyes and pigments. In the past eight years, since the previous edition, there has been a remarkable increase in the number of papers and reviews being produced reflecting the growth of interest in this area. This ongoing research interest is matched by a large number of new technological applications gaining commercial value covering e.g. biomedical areas, energy, data storage, physical colour, bio-inspired materials and photonics. This book appeals to industrial chemists, professionals, postgraduates and as high level recommended reading for colour technology courses.
The application of digital information and communication technologies (ICTs) to reform governmental structures, politics, and public administration is widely and perhaps naively viewed as the twenty-first century "savior," the enlightened way to reinvigorate democracy and improve the quality of citizen services. In this timely and thorough analysis, Michael Milakovich examines the assumptions underlying the ‘e-government revolution’ in light of the financial exigencies facing many commercial enterprises, governments and other organizations. Computer-driven information and communications technologies are impacting all aspects of public sector service delivery worldwide and many governments are moving away from an agency-centric toward a more citizen-centric approach to offering online services. This book explores the transition from electronic government (e-gov) to digital or d-governance, emphasizing the importance of citizen participation and information technology to accomplish the change. The chapters concentrate on strategies for public administration organizational transformation and their implications for improved and measurable government performance. Digital self-governance is a broader umbrella-term referring to the networked extension of ICT relationships to include faster access to the web, mobile service delivery, networking, teleconferencing and use of multi-channel information technologies to accomplish higher-level two-way transactions. The shift from bureaucracy-centered to customer-centric service orientation is viewed as a means to restore public trust and improve service quality: Digital governance is the next step for governments at all levels to reduce costs, meet citizen expectations, and achieve economic recovery goals.
Symbolic regression (SR) is one of the most powerful machine learning techniques that produces transparent models, searching the space of mathematical expressions for a model that represents the relationship between the predictors and the dependent variable without the need of taking assumptions about the model structure. Currently, the most prevalent learning algorithms for SR are based on genetic programming (GP), an evolutionary algorithm inspired from the well-known principles of natural selection. This book is an in-depth guide to GP for SR, discussing its advanced techniques, as well as examples of applications in science and engineering. The basic idea of GP is to evolve a population of solution candidates in an iterative, generational manner, by repeated application of selection, crossover, mutation, and replacement, thus allowing the model structure, coefficients, and input variables to be searched simultaneously. Given that explainability and interpretability are key elements for integrating humans into the loop of learning in AI, increasing the capacity for data scientists to understand internal algorithmic processes and their resultant models has beneficial implications for the learning process as a whole. This book represents a practical guide for industry professionals and students across a range of disciplines, particularly data science, engineering, and applied mathematics. Focused on state-of-the-art SR methods and providing ready-to-use recipes, this book is especially appealing to those working with empirical or semi-analytical models in science and engineering.
For 25 years, Lewis's Child and Adolescent Psychiatry has been the cornerstone of every child and adolescent psychiatrist’s library. Now, three colleagues of Dr. Lewis at the world-renowned Yale Child Study Center, have substantially updated and revised this foundational textbook for its long-awaited fifth edition, the first in ten years. Encyclopedic in scope, it continues to serve as a broad reference, deftly encompassing and integrating scientific principles, research methodologies, and everyday clinical care.
In the World Library of Psychologists series, international experts present career-long collections of what they judge to be their finest pieces - extracts from books, key articles, salient research findings, and their major practical theoretical contributions. This influential volume of papers, chosen by Professor Annette Karmiloff-Smith before she passed away, recognises her major contribution to the field of developmental psychology. Published over a 40-year period, the papers included here address the major themes that permeate through Annette’s work: from typical to atypical development, genetics and computation modelling approaches, and neuroimaging of the developing brain. A newly written introduction by Michael S. C. Thomas and Mark H. Johnson gives an overview of her research journey and contextualises her selection of papers in relation to changes in the field over time. Thinking Developmentally from Constructivism to Neuroconstructivism: Selected Works of Annette Karmiloff-Smith is of great interest to researchers and postgraduates in child development specialising in atypical development, developmental disorders, and developmental neuroscience. It also has appeal to clinical neuropsychologists and rehabilitation professionals.
Neurodevelopmental disabilities are a common problem in child health. This book takes a comprehensive approach to addressing these often challenging clinical diagnoses. In particular, it focuses on the two most common of childhood neurodevelopmental disabilities: global developmental delay and developmental language impairment. It seeks to put forward our present conceptualization of these entities as well as their proper evaluation and assessment and diagnosis from a variety of perspectives. It also provides details on our current understanding of the scientific basis of these disorders and their underlying causes. Issues related to medical management, rehabilitation, and eventual outcomes are also addressed in a detailed way. The book has wide appeal to those in paediatrics, developmental paediatrics, child neurology, and paediatric rehabilitation. Its geographic appeal includes both developed and developing nations as some chapters are devoted to the particular issues faced in underdeveloped countries. The book’s focus on both clinical and scientific aspects is invaluable in this field. It also provides extensive information in a single source relating to often-overlooked areas such as medical management, rehabilitation, public policy, and ethics.
This book explores the relationship between vision and learning and the role of optometrists in the assessment and management of learning related vision problems. It discusses normal child development, the learning process, learning disabilities, the relationship between vision and learning, and models for managing vision problems affecting learning. It is also of interest to health care practitioners involved in the evaluation and treatment of children and adults with learning difficulties. Instructor resources are available; please contact your Elsevier sales representative for details. Presents an organized, easy-to-follow approach to the diagnosis and treatment of learning-related vision problems.Each chapter contains key terms and chapter review questions making it more appealing to the student and instructor.Includes appendices containing sample reports, sample questionnaires, sample letters, a bibliography, and case histories showing the reader how to use the material from the book in practice.Well respected authors and contributors provide authoritative coverage of the topic. Expanded information on the use of colored lenses and reading.New chapter on reading disorders that covers how children learn to read, teaching methods, optometric assessment, and management of dyslexia.Chapters have been updated with new computer software options, including computer aided vision therapy, perceptual home therapy system, and temporal visual processing program.Updated testing battery, including new tests, visual processing speed, and optometric use of IQ screening tests such as K-BIT.Expanded coverage of psycho education evaluation includes substantial updates with new test instruments, such as WISC.Substantial revisions based on literature review for last 10 years.New and updated illustrations.
A wide-ranging study of Prévert’s promethean imagination and creativity in the interwoven realms of theatre, film, poetry, art, photography, and song, Michael Bishop’s Jacques Prévert seeks to demonstrate the originality of a genial fabricator of image and word whose essential focus, unpretentious yet urgently felt, unintellectualised yet buoyantly and wittily intelligent, ever remains the quality of our daily being-in-the-world, the possibility of our self-transformation, the stunning availability – should we truly will it, and despite all that can weigh upon existence, above all ideologically – of joy and love and freedom.
Despite the fact that many countries target highly skilled migrants for recruitment in the global labour market, few of those migrants are able to take full advantage of their educational and professional qualifications in their new homes. Work in Transition examines this paradox, using extended narrative interviews that focus on the role that cultural capital plays in the labour market. Comparing the migrant experience in Germany, Canada, and Turkey, Work in Transition shows how migrants develop their cultural capital in order to enter the workforce, as well as how failure to leverage that capital can lead to permanent exclusion from professional positions. Exposing the mechanisms that drive inclusion and exclusion for migrants from a transatlantic comparative perspective, this book provides a unique analytical approach to an increasingly important global issue.
Heteroepitaxial films are commonplace among today's electronic and photonic devices. The realization of new and better devices relies on the refinement of epitaxial techniques and improved understanding of the physics underlying epitaxial growth. This book provides an up-to-date report on a wide range of materials systems. The first half reviews metallic and dielectric thin films, including chapters on metals, rare earths, metal-oxide layers, fluorides, and high-c superconductors. The second half covers semiconductor systems, reviewing developments in group-IV, arsenide, phosphide, antimonide, nitride, II-VI and IV-VI heteroepitaxy. Topics important to several systems are covered in chapters on atomic processes, ordering and growth dynamics.
Often forgotten among the actors, directors, producers and others associated with filmmaking, art directors are responsible for making movies visually appealing to audiences. As such they sometimes make the difference between a hit and a bomb. This biographical dictionary includes not only the world's great and almost-great artists, but the unjustly neglected film designers of the past and present. Among the more than 300 art directors and designers are pioneers from silent films, designers from Hollywood and Europe's Golden Ages, Asian figures, post-Golden Age personalities, leaders of the European and American New Waves, and many contemporary designers. Each entry consists of biographical information, an analysis of the director's career and important films, and an extensive filmography including mentions of Academy Award nominations and winners.
Michael Burleigh's The Third Reich presents a major study of one of the twentieth century's darkest periods. Until now there has been no up-to-date, one-volume, international history of Nazi Germany, despite its being among the most studied phenomena of our time. The Third Reich restores a broad perspective and intellectual unity to issues that have become academic subspecialties and offers a brilliant new interpretation of Hitler's evil rule. Filled with human and moral considerations that are missing from theoretical accounts, Michael Burleigh's book gives full weight to the experience of ordinary people who were swept up in, or repelled by, Hitler's movement and emphasizes how international themes for Nazi Germany appealed to many European nations. It also focuses on the Nazi's wartime conduct to dominate the Continental economy and involve gigantic population transfers and exterminations, recruitment of foreign labor, and multinational armies.
Within American service sector organizations there exists a gap between understanding customer service quality improvement (QI) theories and applying them. Improving Service Quality in the Global Economy: Achieving High Performance in Public and Private Sectors, Second Edition fills that gap by presenting theory, application models, and cases of su
Playing Sherlock Holmes contains three verbatim interviews - with John Wood, Robert Stephens and Christopher Lee - about their very different experiences of appearing as Holmes on stage and screen. The interviews were conducted in 1974. At the time, John Wood was appearing on stage in an acclaimed revival of William Gillette's play Sherlock Holmes, a Royal Shakespeare Company production; Robert Stephens had recently completed The Private Life of Sherlock Holmes for film director Billy Wilder; and Christopher Lee - who had a role as Mycroft Holmes in that film - had earlier played the lead role in Sherlock Holmes and the Deadly Necklace. The interviews have been transcribed from tapes held in the Arthur Conan Doyle Collection - Richard Lancelyn Green Bequest at Portsmouth Museum.
The distinguished psychologist Michael Cole, known for his pioneering work in literacy, cognition, and human development, offers a multifaceted account of what cultural psychology is, what it has been, and what it can be. A rare synthesis of the theory and empirical work shaping the field, this book will become a major foundation for the emerging discipline.
This book bridges the gap between sophomore and advanced / graduate level organic chemistry courses, providing students with a necessary background to begin research in either an industry or academic environment. • Covers key concepts that include retrosynthesis, conformational analysis, and functional group transformations as well as presents the latest developments in organometallic chemistry and C–C bond formation • Uses a concise and easy-to-read style, with many illustrated examples • Updates material, examples, and references from the first edition • Adds coverage of organocatalysts and organometallic reagents
Explore the many changes in hip and knee arthroplasty in recent years with completely new chapters on thromboprophylaxis, outpatient surgery, pain management, retrieval—hip and knee, medical and biologic treatment of arthritis, nonarthroplasty management, infection, periprosthetic fracture, anatomy and surgical approaches, and dual-mobility cups and large-diameter heads for primary and revision total hip arthroplasty. Expand your knowledge with the standard in adult hip and knee reconstruction, while you advance patient care with the best practices available. Developed in partnership with The Hip Society and The Knee Society, OKU® Hip and Knee Reconstruction 6 examines current research and reviews of the most relevant topics chosen by recognized authorities. Find a wealth of information on cutting-edge developments and approaches for surgically challenging conditions. Orthopaedic surgeons with a specialty interest in hip and knee reconstruction, and physicians and allied health interested in staying up to date on best practices will benefit from this edition. Residents in training can review key topics paired with helpful guidelines and images.
The only combined organic photochemistry and photobiology handbookAs spectroscopic, synthetic and biological tools become more and more sophisticated, photochemistry and photobiology are merging-making interdisciplinary research essential. Following in the footsteps of its bestselling predecessors, the CRC Handbook of Organic Photochemistry and Pho
Autism and its Medical Management explains the medical aspects of autism and how both parents and professionals can use current medical knowledge to better understand how to address the medical aspects of autism. The book begins with an overview of Autism Spectrum Disorders (ASDs) and how they are diagnosed, and goes on to identify the different types of autism and to describe relevant medical interventions. The author also provides an outline of recent research to enable parents and professionals to gain an understanding of the various factors that may contribute to the development of ASDs, as well as the latest available treatment options. Bridging the communication gap between medical professionals and parents, this book offers accessible explanations of medical terminology and treatment relevant to ASDs and is an important tool for parents and professionals working with children with ASDs.
Written by top practitioners in the field of neuropsychological screening, Screening for Brain Impairment is the extensively updated new edition of the classic resource. Valuable to a broad range of medical and mental health practitioners, this new edition reflects enormous changes to the field over the past 13 years. Each chapter contains updated information and new empirical data, including extensive information on neurological and psychiatric disorders, adult attention deficit disorder, and screening for and assessing the emotional correlates of brain impairment. Also included are new chapters on computerized assessment and developing relations with other professionals, including clinical neuropsychologists, neurologists, primary care physicians, neurosurgeons, and psychiatrists.
This book is a culmination of the authors' carefully detailed but succinct revision notes which have been successfully used for the OMFS membership / board exams. It is a concise and easy-to-read book which covers all aspects of Oral & Maxillofacial Surgery, specifically with an examination approach in mind. This has been updated by the three authors with a strong pedigree of publication, teaching and research. An invaluable resource to any clinician related to the field of head and neck surgery, as well as for trainees who want to improve their knowledge, understanding and a quick revision guide for exams.
This Second Edition is the premier name resource in the field. It provides a handy resource for navigating the web of named reactions and reagents. Reactions and reagents are listed alphabetically, followed by relevant mechanisms, experimental data (including yields where available), and references to the primary literature. The text also includes three indices based on reagents and reactions, starting materials, and desired products. Organic chemistry professors, graduate students, and undergraduates, as well as chemists working in industrial, government, and other laboratories, will all find this book to be an invaluable reference.
Environmental Consequences and Management of Coastal Industries: Terms and Concepts covers the engineering, natural and social sciences aspects related to coastal power plants and their operation and management. The book gives background to featured problems and solutions, making it relevant to power plants in all global situations and giving practitioners what they need to assess environmental consequences. In addition, the book indicates, defines and illustrates the terms and concepts used worldwide. This is important as engineers and scientists often have an imperfect understanding of the requirements of each other, and similar (in some cases identical) terms may have very different meanings. Users will find this to be a simple and accessible guide to the terminology used and concepts covered. Individual entries are complete in themselves, but still cross referenced to other entries where additional information may be found. This provides quick-and-easy access to the required information. - Provides a unique approach that acts as a first-stop-shop for complementary interests with entries presented on separate pages - Presents multidisciplinary content, thus ensuring that different functions understand others' priorities and concerns - Includes comprehensive content with wide ranging coverage written by experts with many decades of experience in environmental aspects of coastal power plans and other industries
Written by surgical pathologists for surgical pathologists, Surgical Pathology of the Liver focuses on sharpening your skills and knowledge in diagnostic histopathology, including laboratory and clinical findings that are directly useful when evaluating liver histology for clinical care. It offers comprehensive, superbly illustrated coverage of general liver pathology, as well as several chapters on topics that are not often included in liver pathology textbooks. Abundant high-quality illustrations have been carefully chosen to support and extend the information given in the text.
Core Readings in Psychiatry, Second Edition, stands as an essential text for the academic. The contributors are distinguished experts who have a firm grasp of the relevant and classical citations in specific areas of psychiatry. In the intervening 8 years since the first edition, the profession's knowledge base has changed immensely. Included in this second edition are numerous citations and new topics such as AIDS, neuropsychiatry, models of psychoanalytic thought, child development, and medical economics. The book will open bibliographic doors for the academician as well as for the provider, manager, and consumer of psychiatric services and knowledge. It is designed to be an introduction and guide to the entire psychiatric literature.
The career of the expatriate director is re-examined through an analysis of: King and Country, The Servant, Accident, The Go-Between and the Romantic Englishwoman. Concerned with the abuse of power inherent in intimate relationships, he examined its manifestations in institutions and social classes as well.
Presents the most innovative results in carbene chemistry, setting the foundation for new discoveries and applications The discovery of stable carbenes has reinvigorated carbene chemistry research, with investigators seeking to develop carbenes into new useful catalysts and ligands. Presenting the most innovative and promising areas of carbene research over the past decade, this book explores newly discovered structural, catalytic, and organometallic aspects of carbene chemistry, with an emphasis on new and emerging synthetic applications. Contemporary Carbene Chemistry features contributions from an international team of pioneering carbene chemistry researchers. Collectively, these authors have highlighted the most interesting and promising areas of investigation in the field. The book is divided into two parts: Part 1, Properties and Reactions of Carbenes, explores new findings on carbene stability, acid-base behavior, and catalysis. Carbenic structure and reactivity are examined in chapters dedicated to stable carbenes, carbodicarbenes, carbenes as guests in supramolecular hosts, tunneling in carbene and oxacarbene reactions, and ultrafast kinetics of carbenes and their excited state precursors. Theoretical concerns are addressed in chapters on computational methods and dynamics applied to carbene reactions. Part 2, Metal Carbenes, is dedicated to the synthetic dimensions of carbenes, particularly the reactions and catalytic properties of metal carbenes. The authors discuss lithium, rhodium, ruthenium, chromium, molybdenum, tungsten, cobalt, and gold. All the chapters conclude with a summary of the current situation, new challenges on the horizon, and promising new research directions. A list of key reviews and suggestions for further reading also accompanies every chapter. Each volume of the Wiley Series on Reactive Intermediates in Chemistry and Biology focuses on a specific reactive intermediate, offering a broad range of perspectives from leading experts that sets the stage for new applications and further discoveries.
Use this atlas-style guide to master implant procedures and techniques! Written by leading expert Michael S. Block, DMD, Color Atlas of Dental Implant Surgery, 3rd Edition provides clear, full-color clinical photos and practical instructions covering a wide range of implant challenges. It takes you through treatment planning, presurgical guidelines, detailed surgical techniques, and postoperative follow-up. This edition adds more case studies and coverage of computed tomography. With this book, you'll be able to address any implant-related situation and achieve optimal results! - Clear step-by-step procedures include indications, contraindications, and treatment results for each procedure. - Over 1,400 full-color photographs and drawings depict important concepts and techniques, and show treatment from beginning to end. - Indications and contraindications for each procedure provide details of why a procedure is performed. - A discussion of the result of prosthodontic treatment is provided for each case, explaining how implant placement factors into successful therapy. - Chapters are organized by oral anatomy and surgical technique, with each chapter presenting a different area of the mouth or a specific surgical technique. - The Mandible section covers various approaches to augmentation of the atrophic mandible, including a case that utilizes distraction osteogenesis. - Detailed cases of posterior mandible surgery demonstrate onlay bone harvesting and grafting the deficient ridge. - The Maxilla section features sinus grafting, hard and soft tissue procedures, and the relatively new zygomaticus implant procedure. - References are provided at the end of every chapter for additional reading and research.
Kommentierte Bibliografie. Sie gibt Wissenschaftlern, Studierenden und Journalisten zuverlässig Auskunft über rund 6000 internationale Veröffentlichungen zum Thema Film und Medien. Die vorgestellten Rubriken reichen von Nachschlagewerk über Filmgeschichte bis hin zu Fernsehen, Video, Multimedia.
Magnetic Resonance Neuroimaging is a comprehensive volume that focuses on the newest fields of MRI from functional and metabolic mapping to the latest applications of neuro-interventional techniques. Each chapter offers critical discussions regarding available methods and the most recent advances in neuroimaging, including such topics as the use of diffusion and perfusion MRI in the early detection of stroke, the revolutionary advent of high-speed MRI for non-invasively mapping cortical responses to task activation paradigms, and the principles and applications of contrast agents. The chapters also discuss how these new advances are applied to problems in patients ranging in age from the newborn to the elderly, as well as disease states ranging from metabolic encephalopathy to cardiovascular disorders and stroke. Magnetic Resonance Neuroimaging will be a valuable text/reference for residents, research fellows, and clinicians in radiology, neuroradiology, and magnetic resonance imaging.
Covering preventive, non-invasive, and natural treatments, Textbook of Natural Medicine, 4th Edition offers more than just alternative medicine. It promotes an integrated practice that can utilize natural medicine, traditional Western medicine, or a combination of both in a comprehensive, scientific treatment plan. Based on a combination of philosophy and clinical studies, Textbook of Natural Medicine helps you provide health care that identifies and controls the underlying causes of disease, is supportive of the body's own healing processes, and is considerate of each patient's unique biochemistry. Internationally known authors Joseph Pizzorno and Michael Murray include detailed pharmacologic information on herbs and supplements, plus evidence-based coverage of diseases and conditions to help you make accurate diagnoses and provide effective therapy. Comprehensive, unique coverage makes this book the gold standard in natural medicine. A scientific presentation includes the science behind concepts and treatments, and discusses Western medical treatments and how they can work with natural medicine in a comprehensive treatment plan; if natural medicine is not effective, this book recommends the Western treatment. Coverage of pharmacology of natural medicines includes the uses and potential dangers of nearly 80 herbal medicines, special nutrients, and other natural agents, addressing topics such as general information, chemical composition, history, pharmacology, clinical applications dosage, and toxicology. In-depth, evidence-based coverage of 73 diseases and conditions includes key diagnostic criteria, pathophysiology of diseases, and therapeutic rationales. Coverage of potential interactions between drugs, herbs, and supplements ensures the safest possible use for each of 79 herbs and supplements. Diagnostic procedures include practical, easy-to-follow descriptions of evidence-based techniques plus discussions of clinical application of diet analysis, food allergy testing, immune function assessment, fatty acid profiling, hair mineral analysis, and other diagnostic approaches. Common therapeutic modalities are described and reviewed, including botanical medicine, nutritional therapy, therapeutic fasting, exercise therapy, hydrotherapy, counseling, acupuncture, homeopathy, and soft tissue manipulation. Coverage of syndromes and therapies helps in understanding the underlying causes of diseases by discussing topics such as food reactions, functional toxicology, sports nutrition, stress management, and breathing pattern disorders. Coverage of the philosophy of natural medicine includes its history and background, with discussions of toxicity, detoxification, and scientific documentation of the healing actions of nature and natural substances. Internationally known authors Joseph Pizzorno and Michael Murray and more than 90 expert contributors provide material that is up to date, accurate, and informed. More than 10,000 research literature citations show that the content is based on science rather than opinions or anecdotes. 13 useful appendices offer quick lookup of frequently used charts, handouts, and information. New chapters are included on hot topics such as female infertility, medicinal mushrooms, natural products and quality control, pregnancy health and primary prevention, and Vitamin K; new appendices include a supplier certification questionnaire and cervical escharotics treatment. Thorough updates ensure that you use only the most current research and provide the most effective treatment of patients. Tabs in Specific Health Problems section separate more than 70 alphabetized diseases/conditions. One convenient volume replaces the cumbersome two-volume set for easy, convenient reference. Electronic access is available via Pageburst, making it easy to search topics, drugs, herbs and supplements, and diseases and conditions. Sold separately.
The Insider's Guide to Acing the Neurology Boards-- Written by Physicians Who Passed! Apply the proven First Aid formula for Neurology Board success! 4 STAR DOODY'S REVIEW! "This is a nice, concise review of high-yield neurology and psychiatry topics focused on preparing for neurology board examinations. It can easily be read or reviewed in a short period of time, and the tables and graphics are also helpful. 4 Stars."--Doody's Review Service First Aid for the Neurology Boards is a unique guide for success on the Neurology Boards, in-training exams, and recertification. You will find hundreds of frequently-tested facts based on feedback from students who just passed the exam along with mini-cases essential for oral board preparation.The books is written by recent test-takers and reviewed by top faculty so you know you are studying the most up-to-date, relevant information possible. Features Hundreds of high-yield facts, mnenomics, clinical images, and summary tables help you ace the boards and in-service exams Covers must-know neurology AND psychiatry topics in one complete volume Written by recent, successful test-takers and reviewed by faculty so you know you're studying the most relevant, up-to-date material possible Integrated mini-cases highlight frequently tested scenarios and classic patient presentations Great for in-service and board exams and the perfect refresher before recertification The Content You Need to Excel on the Boards: Guide to the ABPN Examination, Neurology Topics: Neuroanatomy, Neuropharmacology, Neuroimmunology, Neurodegenerative Disorders, Headache and Pain, Neuro-oncology, Neuro-ophthalomology and Neuro-otology, Stroke and Neurocritical Care, Neurological Infections, Neuromuscular Disease, Pediatric Neurology and Neurogenetics, Seizures, Epilepsy, and Sleep Disorders, Psychiatry Topics: Substance Abuse and Dependence, Delirium, Anxiety Disorders, Somatoform Disorders, Bipolar Disorder, Major Depressive Disorder, Primary Psychotic Disorders. Visit www.FirstAidfortheBoards.com and www.FirstAidTeam.com
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