The Collected (Almost) Works of Michael Timko.Volume II consists of a number of essays written over the past 50 or so years. These essays, some scholarly, some not so scholarly, reflect his interests in various subjects, some scholarly, some not so. Their publication in this volume is chiefly for the benefit of immediate family and dear friends. The author hopes that those who dip into the book will immerse themselves completely; in other words get wet. In the words of that famous philosopher: Enjoy.
ACT (acceptance and commitment therapy) can be applied to any psychological disorder that involves struggle with inner experiences. With over 300 randomized clinical trials supporting its effectiveness, ACT has seen rapid growth in popularity, and an increasing number of therapists are being trained in its use. As such, the demand for practical resources on providing ACT has never been greater. ACT in Steps is aimed at any therapist who wants to get familiar with ACT. Chapters walk therapists through a recommended sequence of ACT sessions, including creative hopelessness, control as the problem, acceptance, defusion, mindfulness, values, and committed action, and provide accompanying materials for clients. The book also provides information on assessment, case conceptualization, treatment planning, and intervention that therapists can use as a starting point for practicing ACT. Exercises and worksheets are included which will continue to be useful long after readers have achieved mastery of ACT. Designed to serve as a more structured framework from which therapists can learn and experiment with ACT concepts, ACT in Steps is suitable for anyone interested in applying ACT across a range of presentations, from graduate students seeing their first clients to clinicians with years of experience interested in learning about ACT for the first time.
A brand new collection of world-class supply chain design solutions… 3 authoritative books, now in a convenient e-format, at a great price! 3 authoritative eBooks deliver state-of-the-art guidance for designing and optimizing highly competitive global supply chains! This unique 3 eBook package will help you design state-of-the-art supply chains that deliver rapid, quantifiable, and sustainable competitive advantage. The Encyclopedia of Operations Management is the perfect single-volume "field manual" for every supply chain or operations management practitioner and student. Nearly 1,500 well-organized, up-to-date definitions cover every facet of supply chain design, planning, management, and optimization. Next, in Reinventing the Supply Chain Life Cycle, Marc J. Schniederjans and Stephen B. LeGrand show how to optimize supply chains throughout their entire lifecycle: creation, growth, maturity, and decline! Reflecting up-to-the-minute "in-the-trenches" experience and pioneering research, this book illuminates the complex transformational processes associated with managing complex supply chains that incorporate multiple products and services within ever-changing networks. They walk you through: starting, creating, and building new supply chains; realigning them for growth; adjusting to dynamic change, readjusting networks, building flexibility, and managing new risks. Next, they offer practical, realistic guidance for realigning "mature" supply chains, innovating, controlling costs; and smoothly managing declining demand. Throughout, they offer invaluable insights, tools, and examples for negotiation, performance measurement, anticipating change, improving agility, meeting commitments to social responsibility and the law; and more. Finally, in Supply Chain Network Design, four leading IBM and Northwestern University experts show how to use strategic supply chain network design to achieve dramatic new savings. They integrate rigorous principles and practical applications to help you select the right number, location, territory, and size of warehouses, plants, and production lines; and optimize the flow of all products through even the most complex global supply chain. You’ll find better ways to decide what (and where) to manufacture internally; and which products to outsource (and to whom). You’ll get help managing cost vs. service-level tradeoffs; using analytics to improve decision-making; and re-optimizing regularly for even more savings. Whatever your role in supply chain design, this collection will help you systematically optimize performance, customer value, and profitability. From world-renowned supply chain experts Arthur V. Hill, Marc J. Schniederjans, Stephen B. LeGrand, Michael Watson, Sara Lewis, Peter Cacioppi, and Jay Jayaraman
50th Anniversary Edition of the groundbreaking case-based pharmacotherapy text, now a convenient two-volume set. Celebrating 50 years of excellence, Applied Therapeutics, 12th Edition, features contributions from more than 200 experienced clinicians. This acclaimed case-based approach promotes mastery and application of the fundamentals of drug therapeutics, guiding users from General Principles to specific disease coverage with accompanying problem-solving techniques that help users devise effective evidence-based drug treatment plans. Now in full color, the 12th Edition has been thoroughly updated throughout to reflect the ever-changing spectrum of drug knowledge and therapeutic approaches. New chapters ensure contemporary relevance and up-to-date IPE case studies train users to think like clinicians and confidently prepare for practice.
This important volume commences with an overview of the modes of action of defensive secondary metabolites, followed by detailed surveys of chemical defense in marine ecosystems, the biochemistry of induced defense, plant-microbe interactions and medical applications. A chapter is also included covering biotechnological aspects of producing valuable secondary metabolites in plant cell and organ cultures. This is a comprehensive and fully updated new edition, edited by Professor Michael Wink and including contributions from many internationally acknowledged experts in the field.
The 50th volume of Progress in Botany appears in new guise. In cooperation with Springer-Verlag we have changed from the less attractive typewriter composition to the direct reproduction of a manuscript which was writ ten by means of a text editing system and produced by a laser printer. We, the editors, should like to take the appearance of Volume 50 as the occasion for a few short remarks. Our younger readers are perhaps not aware that our Book Series was founded in 1931 by Fritz von Wettstein, based on the following thoughts and considerations, aptly formulated by him in the Preface to the first volume. "One of the greatest dangers threatening progress in the science of botany is the absolutely unbelievable growth in volume of the literature. The quality of journals, books and individual works that are daily sent to us makes it impossible for anyone person to maintain a general view of the progress made in botany in all the specialized fields, let alone to find time for results from associated su bjects. For varying reasons, every botanist must find this state of matters insupportable. Let us endeavor, in the general interest, to retain a wide background of knowledge, and not become limited specialists. The vitally necessary connections between the specialized fields can only flourish, or even exist, if the general view of botany as a whole can be maintained.
Even before the publication of Darwin's Origin of Species, the perception of evolutionary change has been a tree-like pattern of diversification - with divergent branches spreading further and further from the trunk. In the only illustration of Darwin's treatise, branches large and small never reconnect. However, it is now evident that this view does not adequately encompass the richness of evolutionary pattern and process. Instead, the evolution of species from microbes to mammals builds like a web that crosses and re-crosses through genetic exchange, even as it grows outward from a point of origin. Some of the avenues for genetic exchange, for example introgression through sexual recombination versus lateral gene transfer mediated by transposable elements, are based on definably different molecular mechanisms. However, even such widely different genetic processes may result in similar effects on adaptations (either new or transferred), genome evolution, population genetics, and the evolutionary/ecological trajectory of organisms. For example, the evolution of novel adaptations (resulting from lateral gene transfer) leading to the flea-borne, deadly, causative agent of plague from a rarely-fatal, orally-transmitted, bacterial species is quite similar to the adaptations accrued from natural hybridization between annual sunflower species resulting in the formation of several new species. Thus, more and more data indicate that evolution has resulted in lineages consisting of mosaics of genes derived from different ancestors. It is therefore becoming increasingly clear that the tree is an inadequate metaphor of evolutionary change. In this book, Arnold promotes the 'web-of-life' metaphor as a more appropriate representation of evolutionary change in all lifeforms. This research level text is suitable for senior undergraduate and graduate level students taking related courses in departments of genetics, ecology and evolution. It will also be of relevance and use to professional evolutionary biologists and systematists seeking a comprehensive and authoritative overview of this rapidly expanding field.
How to Scale-Up a Wet Granulation End Point Scientifically provides a single-source devoted to all relevant information on the scale-up of a wet granulation end point. Contents include a general description, problem identification, and theoretical background with supporting literature, case studies, potential solutions, and more. By outlining issues related to scale-up and end-point determination, and then using practical examples and advice to address these issues, How to Scale-Up a Wet Granulation End Point Scientifically is a valuable and essential resource for all those pharmaceutical scientists and technologists engaged in the granulation process. - Thoroughly referenced and based on the latest research and literature - Part of the Expertise in Pharmaceutical Process Technology Series edited by internationally respected expert, Michael Levin - Illustrates the most common problems related to scale-up of a wet granulation end point and provides valuable insights on how to solve these problems in a practical way
This groundbreaking two-volume handbook provides a comprehensive collection of evidence-based analyses of the causes, treatment, and prevention of eating disorders. A two-volume handbook featuring contributions from an international group of experts, and edited by two of the leading authorities on eating disorders and body image research Presents comprehensive coverage of eating disorders, including their history, etiological factors, diagnosis, assessment, prevention, and treatment Tackles controversies and previously unanswered questions in the field Includes coverage of DSM-5 and suggestions for further research at the end of each chapter 2 Volumes
A landmark contribution to chronic pain literature, this contemporary text measures the intricate relationship between chronic pain and life transition events. Researchers and clinicians will appreciate The Changing Nature of Pain Complaints Over the Lifespan for its linking of life transition theories to health and illness. Drawing on nearly 20 years of research, the authors bring together the epidemiological and psychosocial aspects of chronic pain and suggest expanding options for pain management. Their coverage encompasses every stage of the human life cycle.
This work provides a comprehensive overview of, and the most common and useful methods for, the synthesis of non-alpha-amino acids, particularly amino acids that are key synthetic intermediates or important compounds in their own right. Attention is paid to acyclic amino acids C3-C10 including amino alkanoic carboxylic acids, aminoalkenoic acids and aminoalkynoic acids.
Psychology Around Us, Fourth Canadian Edition offers students a wealth of tools and content in a structured learning environment that is designed to draw students in and hold their interest in the subject. Psychology Around Us is available with WileyPLUS, giving instructors the freedom and flexibility to tailor curated content and easily customize their course with their own material. It provides today's digital students with a wide array of media content — videos, interactive graphics, animations, adaptive practice — integrated at the learning objective level to provide students with a clear and engaging path through the material. Psychology Around Us is filled with interesting research and abundant opportunities to apply concepts in a real-life context. Students will become energized by the material as they realize that Psychology is "all around us.
Curiosity about the human mind—what it is and how it functions—began long before modern psychology. But because the mind and its processes are so elusive, they could be described only by means of metaphor. Michael Kearns, in this prize-winning study, examines the development of metaphors of the mind in psychological writings from Hobbes through William James and in fiction from Defoe through Henry James. Throughout the eighteenth century and even into the early nineteenth, metaphors of the mind as a relatively simple entity, either mechanical or biological, dominated both those engaged in psychological theorizing and novelists ranging from Richardson and Smollett through Dickens and the Brontes. In the nineteenth century, such psychologists as Herbert Spencer and Alexander Bain conceived of the mind as a complex organism quite different from that embodied in earlier thinking, but their figurative language did not keep pace. The result was a tension between theoretical expression and actual discussion of mental phenomena
This book describes the important role that the transfer of genes between organisms has played during the origin and evolution of humans, and the evolution of organisms on which the human species depends for shelter, sustenance and companionship.
An unlikely lothario, one of the most successful writers of his time, a figure at the heart of the age's political and artistic debates—H. G. Wells' life is a great story in its own right When H. G. Wells left school in 1880 at 13 he seemed destined for obscurity—yet he defied expectations, becoming one of the most famous writers in the world. He wrote classic science-fiction tales such as The Time Machine, The Invisible Man, and The War of the Worlds; reinvented the Dickensian novel in Kipps and The History of Mr Polly; pioneered postmodernism in experimental fiction; and harangued his contemporaries in polemics which included two bestselling histories of the world. He brought equal energy to his outrageously promiscuous love life—a series of affairs embraced distinguished authors such as Dorothy Richardson and Rebecca West, the gun-toting travel writer Odette Keun, and Russian spy Moura Budberg. Until his death in 1946 Wells had artistic and ideological confrontations with everyone from Henry James to George Orwell, from Churchill to Stalin. He remains a controversial figure, attacked by some as a philistine, sexist, and racist, praised by others as a great writer, a prophet of globalization, and a pioneer of human rights. Setting the record straight, this authoritative biography is the first full-scale account to include material from the long-suppressed skeleton correspondence with his mistresses and illegitimate daughter.
The American Society of Addiction Medicine Handbook of Addiction Medicine is a practical, evidence-based guide to the identification and treatment of substance use disorders. It includes chapters on specific substances with practical tools and treatment protocols. It also covers general topics including screening and brief intervention and psychiatric co-occurring disorders.
This unique multidisciplinary 8-volume set focuses on the emerging issues concerning synthesis, characterization, design, manufacturing and various other aspects of composite materials from renewable materials and provides a shared platform for both researcher and industry. The Handbook of Composites from Renewable Materials comprises a set of 8 individual volumes that brings an interdisciplinary perspective to accomplish a more detailed understanding of the interplay between the synthesis, structure, characterization, processing, applications and performance of these advanced materials. The Handbook comprises 169 chapters from world renowned experts covering a multitude of natural polymers/ reinforcement/ fillers and biodegradable materials. Volume 5 is solely focused on 'Biodegradable Materials'. Some of the important topics include but not limited to: Rice husk and its composites; biodegradable composites based on thermoplastic starch and talc nanoparticles; recent progress in biocomposites of biodegradable polymer; microbial polyesters: production and market; biodegradable and bioabsorbable materials for osteosynthesis applications; biodegradable polymers in tissue engineering; composites based on hydroxyapatite and biodegradable polylactide; biodegradable composites; development of membranes from biobased materials and their applications; green biodegradable composites based on natural fibers; fully biodegradable all-cellulose composites; natural fiber composites with bioderivative and/or degradable polymers; synthetic biodegradable polymers for bone tissue engineering; polysaccharides as green biodegradable platforms for building up electroactive composite materials; biodegradable polymer blends and composites from seaweeds; biocomposites scaffolds derived from renewable resources for bone tissue repair; pectin-based composites; recent advances in conductive composites based on biodegradable polymers for regenerative medicine applications; biosynthesis of PHAs and their biomedical applications; biodegradable soy protein isolate/poly(vinyl alcohol) packaging films; and biodegradability of biobased polymeric materials in natural environment.
The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: More than 25,000 references to the literature to facilitate further research Revised mechanisms, where required, that explain concepts in clear modern terms Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries A revised Appendix B to facilitate correlating chapter sections with synthetic transformations
In this updated edition of Substance Abuse and the Family, Michael D. Reiter examines addiction through a family systems lens which considers a range of interconnected contexts, such as biology and genetics, family relationships, and larger systems. Chapters are organized around two sections: Assessment and Treatment. Examining how the family system organizes around substance use and abuse, the first section includes contributions on the neurobiology and genetics of addiction, as well as chapters on family diversity, issues in substance-using families, and working in a culturally sensitive way. The second half of the book explores various treatment options for individuals and families presenting with substance abuse issues, providing an overview of the major family therapy theories, and chapters on self-help groups and the process of family recovery. The second edition has many useful additions including a revision of the family diversity chapter to consider sexual and gender minorities, brand new chapters on behavioral addictions such as sex and gambling, and a chapter on ethical implications in substance abuse work with families. Additional sections include information on Multisystemic Therapy, Behavioral Couples Therapy, Motivational Interviewing, and Twelve-Step Facilitation. Each chapter now contains a case application to help demonstrate treatment strategies in practice. Intended for undergraduate and graduate students, as well as beginning practitioners, Substance Abuse and the Family, 2nd Ed. remains one of the most penetrating and in-depth examinations on the topic available.
Current and future managers are regularly confronted with decisions that create risk in the legal environment of business. This book provides a framework for qualifying legal risk and then determining if the legal risk is worth taking. This framework begins by looking at the relationship between the firm, its suppliers, customers, owners, agents, and others in society as a whole to understand specific risks in personal injury, agreements, products, borrowing money, employees, independent contractors, and business entity selection. When the manager is aware of the magnitude of the risk and the likelihood of the risk, the manager is in a strong position to determine if the risk is worth taking. This book uses numerous applications from Game Theory to determine how risks of the firm compare to risks of another firm, an employee, a vendor and a customer. Students of business law will appreciate the black letter legal discussions of civil procedure, torts, contracts, the sale of goods, secured transactions, agency, and business associations with tax implications. Aspiring accounting students will find familiarity with many topics that appear on the AICPA exam. Managers will gravitate toward specific guidance with regard to setting up agreements with customers and vendors, creating effective human relations policies, and mitigating firm risks with regard to internal and external stakeholders. Dozens of managers provided input and experience that found its way into the selection of examples in the book ensuring real-world application for many practical business law problems.
Nanotechnology: The Future is Tiny introduces over a hundrerd specific research projects that are currently being investigated in laboratories distributed throughout the world.
Although less common than a-amino acids, non-a-amino acids-where the amino group is not on the carbon immediately adjacent to the carboxyl group but is attached to another carbon in the chain (for example, the , d carbon)-are components of biologically important molecules, are significant in the pharmaceutical industry, and are useful starting ma
On fire for God--a sweeping history of puritanism in England and America Begun in the mid-sixteenth century by Protestant nonconformists keen to reform England's church and society while saving their own souls, the puritan movement was a major catalyst in the great cultural changes that transformed the early modern world. Providing a uniquely broad transatlantic perspective, this groundbreaking volume traces puritanism's tumultuous history from its initial attempts to reshape the Church of England to its establishment of godly republics in both England and America and its demise at the end of the seventeenth century. Shedding new light on puritans whose impact was far-reaching as well as on those who left only limited traces behind them, Michael Winship delineates puritanism's triumphs and tribulations and shows how the puritan project of creating reformed churches working closely with intolerant godly governments evolved and broke down over time in response to changing geographical, political, and religious exigencies.
This social and cultural history of seventeenth-century Bermuda recounts the colony's development under the Virginia and Bermuda companies, with particular emphasis on how multiracial, multicultural interaction, a distinct maritime island environment, a pervasive Puritan religious culture, and thickening ties with other Anglo-American colonies created a distinctive new American-Bermudian identity. Puritanism, slavery, family tobacco farming, overcrowding, and out-migration shaped Bermuda's development and a growing network of Atlantic linkages that islanders formed that primed it to become a major maritime hub in the age of sail"--
Biosensor technology has rapidly expanded into a wide variety of applications in the last few years. This book focuses on several aspects of neural behavior both in vitro and in vivo, and for the first time, the detection of populations of neurons is presented.
This book shows that digitally assisted analog to digital converters are not the only way to cope with poor analog performance caused by technology scaling. It describes various analog design techniques that enhance the area and power efficiency without employing any type of digital calibration circuitry. These techniques consist of self-biasing for PVT enhancement, inverter-based design for improved speed/power ratio, gain-of-two obtained by voltage sum instead of charge redistribution, and current-mode reference shifting instead of voltage reference shifting. Together, these techniques allow enhancing the area and power efficiency of the main building blocks of a multiplying digital-to-analog converter (MDAC) based stage, namely, the flash quantizer, the amplifier, and the switched capacitor network of the MDAC. Complementing the theoretical analyses of the various techniques, a power efficient operational transconductance amplifier is implemented and experimentally characterized. Furthermore, a medium-low resolution reference-free high-speed time-interleaved pipeline ADC employing all mentioned design techniques and circuits is presented, implemented and experimentally characterized. This ADC is said to be reference-free because it precludes any reference voltage, therefore saving power and area, as reference circuits are not necessary. Experimental results demonstrate the potential of the techniques which enabled the implementation of area and power efficient circuits.
There are a few remaining wild places in Texas, notes author and nature educator Michael A. Smith, and exposure to these locales—from the high deserts and mountains of the Big Bend to the prairies and grasslands across the center of the state and the Piney Woods and Big Thicket of East Texas—can be restorative, both emotionally and physically. In this thoughtful tour of Texas ecoregions, Smith—also a licensed psychological associate—weaves perceptive prose, prompts, and meditations with evocative nature photography by Meghan Cassidy to create a guide for readers that promotes both greater appreciation of Texas nature and greater mindfulness of our place in the natural environment and its holistic importance to our wellbeing. Mindfulness in Texas Nature briefly explores the history of seven Texas ecoregions and discusses the benefits to health and wellbeing that are gained by spending time in nature. Written for readers who may not have a technical background in biology but who want to understand and experience nature at a deeper level, this book models mindfulness—experiencing oneself and surroundings in a fully-present, attuned, and nonjudgmental way—as an ideal practice for experiencing the woods, mountains, or wetlands of Texas. Illustrated throughout with beautiful photographs of woodlands, prairies, streams, flowers, and animals, Mindfulness in Texas Nature encourages readers to experience for themselves what makes these places special, how to get the most out of the time spent there, and how to plan meaningful visits to the many beautiful and significant natural areas across Texas.
In an exploration of the oceanic connections of the Atlantic world, Michael J. Jarvis recovers a mariner's view of early America as seen through the eyes of Bermuda's seafarers. The first social history of eighteenth-century Bermuda, this book profiles how one especially intensive maritime community capitalized on its position "in the eye of all trade." Jarvis takes readers aboard small Bermudian sloops and follows white and enslaved sailors as they shuttled cargoes between ports, raked salt, harvested timber, salvaged shipwrecks, hunted whales, captured prizes, and smuggled contraband in an expansive maritime sphere spanning Great Britain's North American and Caribbean colonies. In doing so, he shows how humble sailors and seafaring slaves operating small family-owned vessels were significant but underappreciated agents of Atlantic integration. The American Revolution starkly revealed the extent of British America's integration before 1775 as it shattered interregional links that Bermudians had helped to forge. Reliant on North America for food and customers, Bermudians faced disaster at the conflict's start. A bold act of treason enabled islanders to continue trade with their rebellious neighbors and helped them to survive and even prosper in an Atlantic world at war. Ultimately, however, the creation of the United States ended Bermuda's economic independence and doomed the island's maritime economy.
Instant New York Times Bestseller Uncover the evidence-based science to slowing the effects of aging, from the New York Times bestselling author of the How Not to Die series When Dr. Michael Greger, founder of NutritionFacts.org, dove into the top peer-reviewed anti-aging medical research, he realized that diet could regulate every one of the most promising strategies for combating the effects of aging. We don’t need Big Pharma to keep us feeling young—we already have the tools. In How Not to Age, the internationally renowned physician and nutritionist breaks down the science of aging and chronic illness and explains how to help avoid the diseases most commonly encountered in our journeys through life. Physicians have long treated aging as a malady, but getting older does not have to mean getting sicker. There are eleven pathways for aging in our bodies’ cells and we can disrupt each of them. Processes like autophagy, the upcycling of unusable junk, can be boosted with spermidine, a compound found in tempeh, mushrooms, and wheat germ. Senescent “zombie” cells that spew inflammation and are linked to many age-related diseases may be cleared in part with quercetin-rich foods like onions, apples, and kale. And we can combat effects of aging without breaking the bank. Why spend a small fortune on vitamin C and nicotinamide facial serums when you can make your own for up to 2,000 times cheaper? Inspired by the dietary and lifestyle patterns of centenarians and residents of “blue zone” regions where people live the longest, Dr. Greger presents simple, accessible, and evidence-based methods to preserve the body functions that keep you feeling youthful, both physically and mentally. Brimming with expertise and actionable takeaways, How Not to Age lays out practical strategies for achieving ultimate longevity.
The second edition of Ventilation Control of the Work Environment incorporates changes in the field of industrial hygiene since the first edition was published in 1982. Integrating feedback from students and professionals, the new edition includes problems sets for each chapter and updated information on the modeling of exhaust ventilation systems, and thus assures the continuation of the book's role as the primary industry textbook. This revised text includes a large amount of material on HVAC systems, and has been updated to reflect the changes in the Ventilation Manual published by ACGIH. It uses both English and metric units, and each chapter concludes with a problem set.
Most observers believe that gospel music has been sung in African-American churches since their organization in the late 1800s. Yet nothing could be further from the truth, as Michael W. Harris's history of gospel blues reveals. Tracing the rise of gospel blues as seen through the career of its founding figure, Thomas Andrew Dorsey, Harris tells the story of the most prominent person in the advent of gospel blues. Also known as "Georgia Tom," Dorsey had considerable success in the 1920s as a pianist, composer, and arranger for prominent blues singes including Ma Rainey. In the 1930s he became involved in Chicago's African-American, old-line Protestant churches, where his background in the blues greatly influenced his composing and singing. Following much controversy during the 1930s and the eventual overwhelming response that Dorsey's new form of music received, the gospel blues became a major force in African-American churches and religion. His more than 400 gospel songs and recent Grammy Award indicate that he is still today the most prolific composer/publisher in the movement. Delving into the life of the central figure of gospel blues, Harris illuminates not only the evolution of this popular musical form, but also the thought and social forces that forged the culture in which this music was shaped.
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