This canon of French literature, Honore de Balzac (1799-1850) is also a major European figure in the development of realism. His work is dominated by an inter-related sequence of novels and short stories, La Comedie Humanine, which charts the idiosyncrasies of French society from the beginning of the nineteenth century to the 1840's. Among the most famous of these are Le Pierre Goriot and La Cousine Bette. Iin this study, Dr Tilby concentrates on the main approaches in practice and discusses some of the earliest responses to Balzac's work. His introduction and headnotes set Balzac's work in context. This book will be of interest to students of French language and literature and also to those studying French in combined studies or humanities courses.
The Avengers and the X-Men are faced with a common foe that becomes their greatest threat: Wanda Maximoff! The Scarlet Witch is out of control, and the fate of the entire world is in her hands. Will Magneto help his daughter or use her powers to his own benefit? Starring the Astonishing X-Men and the New Avengers! You know how sometimes you hear the phrase: and nothing will ever be the same again? Well, this time believe it, buster! Nothing will ever be the same again! Collects House of M (2005) #1-8.
A collection of 6 volumes of Oakeshott's work: Notebooks, 1922-86, Early Political Writings 1925-30, The Concept of a Philosophical Jurisprudence, Vocabulary of a Modern European State, Lectures in the History of Political Thought, and What is History?
This volume brings together for the first time over a hundred of Oakeshott's essays and reviews, written between 1926 and 1951, that until now have remained scattered through a variety of scholarly journals, periodicals and newspapers. A new editorial introduction explains how these pieces, including the lengthy essay on the philosophical nature of jurisprudence that occupies an important position in Oakeshott's work, illuminate his other published writings. The collection throws new light on the context of his thought by placing him in dialogue with a number of other major figures in the humanities and social sciences during this period, including Leo Strauss, A.N. Whitehead, Karl Mannheim, Herbert Butterfield, E.H. Carr, Gilbert Ryle, and R.G. Collingwood.
TOWARDS THE LIGHT: GROWING THROUGH GRIEF is a remarkable book. A practical handbook of coming to terms with grief, it is also a rare insight into a personal journey which still continues following the death not only of the author's father but his son. As you face up to your unique grief it is helpful to know the landscape which you are likely to travel. This map is outlined with compassion and wisdom in the first part of the book. Surviving different types of death is specified in the second part of the book and a spiritual guide follows in the third.
The first comprehensive textbook on the theology and methodology of Fresh Expressions, one of the most important developments within the contemporary church.
Stanley Hauerwas, was declared by "Time Magazine" in 2001 to be 'America's best theologian'. This book explores his work on the Church as a community living holiness. It offers an accessible introduction to Hauerwas' understanding of the ethics, character, narrative, practices and politics of the Church in late modern societies. Hauerwas has lots of imaginative, challenging and creative things to say. This book seeks to make them more available to the wider Church and its clergy at ground level. Section I introduces Hauerwas' work on the Church. It critically explores the importance he places on the church, its story and its politics as witness to the reign of God in the world. Section II demonstrates how Hauerwas' thinking can illuminate congregational life, discipleship, Scripture, mission, theology and witness in fresh and encouraging ways.
Taking account of the significant developments in practice and thinking around the emerging church, this book will quickly establish itself as a key text for all interested in pioneer ministry, fresh expressions, church planting, church growth and ecclesiology.
This book is about the so called “4S” challenge – how does or can or should someone say something to someone about something? This challenge is getting more intense day by day in our contemporary globalized world, increasingly connected by science and technology through telecommunication and all sorts of social media, where people are acutely aware of the diverse views on culture, politics, economics, religion, ethics, education, physical health and mental wellbeing, which are very often in conflicts with each other. This book arises from the reading of the dialogue between two internationally renowned and respected French scholars, Jean-Pierre Changeux and Paul Ricoeur, What Makes Us Think? A Neuroscientist and a Philosopher Argue about Ethics, Human Nature, and the Brain, which explores where science and philosophy meet, and whether there is a place for religion in the 21st century. This book develops on the ideas Ricoeur raised in the dialogue about the need for “digging deeper” and a “third discourse” as a way forward to improve dialogues between competing worldviews and ideologies. It attempts to formulate a “third discourse” (as distinct from ordinary language as “first discourse” and various scientific or professional/specialist languages as “second discourse”) to address the burning issue of fragmentation of the person through overcoming the alienations between established discourses of philosophy, science and theology, without doing injustice to the unique and indispensable contributions of each of these discourses. It argues that such a “third discourse” has to go beyond dualism and reductionism. To achieve that, this new way of talking about the lived experience of the person is going to take the form of a non-reductive correlative multilayered discourse that has the capacity to, as expressed in the language of the hermeneutics of Ricoeur, “explain more in order to understand better.”
This book is based on the papers presented at the conference on "Mecha nisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment," held at the National Bureau of Standards on June 2-7, 1985, This volume deals with mechanisms of DNA damage and repair at the molecular level; consequences of unrepaired or misrepaired damage, with major emphasis on carcinogenesis; drugs which bind selectively to altered and potentially damaging DNA sequences; and potential utilization of DNA damage as an endpoint for assessing risks of UV light, ionizing radiations, chemicals, drugs, and hazardous agents in foods. Because the induction of mutations by radiation and genotoxic chemicals has been observed to follow one-hit kinetics in some instances, it is generally assumed that any level of exposure to a DNA-damaging agent may increase the risk of genetic disease or cancer in an exposed population. At the same time, however, there is evidence that although the DNA of living cells is continually damaged by natural background radiation, free radicals, and other naturally occurring processes, most of the damage is normally repaired.
Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease. Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy. The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.
Originating in the prestigious Joanne Goodman Lecture Series, this book explores the foundations of medicine through three case studies that elucidate turning points in the evolution of health care.
With eyewitness accounts and contemporary reports—linked together by succinct analytical commentaries—Richard Hofstadter and his young collaborator, Michael Wallace, have created a superb documentary reader that is, in effect, a history of violence in America through four centuries. Here, as experienced by men and women who lived through them, are not only the familiar, chilling eruptions—Harper’s Ferry; the Civil War draft riot in New York; Homestead; Centralia; the Detroit ghetto; the assassinations of Lincoln, Malcolm X, and Robert Kennedy—but also less commonly remembered episodes, such as the New York slave riots of 1712, the doctors’ riot of 1788, vigilante terror in Montana, the anti-Chinese riot in Los Angeles in 1871, and the White League coup d’état of 1874 in New Orleans. In his extensive introduction, Richard Hofstadter shows how, in the face of the record, Americans have had an extraordinary ability to persuade themselves that they are among the best-behaved and the best-regulated of peoples. With more than one hundred entries, the editors have documented and put into perspective the thread of violence in American history whose rediscovery—as Hofstadter suggests—will undoubtedly be one of the most important intellectual legacies of the 1960’s. The book clearly demonstrates, even as the reader comes to grips with long-eluded truths, that America’s consistent history of violence has not yet breached beyond hope of restoration our long record of basic political stability, that most social reforms in the United States have been brought about without violence.
The definitive guide to the clinical and scientific aspects of pulmonary medicine―fully updated with the latest advances in the field A Doody's Core Title for 2023! Fishman’s Pulmonary Diseases and Disorders delivers unparalleled coverage of pulmonary medicine. With nearly 2500 illustrations, 60 videos, and 22,000 references, this peerless, two-volume resource provides a comprehensive overview of the scientific basis of lung function in health and disease. You’ll find detailed coverage of the broad array of disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms, respiratory infections, and respiratory failure. In addition, you’ll learn about all the latest advances, including molecular development of the lung, stem cells and respiratory disease, the genetics of pulmonary disease, the growth of personalized medicine, technical advances in lung transplantation, and much more. Notable new content in the 6th edition includes discussion of the respiratory effects of vaping, detailed consideration of the idiopathic interstitial pneumonitides, state-of the-art discussion of lung nodules, a summary of the use of immunotherapy in the treatment of lung cancer, COVID-19-related lung disease and its management, and a comprehensive discussion of noninvasive ventilation, including its use in ambulatory and ICU settings. In addition, new chapters on cystic lung disease, lung cancer screening, the lung microbiome, developmental lung disorders, nocardiosis and actinomycosis, and application of ECMO are included.
Turn to the field's definitive text for a thoroughunderstanding of the clinical and scientific aspects of pulmonary medicine Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with 270 contributing authors, includes over 2,000 illustrations, 60 videos, and 18,000 references. The book opens with a comprehensive overview of the scientific basis of lung function in health and disease. It then provides detailed coverage of the broad array of diseases and disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms,respiratory infections, and respiratory failure, among others. The Fifth Edition has been completely updated to reflect the many advancements that have been made in pulmonary medicine over the past few years, including: Molecular development of the lung Stem cells and respiratory disease Genetics of pulmonary disease and the growth of personalized medicine Technical advances in lung transplantation Growth in immunology and immunosuppressive management Diagnosis and treatment of pulmonary hypertension Circadian rhythms and sleep biology Rapid evolution in lung imaging techniques, including functional imaging Contemporary interventional bronchoscopic techniques You will also find state-of-the-art coverage of thelatest topics in critical care medicine, including: Early diagnosis and management of sepsis Multiple organ dysfunction syndrome (MODS) Acute respiratory distress syndrome (ARDS) Management of agitation and delirium in the ICU The newly defined entity of "chronic critical illness
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