Michael A. Sullenger was born and raised in a small Southern Indiana town. Over the years, his travels and education, coupled with his Christian upbringing and his undergraduate and postgraduate studies, have cultivated his personal political views. Those views and observations are the focus of this book. His perspective is that of someone raised with Midwestern and Christian values, which he feels differs greatly from those on the East and West Coasts, as well as in most large cities. Those who have lived their lives through their school years and into early adulthood have a moral view of life and what it means to be a responsible citizen who contributes to our American society that clearly differs from the liberal members of our country. He asks straightforward questions that deal with our current political direction, from a Christian point of view. He also points out fallacies that are ever present in today's political system, along with challenging today's Christians to evaluate the politicians and political party they support against the biblical teachings in the Old and New Testament, as well as the Ten Commandments. If you find they fall short of those teachings, maybe a change is in order.
A Discipline Divided brings together the literature on the sociology of sociology and the research on the teaching of sociology to examine the ways in which historical, intellectual, and structural forces shaped the content and objectives of high school sociology courses between 1911 and 2001. Relying on questionnaire and interview data, published descriptions of past high school sociology courses, and current teachers' course materials, Michael DeCesare documents how teachers and sociologists have conceptualized the high school sociology course. On one hand, teachers have consistently taught social problems with an eye toward developing good citizens. On the other hand, sociologists have pushed for scientific sociology in the high school classroom, especially since the 1960s. A Discipline Divided points the way toward a new approach to the study of teaching-one that leads away from individualistic explanations for pedagogical decisions and toward an understanding of contextual and structural influences. Concluding with recommendations for bridging the historical gap between sociology teachers and academics, A Discipline Divided is a comprehensive and detailed study of the first sociology courses many students encounter, and an essential book for sociologists and education researchers.
Hampton County was carved from Beaufort County during the turmoil of Reconstruction and named for Gov. Wade Hampton, who personally laid the cornerstone for the county courthouse in 1878. The county's rich soil, abundant rivers, and lush pine forests make it a paradise for farmers and sportsmen. Locally manufactured products from Plywoods-Plastics Corporation were used on World War II battlefields, in Navy atomic submarines, and even in NASA space missions. The Hampton County Watermelon Festival, which has been held annually since 1939, is the state's oldest continuing festival, and it boasts the longest parade: 2.4 miles that encompasses two towns. The vintage photographic collection of Hampton County captivates readers with the history, hard work, natural beauty, and Southern charm of this Lowcountry community.
An integrated approach to the study of drug action mechanisms Biochemical Pharmacology is a concise and contemporary textbook on the principles of drug action. It discusses representative drugs by example to explore the range of biochemical targets and mechanisms. The book explains some of the experiments that tell us how drugs work, and it outlines the physiological and pathological context that make those action mechanisms therapeutically useful. Biochemical Pharmacology is intended primarily for students in biology and biochemistry at the advanced undergraduate or graduate levels. For classroom use, the illustrations from the book are separately available as PowerPoint slides. It is written in a conversational, vivid style that readily encourages students to explore this important area of medical science. Biochemical Pharmacology can also serve as an introduction for professionals in biosciences, as well as in pharmaceutical and health sciences. Complete with numerous figures throughout the text, which are also available separately as PowerPoint slides, Biochemical Pharmacology: Explains the role of pharmacodynamics, pharmacokinetics, and drug metabolism in drug action Provides representative examples from the pharmacology of cell excitation, hormones, nitric oxide, chemotherapy, and others Examines emerging applications of ribonucleic acids as drugs and drug targets Discusses what researchers need to know about the problems of drug distribution, elimination, and toxicity Biochemical Pharmacology is an important resource for anyone wishing to gain an in-depth understanding of drug action mechanisms and extremely useful for researchers wishing to explore some of the unanswered questions .
Science Teaching explains how history and philosophy of science contributes to the resolution of persistent theoretical, curricular, and pedagogical issues in science education. It shows why it is essential for science teachers to know and appreciate the history and philosophy of the subject they teach and how this knowledge can enrich science instruction and enthuse students in the subject. Through its historical perspective, the book reveals to students, teachers, and researchers the foundations of scientific knowledge and its connection to philosophy, metaphysics, mathematics, and broader social influences including the European Enlightenment, and develops detailed arguments about constructivism, worldviews and science, multicultural science education, inquiry teaching, values, and teacher education. Fully updated and expanded, the 20th Anniversary Edition of this classic text, featuring four new chapters—The Enlightenment Tradition; Joseph Priestley and Photosynthesis; Science, Worldviews and Education; and Nature of Science Research—and 1,300 references, provides a solid foundation for teaching and learning in the field.
Nanomedicine is a developing field, which includes different disciplines such as material science, chemistry, engineering and medicine devoted to the design, synthesis and construction of high-tech nanostructures. The ability of these structures to have their chemical and physical properties tuned by structural modification, has allowed their use in drug delivery systems, gene therapy delivery, and various types of theranostic approaches. Colloidal noble metal nanoparticles and other nanostructures have many therapeutic and diagnostic applications. The concept of drug targeting as a magic bullet has led to much research in chemical modification to design and optimize the binding to targeted receptors. It is important to understand the precise relationship between the drug and the carrier and its ability to target specific tissues, and pathogens to make an efficient drug delivery system. This book covers advances based on different drug delivery systems: polymeric and hyper branched nanomaterials, carbon-based nanomaterials, nature-inspired nanomaterials, and pathogen-based carriers.
Can life exist in the Antarctic ice, in the deep subsurface, in dilute sulfuric acid, in hot springs-even on Mars? What degree of high or low temperature, pressure, or salt concentration can living cells tolerate? In recent years, scientists have discovered many single-cell creatures that exist in-in fact, are perfectly adapted to-extreme environments that were considered uninhabitable just one or two decades ago. In Life on the Edge, author Michael Gross explores how microorganisms adapt to their hostile environments and how they affect our current definition of the "normal" conditions for life. He also describes the vast implications of these extremophiles and other amazing creatures-from potential breakthroughs in medicine and biotechnology to the search for life elsewhere in the universe.
Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease. Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy. The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.
A practical manual of protocols for achieving expression of foreign genes in mammalian cells. It includes some very new techniques such as PCR-based expression. The author gives a theoretical introduction to the protocols and compares the strengths and weaknesses.
The benchmark evidence-based pharmacotherapy text-now in full color! Additional chapters are available online When it comes to helping you develop a mastery of evidence-based medicine for optimal patient outcomes, no book can match Pharmacotherapy: A Pathophysiologic Approach. Like the discipline it covers, the scope of this trusted resource goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. The book also delves into psychosocial issues that affect compliance ... topics related to a patient's ability to understand and manage often-complex therapy... and lifestyle changes that may reduce the need for drug therapy or improve pharmacotherapeutic outcomes. Pharmacotherapy delivers everything you need to provide safe, efficacious drug therapy across the full range of therapeutic categories. FEATURES NEW! Expanded evidence-based recommendations NEW! Extended coverage of the timely issue of palliative care and pain medicine NEW! Important chapters on Pulmonary Hypertension, Disorders of Calcium and Phosphorus Homeostasis, and Multiple Myeloma, Outstanding pedagogy, including: “Key Concepts” highlighted in each chapter “Clinical Presentation” boxes summarize the most common disease signs and symptoms covered in each chapter “Clinical Controversies” boxes-presented in the Treatment sections of the disease-oriented chapters-examine the complicated issues faced by students and clinicians in providing drug therapy Clear therapeutic recommendations in each disease-specific chapter “Evaluation of Therapeutic Outcomes” boxes in each disease-specific chapter, containing key monitoring guidelines that facilitate the development of a pharmaceutical, nursing, or medical care plan
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