You want to know who gave you your immortal soul? You want a personal relationship with God? Well, we found God. We're all up in God. We've got God's private number. And so do you: imprinted a hundred trillion times – once in every living cell in your big dripping corpus.' So says a woman with a pole-axe pressed to her neck, and the solution to the entire mystery of human existence clutched between her palms. Two weeks earlier, she was just your average British expat with a PhD, working in Silicon Valley as an artificial intelligence designer for ultra-violent video games, spending the evenings hanging out with her pet chimp – and wondering how something as weird as human consciousness could have evolved through mere Darwinian selection. But when a mysterious and disconcertingly attractive behavioural geneticist, and a hotshot cryptologist with strange religious affiliations, stroll into her life, she begins looking for answers in the backwaters of the human genome – the 97% written off by scientists as ;junk DNA;. And soon after, when men in very strange hats come looking for her hard drive, shooting first and never really asking any questions, she finds herself on the run – pursued by multiple squads of heavily-armed religious zealots, the Feds, and worse. All seek to obtain, or to suppress forever, the key to the revelatory stretch of DNA known as The Pandora Sequence. The outcome of their race to control this explosive secret will forever alter how humanity regards itself - that is, if anyone lives long enough to tell the tale.
You want to know who gave you your immortal soul? You want a personal relationship with God? Well, we found God. We're all up in God. We've got God's private number. And so do you: imprinted a hundred trillion times – once in every living cell in your big dripping corpus.' So says a woman with a pole-axe pressed to her neck, and the solution to the entire mystery of human existence clutched between her palms. Two weeks earlier, she was just your average British expat with a PhD, working in Silicon Valley as an artificial intelligence designer for ultra-violent video games, spending the evenings hanging out with her pet chimp – and wondering how something as weird as human consciousness could have evolved through mere Darwinian selection. But when a mysterious and disconcertingly attractive behavioural geneticist, and a hotshot cryptologist with strange religious affiliations, stroll into her life, she begins looking for answers in the backwaters of the human genome – the 97% written off by scientists as ;junk DNA;. And soon after, when men in very strange hats come looking for her hard drive, shooting first and never really asking any questions, she finds herself on the run – pursued by multiple squads of heavily-armed religious zealots, the Feds, and worse. All seek to obtain, or to suppress forever, the key to the revelatory stretch of DNA known as The Pandora Sequence. The outcome of their race to control this explosive secret will forever alter how humanity regards itself - that is, if anyone lives long enough to tell the tale.
Two million dollars in a black bag. The meaning of life hidden on a deviously encrypted web site. And several dozen heavily armed guys with serious existential issues. The hunt is on for The Manuscript. The Manuscript is a philosophical cyber-thriller – a novel of huge ideas disguised as a blow-your-hair-back thrill ride. Its cast of unforgettable characters includes a gun-toting urban professional with a tragic weakness for Internet discussion groups; a former chemistry student and hacker turned wildly successful online narcotics dealer; a pair of slacker post-grads with big questions and rapidly escalating problems; a demonstrably unstoppable hitman; a dodgy federal agent with his hands in the cookie jar up to both elbows; a nameless cadre of menacing and well-armed mercenaries (possibly in the employ of one of the world's major religions); and an entire gang of Angry Young Taoists, serenely blasting hell out of all and sundry. What could bring a group like this together? Nothing less than the meaning of life – discovered in the remote highlands of South America by an infamous 19th-century explorer, and now said to be hidden in the vast out-of-bounds spaces at the far edge of a shadow Internet. This is the Manuscript. Caught up in a perilous race to recover and control it are a group of young people so beset by existential unease that they are willing to risk death to know the truth; and others, backed by powerful interests, who have little compunction about killing to keep it hidden. Get ready for an ungentle ride where a number of people will get enlightened, a few will get rich, and all too many will get dead. Along the way, be prepared for some uncommon commentary on the eternal verities, computer security, rules for gunfights, post-millennial information soot, and the possibility of human connection for a generation that believes in nothing – save what they read on the Net.
Adas explores the relationship between millenarianism and violent protest by focusing on five case studies representing a wide range of social, political, and economic systems. The rebellions examined are: Netherlands East Indies (1825-30), New Zealand (c. 1864-67), Central India (1895-1900), German East Africa (1903-6), and Burma (1930-32). Arranged topically to emphasize comparative patterns, the study analyzes causes, leaders, organization, failure, and the impact on the individual society. Originally published in 1979. A UNC Press Enduring Edition -- UNC Press Enduring Editions use the latest in digital technology to make available again books from our distinguished backlist that were previously out of print. These editions are published unaltered from the original, and are presented in affordable paperback formats, bringing readers both historical and cultural value.
Vegetarianism is not a diet trend, or the flavor of the month. Instead, it is a philosophy and practice with roots in antiquity. Vegetarianism has existed for centuries in much of the world as a social movement and subculture. In the United States, this subculture has existed for more than 200 years. In this book, the Iacobbos bring this thriving subculture to life. By examining its businesses, organizations, events, scholarship, and influence on the arts, and by interviewing dozens of vegetarians and vegans, the authors reveal a subculture whose members hold a variety of perspectives on everything from animal rights to advocacy, politics, and religion. Building upon their previous book, a history of vegetarianism, the Iacobbos delve into its current incarnations. They include information on the food industry, health studies on the benefits of vegetarians and vegan ways of eating, the popularity of vegetarianism, and the backlash against it. They highlight the work of vegetarian advocates and provide a glimpse of the stores, magazines, restaurants, and organizations that bring this subculture together. Finally, they include projections for the future from vegetarians, environmentalists, lawyers, nutritionists, economists, and experts in animal rights.
The essays collected in this volume, first published in 1998, address the profound changes and disruptions wrought in peasant societies as a result of European colonial domination and the spread of the capitalist world economy from its European base. Detailed case study evidence is included in the essays, and all are aimed at delineating broader patterns and addressing general questions and debates regarding peasant responses to the varied impact of colonialism and capitalism.
This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD). There is growing evidence that obsessive-compulsive symptoms in schizophrenia are prevalent, persistent and characterized by a distinct pattern of familial inheritance, neurocognitive deficits and brain activation. This text provides guidelines for differential diagnosis of schizophrenic patients with obsessive-compulsive symptoms, and patients with primary OCD alongside poor insight, psychotic features or schizotypal personality. Written by a leading expert in the coexistence of obsessive-compulsive and schizophrenic phenomena, Schizo-Obsessive Disorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management. The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners.
First published in 1998, this volume contains essays from leading thinkers on both sides of the Atlantic on the relationship between law and science. Science plays an ever-increasing part in the development of legislation and the adjudication of cases. Its limitations and its value are explored in these essays which discuss issues of methodology and of evidence. Amongst areas covered are silicone breast implants, the rape trauma syndrome, the environment, inventions and Bayesianism.
This book analyzes revenue management (RM) problems with flexible products and RM in broadcasting companies. It presents models and methods that explicitly take the implications of flexibility into account. In addition, it contains descriptions of algorithms to generate stochastic demand data streams for general RM problems. To help readers with their own simulation studies, it provides an implementation as a Microsoft Windows executable file.
Year Book of Pediatrics brings you abstracts of the articles that reported the year's breakthrough developments in pediatrics, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. Articles are selected to cover the full breadth of the specialty, from gastroenterology, hematology, adolescent medicine, allergy and immunology, to urology, neurology, and therapeutics and toxicology.The 2015 edition marks the reign of the new Editor, Dr. Michael Cabana.
Media history is his subject, and, as this memoir makes so delightfully clear, it has also been Erik Barnouw's life. Barnouw's story, told with wit and charm in Media Marathon, is the story of American culture adjusting to the twentieth century, of new media repeatedly displacing the old in a century-long competitive upheaval.
Two million dollars in a black bag. The meaning of life hidden on a deviously encrypted website. And several dozen heavily armed men with serious existential issues. The hunt is on for The Manuscript in this high-speed, action-packed thriller.
The best edition yet of the cornerstone text on abdominal operations—enhanced by thousands of full-color photographs and illustrations and thoroughly updated content A Doody’s Core Title for 2021! Edition after edition, Maingot’s Abdominal Operations has been hailed as the most complete, current, and trusted resource among general, colorectal, and gastrointestinal surgeons. Presented in full color, this classic textbook carefully details common and important abdominal procedures, offering a concise, yet complete, survey of the diagnosis and management of benign and malignant digestive disorders. Bolstered by more than 650 photographs and 1,250 full color illustrations, Maingot’s 78 chapters deliver everything you need to understand congenital, acquired, and neoplastic disorders – and optimize surgical outcomes for any type of abdominal disorder. FEATURES: Contemporary focus on operative procedures, and new concepts in the diagnosis and management of abdominal disease Convenient organ/procedure presentation provides a seamless review of surgical protocols, as well as pre- and postoperative strategies and techniques Added chapters on quality metrics, ERAS, and robotic surgery; and an increased number of “Perspective” commentaries by experts in the field Disease-focused and organ/procedure presentation provides a seamless review of surgical protocols, as well as pre- and postoperative strategies and techniques More than 650 photographs and 1,250 full color illustrations, many new to this edition
Recent determination of genome sequences for a wide range of bacteria has made in-depth knowledge of prokaryotic metabolic function essential in order to give biochemical, physiological, and ecological meaning to the genomic information. Clearly describing the important metabolic processes that occur in prokaryotes under different conditions and in different environments, this advanced text provides an overview of the key cellular processes that determine bacterial roles in the environment, biotechnology, and human health. Prokaryotic structure is described as well as the means by which nutrients are transported into cells across membranes. Glucose metabolism through glycolysis and the TCA cycle are discussed, as well as other trophic variations found in prokaryotes, including the use of organic compounds, anaerobic fermentation, anaerobic respiratory processes, and photosynthesis. The regulation of metabolism through control of gene expression and control of the activity of enzymes is also covered, as well as survival mechanisms used under starvation conditions.
Although few taxpayers and legislators care whether the nation's English professors are doing justice to identifying the beautiful and the sublime, conversely the image of English departments plays a major role in determining public attitudes toward colleges and college faculty. Investigating the ramifications of current debates, this book provides the clearest and most comprehensive account of this controversy to date.
THE DEFINITIVE ILLUSTRATED GUIDE TO ABDOMINAL OPERATIONS FOR GENERAL, COLORECTAL, AND GASTROINTESTINAL SURGEONS--NOW IN FULL COLOR! With each edition, Maingot's Abdominal Operations has built a legacy of expertise, currency, and clinical rigor acclaimed by surgical trainees and practicing surgeons. Presented in full-color for the first time, the 63 streamlined chapters of the twelfth edition offer a concise, yet complete, survey of the diagnosis and management of benign and malignant digestive diseases. This authoritative resource has everything you need to understand congenital, acquired, and neoplastic disorders--and optimize surgical outcomes for any type of abdominal procedure. FEATURES Contemporary focus on operative procedures, and new concepts in the diagnosis and management of abdominal disease Convenient organ/procedure presentation provides a seamless review of surgical protocols, as well as pre- and postoperative strategies and techniques Thirteen new "Perspective" chapters feature expert commentary and alternative viewpoints on the most clinically relevant topics Added chapters on gastrointestinal bleeding, abdominal trauma, and abdominal vascular emergencies--along with minimally invasive surgery chapters woven throughout the text--present current, ready-to-use insights designed to enhance surgical care and recovery More than 1,250 illustrations (most in full color)
This comprehensive text presents a critical discussion of the scopes and limitations of various organic synthetic methodologies that are available for performing asymmetric transformations. In addition to purely chemical methods, the book covers applications of new enzymes and other biological systems that are increasingly useful in asymmetric methodology.
The fields of molecular evolution, genome evolution, and evolutionary genetics are now well-established. Remarkably, however, although all evolutionary modifications begin at the cellular level, and despite the advances made in cell biology and microbiology over the past few decades, there is as yet no recognised discipline of evolutionary cell biology. The goal of this book is to help establish the foundations for this emerging field. Its principal aims are twofold: firstly, to promote an understanding among evolutionary biologists as to why the cellular details matter if we are to understand the mechanisms of evolution; secondly, to make clear to non-evolutionary biologists - cell biologists in particular - that evolution is not just a matter of natural selection and optimization, but a process whose reach depends on other population genetic features such as mutation, recombination, and random genetic drift. Although there are many excellent books on cell biology, microbiology, and biophysics, almost no attention is given to evolution. Likewise, although there are numerous evolutionary biology books on the market, none of them gives more than passing attention to details at the cellular level. Thus Evolutionary Cell Biology is genuinely novel, offering a broader understanding of evolutionary processes and an appreciation for the many interesting problems that remain to be solved at the cellular and subcellular levels. This advanced textbook is aimed at both cell biologists and evolutionary biologists. It will be accessible to upper-level undergraduates in biology, and certainly to graduate students in all areas of the life sciences. Professionals from a wide range of fields - cell biology, microbiology, evolution, biophysics, biochemistry, and mathematics - will be exposed to entirely new ideas not traditionally covered in their primary fields of expertise.
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