This book describes a novel and unique approach to the treatment of human diseases based on the study of natural animal models. A natural animal model is defined as an animal group or species that possesses a set of biochemical/physiological characteristics which are natural and adaptive for that animal, but are quite abnormal for humans. For example, how is it that birds can tolerate blood glucose concentrations which in humans are associated with diabetes. The natural animal model is living proof that a biological answer to this question is available. By studying natural animal models, we can gain valuable insights into the treatment of various human clinical disorders. Covering a wide range of disorders, this book describes in detail how medical scientists can take advantage of all the “research” that nature has already performed over billions of years in biological problem solving through extensive animal design testing and selection./a
This comprehensive text presents a critical discussion of the scopes and limitations of various organic synthetic methodologies that are available for performing asymmetric transformations. In addition to purely chemical methods, the book covers applications of new enzymes and other biological systems that are increasingly useful in asymmetric methodology.
Concise, portable, and user-friendly, The Washington ManualTM Infectious Diseases Subspecialty Consult, Third Edition, provides essential information needed to evaluate patients on a subspecialty consult service. This edition offers state-of-the-art content on the diagnosis, investigation, and treatment of a wide variety of infectious diseases, including coverage of new and emerging pathogens, rapid molecular diagnostics for infectious diseases, and new therapeutic and preventive strategies. Ideal for trainees and practicing physicians who need quick access to current scientific and clinical information in this rapidly changing area, the manual is also useful as a first-line resource for internists and other primary care providers.
A new selection of letters, statements, and interviews reveals the preoccupations, thoughts, and ideas of Francis Bacon, one of the twentieth century’s most influential and important artists. The documents selected for Francis Bacon: A Self-Portrait in Words illustrate Bacon’s sharp wit and ability to express complex ideas in highly personal, memorable language. Included here are not only letters to friends, patrons, and fellow artists, but also intriguing notes and lists of paintings. They often come with a sketch as an aide-mémoire or an injunction to himself as he worked in the studio, and many have only come to light since his death. Bacon's letters mirror and reveal his dominant preoccupations at different points throughout his long career. Most of Bacon's letters have never been published and include several that he wrote to author Michael Peppiatt. Particularly intriguing is the record of a dream that he jotted down, outlining impossibly beautiful paintings he had conjured up in his sleep. Together with photographs, archive material, and works by the artist are numerous reproductions of Bacon's characteristic handwriting, from the briefest jottings and notes to more extensive letters and statements. Bacon frequently came up with memorable epithets and definitions. He delighted in doing with words what he set out to do in painting: "I like phrases that cut me." Peppiatt explores the personal legacy of one of the twentieth century's most important painters and presents a compelling verbal self-portrait that reveals both man and artist.
The Plot Against the Peace, which was first published in 1945, uncovers Nazi Germany’s secret plans for a Third World War. The book reveals how the behind-the-scenes clique which really rules Germany is plotting to undermine the peace, split the United Nations, and convert military defeat into actual victory. Written by two journalists who have won an international reputation for their exposés of fifth-column activities and worldwide fascist intrigues, this book offers thoroughly documented, indisputable evidence to prove that Germany’s undercover apparatus is at work in the United States today, laying the groundwork for a post-war secret offensive against America. The book disclosed how German spies and assassins are already carrying out their new assignments in the United States, as throughout the rest of the world. The Plot Against the Peace is a book that names names. Among the vitally important disclosures discussed are how Germany is secretly preparing for the continued post-war operations of the Nazi apparatus; the real story behind the German factories of death; the clandestine building of German hidden arsenals in Spain, Argentina and other countries; the plot for maintaining a Nazi-Junker officer corps in temporary exile abroad after the war; who are the “real brains” behind the German international network; how the Germans have smuggled funds, diamonds and other valuables into the United States to finance their post-war machinations; and what the German plans are for disuniting the United Nations, inciting international turmoil and thus making impossible the fulfilment of the Allied peace aims. The authors have left nothing to the imagination in their account of the hitherto untold secret history of Nazism, and in their description of the character and deeds of the German General Staff. But, as the authors write, “Those facts had to be recorded and they have to be read.” An amazing, revealing and urgent document.
During the seventeenth and eighteenth centuries the expanding Russian empire was embroiled in a dramatic confrontation with the nomadic people known as the Kalmyks who had moved westward from Inner Asia onto the vast Caspian and Volga steppes. Drawing on an unparalleled body of Russian and Turkish sources—including chronicles, epics, travelogues, and previously unstudied Ottoman archival materials—Michael Khodarkovsky offers a fresh interpretation of this long and destructive conflict, which ended with the unruly frontier becoming another province of the Russian empire.Khodarkovsky first sketches a cultural anthropology of the Kalmyk tribes, focusing on the assumptions they brought to the interactions with one another and with the sedentary cultures they encountered. In light of this portrait of Kalmyk culture and internal politics, Khodarkovsky rereads from the Kalmyk point of view the Russian history of disputes between the two peoples. Whenever possible, he compares Ottoman accounts of these events with the Russian sources on which earlier interpretations have been based. Khodarkovsky's analysis deepens our understanding of the history of Russian expansion and establishes a new paradigm for future study of the interaction between the Russians and the non-Russian peoples of Central Asia and Transcaucasia.
This book synthesizes new information about the environmental advantages of plant resistance, transgenic resistance, the molecular bases of resistance, and the use of molecular markers to map resistance genes. Readers are presented in-depth descriptions of techniques to quantify resistance, factors affecting resistance expression, and the deployment of resistance genes. New information about gene-for-gene interactions between resistant plants and arthropod biotypes is discussed along with the recent examples of using arthropod resistant plants in integrated pest management systems.
The best way to learn about Romantic poetry is to plunge in and read a few Romantic poems. This book guides the new reader through this experience, focusing on canonical authors - Wordsworth, Coleridge, Byron, Keats, Blake and Shelley - whilst also including less familiar figures as well. Each chapter explains the history and development of a genre or sets out an important context for the poetry, with a wealth of practical examples. Michael Ferber emphasizes connections between poets as they responded to each other and to great literary, social and historical changes around them. A unique appendix resolves most difficulties new readers of works from this period might face: unfamiliar words, unusual word order, the subjunctive mood and meter. This enjoyable and stimulating book is an ideal introduction to some of the most powerful and pleasing poems in the English language, written in one of the greatest periods in English poetry.
One of the most colorful characters in the Napoleonic pantheon, Gebhard Leberecht von Blücher (1742–1819) is best known as the Prussian general who, along with the Duke of Wellington, defeated Napoleon at the Battle of Waterloo. Throughout his long career, Blücher distinguished himself as a bold commander, but his actions at times appeared erratic and reckless. This magnificent biography by Michael V. Leggiere, an award-winning historian of the Napoleonic Wars, is the first scholarly book in English to explore Blücher’s life and military career—and his impact on Napoleon. Drawing on exhaustive research in European archives, Leggiere eschews the melodrama of earlier biographies and offers instead a richly nuanced portrait of a talented leader who, contrary to popular perception, had a strong grasp of military strategy. Nicknamed “Marshal Forward” by his soldiers, he in fact retreated more often than he attacked. Focusing on the campaigns of 1813, 1814, and 1815, Leggiere evaluates the full effects of Blücher’s operations on his archenemy. In addition to providing military analysis, Leggiere draws extensively from Blücher’s own writings to reveal the man behind the legend. Though tough as nails on the outside, Blücher was a loving family man who deplored the casualties of war. This meticulously written biography, enhanced by detailed maps and other illustrations, fills a large gap in our understanding of a complex man who, for all his flaws and eccentricities, is justly credited with releasing Europe from the yoke of Napoleon’s tyranny.
Main headings: I. Basic concepts of pulsatile arterial hemodynamics. - II. Pathophysiological mechanisms. - III. Arterial stiffness, wave reflections, cardiovascular risk and end-organ damage. - IV. Clinical aspects of arterial stiffness and wave reflections. - V. Therapeutic aspects of arterial stiffness and wave reflections.
Pierre Bourdieu is regarded as one of the foremost social philosophers of the twentieth century. His output included extensive studies of education, culture, art and language. He went beyond being a sociologist to being regarded in the same 'public intellectual' role as Sartre, de Beauvoir and Foucault. Issues surrounding language permeate Bourdieu's entire oeuvre. Although he did undertake empirical studies on language in a range of contexts, very little of this was published. This book redresses this balance; it sets out what Bourdieu has to say about language and why, and exemplifies this approach through a series of empirical language studies. This book will appeal to researchers across the world in fields such as sociology, philosophy, cultural studies, anthropology but is of especial interest to language and linguistics scholars.
This book examines our current understanding of the population dynamics of one kind of interaction - that between insect parasitoids and their hosts. Parasitoids are amongst the most abundant of all animals, and make up about 10% or more of metazoan species. Almost no insect species escape their attack. Host-parasitoid interactions were first modelled over fifty years ago, but for many years there was little good empirical information on the important factors that affect host and parasitoid populations. The models were very simple, and their predictions rather divorced from the complexity of what was visible in the field. Now, better data is available on many components of host-parasitoid systems, from field observations and laboratory and field experiments, and this allows a much closer correspondence between models and data. In particular, the past twenty years have seen major advances in our understanding of how host-parasitoid interactions are influenced by spatial processes, by age-structure effects, and by competition from additional host and parasitoid species. The result is a body of theory that makes direct contact with real systems in the field, and provides us with a detailed understanding of what underpins a whole area of population dynamics. In this book, Michael P Hassell pulls the theory and field data together to present an elegant illustration of the way in which ecological studies advance.
Founded by Robert M. Savini in 1933, Astor Pictures Corporation distributed hundreds of films in its 32 years of operation. The company distributed over 150 first run features in addition to the numerous re-releases for which it became famous. Astor had great success in the fields of horror and western movies and was a pioneer in African-American film productions. While under Savini's management, Astor and its subsidiaries were highly successful, but after his death in 1956 the company was sold, leading to eventual bankruptcy and closure. This volume provides the first in-depth look at Astor Pictures Corporation with thorough coverage of its releases, including diverse titles like La Dolce Vita and Frankenstein's Daughter.
Clinical Chemistry: Principles, Techniques, and Correlations, Enhanced Eighth Edition demonstrates the how, what, why, and when of clinical testing and testing correlations to help you develop the interpretive and analytic skills you’ll need in your future career.
The Spanish Civil War was fought on land and at sea but also in an age of great interest in air warfare and the rapid development of warplanes. The war in Spain came a turning point in the development of military aircraft and was the arena in which new techniques of air war were rehearsed including high-speed dogfights, attacks on ships, bombing of civilian areas and tactical air-ground cooperation. At the heart of the air war were the Condor Legion, a unit composed of military personnel from Hitler's Germany who fought for Franco's Nationalists in Spain. In this book, Michael Alpert provides the first study in English of the Spanish Civil War in the air. He describes and analyses the intervention of German, Italian and Soviet aircraft in the Spanish conflict, as well as the supply of aircraft in general and the role of volunteer and mercenary airmen. His book provides new perspectives on the air war in Spain, the precedents set for World War II and the possible lessons learnt.
Creating a 3D Animated CGI Short presents an insightful behind-the-scenes tour of the entire production process for 3D artists, animators, and independent filmmakers who are interested in creating their own CGI shorts as well as for those who are simply fans and enthusiasts of CGI films in general. This book presents detailed examples of every step of the production process; from initial concept through character design, set design, modeling, texturing, lighting, camera animation, character animation, lip sync, rendering, post-production, compositing, and all the way to film festival submissions and online web distribution. It truly has something for everyone interested in CGI films. Using readily available off-the-shelf hardware and software such as modo, LightWave 3D, FPrime, HD Instance, Peak, Shake, iMovie, iDVD, GarageBand and more, Creating a 3D Animated CGI Short shows how to produce a complete 3D animated CGI Short, including how to fund the production by taking on paid freelance projects along the way. Where other filmmaking books typically describe industry standard methodologies that are most effective for larger productions, this book shows how to drastically simplify and condense those processes and focus only on the essential elements that will enable a single artist or filmmaker to complete a CGI short on their own.
Covering genres from adventure and fantasy to horror, science fiction, and superheroes, this guide maps the vast terrain of graphic novels, describing and organizing titles to help librarians balance their graphic novel collections and direct patrons to read-alikes. New subgenres, new authors, new artists, and new titles appear daily in the comic book and manga world, joining thousands of existing titles—some of which are very popular and well-known to the enthusiastic readers of books in this genre. How do you determine which graphic novels to purchase, and which to recommend to teen and adult readers? This updated guide is intended to help you start, update, or maintain a graphic novel collection and advise readers about the genre. Containing mostly new information as compared to the previous edition, the book covers iconic super-hero comics and other classic and contemporary crime fighter-based comics; action and adventure comics, including prehistoric, heroic, explorer, and Far East adventure as well as Western adventure; science fiction titles that encompass space opera/fantasy, aliens, post-apocalyptic themes, and comics with storylines revolving around computers, robots, and artificial intelligence. There are also chapters dedicated to fantasy titles; horror titles, such as comics about vampires, werewolves, monsters, ghosts, and the occult; crime and mystery titles regarding detectives, police officers, junior sleuths, and true crime; comics on contemporary life, covering romance, coming-of-age stories, sports, and social and political issues; humorous titles; and various nonfiction graphic novels.
One of the first men to reach the North Pole, Henson was all but ignored in favor of partner Admiral Robert Peary. But today his contributions are widely recognized and his place in history is secure. This is the amazing story of his life.
Alexander Pushkin’s lyric poetry—much of it known to Russians by heart—is the cornerstone of the Russian literary tradition, yet until now there has been no detailed commentary of it in any language. Michael Wachtel’s book, designed for those who can read Russian comfortably but not natively, provides the historical, biographical, and cultural context needed to appreciate the work of Russia’s greatest poet. Each entry begins with a concise summary highlighting the key information about the poem’s origin, subtexts, and poetic form (meter, stanzaic structure, and rhyme scheme). In line-by-line fashion, Wachtel then elucidates aspects most likely to challenge non-native readers: archaic language, colloquialisms, and unusual diction or syntax. Where relevant, he addresses political, religious, and folkloric issues. Pushkin’s verse has attracted generations of brilliant interpreters. The purpose of this commentary is not to offer a new interpretation, but to give sufficient linguistic and cultural contextualization to make informed interpretation possible.
Did you know the Nintendo Wii had a medical condition named after it? Or that the Sega Saturn almost had the Nintendo 64's graphics chip? Did you realize the Atari Jaguar contained five different processors? Are you aware that a fake website about beekeeping was used to promote an Xbox game? Learn about all of this and more in this unique trivia book about the history of video game consoles that gives you the complete stories in detail! These facts cover a wide range of subjects, such as which console introduced certain technology and features, esoteric hardware oddities, marketing fails and successes, stories behind key games, how certain indispensable people shaped the whole industry, development history, court cases, peculiar events, weird relationships between companies and technical explanations. Plenty of these would be obscure facts that you may not know, but even if you are familiar with them, do you know the full story? 31 video game consoles stretching from 1972 to 2017 are covered, containing more than 235 in-depth facts, numerous other pieces of trivia and over 350 images to create a single package unlike any other that gamers of all ages will find interesting! If you want to fill your head with plenty of knowledge about your favorite video game consoles to amaze your friends with, then this book is for you!
(Vocal Piano). 11 songs from Buble's 10th studio album released in 2018 are presented in this vocal collection with piano accompaniment. Songs include: Forever Now * Help Me Make It Through the Night * I Only Have Eyes for You * La Vie En Rose (Take Me to Your Heart Again) * Love You Anymore * My Funny Valentine * Such a Night * Unforgettable * When I Fall in Love * When You're Smiling (The Whole World Smiles with You) * Where or When.
Paperback edition of the Winner of three 2005 Catholic Press Association Books Awards! Design and Production First Place. As the Mother of God, Mary surpasses all other humans and yet is united with all who are to be saved. Here you will find a magnificent and inspiring collection of colorful images, meditations, and prayers about and for Mary, both painted and written.Many of McGraths paintings in this collection are the result of his loving fascination with Black Madonnas, which have inspired pilgrims, saints, and sin-sick souls for centuries. Combined with Richard Fragomenis poetic and candid prayers, these images of Mary speak directly to all people who struggle to find meaning and joy in a world filled with crisis, divisiveness, and insecurity. They speak, too, to the artistic, creative soul in all of us, which longs to see things in new and challenging ways while holding on to the history and traditions of our Catholic heritage.
This text is a timely and wide-ranging study providing essential background to the development of global modernity through the European encounter with China. Considering differing notions of peace, empire, trade, religion, and diplomacy as touchstones in the relations between China and Europe on mutuality, the book examines five encounters with France, Portugal, Holland, the pope, and Russia between 1248 and 1720, and reflects on concepts that the West took for granted but which did not successfully cross over into the Chinese world. This cutting edge text provides key insights into the cultural and political conflict which lay at the heart of early Chinese-European relations, as the West's understanding of the truth and appropriateness of its cultural norms was confronted by China's norms and beliefs.
Dublin 1940. An IRA attack leaves two guards dead on the streets of Dublin. Two days later, a battle between warring gangs erupts at a race meeting, and on Ireland's east coast the cremated bodies of a wealthy family of five are found in their shuttered, burned-out villa. Dispatched from Special Branch to investigate, Detective Inspector Stefan Gillespie soon finds himself caught in a web of Irish, British and German Intelligence - all playing against each other, all watching each other, and all plagued by rogue operators they can't quite control, as the certainty grows that Hitler is about to invade England. And then, Stephen is sent to Berlin on a sensitive mission. His journey home becomes a dangerous pursuit in which no one can be trusted and the information he carries puts his life on the line.
2008 Catholic Press Association Award Winner! This magnificent new publication distinguishes itself from others by its comprehensiveness, and in its coverage of Eastern, as well as Western, saints. The book contains approximately 7,000 Saints and Blesseds. Entries are placed in alphabetical order according to name. Where there are numerous saints with the same name (for example John) these are now listed chronologically. The entries include date and place of birth and death as well as family background, education, activity for which the saint is remembered, and whether he/she is a patron saint. In order to be comprehensive, even possibly mythical saints are included 'Barbara, Christopher and Katherine of Alexandria, because their stories have been so important in art, literature and popular devotion. This is the most complete and accurate Dictionary of Saints available.
No. 1 bestseller and superstar doing what he does best, introducing millions of avid readers to little-known peoples and places. Until the early 1990s, when the Berlin Wall came tumbling down, travelling behind the iron curtain was never easy. In undertaking his new journey through Eastern Europe, breathing in its rich history, and exquisite sights and talking to its diverse peoples, Michael fills what has been a void in his own experience and that of very many others. NEW EUROPE is very much a voyage of discovery, from the snows of the Julian Alps to the beauty of the Baltic sea, he finds himself in countries he'd barely heard of, many unfamiliar and mysterious, all with tragic histories and much brighter futures. During his 20-country adventure Palin meets Romanian lumberjacks, drives the 8.58 stopping train from Poznan to Wolsztyn, treads the catwalk at a Budapest fashion show, learns about mine-clearing in Bosnia and watches Turkish gents wrestling in olive oil. As with all his bestselling books, in his uniquely entertaining style, Palin opens up a new and undiscovered world to millions of readers.
In this uproarious memoir and meticulously researched cultural journey, writer Michael Moran keeps company with a gallery of fantastic characters. In chronicling the resurrection of the nation from war and the Holocaust, he paints a portrait of the unknown Poland, one of monumental castles, primeval forests and, of course, the Poles themselves. This captivating journey into the heart of a country is a timely and brilliant celebration of a valiant and richly cultured people.
The Rocket Lab: Maurice Zucrow, Purdue University, and America’s Race to Space focuses on the golden era of space exploration between 1946 and 1966, specifically the life and times of Purdue University’s Dr. Maurice J. Zucrow, a pioneering teacher and researcher in aerospace engineering. Zucrow taught America’s first university course in jet and rocket propulsion, wrote the field’s first textbook, and established the country’s first educational Rocket Lab. He was part of a small circle of innovators who transformed Purdue into the country’s largest engineering university, which became a cradle of astronauts. Taking a chronological and thematic approach, The Rocket Lab weaves between the local and national, drawing in rival universities, especially Harvard, MIT, Princeton, and Caltech. Also covered is Zucrow’s role in the national project system of research and development through World War II and the Cold War. At Aerojet, he was one of the country’s original project engineers, dedicated to scientific-technical expertise and the stepwise approach. He made vanguard power plant contributions to the Northrop Flying Wing, as well as the Corporal, Nike, and Atlas missiles, among others. Zucrow’s work in propulsion helped to improve the country’s arsenal of ballistic missiles and space launchers, and as a teacher, he educated the first generation of aerospace engineers. This book elevates Zucrow and the central role he played in getting the United States to space.
In the end, we must acknowledge that we have been held spellbound by a master storyteller. Highly recommended."--Library Journal Starred Review "A truly fine novel. It's filled with exactitude of place and people, taking us into a world that seethes with dangerous secrets. On that treacherous journey, Michael Genelin makes unfamiliar worlds seem knowable, and does so with great style."--Pete Hamill, author of North River "A terrific novel by a man who knows crime, knows Europe, and knows how to write. Siren of the Waters is a genuine pleasure."--Thomas Perry, author of Silence Jana Matinova entered the Czechoslovak police force as a young woman, married an actor, and became a mother. The regime destroyed her husband, their love for one another, and her daughter's respect for her. But she has never stopped being a seeker of justice. Now, as a commander in the Slovak police force, she liaises with colleagues across Europe as they track the mastermind of an international criminal operation involved in, among other crimes, human trafficking. Her investigation takes her from Ukraine to Strasbourg, from Vienna to Nice, in a hunt for a ruthless killer and the beautiful young Russian woman he is determined either to capture or destroy. Michael Genelin, a graduate of UCLA and the UCLA Law School, has served in the LA District Attorney's Office and the US Department of Justice in Central Europe. He has written for film and has been an adviser to television series. He now lives with his wife and daughter in Paris.
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