“A detailed and engaging account of the development of the superconducting supercollider, one of the largest scientific undertakings in the United States.” —Journal of American History Starting in the 1950s, US physicists dominated the search for elementary particles; aided by the association of this research with national security, they held this position for decades. In an effort to maintain their hegemony and track down the elusive Higgs boson, they convinced President Reagan and Congress to support construction of the multibillion-dollar Superconducting Super Collider project in Texas—the largest basic-science project ever attempted. But after the Cold War ended and the estimated SSC cost surpassed ten billion dollars, Congress terminated the project in October 1993. Drawing on extensive archival research, contemporaneous press accounts, and over one hundred interviews with scientists, engineers, government officials, and others involved, Tunnel Visions tells the riveting story of the aborted SSC project. The authors examine the complex, interrelated causes for its demise, including problems of large-project management, continuing cost overruns, and lack of foreign contributions. In doing so, they ask whether Big Science has become too large and expensive, including whether academic scientists and their government overseers can effectively manage such an enormous undertaking. “Focusing on the scientific, technical, and political conflicts that led to delays, ever rising costs, and eventually the SSC’s cancelation by Congress, Tunnel Visions is a true techno-thriller.” —Burton Richter, winner of the Nobel Prize in Physics “Most good science stories are tales of discovery and success, but failure can be just as riveting. Here two historians and an archivist describe the greatest particle physics experiment that never was.” —Scientific American
The structure space of a closed topological -manifold classifies bundles whose fibers are closed -manifolds equipped with a homotopy equivalence to . The authors construct a highly connected map from to a concoction of algebraic -theory and algebraic -theory spaces associated with . The construction refines the well-known surgery theoretic analysis of the block structure space of in terms of -theory.
The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.
A wealth of new experimental and theoretical results has been obtained in solar physics since the first edition of this textbook appeared in 1989. Thus all nine chapters have been thoroughly revised, and about 100 pages and many new illustrations have been added to the text. The additions include element diffusion in the solar interior, the recent neutrino experiments, methods of image restoration, observational devices used for spectroscopy and polarimetry, and new developments in helioseismology and numerical simulation. The book takes particular advantage of the results of several recent space missions, which lead to substantial progress in our understanding of the Sun, from the deep interior to the corona and solar wind.
“I welcome this book because it reminds therapists to engage deeply in reflexive interrogation of clinical privilege, and to centre the narratives and wisdom of the trans and non-binary people we serve.” Matthew Mills (he, him), President of the British Association of Gender Identity Specialists, Lead Consultant Speech and Language Therapist “This book is compulsory reading for anyone, personally and/or professionally, seeking to support trans and non-binary individuals and community groups.” Dr Paul Simpson (he, him), Lecturer in Sociology, University of Manchester, UK and extensively published in gender and sexuality in later life. "This book is a welcome and much needed resource on Gender Affirmative Therapy to guide therapists and practitioners to ensure best clinical practices when working with gender.” Christiane Sanderson, Independent Counsellor, Author and Educator, London, UK Increasing numbers of people openly identify as transgender and non-binary and questions of gender identity and diversity are coming up more frequently in psychological therapy. Gender Affirming Therapy takes you on a journey to discover the inner lives and challenges of gender-diverse people, seeking to spark compassion and build confidence in working with these communities. Assuming no prior knowledge and accessibly written, this book aims to bridge the gap to ensure that more mental health professionals are better prepared to support gender-diverse clients in a way that is effective, ethical and affirmative. Key features of this book include: • ‘In their Own Words’ sections containing interviews directly from transgender and non-binary individuals • Key point summary and reflection boxes • Coverage of new advancements in the field Drawing on research and clinical experience, Gender Affirming Therapy has been devised as an open conversation between colleagues which centres transgender and non-binary individuals as the experts and at the very heart of the book. Laura Scarrone Bonhomme (she/her), is a Consultant Clinical Psychologist who specialises in Gender, Sexual, and Relationship Diversity. She provides assessment, psychotherapy, and training to other professionals through www.affirm.lgbt. Skye Davies (she/they) is a Peer Support Worker at TransPlus, a gender dysphoria service. They also work as a Volunteer Counsellor at Metro, helping LGBTQ+ people. Dr Michael Beattie (he/him) is a Counselling Psychologist in private practice with research interests in the psychology of men and masculinities. In addition to psychotherapy, Michael provides training in Gender, Sexual, and Relationship Diversity through www.affirm.lgbt.
Consistently lauded for its comprehensiveness and full-color color presentation, the latest edition of Rheumatology by Marc C. Hochberg, MD, MPH et al. continues the tradition of excellence of previous editions. Designed to meet the needs of the practicing clinician, it provides extensive, authoritative coverage of rheumatic disease from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format covering all major disorders of the musculoskeletal system in complete, self-contained chapters. Get trusted perspectives and insights from chapters co-authored by internationally renowned leaders in the field, 25% of whom are new to this edition. Track disease progression and treat patients more effectively with the most current information, including 22 new chapters on genetic findings, imaging outcomes, and cell and biologic therapies as well as rheumatoid arthritis and SLE. Incorporate the latest findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics.
Now more than ever health care professionals play an increased role in the promotion of health to populations. Unique and innovative, Interprofessional Perspectives for Community Practice: Promoting Health, Well-being and Quality of Life weaves everyday care into prevention, community, and population health, creating a new and more expansive vision of health for all without compromising traditional practices. Authors and editors Drs. Pizzi and Amir discuss and illustrate a client-centered preventive and health, well-being and quality of life approach rooted in best practice principles from interprofessional literature and firsthand experience. The text illustrates how allied health professionals implement those principles in their everyday and traditional practices with an emphasis on exploring health and well-being issues. Interprofessional Perspectives for Community Practice provides detailed guidance in program development and implementation. What’s included in Interprofessional Perspectives for Community: Clinical anecdotes on successful community practices A focus on primary and secondary prevention Assessments, interventions, and community practice examples Descriptions of community-based practice settings such as adult day care, independent living programs, hospice, and home health care Health and wellness across the lifespan Bonus chapters available online as PDFs for readers The first text of its kind to weave interprofessionalism, community practice, and health, well-being, and quality of life, Interprofessional Perspectives for Community Practice: Promoting Health, Well-being and Quality of Life is for all health care workers and students who wish to transfer practice skills from the clinical setting to a population-based program development model.
Blending the latest technical and clinical skills of hand surgery and hand therapy, Hand and Upper Extremity Rehabilitation: A Practical Guide, 4th Edition walks you through the treatment of common medical conditions affecting the upper extremities and highlights non-surgical and surgical procedures for these conditions. This expanded fourth edition presents the latest research in hand and upper extremity rehabilitation and provides the purpose and rationale for treatment options. - Clinical outcomes included in each chapter relate clinical expectations to the results of clinical research trials, providing you with the expected range of motion and function based on evidence in the literature. - Highly structured organization makes information easy to find, allowing the text to function as a quick reference in the clinical setting. - Contributors from a variety of clinical settings like hand therapy clinics, hospitals, and outpatient clinics means you get to learn from the experience of clinicians working in diverse clinical contexts like yourself. - Over 400 line drawings and clinical photographs delineate important concepts described in text. - Chapters divided into eight parts - Wound Management, Nerve Injuries, Tendon Injuries, Shoulder, Elbow, Wrist and Distal Radial Ulnar Joint, Hand, and Special Topics - so information can be located quickly. - 51 leading experts offer fresh insight and authoritative guidance on therapeutic approaches for many common diagnoses. - Treatment guidelines presented for each stage of recovery from a wide range of upper extremity conditions. - NEW! Authoritative quick reference guide to surgical and non-surgical procedures for hand and all upper extremity conditions. - NEW! Updated information and references offers the latest information and research in the areas of hand and upper extremity rehabilitation. - NEW! Larger trim size and new design accommodates a two-column format that is easier to follow.
Driven by declining profits and government regulation, a new form of class-wide business leadership has emerged: a transcorporate network that is giving a new coherence and power to business in both America and Britain. This book delineates the "inner circle" of top executives who play a leading role in this network, advising the highest levels of government and working to promote a political environment favorable to all business.
This volume provides valuable summaries on many aspects of advanced semiconductor heterostructures and highlights the great variety of semiconductor heterostructures that has emerged since their original conception. As exemplified by the chapters in this book, recent progress on advanced semiconductor heterostructures spans a truly remarkable range of scientific fields with an associated diversity of applications. Some of these applications will undoubtedly revolutionize critically important facets of modern technology. At the heart of these advances is the ability to design and control the properties of semiconductor devices on the nanoscale. As an example, the intersubband lasers discussed in this book have a broad range of previously unobtainable characteristics and associated applications as a result of the nanoscale dimensional control of the underlying semiconductor heterostructures. As this book illustrates, an astounding variety of heterostructures can be fabricated with current technology; the potentially widespread use of layered quantum dots fabricated with nanoscale precision in biological applications opens up exciting advances in medicine. In addition, many more excellent examples of the remarkable impact being made through the use of semiconductor heterostructures are given. The summaries in this volume provide timely insights into what we know now about selected areas of advanced semiconductor heterostructures and also provide foundations for further developments.
Although mechanisms involved in the spread of cancer have been the subject of a major research endeavor over the past decade, metastatic tumors still account for significant clinical morbidity and the failure of cancer treatment. Not only are the vascular pathways the most common route for the dissemination of cancer cells, but interactions between the cells and the circulation act as important rate-regulators for the metastatic process. This authoritative, multi-authored volume addresses the importance of microcirculation in cancer metastasis. The book begins with up-to-date reviews on the biology of endothelial cells and the structure and physiology of the normal and tumor microcirculations, and then emphasizes interactions between components of the microcirculation and cancer cells. Metastasis is discussed through chapters exploring the entry of cancer cells into the circulation, the biophysics and morphology of cancer cell traffic and arrest, interactions with host cells and the basement membranes, and angiogenesis. This fascinating book will interest oncologists, pathologists, and students of metastasis or the microcirculation.
Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. - Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle - Actual data figures from original sources illustrating key concepts and findings - Introduction to basic neuropharmacology terms and concepts - Introduction to numerous animal models used to study diverse aspects of drug use. - Thorough review of extant work on the neurobiology of addiction
The new edition of this popular text presents microbiology in a succinct, easy-to-use, and engaging manner. Clear discussions explain how microbes cause disease in humans, and review the updated vaccines and new antibiotics currently available to treat these diseases. Expert coverage of basic principles, the immune response, laboratory diagnosis, bacteriology, virology, mycology, and parasitology ensures that you’ll understand all the facts vital to the practice of medicine today. A revised artwork program illustrates the appearance of disease, simplifying complex information, while text boxes and additional summary tables emphasize essential concepts and learning issues for more efficient exam review. Online access to Student Consult-where you’ll find the complete contents of the book, fully searchable...Integration Links to bonus content in other Student Consult titles...updated features for both students and instructors...and much more-further enhances your study and exponentially boosts your reference power. Focuses on why the biologic properties of organisms are important to disease in humans, equipping you with a practical understanding of microbiology. Examines etiology, epidemiology, host defenses, identification, diagnosis, prevention, and control for each microbe in consistently organized chapters, enabling you to find the information you need fast. Features summary tables and text boxes that emphasize essential concepts and learning issues, enabling you to make your exam review more efficient. Correlates basic science with clinical practice through review questions at the end of each chapter to help you understand the clinical relevance of the organisms examined. Uses clinical cases from literature reports to illustrate the epidemiology, diagnosis, and treatment of infectious diseases. Features revised artwork-more than 635 brilliant images, nearly all in full color-that offers a more consistent and modern approach to the study of medical microbiology. Provides more clinical photographs throughout that help you better understand the clinical applications of microbiology. Offers expanded use of summary boxes for bacteria throughout all organism chapters to further enhance your review and learning. Includes enhanced Student Consult features including self-assessment questions, clinical cases, animations showing the actions of various important toxins, and a PowerPoint presentation with supplemental images of organisms and stains.
Drawing on scientific evidence from medicine, psychology, criminology, and sociology, this book explores the veracity of claims about marijuana use and misuse. Is marijuana an innocent recreational pleasure and medicinal boon or an evil that must be outlawed to protect the American public? With the legal and social status of marijuana in transition, accurate and objective information regarding its use is necessary for informed decisionmaking in both the personal and political arenas. To distinguish truth from fiction, this book draws on scientific evidence from medicine, psychology, criminology, and sociology, exploring many of the most commonly held beliefs about marijuana and documenting the scope and impact of its use-and abuse-in the United States. The work is organized around five broad topics: patterns and trends; risks and benefits; causes and consequences; criminalization; and practice and policy. It opens with examinations of use and abuse trends among various U.S. subpopulations, then goes on to scrutinize claims about the medical risks associated with the substance. Social and interpersonal causes and consequences of marijuana use are addressed, as is the history and future of marijuana legislation in the United States. Readers will come away from this book with broad-based knowledge about marijuana-and a scientifically grounded understanding of the benefits and risks of marijuana use.
For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Endocrine Secrets, 7th Edition, features the Secrets' popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style – making inquiry, reference, and review quick, easy, and enjoyable. - The proven Secrets Series® format gives you the most return for your time – succinct, easy to read, engaging, and highly effective. - Fully revised and updated throughout, including protocols and guidelines that are continuously evolving and that increasingly dictate best practices. - Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams. - Features bulleted lists, mnemonics, practical tips from prominent endocrinologists – all providing a concise overview of important board-relevant content. - Keeps you up to date with new techniques and technologies, as well as changing treatment options and drug information. - Equips you for effective practice with coverage of the most current developments in obesity management, weight loss drugs, and bariatric surgery; type 2 diabetes mellitus; insulin therapy; thyroid cancer; osteoporosis therapies; and much more. - Portable size makes it easy to carry with you for quick reference or review anywhere, anytime.
“There is a continuing demand for up to date organic & bio-organic chemistry undergraduate textbooks. This well planned text builds upon a successful existing work and adds content relevant to biomolecules and biological activity”. -Professor Philip Page, Emeritus Professor, School of Chemistry University of East Anglia, UK “Introduces the key concepts of organic chemistry in a succinct and clear way”. -Andre Cobb, KCL, UK Reactions in biochemistry can be explained by an understanding of fundamental organic chemistry principles and reactions. This paradigm is extended to biochemical principles and to myriad biomolecules. Biochemistry: An Organic Chemistry Approach provides a framework for understanding various topics of biochemistry, including the chemical behavior of biomolecules, enzyme activity, and more. It goes beyond mere memorization. Using several techniques to develop a relational understanding, including homework, this text helps students fully grasp and better correlate the essential organic chemistry concepts with those concepts at the root of biochemistry. The goal is to better understand the fundamental principles of biochemistry. Features: Presents a review chapter of fundamental organic chemistry principles and reactions. Presents and explains the fundamental principles of biochemistry using principles and common reactions of organic chemistry. Discusses enzymes, proteins, fatty acids, lipids, vitamins, hormones, nucleic acids and other biomolecules by comparing and contrasting them with the organic chemistry reactions that constitute the foundation of these classes of biomolecules. Discusses the organic synthesis and reactions of amino acids, carbohydrates, nucleic acids and other biomolecules.
Printing Terror places horror comics of the Cold War in dialogue with the anxieties of their age. It rejects the narrative of horror comics as inherently, and necessarily, subversive and explores, instead, the ways in which these texts manifest white male fears over America’s changing sociological landscape. It examines two eras: the pre-CCA period of the 1940s up to 1954, and the post-CCA era to 1975. The book examines each of these periods through the lenses of war, gender, and race, demonstrating that horror comics at this time were centered on white male victimhood and the monstrosity of the gendered and/or racialised other. It is of interest to scholars of horror, comics studies, and American history.
This book considers governance and policy-making within the maritime sector, and focuses significantly on the dimensional context within which governance works. Recognising the importance of understanding governance and policy at times when the world is faced with social, political, and economic problems, it highlights the fact that both areas are equally significant in understanding today’s political economy. By focusing on the maritime sector, a pillar industry supporting international trade activities, the book offers a unique perspective to explain the difficulties of balancing policy-making with governance in order to provide solutions. It also examines the importance of developing a governance process that encourages and accommodates juxtaposition in a way that ensures that the effect of independent policy-making is understood upon the success or otherwise of policies across a range of contexts and problems. Given the in-depth nature of the text, it is of interest to academics, researchers and professionals in the field.
The thoroughly updated Endocrine Secrets, 6th Edition continues the tradition of the highly popular Secrets Series®, offering fast answers to the most essential clinical endocrinology questions. A user-friendly Q&A format, replete with valuable pearls, tips, and memory aids, helps you to learn and study efficiently. It all adds up to a perfect concise board review or handy clinical endocrinology resource. Expedite your reference and review with a question-and-answer format that's conversational and easy to read. Zero in on key information with bulleted lists, mnemonics, practical tips from prominent endocrinologists, and "Key Points" boxes that provide a concise overview of important board-relevant content. Quickly review essential material with a chapter containing the "Top 100 Secrets" in endocrinology. Take your Secrets anywhere thanks to a convenient, pocket-sized design! Remain at the forefront of medical endocrinology with updates on new techniques and technologies, as well as changing treatment options and drug information. Equip yourself for effective practice with coverage of the most current developments in obesity management, weight loss drugs, and bariatric surgery; the newest guidelines for the pharmacological treatment of type 2 diabetes mellitus; and much more. Make use of practical tips on intensive insulin therapy, and apply evidence-based techniques to achieve appropriate glucose control in hospitalized patients and effectively manage thyroid cancer. Access the latest research concerning the benefits and risks of the wide range of osteoporosis therapies.
The continual explosion of information technology and the need for better data collection and management methods has made data mining an even more relevant topic of study. Books on data mining tend to be either broad and introductory or focus on some very specific technical aspect of the field. This book is a series of seventeen edited OC student-authored lecturesOCO which explore in depth the core of data mining (classification, clustering and association rules) by offering overviews that include both analysis and insight. The initial chapters lay a framework of data mining techniques by explaining some of the basics such as applications of Bayes Theorem, similarity measures, and decision trees. Before focusing on the pillars of classification, clustering and association rules, the book also considers alternative candidates such as point estimation and genetic algorithms. The book''s discussion of classification includes an introduction to decision tree algorithms, rule-based algorithms (a popular alternative to decision trees) and distance-based algorithms. Five of the lecture-chapters are devoted to the concept of clustering or unsupervised classification. The functionality of hierarchical and partitional clustering algorithms is also covered as well as the efficient and scalable clustering algorithms used in large databases. The concept of association rules in terms of basic algorithms, parallel and distributive algorithms and advanced measures that help determine the value of association rules are discussed. The final chapter discusses algorithms for spatial data mining. Sample Chapter(s). Chapter 1: Point Estimation Algorithms (397 KB). Contents: Point Estimation Algorithms; Applications of Bayes Theorem; Similarity Measures; Decision Trees; Genetic Algorithms; Classification: Distance Based Algorithms; Decision Tree-Based Algorithms; Covering (Rule-Based) Algorithms; Clustering: An Overview; Clustering Hierarchical Algorithms; Clustering Partitional Algorithms; Clustering: Large Databases; Clustering Categorical Attributes; Association Rules: An Overview; Association Rules: Parallel and Distributed Algorithms; Association Rules: Advanced Techniques and Measures; Spatial Mining: Techniques and Algorithms. Readership: An introductory data mining textbook or a technical data mining book for an upper level undergraduate or graduate level course.
Physics of Optoelectronics focuses on the properties of optical fields and their interaction with matter. Understanding that lasers, LEDs, and photodetectors clearly exemplify this interaction, the author begins with an introduction to lasers, LEDs, and the rate equations, then describes the emission and detection processes. The book summarizes and reviews the mathematical background of the quantum theory embodied in the Hilbert space. These concepts highlight the abstract form of the linear algebra for vectors and operators, supplying the "pictures" that make the subject more intuitive. A chapter on dynamics includes a brief review of the formalism for discrete sets of particles and continuous media. It also covers the quantum theory necessary for the study of optical fields, transitions, and semiconductor gain. This volume supplements the description of lasers and LEDs by examining the fundamental nature of the light that these devices produce. It includes an analysis of quantized electromagnetic fields and illustrates inherent quantum noise in terms of Poisson and sub-Poisson statistics. It explains matter-light interaction in terms of time-dependent perturbation theory and Fermi's golden rule, and concludes with a detailed discussion of semiconductor emitters and detectors.
The Compendium of Organic Synthetic Methods serves as a handy desktop reference for organic chemists to browse new reactions and transformations of interest, facilitating the search for functional group transformations in the original literature of organic chemistry. Volume 13 contains both functional group transformations and carbon-carbon bond forming reactions from the literature in the years 2005-8. It presents examples of published reactions for the preparation of monofunctional compounds. The Compendium of Organic Synthetic Methods series facilitates the search for quality, selected functional group transformations, organized by reacting functional group of starting material and functional group formed, with full references to each reaction Presents examples of published reactions for the preparation of monofunctional compounds from the literature of 2005-8 Provides a handy reference and a valuable tool to the working organic chemist, allowing a quick check of known organic transformations Stringent criteria for inclusion of reactions, including real synthetic utility of reactions, reagents readily available or easily prepared and handled in the laboratory
In Cannabis Pharmacy, expert Michael Backes offers evidence-based information on using cannabis to treat an array of ailments and conditions. He provides information on how cannabis works with the body's own system, how best to prepare and administer it, and how to modify and control dosage. This newly revised edition is now completely up-to-date with the latest information on the body's encannabinoid system, which is now understood to control emotion, appetite, and memory, delivery and dosing of cannabis, including e-cigarette designs, additional varietals, and a new system for classification, as well as 21 additional ailments and conditions that can be treated with medical marijuana. There are currently more than 4.2 million medical cannabis patients in the United States, and there are 29 states plus the District of Columbia where medical cannabis is legal.
An understanding of scale and scaling effects is of central importance to a scientific understanding of the world. With Extreme Science, help middle and high school biology, Earth science, chemistry, physics, and math students develop quantitative evaluation. Comprehending scale at the largest and smallest levels is where a quantitative understanding of the world begins.
Covering preventive, non-invasive, and natural treatments, Textbook of Natural Medicine, 4th Edition offers more than just alternative medicine. It promotes an integrated practice that can utilize natural medicine, traditional Western medicine, or a combination of both in a comprehensive, scientific treatment plan. Based on a combination of philosophy and clinical studies, Textbook of Natural Medicine helps you provide health care that identifies and controls the underlying causes of disease, is supportive of the body's own healing processes, and is considerate of each patient's unique biochemistry. Internationally known authors Joseph Pizzorno and Michael Murray include detailed pharmacologic information on herbs and supplements, plus evidence-based coverage of diseases and conditions to help you make accurate diagnoses and provide effective therapy. Comprehensive, unique coverage makes this book the gold standard in natural medicine. A scientific presentation includes the science behind concepts and treatments, and discusses Western medical treatments and how they can work with natural medicine in a comprehensive treatment plan; if natural medicine is not effective, this book recommends the Western treatment. Coverage of pharmacology of natural medicines includes the uses and potential dangers of nearly 80 herbal medicines, special nutrients, and other natural agents, addressing topics such as general information, chemical composition, history, pharmacology, clinical applications dosage, and toxicology. In-depth, evidence-based coverage of 73 diseases and conditions includes key diagnostic criteria, pathophysiology of diseases, and therapeutic rationales. Coverage of potential interactions between drugs, herbs, and supplements ensures the safest possible use for each of 79 herbs and supplements. Diagnostic procedures include practical, easy-to-follow descriptions of evidence-based techniques plus discussions of clinical application of diet analysis, food allergy testing, immune function assessment, fatty acid profiling, hair mineral analysis, and other diagnostic approaches. Common therapeutic modalities are described and reviewed, including botanical medicine, nutritional therapy, therapeutic fasting, exercise therapy, hydrotherapy, counseling, acupuncture, homeopathy, and soft tissue manipulation. Coverage of syndromes and therapies helps in understanding the underlying causes of diseases by discussing topics such as food reactions, functional toxicology, sports nutrition, stress management, and breathing pattern disorders. Coverage of the philosophy of natural medicine includes its history and background, with discussions of toxicity, detoxification, and scientific documentation of the healing actions of nature and natural substances. Internationally known authors Joseph Pizzorno and Michael Murray and more than 90 expert contributors provide material that is up to date, accurate, and informed. More than 10,000 research literature citations show that the content is based on science rather than opinions or anecdotes. 13 useful appendices offer quick lookup of frequently used charts, handouts, and information. New chapters are included on hot topics such as female infertility, medicinal mushrooms, natural products and quality control, pregnancy health and primary prevention, and Vitamin K; new appendices include a supplier certification questionnaire and cervical escharotics treatment. Thorough updates ensure that you use only the most current research and provide the most effective treatment of patients. Tabs in Specific Health Problems section separate more than 70 alphabetized diseases/conditions. One convenient volume replaces the cumbersome two-volume set for easy, convenient reference. Electronic access is available via Pageburst, making it easy to search topics, drugs, herbs and supplements, and diseases and conditions. Sold separately.
This work is not an anatomical atlas nor textbook (like that of McAlpine and Anderson) nor an angiographical atlas (like that of Vlodaver et al.); it is a short and comprehensive survey of the many variations of the intrinsic cardiac vessels. The reader's attention is focused on the numerous structural details and peculiarities of the human coronary arteries. The many unique features have been revealed by meticulous dissection and present an excellent documentation. All in all, this study represents an up-to-date review of morphology of the coronary arteries.
AIDS treatments continues to evolve. Now, so does the definitive reference on this complex and challenging subject! "AIDS Therapy, 3rd Edition" not only brings you comprehensive guidance on the latest treatments for HIV/AIDS and the full range of related disorders and syndromes, but also comes with access to updates online—so you can always tap into the most current therapy guidelines. Written by a "who's who" of leading global experts, the new edition of this classic reference is a must for any clinician who manages patients with HIV/AIDS. The most comprehensive coverage available on AIDS treatment equips you to meet any clinical challenge. Contributions from a large cast of noted international authorities put global "best practices" at your fingertips. Advice from some of the most respected experts in the field helps you manage your patients confidently. Available with a companion website allowing you to access the latest treatment guidelines year after year.
Given the unprecedented demands on the U.S. military since 2001 and the risks posed by stress and trauma, there has been growing concern about the prevalence and consequences of sleep problems. This first-ever comprehensive review of military sleep-related policies and programs, evidence-based interventions, and barriers to achieving healthy sleep offers a detailed set of actionable recommendations for improving sleep across the force.
Due to the generous representation of the afferent visual system within the brain, neurological disease may disrupt vision as a presenting symptom or as a secondary effect of the disease. Conversely, early developmental disturbances of vision often disrupt ocular motor control systems, giving rise to complex disorders such as nystagmus, strabismus, and torticollis. The signs and symptoms of neurological disease are elusive by their very nature, presenting a confounding diagnostic challenge. Neurological medications and neurosurgical treatments can produce neuro-ophthalmological dysfunction that can be difficult to distinguish from disease progression. Affected patients may experience substantial delays in diagnosis, and are often subjected to extensive (and expensive) diagnostic testing. Scientific articles pertaining to specific disorders are scattered throughout medical subspecialty journals. These children continue to "fall through the cracks" of our medical education system. The increasing recognition that pediatric neuro-ophthalmology comprises a distinct set of diseases from those seen in adults has led to its emergence as a dedicated field of study. "Since the original publication of Pediatric Neuro-Ophthalmology nearly fourteen years ago, interest in the field has burgeoned. Pediatric ophthalmology and pediatric neurology subspecialty conferences often include symposia dedicated to recent advances in pediatric neuro-ophthalmology. Technical advances in neuroimaging have given rise to a more integrated mechanistic classification of neuro-ophthalmological disease in children. Our understanding of neurodevelopmental disorders of the visual system has expanded, longstanding monoliths have been dissembled into component parts, basic molecular mechanisms have taken center stage, and genetic underpinnings have become definitional. Evolutionary alterations can now be observed at the level of the gene, adding a new dimension to our understanding of disease pathogenesis. New classifications now encompass clinically disparate conditions. Descriptive definitions have been supplanted by mechanistic ones, and clinical definitions superseded by genetic ones. Our concept of disease pathogenesis has been revised and in some cases overturned. Bearing witness to these remarkable advancements has compelled me to enhance and expand the first edition of Pediatric Neuro-Ophthalmology into this new and revised one. "In the first edition of this book, our goal was to present the clinical characteristics, diagnostic evaluation, and therapeutic options for the common neuro-ophthalmologic disorders of childhood. In so doing, we designed the book to be provide a narrative journey through the thought processes involved in the clinical management of these disorders. In this edition, I have retained the basic narrative format of original book, while expanding the exploration of these complex visual disorders in the context of the many new scientific advancements and discoveries that have come to light. These conditions are fun to diagnose, fascinating to understand, and gratifying to manage." --from the Preface to the 2nd Edition.
First published in 1986 under the editorial direction of Dr. Henry J.M. Barnett, Stroke: Pathophysiology, Diagnosis, and Management continues to provide the dependable, current answers you need to effectively combat the increasing incidence of this disease. Dr. J.P. Mohr, together with new associate editors Philip A. Wolf, James C. Grotta, Michael A. Moskowitz, Marc Mayberg, and Rüdiger von Kummer as well as a multitude of expert contributors from around the world, offer you updated and expanded coverage of mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more, equipping you to understand the latest scientific discoveries and make effective use of the newest approaches to diagnosis and treatment. Gain fresh perspectives and up-to-date insights from the world’s leading authorities on the pathophysiology, diagnosis, and management of stroke. Access the comprehensive, expert clinical guidance you need to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Make efficient and accurate diagnoses with the aid of abundant full-color CT images and pathology slides. Stay up to date on hot topics such as mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more.
Chromic or colour related phenomena are produced in response to a chemical or physical stimulus. This new edition will update the information on all those areas where chemicals or materials interact with light to produce colour, a colour change, or luminescence especially in the imaging, analysis, lighting and display areas. The book has been restructured to show greater emphasis on applications where 'coloured' compounds are used to transfer energy or manipulate light in some way therefore reducing the details on classical dyes and pigments. In the past eight years, since the previous edition, there has been a remarkable increase in the number of papers and reviews being produced reflecting the growth of interest in this area. This ongoing research interest is matched by a large number of new technological applications gaining commercial value covering e.g. biomedical areas, energy, data storage, physical colour, bio-inspired materials and photonics. This book appeals to industrial chemists, professionals, postgraduates and as high level recommended reading for colour technology courses.
A practical manual of protocols for achieving expression of foreign genes in mammalian cells. It includes some very new techniques such as PCR-based expression. The author gives a theoretical introduction to the protocols and compares the strengths and weaknesses.
The most comprehensive and up-to-date optics resource available Prepared under the auspices of the Optical Society of America, the five carefully architected and cross-referenced volumes of the Handbook of Optics, Third Edition, contain everything a student, scientist, or engineer requires to actively work in the field. From the design of complex optical systems to world-class research and development methods, this definitive publication provides unparalleled access to the fundamentals of the discipline and its greatest minds. Individual chapters are written by the world's most renowned experts who explain, illustrate, and solve the entire field of optics. Each volume contains a complete chapter listing for the entire Handbook, extensive chapter glossaries, and a wealth of references. This pioneering work offers unprecedented coverage of optics data, techniques, and applications. Volume IV covers optical properties of materials, nonlinear optics, and quantum optics.
The process of economic globalization, as product and capital markets have become increasingly integrated since WWII, has placed huge, and it is argued by some, irresistible pressures on the world's 'insider' stakeholder oriented corporate governance systems. Insider corporate governance systems in countries such as Germany, so the argument goes, should converge or be transformed by global product and capital market pressures to the 'superior' shareholder oriented 'outsider' corporate governance model prevalent in the UK and the US. What these pressures from globalization are, how they manifest themselves, whether they are likely to cause such a convergence/transformation and whether these pressures will continue, lie at the heart of the exploration in this volume. The Globalization of Corporate Governance provides a detailed analysis of the evolution of the key corporate governance systems in the UK, the US and Germany from the perspective of the development of economic globalization. As such it is a valuable resource for those interested in how economic and legal reforms interact to produce change within corporate governance systems.
The Interventional Radiology volume of the landmark reference Abrams' Angiography has now been expanded and thoroughly revised to reflect dynamic advances in interventional radiology. More than 60 contributors representing a "Who's Who" of the specialty provide comprehensive, step-by-step coverage of all contemporary vascular and nonvascular interventional procedures. Major sections discuss today's equipment and describe interventions for specific disorders of each organ system, as well as for trauma, pediatric diseases, abscess drainage, and miscellaneous disorders. More than 1,100 illustrations complement the text. This edition incorporates an extensive new section on interventional oncologic procedures. The section covers all organ-specific cancers for which interventional therapies are used. Other sections include artervenous malformations, liver diseases, arterial occlusive disease, aneurysms, traumatic arterial injuries, hemorrhage, and venous diseases. It also has full color.
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