The book is based on lectures given at the TASI summer school of 2010. It aims to provide advanced graduate students, postdoctorates and senior researchers with a survey of important topics in particle physics and string theory, with special emphasis on applications of methods from string theory and quantum gravity in condensed matter physics and QCD (especially heavy ion physics).
Provides synthetic chemists with a method for rapid retrieval of information from the literature, listing material by reaction type rather than by author name or publication date. Each updated volume presents the latest synthetic methods for preparation of monofunctional and difunctional compounds. The organization is logical and easy to follow; sections are arranged according to the possible interconversions between the major functional groups. Enables synthetic chemists to keep abreast of recent developments and retrieve a specific piece of information quickly and easily.
The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.
Cognitive and Intellectual Disabilities: Historical Perspectives, Current Practices, and Future Directions provides thorough coverage of the causes and characteristics of cognitive and intellectual disabilities (formerly known as mental retardation) as well as detailed discussions of the validated instructional approaches in the field today. Features include: A companion website that offers students and instructors learning objectives, additional activities, discussion outlines, and practice tests for each chapter of the book An up-to-date volume that reflects the terminology and criteria of the DSM-V and is aligned with the current CEC standards Teaching Applications: presents the strongest coverage available in any introductory text on instructional issues and applications for teaching students with cognitive and intellectual disabilities A unique chapter on "Future Issues" that explores the philosophical, social, legal, medical, educational, and personal issues that professionals and people with cognitive and intellectual disabilities face This comprehensive and current introductory textbook is ideally suited for introductory or methods courses related to cognitive and intellectual disabilities.
This book examines the interactions between implants and biological fluids that cause fouling in biosensors and the serious issue of thrombus formation suitable for professional researchers in academia and industry and postgraduate students.
Organic Synthesis 5e provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature.? There have been advancements in organic reactions, particularly organometallic reactions, and there is a need to show how these advancements have influenced current organic synthesis. The goal is to revise and update the examples of reaction examples taken from the synthesis literature from about 2017-2023. The reactions illustrate those that are used most often in modern organic synthesis, but recent examples will show their current relevance.? Where new approaches and new reactions have been developed for organic synthesis, examples will be added as new material. - Provides new content, reaction examples, and study problems from recent research? - Features improved organization, new art, and new chapter content on process chemistry and green organic chemistry - Includes revised homework for each chapter, with new examples and questions?
The steady downscaling of device-feature size combined with a rapid increase in circuit complexity as well as the introduction of new device concepts based on non-silicon-material systems poses great challenges for device and circuit designers. One of the major tasks is the development of new and improved device models needed for accurate device and circuit design. Another task is the development of new circuit-simulation tools to handle very large and complex circuits. This book addresses both these issues with up-to-date reviews written by leading experts in the field.The first three chapters of the book discuss advanced device models both for existing technologies and for new, emerging technologies. Among the topics covered are models for MOSFETs, thin-film transitors (TFTs), and compound semiconductor devices, including GaAs HEMTs and HFETs, heterodimensional devices, quantum-tunneling devices, as well as wide-bandgap devices. Chapters 4 and 5 discuss advanced circuit simulators that hold promise for handling circuits of much higher complexity than what is possible for typical state-of-the-art circuit simulators today.
This issue of the Interventional Cardiology Clinics edited by Michael Lee covers all key aspects of complex coronary intervention. Topics include, but are not limited to: Saphenous Vein Interventions, Atherectomy Devices for the Treatment of Calcified Lesions, Bifurcation Stenting, Chronic Total Occlusion, Multivessel Coronary Artery Disease, Management of Complications (Perforation/Dissection/Thrombosis), Antithrombotic Therapy in Percutaneous Coronary Intervention, and Acute Myocardial Infarction/Thrombectomy.
Heat exchangers with minichannel and microchannel flow passages are becoming increasingly popular due to their ability to remove large heat fluxes under single-phase and two-phase applications. Heat Transfer and Fluid Flow in Minichannels and Microchannels methodically covers gas, liquid, and electrokinetic flows, as well as flow boiling and condensation, in minichannel and microchannel applications. Examining biomedical applications as well, the book is an ideal reference for anyone involved in the design processes of microchannel flow passages in a heat exchanger. - Each chapter is accompanied by a real-life case study - New edition of the first book that solely deals with heat and fluid flow in minichannels and microchannels - Presents findings that are directly useful to designers; researchers can use the information in developing new models or identifying research needs
Safe Water in Healthcare: A Practical and Clinical Guide enables users from different disciplines to understand all types of waterborne hazards that can pose a risk to those who might be exposed, the events which cause them to be present, what may precipitate an increase in their levels that may cause harm, and how they can be avoided or managed to reduce risk. The handbook highlights microorganisms that can cause infections, modes of transmission, the infections they cause, and risks. The book's authors draw from their extensive practical experience assisting with day-to-day problems that range from minor issues to outbreaks. The book includes case studies on the growth of biofilms and where they cause problems in water systems as well as providing practical answers to a majority of issues that arise in healthcare water and drainage systems. This is an accessible handbook that fills the gaps for those without technical knowledge for a complex but important area of infection control. It provides practical guidance for professionals who are required to design, manage and maintain water systems and help them manage associated infection outbreaks. - Discusses waterborne pathogens, their detection, identification and surveillance and describes the extent and range of recognized and emerging waterborne microorganisms as well as the diseases that occur and consequences to patients and staff - Covers hazards that can cause harm within water systems and associated equipment, the circumstances or factors that increase the risks, and the multiple modes of transmission of waterborne pathogens - Explains the importance of good design, including the type of design, management, hardware and software that can help manage and control the presence of waterborne pathogens. - Highlights who needs to be involved at each stage to ensure that patients are kept safe from waterborne pathogens, taking into account current legislation and best practices guidance
The North Carolina Gazetteer first appeared to wide acclaim in 1968 and has remained an essential reference for anyone with a serious interest in the Tar Heel State, from historians to journalists, from creative writers to urban planners, from backpackers to armchair travelers. This revised and expanded edition adds approximately 1,200 new entries, bringing to nearly 21,000 the number of North Carolina cities, towns, crossroads, waterways, mountains, and other places identified here. The stories attached to place names are at the core of the book and the reason why it has stood the test of time. Some recall faraway places: Bombay, Shanghai, Moscow, Berlin. Others paint the locality as a little piece of heaven on earth: Bliss, Splendor, Sweet Home. In many cases the name derivations are unusual, sometimes wildly so: Cat Square, Huggins Hell, Tater Hill, Whynot. Telling us much about our own history in these snapshot histories of particular locales, The North Carolina Gazetteer provides an engaging, authoritative, and fully updated reference to place names from all corners of the Tar Heel State.
The third edition provides thorough coverage of the causes and characteristics of intellectual disabilities as well as detailed discussions of the validated instructional approaches in the field today. A revised "Future Directions" chapter explores the most recent philosophical, social, legal, medical, educational, and personal issues that professionals and people with intellectual disabilities face. All chapters have been updated with recent developments in research and the newest terminology being used in the field. This comprehensive and current introductory textbook is ideally suited for introductory or methods courses related to intellectual disabilities.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
Family Therapy, second edition, is a fully updated and essential textbook that provides students and practitioners with foundational concepts, theory, vocabulary, and skills to excel as a family therapist. This book is a primer of how family therapists conceptualize the problems that people bring to therapy, utilize basic therapeutic skills to engage clients in the therapeutic process, and navigate the predominant models of family therapy. The text walks readers through the process of thinking like a family therapist, and each chapter utilizes various learning tools to help the reader further understand and apply the concepts. Chapters explore the history, context, and dominant theories of family therapy, as well as diversity, ethics, empathy, structuring sessions, and assessment. Written in a comprehensive and approachable style, this text provides readers with the foundational skills and tools essential for being a family therapist, and allows students and practitioners to work relationally and systemically with clients. The second edition widens its scope of the family therapy field with updated research and four brand-new chapters. This is an essential text for introductory family therapy courses and a comprehensive resource for postgraduate students and the next generation of family therapists.
This book provides an analysis of children’s play across many different cultural communities around the globe. Each chapter discusses children’s play as an activity important for formal and informal education, mental health and childhood well-being, and children’s hobbies and past-times. Traditional, modern and postmodern play forms are discussed and probed for their meaning within a contemporary global community. Authors address the functions that this phenomenon serves for indigenous cultures and the problems that arise due to the globalization of educational and social resources. Issues that are covered include the importance of conceptualizing the relationship between play and culture, how play varies both within and between cultures, children’s non-play activities in relation to play activities, how play is learned and how adults, parents and teachers, as well as older peers and siblings, are all important influences on the play of children. Questions that are raised include: Is it fair to emphasize the importance of certain kinds of play, such as social pretense play? Is this ethnocentric? Is the mastery of certain forms of play (e.g. socio-dramatic play) during the early years critical in the acculturation process? How are different cultures incorporating literacy props in play, or otherwise developing early educational programmes that use play educationally to foster literacy acquisition? These and many other questions or issues are taken up in this volume. At the heart of the book is a focus on human rights, in particular the Child’s Right to Play as stated in the UN Convention on the Rights of the Child. The book is committed to the principle of all children reaching their full potential and the enhancement of their families, communities, and cultures through play.
Thoroughly revised and reorganized, this 2nd edition offers you meticulous how-to-do-it guidance on performing today’s top radiographically guided regional anesthesia and pain management techniques. Renowned experts explain how to make optimal use of fluoroscopy, MRI, and CT to pinpoint the exact anatomic site for each procedure. Provides fluoroscopic, MR, and CT images coupled with distinct line drawings for each procedure to ensure proper positioning and easy application of techniques. Offers easy-to-follow step-by-step descriptions addressing every aspect of patient positioning, the use of radiographic solutions for tissue-specific enhancement, and correct techniques for anesthesia/analgesia administration so you can be sure your patient will be pain free throughout the procedure. Discusses possible complications to help you avoid mistakes. Includes descriptions of procedures for each image guided technique as well as the approaches available for such imaging so you can choose the correct procedure for every patient. Features two new sections Advanced Techniques and Emerging Techniques, incorporates new procedures into the upper and lower extremity and head and neck chapters, and revises all other chapters substantially to put you on the cusp of the latest advances in the field. Uses nearly 1,600 crisp illustrations, 50% new to this edition, to illuminate every concept. Presents a complete reorganization by body region and focused content to help you get to the information you need quickly.
Management of Marine Plastic Debris gives a thorough and detailed presentation of the global problem of marine plastics debris, covering every aspect of its management from tracking, collecting, treating and commercial exploitation for handing this anthropogenic waste. The book is a unique, essential source of information on current and future technologies aimed at reducing the impact of plastics waste in the oceans. This is a practical book designed to enable engineers to tackle this problem—both in stopping plastics from getting into the ocean in the first place, as well as providing viable options for the reuse and recycling of plastics debris once it has been recovered. The book is essential reading not only for materials scientists and engineers, but also other scientists involved in this area seeking to know more about the impact of marine plastics debris on the environment, the mechanisms by which plastics degrade in water and potential solutions. While much research has been undertaken into the different approaches to the increasing problem of plastics marine debris, this is the first book to present, evaluate and compare all of the available techniques and practices, and then make suggestions for future developments. The book also includes a detailed discussion of the regulatory environment, including international conventions and standards and national policies. - Reviews all available processes and techniques for recovering, cleaning and recycling marine plastic debris - Presents and evaluates viable options for engineers to tackle this growing problem, including the use of alternative polymers - Investigates a wide range of possible applications of marine plastics debris and opportunities for businesses to make a positive environmental impact - Includes a detailed discussion of the regulatory environment, including international conventions and standards and national policies
This is the first authored volume to offer a detailed, integrated analysis of the field of eating problems and disorders with theory, research, and practical experience from community and developmental psychology, public health, psychiatry, and dietetics. The book highlights connections between the prevention of eating problems and disorders and theory and research in the areas of prevention and health promotion; theoretical models of risk development and prevention (e.g., developmental psychopathology, social cognitive theory, feminist theory, ecological approaches); and related research on the prevention of smoking and alcohol use. It is the most comprehensive book available on the study of prevention programs, especially for children and adolescents. The authors review the spectrum of eating problems and disorders, the related risk and protective factors, the models that have guided prevention efforts to date, the literature on the studies of prevention, and suggestions for curriculum and program development and evaluation. The book concludes with a new prevention program based on the Feminist Ecological Developmental model. The 800 + references highlight work done around the world. The Prevention of Eating Problems and Eating Disorders addresses: * methodologies for assessing and establishing prevention; * the implications of neuroscience for prevention; * dramatic increases in the incidence of obesity; * the role of boys, men, and the media on body image; * prevention programming for minority groups; and * whether to focus on primary or secondary prevention. Intended for clinicians and academicians from disciplines such as health, clinical, developmental, and community psychology; social work; medicine; and public health; this book is also an ideal text for advanced courses on eating disorders.
Better understand your patients' complete medical profile and provide the best possible care! This one-of-a-kind reference provides a practical look at neurological disease and how it affects, and is affected by, other disease. It helps neurologists manage patients with co-existing medical conditions, and helps internists understand and treat the neurological manifestations of patients' primary diseases. A new emphasis on diagnosis and management—including advances in pharmacology, genetic-based therapies, and new imaging techniques—makes this 4th Edition more clinically valuable than ever! Focused content highlights the vital links between neurology and other medical specialties, promoting a better understanding of all disciplines, as well as enhancing patient care. Comprehensive coverage of advances in pharmacology, such as new antibiotics for infectious diseases, helps you successfully manage a full range of diseases and disorders. An interdisciplinary team of authors provides insight into the neurological aspects of the conditions you see in daily practice. Easy-to-read chapters apply equally well to neurologists and non-neurologists, providing essential knowledge that covers the full spectrum of medical care. Expanded chapters emphasize key diagnostic and therapeutic information, including appropriate testing and treatments for neurological disease. An emphasis on advances in pharmacology and new imaging techniques helps you better manage your patients and understand how new drugs or therapies will affect your patients and practice. New chapters on auditory and vestibular disease, ocular disease, and cutaneous disease provide a well-rounded look at the specialty. Updated illustrations make complex concepts easier to understand and apply.
Derived from the authors' long-running course presented at the International Academy of Pathology, this second edition, now with color illustrations, continues the tradition of its predecessor as being the concise and complete diagnostic guide to the endometrial biopsy. The text is structured so as to present a logical approach to formulating a pathologic diagnosis from the diverse array of tissue received in the surgical pathology laboratory. Color illustrations show typical artifacts and distortion, and explain their impact on diagnostic interpretation. Each chapter includes a section summarizing the features that must be discussed in the final pathology report.
50th Anniversary Edition of the groundbreaking case-based pharmacotherapy text, now a convenient two-volume set. Celebrating 50 years of excellence, Applied Therapeutics, 12th Edition, features contributions from more than 200 experienced clinicians. This acclaimed case-based approach promotes mastery and application of the fundamentals of drug therapeutics, guiding users from General Principles to specific disease coverage with accompanying problem-solving techniques that help users devise effective evidence-based drug treatment plans. Now in full color, the 12th Edition has been thoroughly updated throughout to reflect the ever-changing spectrum of drug knowledge and therapeutic approaches. New chapters ensure contemporary relevance and up-to-date IPE case studies train users to think like clinicians and confidently prepare for practice.
The current book attempts to give a glimpse of the scientific life of Michael Rossmann. The book begins with his very interesting and moving autobiography. His enormous energy must have been evident already from early childhood when he and his mother had to emigrate from Nazi-Germany to England, via The Netherlands. Starting school with a new language was a challenge that he managed well with the assistance of understanding teachers. Crystallography soon became the tool to explore new worlds, unknown to everybody. With a skill for mathematics, he realized that the transform of a molecular structure in the diffraction pattern could be used for analysis of both symmetry and structural relationships. This method, molecular replacement (MR, also the initials of his name) became one of his great successes of his career. The previous book by him in this series (Selected Papers by Michael G Rossmann with Commentaries) covers his main contributions in this area.With an interest in symmetry, viruses became obvious objects to study. Rossmann attacked these monstrously large molecular assemblies with his unfailing energy and his appetite for real challenges. The amazing variation of molecular arrangements with icosahedral symmetry is truly amazing. This book includes a selection of reports of the structures of some giant viruses. As always, knowing the structure enhances the understanding of function greatly, in the case of viruses the mechanism of infection is a key problem. Rossmann has contributed many central insights in this area.Thus, this book is of interest both as an interesting personal story but also for research into viruses that repeatedly plague all living organisms on the planet, right now in the form of the corona virus pandemic.
As the Internet becomes increasingly heterogeneous, the issue of congestion control becomes ever more important. In order to maintain good network performance, mechanisms must be provided to prevent the network from being congested for any significant period of time. Michael Welzl describes the background and concepts of Internet congestion control, in an accessible and easily comprehensible format. Throughout the book, not just the how, but the why of complex technologies including the Transmission Control Protocol (TCP) and Active Queue Management are explained. The text also gives an overview of the state-of-the-art in congestion control research and an insight into the future. Network Congestion Control: Presents comprehensive, easy-to-read documentation on the advanced topic of congestion control without heavy maths. Aims to give a thorough understanding of the evolution of Internet congestion control: how TCP works, why it works the way it does, and why some congestion control concepts failed for the Internet. Explains the Chiu/Jain vector diagrams and introduces a new method of using these diagrams for analysis, teaching & design. Elaborates on how the theory of congestion control impacts on the practicalities of service delivery. Includes an appendix with examples/problems to assist learning. Provides an accompanying website with Java tools for teaching congestion control, as well as examples, links to code and projects/bibliography. This invaluable text will provide academics and researchers in computer science, electrical engineering and communications networking, as well as students on advanced networking and Internet courses, with a thorough understanding of the current state and future evolution of Internet congestion control. Network administrators and Internet service and applications providers will also find Network Congestion Control a comprehensive, accessible self-teach tool.
Health Psychology takes a truly international and critical biopsychosocial approach, providing students with a holistic understanding of health behaviour, culture and change. Thoroughly updated with the latest research, this comprehensive introduction to foundational and cutting-edge topics in health psychology gives you the tools you need to critically appraise theory and research, and to apply this knowledge to real-world public health issues. Praised for its coverage of social justice, macro-social and cultural issues in health, this edition features three new chapters on parenting and health, responses to the COVID-19 pandemic, and gender-affirmative healthcare for transgender people. Now in full colour, it also includes updated pedagogy, with international Key Studies, Critical Discussions and Insights boxes to extend your learning. Written by experts in the field, this must-read for students of Health Psychology, Health Promotion and Health Behaviour demonstrates how theory and research learned in the classroom impacts public policy around the world. David F. Marks is a psychologist specializing in Health Psychology, Mental Imagery and Consciousness research. Michael Murray is Emeritus Professor of Social and Health Psychology at Keele University. Emee Vida Estacio is a chartered psychologist, author, speaker and health promotion specialist. Rachel A. Annunziato is Professor of Psychology at Fordham University. Abigail Locke is Professor of Critical Social and Health Psychology and Head of School at Keele University. Gareth J. Treharne is Professor of Psychology at te Whare Wananga o Otago (the University of Otago).
This thesis proposes a method that plans trajectories for autonomous agents to enable them to fulfil different tasks while ensuring the collision-free movement. The agents are locally controlled and connected over an unreliable communication network that may induce packet losses and transmission delays. Further sensors e.g. for a distance measurement are not used and communication should only be invoked if it is necessary to avoid a collision. The basic problem occurs for two agents. The first agent can change its trajectory at any time without regard to the second agent, which has to ensure the collision avoidance. To this aim it adapts its trajectory based only on local data and communicated information about the current and future movement of the first agent. A control unit for the second agent is introduced that has to execute four tasks to ensure the control aims: 1. Estimation of the current network properties. 2. Prediction of the movement of the stand-on agent. 3. Invocation of communication whenever the local data becomes too uncertain. 4. Planning of collision avoiding trajectories. The main result of the thesis is a novel control method for mobile agents that solves the four tasks leading to a proven collision avoidance. The method consists of a delay estimator, a prediction unit, an event generator and a trajectory planning unit. The method can be used for different types of agents (e.g. UAVs or cars) with only slight modifications. The proposed method is tested and evaluated through simulations and experiments with both, two quadrotors and two nonholonomic robots.
The rapidly expanding field of ionic liquids is now a major topic of academic and industrial interest with numerous existing and potential applications. This book provides a comprehensive introduction to the field.
With an emphasis on global advantage, the text offers a comprehensive examination of regional and international issues to provide a complete, accurate and up-to-date explanation of the strategic management process. New coverage on environmental concerns and emerging technologies as well as examples and cases from Australia, New Zealand and Asia-Pacific serve to engage students while updated international content demonstrates how strategic management is used in the global economy. The text takes a 'resource-based' approach, which requires the examining of a firm's unique bundling of its internal resources. This text is appropriate for upper-level undergrad, usually third year; post grad in Masters courses.
Presents the most innovative results in carbene chemistry, setting the foundation for new discoveries and applications The discovery of stable carbenes has reinvigorated carbene chemistry research, with investigators seeking to develop carbenes into new useful catalysts and ligands. Presenting the most innovative and promising areas of carbene research over the past decade, this book explores newly discovered structural, catalytic, and organometallic aspects of carbene chemistry, with an emphasis on new and emerging synthetic applications. Contemporary Carbene Chemistry features contributions from an international team of pioneering carbene chemistry researchers. Collectively, these authors have highlighted the most interesting and promising areas of investigation in the field. The book is divided into two parts: Part 1, Properties and Reactions of Carbenes, explores new findings on carbene stability, acid-base behavior, and catalysis. Carbenic structure and reactivity are examined in chapters dedicated to stable carbenes, carbodicarbenes, carbenes as guests in supramolecular hosts, tunneling in carbene and oxacarbene reactions, and ultrafast kinetics of carbenes and their excited state precursors. Theoretical concerns are addressed in chapters on computational methods and dynamics applied to carbene reactions. Part 2, Metal Carbenes, is dedicated to the synthetic dimensions of carbenes, particularly the reactions and catalytic properties of metal carbenes. The authors discuss lithium, rhodium, ruthenium, chromium, molybdenum, tungsten, cobalt, and gold. All the chapters conclude with a summary of the current situation, new challenges on the horizon, and promising new research directions. A list of key reviews and suggestions for further reading also accompanies every chapter. Each volume of the Wiley Series on Reactive Intermediates in Chemistry and Biology focuses on a specific reactive intermediate, offering a broad range of perspectives from leading experts that sets the stage for new applications and further discoveries.
Comprehensive resource reviewing fundamentals, device physics and reliability, fabrication processes, and numerous emerging applications of oxide thin film transistor technology over performing traditional thin film transistor technologies Oxide Thin Film Transistors book presents a comprehensive overview of oxide thin film transistor (TFT) science and technology, including fundamental material properties, device operation principles, modeling, fabrication processes, and applications. Split into four sections, the book first details oxide TFT materials including material parameters, and electrical and contact properties. The next section describes oxide TFT devices including designs, reliability, and comparison with other TFT types. The third part delves into the fabrication processes of oxide TFTs. The last section provides insight into existing and emerging applications of oxide TFTs including displays, imagers, circuits, sensors, flexible electronics, and circuits. Written by a team of well-reputed researchers in the field including the inventor of the IGZO TFT, Oxide Thin Film Transistors include information on: Electronic and crystal structure of widegap oxides, covering electronic structure of n- and p-type oxide semiconductors as well as doping limit and band alignment Device physics, covering operation principles, reliability, comparison with other TFT types, and high-frequency performance Fabrication processes, covering deposition methods, gate insulators, and passivation layers Applications, covering liquid crystal, light emitting diode, and electrophoretic displays, flexible electronics, imagers, and integrated circuits Oxide Thin Film Transistors is an ideal textbook resource for students who want to learn about oxide TFTs and a useful, up-to-date reference for researchers and engineers working on oxide TFTs and in related areas.
Public health thrives on high-quality evidence, yet acquiring meaningful data on a population remains a central challenge of public health research and practice. Social monitoring, the analysis of social media and other user-generated web data, has brought advances in the way we leverage population data to understand health. Social media offers advantages over traditional data sources, including real-time data availability, ease of access, and reduced cost. Social media allows us to ask, and answer, questions we never thought possible. This book presents an overview of the progress on uses of social monitoring to study public health over the past decade. We explain available data sources, common methods, and survey research on social monitoring in a wide range of public health areas. Our examples come from topics such as disease surveillance, behavioral medicine, and mental health, among others. We explore the limitations and concerns of these methods. Our survey of this exciting new field of data-driven research lays out future research directions.
This book offers both a practical as well a theoretical approach to Solvent Microextraction (SME) and will help analytical chemists to evaluate SME for a given sample preparation. Introductory chapters overview a comparison of SME with other sample preparation methods, a summary of the technical aspects, and a detailed theoretical treatment of SME. The book then describes the practical aspects of the technique, with detailed “how to” chapters devoted to the preparation and analysis of atmospheric, solid and liquid environmental, clinical and industrial samples. This text will serve as both a handy laboratory desk-reference and an indispensible instructional tool.
Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease. Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy. The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.
From design and simulation through to testing and fabrication, this hands-on introduction to silicon photonics engineering equips students with everything they need to begin creating foundry-ready designs. In-depth discussion of real-world issues and fabrication challenges ensures that students are fully equipped for careers in industry. Step-by-step tutorials, straightforward examples, and illustrative source code fragments guide students through every aspect of the design process, providing a practical framework for developing and refining key skills. Offering industry-ready expertise, the text supports existing PDKs for CMOS UV-lithography foundry services (OpSIS, ePIXfab, imec, LETI, IME and CMC) and the development of new kits for proprietary processes and clean-room based research. Accompanied by additional online resources to support students, this is the perfect learning package for senior undergraduate and graduate students studying silicon photonics design, and academic and industrial researchers involved in the development and manufacture of new silicon photonics systems.
Awarded the Literature Prize of the VCI This comprehensive textbook describes the synthesis, characterization and technical and engineering applications of polymers. Polymers are unique molecules and have properties different from any other class of materials. We encounter them in everyday life, not only in the form of the well-known, large-volume plastics such as PE or PP or the many other special polymers, some of which are very specifically modified but also in nature as polymeric biomolecules, such as DNA. Our life, as we know it, would not only be completely different without macromolecules but it would also be biologically impossible. This textbook provides a broad knowledge of the basic concepts of macromolecular chemistry and the unique properties of this class of materials. Environmentally relevant topics, such as biopolymers and microplastic, which should not be missing in a contemporary textbook are also covered. Building on basic knowledge of organic chemistry and thermodynamics, the book presents an easy-to-understand yet in-depth picture of this very dynamic and increasingly important interdisciplinary science that involves elements of chemistry, physics, engineering, and the life sciences. Readers of this work can confirm their understanding of the text at the end of each chapter by working through a selection of exercises. In writing the book, great importance was attached to good readability despite the necessary depth of detail. It is a book that is just as suitable for students of chemistry and related courses as it is for the applied scientist in an industrial environment. The first edition of this work is so far the only textbook on polymer chemistry to be awarded the Literature Prize of the Fund of the German Chemical Industry Association in 2015.
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