Now fully revised and updated, this guide to New York City offers the incomparable expertise of National Geographic for this comprehensive guidebook to the Big Apple, illustrated with 200 color photos and ten maps.
On July 24, 1847, a band of Mormon pioneers descended into the Salt Lake Valley. Having crossed the Great Plains and hauled their wagons over the Rocky Mountains, they believed that their long search for a permanent home had finally come to an end. The valley was an arid and inhospitable place, but to them it was Zion. They settled on the edge of an immense, uncharted, and self-contained region covering over 220,000 square miles, or one-fifteenth of the area of the United States. The early-nineteenth-century explorer John Charles Fremont had just aptly named this region the Great Basin because its lakes and rivers have no outlet to the sea: its waters course down the mountains and disappear into the desert. Here, in a land that few others wanted, the Mormons hoped to live and worship in peace. Within ten years of their arrival, the Mormons had established nineteen communities, extending all the way to San Diego, California--a remarkable feat of colonization and one of the great successes of the westward movement. Desert Between the Mountains is by no means, however, a story of splendid and stoic isolation. Beginning with an explanation of the Great Basin's unique and enigmatic topography, Michael S. Durham delineates the region as a crucible for a complex and exciting narrative history. Tales of nomadic Indian tribes, Spanish ecclesiastics, intrepid furtrappers, and adventurous early explorers are brilliantly and thoroughly chronicled. Moreover, Durham depicts the Mormon way of life under the constant strain from its interaction with miners, soldiers, mountain men, the Pony Express, railroad builders, federal officials, and an assortment of other so-called Gentiles. Durham vigorously explores the dynamics of this important chapter of American history, capturing its epic sweep, its near biblical mayhem, and its unforgettable characters in an illuminating and provocative account. Desert Between the Mountains concludes with the joining of the transcontinental railroad at Promontory, Utah, in 1869, an event that marked the end of the pioneer era. This is a dramatic, multifaceted, and definitive study of the Great Basin, demonstrating, for the first time, that it is a region unified in its history as well as its geography--that today includes all of Nevada, most of Utah, and parts of five other surrounding states.
The North Carolina Gazetteer first appeared to wide acclaim in 1968 and has remained an essential reference for anyone with a serious interest in the Tar Heel State, from historians to journalists, from creative writers to urban planners, from backpackers to armchair travelers. This revised and expanded edition adds approximately 1,200 new entries, bringing to nearly 21,000 the number of North Carolina cities, towns, crossroads, waterways, mountains, and other places identified here. The stories attached to place names are at the core of the book and the reason why it has stood the test of time. Some recall faraway places: Bombay, Shanghai, Moscow, Berlin. Others paint the locality as a little piece of heaven on earth: Bliss, Splendor, Sweet Home. In many cases the name derivations are unusual, sometimes wildly so: Cat Square, Huggins Hell, Tater Hill, Whynot. Telling us much about our own history in these snapshot histories of particular locales, The North Carolina Gazetteer provides an engaging, authoritative, and fully updated reference to place names from all corners of the Tar Heel State.
Critical situations in acute and emergency care are one of the great clinical challenges because of the uncertainty, high stakes, time pressure, and stress that are involved. This book provides a comprehensive outline of all the human factors issues relevant to patient safety during acute care. Following an initial section discussing the basic principles of human behavior and decision making, the various influences on safe patient care are discussed in depth. These are divided into three interacting groups: individual factors, team factors, and organizational factors. Relevant psychological theories are carefully examined, and case studies and descriptions of proven strategies help to ground these theories in daily practice. This newly revised edition, in which each chapter has been enlarged and updated, will help both physicians and non-physicians to better understand the principles of human behavior and decision making in critical situations and thus to provide safer treatment.
The definitive guide to the clinical and scientific aspects of pulmonary medicine―fully updated with the latest advances in the field A Doody's Core Title for 2023! Fishman’s Pulmonary Diseases and Disorders delivers unparalleled coverage of pulmonary medicine. With nearly 2500 illustrations, 60 videos, and 22,000 references, this peerless, two-volume resource provides a comprehensive overview of the scientific basis of lung function in health and disease. You’ll find detailed coverage of the broad array of disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms, respiratory infections, and respiratory failure. In addition, you’ll learn about all the latest advances, including molecular development of the lung, stem cells and respiratory disease, the genetics of pulmonary disease, the growth of personalized medicine, technical advances in lung transplantation, and much more. Notable new content in the 6th edition includes discussion of the respiratory effects of vaping, detailed consideration of the idiopathic interstitial pneumonitides, state-of the-art discussion of lung nodules, a summary of the use of immunotherapy in the treatment of lung cancer, COVID-19-related lung disease and its management, and a comprehensive discussion of noninvasive ventilation, including its use in ambulatory and ICU settings. In addition, new chapters on cystic lung disease, lung cancer screening, the lung microbiome, developmental lung disorders, nocardiosis and actinomycosis, and application of ECMO are included.
This book is a companion to “Natural Gas Hydrate in Oceanic and Permafrost Environments” (Max, 2000, 2003), which is the first book on gas hydrate in this series. Although other gases can naturally form clathrate hydrates (referred to after as ‘hydrate’), we are concerned here only with hydrocarbon gases that form hydrates. The most important of these natural gases is methane. Whereas the first book is a general introduction to the subject of natural gas hydrate, this book focuses on the geology and geochemical controls of gas hydrate development and on gas extraction from naturally occurring hydrocarbon hydrates. This is the first broad treatment of gas hydrate as a natural resource within an economic geological framework. This book is written mainly to stand alone for brevity and to minimize duplication. Information in Max (2000; 2003) should also be consulted for completeness. Hydrate is a type of clathrate (Sloan, 1998) that is formed from a cage structure of water molecules in which gas molecules occupying void sites within the cages stabilize the structure through van der Waals or hydrogen bonding.
Discusses three major classes of asthma therapies-bronchodilators, antiinflammatories, and antiallergics-as well as potential new therapeutic approaches! This comprehensive volume addresses the latest treatment strategies for asthma, keying in on the genetics and molecular biology of asthma and pointing the way toward new, commercially viable therapies. Presents the most up-to-date information available on the genetics, epidemiology, pathology, pharmacology, and pulmonology of asthma. Written by more than 20 leading international experts, New and Exploratory Therapeutic Agents for Asthma explores asthma both as incidence of dysfunctional airway smooth muscle and as a disorder of the immune system examines the role of monoclonal antibodies in allergy and asthma describes functions and pharmacokinetic profiles of bronchodilator 2 agonists, anticholinergics, and inhaled glucocorticosteroids investigates the controversy of different types of asthma illustrates the connections between clinical symptoms and the immunopathology of eosinophilic inflammation assesses prospects for the development of a successful oral anti-inflammatory therapy, an immunomodulator that lowers antigen-specific IgE, an anticytokine compound, and an agent that safely combines bronchospasmolytic and anti-inflammatory properties reviews the impact of the recent introduction of antileukotriene agents, clinical findings with PAF antagonists, and selective antimuscarinics evaluates the relationship between improvements in laboratory results and clinical effectiveness and more! Containing over 2000 bibliographic citations and a concise introduction for each chapter, New and Exploratory Therapeutic Agents for Asthma is indispensable for pulmonologists, pediatricians, physiologists, immunologists, allergists, pharmaceutical industry scientists, primary care physicians, and medical school students in these disciplines.
On July 24, 1847, a band of Mormon pioneers descended into the Salt Lake Valley. Having crossed the Great Plains and hauled their wagons over the Rocky Mountains, they believed that their long search for a permanent home had finally come to an end. The valley was an arid and inhospitable place, but to them it was Zion. They settled on the edge of an immense, uncharted, and self-contained region covering over 220,000 square miles, or one-fifteenth of the area of the United States. The early-nineteenth-century explorer John Charles Fremont had just aptly named this region the Great Basin because its lakes and rivers have no outlet to the sea: its waters course down the mountains and disappear into the desert. Here, in a land that few others wanted, the Mormons hoped to live and worship in peace. Within ten years of their arrival, the Mormons had established nineteen communities, extending all the way to San Diego, California--a remarkable feat of colonization and one of the great successes of the westward movement. Desert Between the Mountains is by no means, however, a story of splendid and stoic isolation. Beginning with an explanation of the Great Basin's unique and enigmatic topography, Michael S. Durham delineates the region as a crucible for a complex and exciting narrative history. Tales of nomadic Indian tribes, Spanish ecclesiastics, intrepid furtrappers, and adventurous early explorers are brilliantly and thoroughly chronicled. Moreover, Durham depicts the Mormon way of life under the constant strain from its interaction with miners, soldiers, mountain men, the Pony Express, railroad builders, federal officials, and an assortment of other so-called Gentiles. Durham vigorously explores the dynamics of this important chapter of American history, capturing its epic sweep, its near biblical mayhem, and its unforgettable characters in an illuminating and provocative account. Desert Between the Mountains concludes with the joining of the transcontinental railroad at Promontory, Utah, in 1869, an event that marked the end of the pioneer era. This is a dramatic, multifaceted, and definitive study of the Great Basin, demonstrating, for the first time, that it is a region unified in its history as well as its geography--that today includes all of Nevada, most of Utah, and parts of five other surrounding states.
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