A novel perspective on the biological mechanisms of episodic memory, focusing on the encoding and retrieval of spatiotemporal trajectories. Episodic memory proves essential for daily function, allowing us to remember where we parked the car, what time we walked the dog, or what a friend said earlier. In How We Remember, Michael Hasselmo draws on recent developments in neuroscience to present a new model describing the brain mechanisms for encoding and remembering such events as spatiotemporal trajectories. He reviews physiological breakthroughs on the regions implicated in episodic memory, including the discovery of grid cells, the cellular mechanisms of persistent spiking and resonant frequency, and the topographic coding of space and time. These discoveries inspire a theory for understanding the encoding and retrieval of episodic memory not just as discrete snapshots but as a dynamic replay of spatiotemporal trajectories, allowing us to "retrace our steps" to recover a memory. In the main text of the book, he presents the model in narrative form, accessible to scholars and advanced undergraduates in many fields. In the appendix, he presents the material in a more quantitative style, providing mathematical descriptions appropriate for advanced undergraduates and graduate students in neuroscience or engineering.
Northwestern Ontario is a little-known region that has been central to Canada's prosperity. For many Canadians, the majestic landscape north of Lake Superior conjures up images of tourism, bears, and canoes. For others, it conjures up the phrase "hewers of wood and drawers of water." For almost everyone but its inhabitants, it represents a mythical notion of Canada that never truly existed in the past and certainly does not exist today. In North of Superior, Michel Beaulieu and Chris Southcott explore the region's colourful history from the period before European contact through to the present. Along the way, they tell the stories of the native peoples who first lived there; the traders and adventurers who shaped the region through the Hudson's Bay Company and the North West Company; the politicians and workers who pushed through the CPR; the lumberjacks and miners who profited during the region's golden age; and the vibrant and diverse communities who make their home there today. Northwestern Ontario has always symbolized wealth and adventure for Canadians. This fascinating popular history will interest anyone who wants to know more about a region that occupies an iconic place in Canada's past.
The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.
Athletic and Orthopedic Injury Assessment: Case Responses and Interpretations is a companion book that provides responses and interpretations to the case studies in Athletic and Orthopedic Injury Assessment: A Case Study Approach. Research, evidence-based practices, and professional experience form the basis of these responses and interpretations. The suggested answers for case questions include information such as identification of differential and clinical diagnoses, explanations of diagnostic tests, relevant anatomical information, and more. We hope you find this book helpful in responding to the case questions, whether you are an instructor leading class discussions and analyzing student work, a preprofessional preparing to interpret the case scenarios on the BOC national certification examination, or a student seeking to compare the suggested answers with your own analyses.
Pike's Portage/Death Wins in the Arctic/Arctic Naturalist/Arctic Obsession/Arctic Twilight/Arctic Front/Canoeing North Into the Unknown/Arctic Revolution/In the Shadow of the Pole/Voices From the Odeyak
Pike's Portage/Death Wins in the Arctic/Arctic Naturalist/Arctic Obsession/Arctic Twilight/Arctic Front/Canoeing North Into the Unknown/Arctic Revolution/In the Shadow of the Pole/Voices From the Odeyak
This special bundle is your essential guide to all things concerning Canada’s polar regions, which make up the majority of Canada’s territory but are places most of us will never visit. The Arctic has played a key role in Canada’s history and in the history of the indigenous peoples of this land, and the area will only become more strategically and economically important in the future. This bundle provides an in-depth crash course, including titles on Arctic exploration (Arctic Obsession), Native issues (Arctic Twilight), sovereignty (In the Shadow of the Pole), adventure and survival (Death Wins in the Arctic), and military issues (Arctic Front). Let this collection be your guide to the far reaches of this country. Arctic Front Arctic Naturalist Arctic Obsession Arctic Revolution Arctic Twilight Death Wins in the Arctic In the Shadow of the Pole Pike’s Portage Voices From the Odeyak
With the discovery of planets beyond our solar system 25 years ago, exoplanet research has expanded dramatically, with new state-of-the-art ground-based and space-based missions dedicated to their discovery and characterisation. With more than 3,500 exoplanets now known, the complexity of the discovery techniques, observations and physical characterisation have grown exponentially. This Handbook ties all these avenues of research together across a broad range of exoplanet science. Planet formation, exoplanet interiors and atmospheres, and habitability are discussed, providing in-depth coverage of our knowledge to date. Comprehensively updated from the first edition, it includes instrumental and observational developments, in-depth treatment of the new Kepler mission results and hot Jupiter atmospheric studies, and major updates on models of exoplanet formation. With extensive references to the research literature and appendices covering all individual exoplanet discoveries, it is a valuable reference to this exciting field for both incoming and established researchers.
This book examines the history, culture, and science behind health myths. The word “myth” can have two quite different meanings: (1) a shared tradition or story and (2) a belief that can be falsified. Most previous books have focused on “busting” the second type of myth – explaining why the myth is false. In contrast, “Believe It or Not: The History, Culture, and Science Behind Health Beliefs and Practices” explores the cultural and religious origins of each belief or practice and how it varies among countries and, within countries, according to age, education, ethnicity, and urban vs rural location. Most importantly, the book relies on systematic reviews and meta-analyses to assess the extent to which the health beliefs and practices are true and influence health status. Previous “myth-busting” books have not attempted rigorous, systematic evaluations of the scientific evidence for and against the beliefs and practices they discuss. This book includes a range of chapters dedicated to infection, skin and eye conditions, diet and food, and pregnancy and childbirth. In an era when social media, fake news, and contradictory opinions are a mere click away, people deserve to understand the science underlying common health beliefs. Believe It or Not: The History, Culture, and Science Behind Health Beliefs and Practices is a valuable read for the general public, curious about health and science but without technical, scientific, or medical training.
Travel narratives were the principal source of knowledge about the lands of the Near East and the Indian Ocean Basin in 17th-century France. Claiming the authority of first-hand observation, they paradoxically rely for their legitimization on the tropes of an established literary tradition. The status of these texts remained ambiguous, not least because of their anecdotal depictions of great riches, brutality or sexual promise. Drawing on the insights of post-colonial scholarship, this study tackles a question given scant attention in previous work and suggests that beyond the hazy representation of the Orient, an opposition emerges between the threatening Near East and the indolent East Indies. Distinguishing recognizable representations from those generated by new encounters, this book questions the feasibility of cultural representation through travel, exploring a large corpus of original sources written by French ecclesiastics, gentlemen-travellers, ambassadors and adventurers. Linguistic, religious, cultural or geographical barriers meant most travellers remained distanced from the peoples about whom they would simultaneously become authoritative. The encounter was further transformed in narratives that were intended to entertain and to satisfy the criterion of curiosité. The ‘Oriental’ that emerges is a supremely variable entity, alternately naked or veiled, barbaric or civilized, menacing or attractive.
In the mid-first millennium B.C., the Eanna temple at Uruk sacrificed a minimum of nine lambs every day in its basic routine of offerings to its gods; in addition to these, special occasions and festivals demanded the sacrifice of as many as 90 lambs in a single day. All told, the Eanna sacrificed about 4,300 lambs per year. There were more than 120 herdsmen connected to the Eanna at any given time, and the temple expected there to be tens of thousands of sheep and goats under their responsibility. These herdsmen delivered male lambs to the Eanna for sacrifice, and the temple had an internal infrastructure for the care, maintenance, and ritual expenditure of these lambs; they also delivered wool, which the Eanna sold mostly in bulk quantities. This book aims to analyze the economic organization of this entire system of sheep and goat maintenance and utilization, to explore the economic and social relationships between the Eanna and its herdsmen, and to integrate the study of the Eanna’s animal economy into the developing picture of the Neo-Babylonian temple economy as a whole. Kozuh’s careful examination of the bookkeeping records, the management records, and legal documents connected with this substantial enterprise sheds new light on an arcane area of first-millennium Mesopotamian life that will be sure to enlighten our understanding of the daily life, economy, and social structure of this region.
George III was one of the longest reigning British monarchs, ruling over most of the English speaking world from 1760 to 1820. Despite his longevity, George’s reign was one of turmoil. Britain lost its colonies in the War of American Independence and the European political system changed dramatically in the wake of the French Revolution. Closer to home, problems with the King’s health led to a constitutional crisis. Charlotte Papendiek’s memoirs cover the first thirty years of George III’s reign, while Mary Delany’s letters provide a vivid portrait of her years at Windsor. Lucy Kennedy was another long-serving member of court whose previously unpublished diary provides a great deal of new detail about the King’s illness. Finally, the Queen herself provides further insights in the only two extant volumes of her diaries, published here for the first time. The edition will be invaluable to scholars of Georgian England as well as those researching the French and American Revolutions and the history and politics of the Regency period more widely.
What is the future of food in light of growing threats from the climate emergency and natural resource depletion, as well as economic and social inequality? This textbook engages with this question, and considers the complex relationships between food, place, and space, providing students with an introduction to the contemporary and future geographies of food and the powerful role that food plays in our everyday lives. Geographies of Food explores contemporary food issues and crises in all their dimensions, as well as the many solutions currently being proposed. Drawing on global case studies from the Majority and Minority Worlds, it analyses the complex relationships operating between people and processes at a range of geographical scales, from the shopping decisions of consumers in a British or US supermarket, to food insecurity in Sub-Saharan Africa, to the high-level political negotiations at the World Trade Organization and the strategies of giant American and European agri-businesses whose activities span several continents. With over 60 color images and a range of lively pedagogical features, Geographies of Food is essential reading for undergraduates studying food and geography.
A Doody's Core Title for 2023! The #1 Textbook in Pharmacotherapy providing optimal patient outcomes using evidence-based medication therapies—updated with the latest advances and guidelines For more than 30 years, DiPiro’s Pharmacotherapy has been the essential textbook for learning how to properly select, administer, and monitor drugs―everything needed to provide safe, effective drug therapy across all therapeutic categories. This new edition has been fully updated with the latest evidence-based information and recommendations. With content from 300 expert contributors, this valuable resource offers detailed descriptions of common and uncommon disease states, including treatment by pharmacologic and non-pharmacologic means. Each disease chapter opens with a Patient Care Process, helping readers understand the collaborative care model in which pharmacists work and communicate with other healthcare providers for effective coordinated care. Here's why DiPiro's Pharmacotherapy: A Pathophysiologic Approach is the perfect learning tool for students, pharmacists, and other healthcare providers: All chapters provide the most current, reliable, and relevant information available Key concepts are included at the beginning of each chapter Clinical Presentation boxes concisely outline disease signs and symptoms New: Beyond the Book feature points readers to multimedia resources to deepen their understanding of the material Diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches clearly distinguish treatment pathways New: Drug monitoring tables have been added Patient care process boxes help readers know how to communicate with other health care providers New: Additional FREE E-Chapters are available on AccessPharmacy New: Over 2000 Review Questions to help prepare students!
Offers analysis and design considerations for the presentation of complex and technical information on Web sites, using a theory that deals with highly complex issues and user goals. For scholars, researchers, and students in technical communication, inf
This thoroughly updated edition of the bestselling Psychology for A2 Level has been written specifically for the new AQA-A Psychology A2-level specification for teaching from September 2009. It is the ideal follow-up to AS Level Psychology, 4th edition by the same author, but also to any AS-level textbook. This full-colour book, which builds on the ideas and insights explored at AS Level to promote a deeper understanding of psychology, is written in an engaging and accessible style by a highly experienced author. It incorporates contributions, advice and feedback from a host of A-Level teachers and psychologists including Philip Banyard, Evie Bentley, Clare Charles, Diana Dwyer, Mark Griffiths and Craig Roberts. At this level, students select options from a range of specified topics and this book includes chapters on all of the compulsory and optional topics that are on the new A2 syllabus in sufficient depth for the requirements of the course. It has a new focus on the nature and scope of psychology as a science with an emphasis on how science works, and guidance on how to engage students in practical scientific research activities. Presented in a clear, reader-friendly layout, the book is packed with advice on exam technique, hints and tips to give students the best chance possible of achieving the highest grade. The book is supported by our comprehensive package of online student and teacher resources, A2 Psychology Online. Student resources feature a wealth of multimedia materials to bring the subject to life, including our new A2 revision guide and A2 Workbook, multiple choice quizzes, revision question tips, interactive exercises and podcasts by key figures in psychology. Teacher resources include a teaching plan, chapter-by-chapter lecture presentations, and classroom exercises and activities.
In this comprehensive social history of the Bon Marché, the Parisian department store that was the largest in the world before 1914, Michael Miller explores the bourgeois identities, ambitions, and anxieties that the new emporia so vividly dramatized. Through an original interpretation of paternalism, public images, and family-firm relationships, he shows how this new business enterprise succeeded in reconciling traditional values with the coming of an age of mass consumption and bureaucracy.
This comprehensive text critically examines the experience of older people, from western and non-western cultures, as both victims and perpetrators of crime. An argument is presented emphasising issues of human rights and free will.
Offering a state-of-the-art, authoritative summary of the most relevant scientific and clinical advances in the field, Principles and Practice of Movement Disorders provides the expert guidance you need to diagnose and manage the full range of these challenging conditions. Superb summary tables, a large video library, and a new, easy-to-navigate format help you find information quickly and apply it in your practice. Based on the authors' popular Aspen Course of Movement Disorders in conjunction with the International Parkinson and Movement Disorder Society, this 3rd Edition is an indispensable resource for movement disorder specialists, general neurologists, and neurology residents. - Explores all facets of movement disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. - Provides the essential information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. - Reflects recent advances in areas such as the genetics of Parkinsonian and other movement disorders, diagnostic brain imaging, new surgical approaches to patients with movement disorders, and new treatment guidelines for conditions such as restless legs syndrome. - Features a reader-friendly, full-color format, with plentiful diagrams, photographs, and tables. - Includes access to several hundred updated, professional-quality video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses.
50th Anniversary Edition of the groundbreaking case-based pharmacotherapy text, now a convenient two-volume set. Celebrating 50 years of excellence, Applied Therapeutics, 12th Edition, features contributions from more than 200 experienced clinicians. This acclaimed case-based approach promotes mastery and application of the fundamentals of drug therapeutics, guiding users from General Principles to specific disease coverage with accompanying problem-solving techniques that help users devise effective evidence-based drug treatment plans. Now in full color, the 12th Edition has been thoroughly updated throughout to reflect the ever-changing spectrum of drug knowledge and therapeutic approaches. New chapters ensure contemporary relevance and up-to-date IPE case studies train users to think like clinicians and confidently prepare for practice.
In 1988 the philosopher Gilles Deleuze remarked that, throughout his career, he had always been 'circling around' a concept of nature. Providing critical analysis of his highly original readings of Stoicism, Aristotle, and Epicurus, this book shows that it is Deleuze's interpretations of ancient Greek physics that provide the key to understanding his conception of nature. Using the works of Aristotle, Plato, Chrysippus, and Epicurus, Michael Bennett traces the development of Deleuze's key concepts of event, difference, and problem. Arguing that it is difficult, if not impossible, to fully understand these ideas without an appreciation of Deleuze's Hellenistic influences, Deleuze and Ancient Greek Physics situates his commentaries in the context of contemporary scholarship on ancient Greek philosophy. Delving into the original Greek and Latin texts, this book shows that Deleuze's readings are more complex and controversial than they first appear, simultaneously advancing Deleuze as a new voice in interpretations of ancient Greek philosophy. Generating both new critical analyses of Deleuze and a new appreciation for his classical erudition, Deleuze and Ancient Greek Physics will be a valuable resource for anyone interested in ancient Greek philosophy, Deleuze's philosophical project or his unique methodology in the history of philosophy.
The Interventional Radiology volume of the landmark reference Abrams' Angiography has now been expanded and thoroughly revised to reflect dynamic advances in interventional radiology. More than 60 contributors representing a "Who's Who" of the specialty provide comprehensive, step-by-step coverage of all contemporary vascular and nonvascular interventional procedures. Major sections discuss today's equipment and describe interventions for specific disorders of each organ system, as well as for trauma, pediatric diseases, abscess drainage, and miscellaneous disorders. More than 1,100 illustrations complement the text. This edition incorporates an extensive new section on interventional oncologic procedures. The section covers all organ-specific cancers for which interventional therapies are used. Other sections include artervenous malformations, liver diseases, arterial occlusive disease, aneurysms, traumatic arterial injuries, hemorrhage, and venous diseases. It also has full color.
This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors. Although there have been many symposia on this topic, and numerous publications of reviews dealing with selected subsets of growth factors, the entire field has never been covered in a single treatise. It is essential to do this at the present time, as the number of journal articles on peptide growth factors now makes it almost impossible for anyone person to stay informed on this subject by reading the primary literature. At the same time it is becoming increasingly apparent that these substances are of universal importance in biology and medicine and that the original classification of these molecules, based on the laboratory setting of their discovery, as "growth factors," "lymphokines," "cytokines," or "colony stimulating factors," was quite artifactual; they are in fact the basis of a com mon language for intercellular communication. As a set they affect essentially every cell in the body, and in this regard they provide the basis to develop a unified science of cell biology, germane to all of biomedical research. This treatise is divided into four main sections. After three introductory chapters, its principal focus is the detailed description of each of the major peptide growth factors in 26 individual chapters.
The new edition of the highly respected Researching Communications is a comprehensive and authoritative guide to researching media and communication. Researching Communications, Third Edition is an invaluable guide to performing and analysing research tasks, introducing the major research methods, giving detailed examples of research analysis and practical step-by-step guidance in clear language. Written by highly regarded experts in the field, the third edition includes new sections on social media analysis, digital research methods and comparative research, as well as updated case studies, international examples and details of recent developments in media and communication studies. Undergraduate and postgraduate media and communication students will find Researching Communications an invaluable resource at all stages of their course.
Why did the last of the major European campaigns to reclaim Jerusalem end in an attack on Tunis, a peaceful North African port city thousands of miles from the Holy Land? In the first book-length study of the campaign in English, Michael Lower tells the story of how the classic era of crusading came to such an unexpected end. Unfolding against a backdrop of conflict and collaboration that extended from England to Inner Asia, the Tunis Crusade entangled people from every corner of the Mediterranean world. Within this expansive geographical playing field, the ambitions of four powerful Mediterranean dynasts would collide. While the slave-boy-turned-sultan Baybars of Egypt and the saint-king Louis IX of France waged a bitter battle for Syria, al-Mustansir of Tunis and Louis's younger brother Charles of Anjou struggled for control of the Sicilian Straits. When the conflicts over Syria and Sicily became intertwined in the late 1260s, the Tunis Crusade was the shocking result. While the history of the crusades is often told only from the crusaders' perspective, in The Tunis Crusade of 1270, Lower brings Arabic and European-language sources together to offer a panoramic view of these complex multilateral conflicts. Standing at the intersection of two established bodies of scholarship - European History and Near Eastern Studies - this volume contributes to both by opening up a new conversation about the place of crusading in medieval Mediterranean culture.
This comprehensive reference guide reviews the literature concerning the impact of the automobile on American social, economic, and political history. Covering the complete history of the automobile to date, twelve chapters of bibliographic essays describe the important works in a series of related topics and provide broad thematic contexts. This work includes general histories of the automobile, the industry it spawned and labor-management relations, as well as biographies of famous automotive personalities. Focusing on books concerned with various social aspects, chapters discuss such issues as the car's influence on family life, youth, women, the elderly, minorities, literature, and leisure and recreation. Berger has also included works that investigate the government's role in aiding and regulating the automobile, with sections on roads and highways, safety, and pollution. The guide concludes with an overview of reference works and periodicals in the field and a description of selected research collections. The Automobile in American History and Culture provides a resource with which to examine the entire field and its structure. Popular culture scholars and enthusiasts involved in automotive research will appreciate the extensive scope of this reference. Cross-referenced throughout, it will serve as a valuable research tool.
. . . a major contribution to cornett research and belongs in the library of every cornettist." —Historic Brass Society ". . . scrupulously detailed. . . The first successful attempt to provide a comprehensive reference book on the cornett and its music. Recommended for both upper-division undergraduate libraries and collections serving music scholars and performers." —Choice " . . . it will likely stand as the definitive bibliography of cornett music for many years." —Notes ". . . this is a groundbreaking study of the subject . . . likely to remain the only major study of the instrument and the music composed for it." —American Reference Books Annual ". . . every cornett player owes an immense debt of gratitude to [the authors and their assistants] for revealing such a wealth of performing opportunities . . ." —European Journal of Early Music The cornett is made of wood but has a brass cup mouthpiece and uses woodwind finger technique. Here the authors have compiled a bibliography of all extant sources of instrumental and vocal music which specify the cornett.
Many scientists find themselves working in the laboratory without sufficient background in current biotechnology methods. Others want to keep up with the revolution in biotechnology and the flood of new methodologies. This book provides a solution for both: a multidisciplinary approach to the methods essential to biotechnical development. C
Elsevier’s new Problem Solving in Abdominal Imaging offers you a concise, practical, and instructional approach to your most common imaging questions. It presents basic principles of problem solving to apply to imaging the abdominal and pelvic organs, gastrointestinal tract, and genitourinary tract. Inside, you’ll find expert guidance on how to accurately read what you see, and how to perform critical techniques including biopsy and percutaneous drainage. User-friendly features, such as tables and boxes, tips, pitfalls, and rules of thumb, place today’s best practices at your fingertips. A full-color design, including more than 700 high-quality images, highlights critical elements and compliments the text, to enhance your understanding. Provides problem-solving advice to help you find abnormalities and accurately identify what you see. Presents a section devoted to clinical scenarios—organized by presenting signs or disease processes—covering those you’re most likely to encounter in daily practice. Includes tips for optimization of the most common advanced imaging techniques used for the abdominal and pelvic regions—with general indications for use and special situations—to help you make the most of each modality. Offers step-by-step guidance that will help you safely approach challenging abdominal interventions, reduce complications, and improve outcomes. Features tables and boxes, tips, pitfalls, and other teaching points for easy reference. Incorporates high-quality images and a full-color design that illuminate important elements.
The fourth edition of Michael Yapko's classic text, Trancework, continues to be the comprehensive guide for learning the fundamental skills of clinical hypnosis. This new edition not only accommodates new studies and topics that have attained a level of importance worthy of their inclusion, but also contains five new chapters on topics such as mind-body therapy, positive psychology, and pediatric hypnosis"--
Nanotechnology: The Future is Tiny introduces over a hundrerd specific research projects that are currently being investigated in laboratories distributed throughout the world.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
Emerging Nanomedicines for Diabetes Mellitus Theranostics provides readers with information on the development of efficacious nanomedicines as potential theranostic agents for diabetes. The book discusses the application of various novel nanomaterials and nanocomposites for targeted delivery of insulin, glucose sensing, including nano-tattoos as glucose monitors, biosynthesized nanoparticles for diabetes treatment, and pre-clinical and clinical assays to evaluate the efficacy of nanomedicines for diabetes treatment. This is an important references source for materials scientists, pharmaceutical scientists and biomedical engineers who want to increase their understanding of how nanotechnology is being used to improve diabetes treatment. Diabetes has emerged as one of the most common diseases associated with lifestyle choices in the modern world, with significant mortality rates. Conventional treatment methods mainly involve insulin-based therapies. However, insulin therapy possesses several limitations such as weight gain and hypoglycemia. Thus, advanced research in nanomedicine is targeting the development of new and improved diagnostics and treatment methods for diabetes. - Explores the significance of nanomaterials and nanocomposites for the controlled delivery of insulin and effective diagnosis of diabetes - Assesses the efficacy of novel nano-tattoos as an emerging glucose monitoring system and the potential of biosynthesized nanoparticles as pharmaceutical ingredients for diabetes treatment - Describes various pre-clinical and clinical assays to evaluate the toxicity of nanomedicines, along with methods to mitigate the challenges associated with effective diabetes therapy via the use of nanorobots, nanoformulations and smartphone-based technologies
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