Perry’s The Chemotherapy Source Book, now in its fifth edition, provides information on the choice of chemotherapeutic agents, the use of combination chemotherapy, and the toxicity of individual drugs. Organized by site, this is the only book of its kind to focus strictly on the clinical practice of chemotherapy, and is meant to serve as a “one-stop shop” for information on choice of chemotherapeutic agents, treatment outlines, grading of side effects, and dose modification.
The ultimate survival guide for bewildered husbands-to-be covers everything grooms need to know about legal issues, selecting a best man and ushers, donning a tuxedo, planning a honeymoon, choosing a first home, and adjusting to marital life.
Tyler Perry has been writing plays since the age of eighteen. His popular Madea franchise has grossed over 450 billion dollars worldwide. This informative biography discusses the life of actor, playwright, screenwriter, theater director, film director, television director, film producer, and television producer Tyler Perry. Chapters cover his early years, life in New Orleans, Louisiana, and the evolution of the Tyler Perry Studios in Atlanta, Georgia.
Prior to the Nixon administration, environmental policy in the United States was rudimentary at best. Since then, it has evolved into one of the primary concerns of governmental policy from the federal to the local level. As scientific expertise on the environment rapidly developed, Americans became more aware of the growing environmental crisis that surrounded them. Practical solutions for mitigating various aspects of the crisis - air pollution, water pollution, chemical waste dumping, strip mining, and later global warming - became politically popular, and the government responded by gradually erecting a vast regulatory apparatus to address the issue. Today, politicians regard environmental policy as one of the most pressing issues they face. The Obama administration has identified the renewable energy sector as a key driver of economic growth, and Congress is in the process of passing a bill to reduce global warming that will be one of the most important environmental policy acts in decades. The Oxford Handbook of U.S. Environmental Policy is a state-of-the-art work on all aspects of environmental policy in America. Over the past half century, America has been the world's leading emitter of global warming gases. However, environmental policy is not simply a national issue. It is a global issue, and the explosive growth of Asian countries like China and India mean that policy will have to be coordinated at the international level. The book therefore focuses not only on the U.S., but on the increasing importance of global policies and issues on American regulatory efforts. This is a topic that will only grow in importance in the coming years, and this handbook serves as an authoritative guide to any scholar interested in the issue.
Knowledge and Communities is the first book dedicated to a major new knowledge management topic. "Communities of Practice" are cross-organizational groups of people sharing knowledge, solving common problems, and exchanging insights and frustrations. Knowledge and Communities, a collection of authoritative articles, describes the dynamics of these groups and explains how they enable organizational knowledge to be creating, shared, and applied. The book teaches how organizations can empower both traditional and on-line communities and make them a cornerstone of a general knowledge management strategy. Readers will learn how communities can help unify an organization and its external stakeholders, such as customers and suppliers, and how they can critically support an e-commerce strategy. Knowledge and Communities will help readers understand a primary vehicle for building an organization's social capital and competitive advantage.
Biotechnology represents a major area of research focus, and many universities are developing academic programs in the field. This guide to biomanufacturing contains carefully selected articles from Wiley's Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology as well as new articles (80 in all,) and features the same breadth and quality of coverage and clarity of presentation found in the original. For instructors, advanced students, and those involved in regulatory compliance, this two-volume desk reference offers an accessible and comprehensive resource.
Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.
In this book, Michael Keith argues that both racial divisions and intercultural dialogue can only be understood in the context of the urban cities that gave them birth, and considers how race is played out in the worlds most eminent cities.
Jesse Dukeminier’s trademark wit, passion, and human interest perspective has made Property, now in its Ninth Edition, one of the best—and best loved—casebooks of all time. A unique blend of authority and good humor, you’ll find a rich visual design, compelling cases, and timely coverage of contemporary issues. In the Ninth Edition, the authors have created a thoughtful and thorough revision, true to the spirit of the classic Property text. Key Benefits: A new chapter on the Intellectual Property/Property relationship, that gives students a taste of patent law, copyright law, trademark law, and trade secrets law. The chapter highlights the differences and similarities among the legal treatment of real, chattel, and intellectual property. A dynamic, two-color designed casebook that encompasses cases, text, questions, problems, examples and numerous photographs and diagrams. Extended coverage of major recent Supreme Court decisions, including Murr v. Wisconsin, Horne v. Department of Agriculture, and Marvin M. Brandt Revocable Trust v. United States.
Two excellent resource books are combined to form a single comprehensive database that offers summaries of environmental properties The Agrochemicals and Pesticides Desk Reference on CD-ROM contains specific information about 137 pesticides, serving as a primer of environmental toxicology and an extensive trade name index. Profiles of each pesticide provide regulatory information toxicity assessments environmental fate data physical properties acceptable exposure limit values This CD-ROM is an up-to-date reference inspired by the growing number of research publications and the continued interest in the fate, transport, and remediation of hazardous substances. Featured are environmental and physical/chemical data on more than 300 compounds, including pesticides, herbicides, and fungicides.
Muhammad ibn ‘Abd al-Wahhab (1703-1792) aroused great controversy in his lifetime. More than two centuries after his death he still elicits strong views. For some he is the model of a pious religious activist who fought to establish a regime of Islamic godliness in the least promising of environments. For others, especially Muslims associated with mystic orders or who belong to the Shi‘i branch of Islam, he is a hate figure. Few would contest that he shaped the Muslim world. For over two hundred and fifty years the Wahhabi religious movement has rested on the twin pillars of a clear, compelling credo and an indissoluble alliance with temporal power in Arabia. Absolutist, uncompromising theology and political and religious ambition combined to make it the dominant force there, turning its champions, the Al Sa‘ud clan, from petty rulers of a middle-sized settlement with a talent for balancing interests, into the guardians of Islam’s Holy Places, disposing of the earth’s greatest identified oil reserves. This thought-provoking and incisive biography, which charts the relationship between religious doctrine, political power and events on the ground, is ideal for readers interested in uncovering the life and convictions of the man who founded the Wahhabi movement and a dynastic alliance between his clerical descendants and Saudi princes that has lasted to the present day.
This fully revised fourth edition of a well-respected textbook seeks to build social workers' confidence in legal interpretation and implementation - practitioners must not only know the law; they must also have a critical appreciation of its implications for human rights, civil liberties and social justice. With a focus on promoting knowledge and skills in recognising, locating and articulating legal issues, it also demonstrates how the law can be used to inform practice standards and deliver positive outcomes for service users. This is essential reading for social work law modules at undergraduate and postgraduate level. Practitioners and educators will also find it an invaluable resource to guide them through a complex, yet vital, aspect of their work.“br/> New to this Edition: - Combines up-to-date statute, case law and guidance with extended practice examples and questions for reflection
Technology plays a crucial role in contemporary mathematics education. Teaching Secondary Mathematics covers major contemporary issues in mathematics education, as well as how to teach key mathematics concepts from the Australian Curriculum: Mathematics. It integrates digital resources via Cambridge HOTmaths (www.hotmaths.com.au), a popular, award-winning online tool with engaging multimedia that helps students and teachers learn and teach mathematical concepts. This book comes with a free twelve-month subscription to Cambridge HOTmaths. Each chapter is written by an expert in the field, and features learning outcomes, definitions of key terms and classroom activities - including HOTmaths activities and reflective questions. Teaching Secondary Mathematics is a valuable resource for pre-service teachers who wish to integrate contemporary technology into teaching key mathematical concepts and engage students in the learning of mathematics.
Long hours, low wages, and unsafe workplaces characterized sweatshops a hundred years ago. These same conditions plague American trucking today. Sweatshops on Wheels: Winners and Losers in Trucking Deregulation exposes the dark side of government deregulation in America's interstate trucking industry. In the years since deregulation in 1980, median earnings have dropped 30% and most long-haul truckers earn less than half of pre-regulation wages. Work weeks average more than sixty hours. Today, America's long-haul truckers are working harder and earning less than at any time during the last four decades. Written by a former long-haul trucker who now teaches industrial relations at Wayne State University, Sweatshops on Wheels raises crucial questions about the legacy of trucking deregulation in America and casts provocative new light on the issue of government deregulation in general.
Presents an up-to-date analysis of critical constitutional issues. Special attention is given to issues of greatest concern to criminal justice personnel - detention, arrest, search and seizure, interrogations and confessions, self-incrimination, due process, and right to counsel. Also includes constitutional aspects of criminal and civil liabilities of justice personnel, and constitutional and civil rights in the workplace. Part II presents key cases to assist in interpreting the constitutional provisions. Each chapter includes chapter outline, key terms and concepts, as well as numerous boxes defining terms and elaborating on the text. Part II contains briefs of judicial decisions related to the topics covered in the the text, in order to help the reader learn rule of law as well as the reasoning of the court that guides future court rulings. Part III contains the Constitution of the United States of America, a Glossary and a Table of Cases.
The old buildings and historic places of British Columbia form a kind of "roadside memory," a tangible link with stories of settlement, change, and abandonment that reflect the great themes of BC's history. Michael Kluckner began painting his personal map of the province in a watercolour sketchbook. In 1999, after he put a few of the sketches on his website, a network of correspondents emerged that eventually led him to the family letters, photo albums, and memories from a disappearing era of the province. Vanishing British Columbia is a record of these places and the stories they tell, presenting a compelling argument for stewardship of regional history in the face of urbanization and globalization.
What does the law require of social workers when deciding how to intervene to protect children and adults at risk? What social work standards should guide decisions about whether, when and how to invoke statutory powers and duties in practice? Making Good Decisions provides an accessible and practical guide to the legal rules and principles that should guide everyday social work practice. It sets out the key elements of administrative law, equality and human rights legislation which shape how social workers practise and illustrates how knowledge and use of legal principles can support core social work goals, including empowerment, equality and social justice. An invaluable reference point for all students and practitioners, this book will support and empower social workers to feel more confident in making and challenging decisions, more credible when presenting assessments and plans, and more creative when working with service users and carers. The text is supported by a range of innovative features and boxed information to aid learning and stimulate reflection: - Key Case Analysis boxes summarise the details of particular legal cases and outline the implications for social work practice. - Practice Focus boxes apply legal principles and processes to practice through the use of social work scenarios. - On-The-Spot Questions reinforce understanding and encourage critical reflection.
This Island Trip Is No Vacation -Exhaustive stealth strategy for eight new single-player missions and five new multiplayer maps -Get ahead of the pack with exclusive mission maps revealing all enemy positions -Expert weapon tips for the entire arsenal, including the M4 SOCOM, the SR-25 sniper rifle, and 10 other new multiplayer weapons -Advanced tips for online Xbox "Live"TM play -In-depth fighting tips, including one-shot kills and advice on the real-time orders system -Battle scenarios for all four soldier types -Unlock secret combat specialists -Complete in-depth walkthroughs for each Island Thunder mission
The plant hormone ethylene is one of the most important, being one of the first chemicals to be determined as a naturally-occurring growth regulator and influencer of plant development. It was also the first hormone for which significant evidence was found for the presence of receptors. This important new volume in Annual Plant Reviews is broadly divided into three parts. The first part covers the biosynthesis of ethylene and includes chapters on S-adenosylmethionine and the formation and fate of ACC in plant cells. The second part of the volume covers ethylene signaling, including the perception of ethylene by plant cells, CTR proteins, MAP kinases and EIN2 / EIN3. The final part covers the control by ethylene of cell function and development, including seed development, germination, plant growth, cell separation, fruit ripening, senescent processes, and plant-pathogen interactions. The Plant Hormone Ethylene is an extremely valuable addition to Wiley-Blackwell's Annual Plant Reviews. With contributions from many of the world's leading researchers in ethylene, and edited by Professor Michael McManus of Massey University, this volume will be of great use and interest to a wide range of plant scientists, biochemists and chemists. All universities and research establishments where plant sciences, biochemistry, chemistry, life sciences and agriculture are studied and taught should have access to this important volume.
Medical Management of the Thoracic Surgery Patient, by Michael I. Lewis, MD and Robert J. McKenna, Jr., MD, is a comprehensive pulmonary and thoracic reference that takes a practical approach to the diagnosis, workup and care of the thoracic surgery patient. It is geared towards pulmonary and critical care physicians and their trainees as well as all other specialties with whom thoracic surgeons consult and interact. It outlines the principles for understanding the underlying disease entities as well as the clinical implications and complications of surgery, and interprets key surgical concepts such as correlative and functional anatomy for non-surgeons. Contributions from today’s authorities...“at-a-glance detailed key information, as well as summary bullets...and a multidisciplinary perspective, combine to offer essential guidance for confident patient management. As an Expert Consult title it includes convenient online access to the complete contents of the book—fully searchable—along with video clips of thoracic procedures, patient information sheets, all of the images downloadable for your personal use, and references linked to Medline at www.expertconsult.com. Includes access to a companion website at expertconsult.com where you can search the complete contents of the book, watch video clips of thoracic procedures, print out patient information sheets, download all of the images, and review references linked to Medline...providing you with a powerful resource for convenient consultation anytime, anywhere. Features ‘real world’ illustrative cases presented in a brief, bulleted format that facilitates easy access to and retention of the material. Examines every aspect of diagnosis and management for pre-, peri-, and postoperative care for an all-encompassing reference to respond to unique surgical problems. Provides coverage of individual topics supplemented by a brief case-based presentation, where appropriate, that lend a real-life perspective to the material. Contains all of the “need-to-know facts for a complete, thorough consultation in diagnosis and treatment of patients who undergo thoracic surgery. Offers practical information that utilizes the experience of today’s leaders while based on evidence in the literature for coverage you can trust. Examines current clinical controversies, providing you with an arena for discussion of sensitive topics and guidance on preferred approaches when relevant. Presents pearls, pitfalls, key points, and other learning elements in each chapter, to help you locate summaries of essential information “at-a-glance. Features chapters written by specialists of various disciplines, to equip you with a balanced perspective on each condition.
A Doody's Core Title 2012 This new comprehensive reference provides a state-of-the-art overview of the principles of cancer care and best practices for restoring function and quality of life to cancer survivors. Authored by some of the world« leading cancer rehabilitation experts and oncology specialists, the principles section provides primer level discussions of the various cancer types and their assessment and management. The practice section thoroughly explores the identification, evaluation, and treatment of specific impairments and disabilities that result from cancer and the treatment of cancer.This groundbreaking volume enables the entire medical team to provide superior care that results in a better quality of life for cancer survivors. Features include: Multi-specialty editorship and authorship from physiatry, oncology, physical therapy, occupational therapy,and related disciplines. Focus on therapeutic management of cancer-related impairments and complications. In-depth treatment of the medical, neurologic, musculoskeletal, and general rehabilitation issues specific to this patient population.
Authored by some of the world's leading cancer experts from wide ranging disciplines including oncology, radiation oncology, neurosurgery, orthopedic surgery, and radiology this compact volume provides authoritative state-of-the-art primer level overviews of the various cancer types, their evaluation, and treatment. Every aspect of oncology is covered with clear, up-to-date descriptions of the general principles and concepts fundamental to attaining a clinical appreciation of the foundations of cancer care. Each chapter is concise but highlights the basic tenets health care professionals working with cancer patients need to know to understand the diseases and current treatment options. To facilitate review, Key Points are boxed in each chapter to summarize important clinical information and concepts at a glance. This book represents a synthesis of information from some of the top physicians in oncology that is not as easily accessed anywhere else. Features of Synopsis of Clinical Oncology include: Multi-specialty expert authorship Focus on therapeutics management of cancer Key Points boxed in each chapter for quick review
The first book of its kind to focus on the diagnosis, prevention, and treatment of patients with fungal infections, this definitive reference returns in a completely revised, full-color new edition. It presents specific recommendations for understanding, controlling, and preventing fungal infections based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. More than 560 photographs, illustrations, and tables depict conditions as they appear in real life and equip you to identify clinical manifestations with accuracy. Expanded therapy content helps you implement the most appropriate treatment quickly. Includes specific recommendations for diagnosing, preventing, and treating fungal infections in various patient populations based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. Covers etiologic agents of disease, fungal infections in special hosts such as pediatric patients and patients with cancer and HIV, infections of specific organ systems, and more, to make you aware of the special considerations involved in certain cases. Features clinically useful and reader-friendly practical tools—including algorithms, slides, graphs, pictorials, photographs, and radiographs—that better illustrate and communicate essential points, promote efficient use in a variety of clinical and academic settings, and facilitate slide making for lectures and presentations. Offers more clinically relevant images—more than 300 in full color for the first time—to facilitate diagnosis. Features expanded therapy-related content, including up-to-date treatment strategies and drug selection and dosing guidelines. Includes several new sections in the chapter on fungal infections in cancer patients that reflect the formidable clinical challenges these infections continue to present. Presents the work of additional international contributors who have defined many of the key issues in the field, providing more of a global perspective on the best diagnostic and management approaches. Uses a new, full-color design to enhance readability and ease of access to information.
The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational challenges and opportunities that drug repositioning offers. Readers will learn how to perform the latest experimental and computational methods that support drug repositioning, and detailed case studies throughout the book demonstrate how these methods fit within the context of a comprehensive drug repositioning strategy. Drug Repositioning is divided into three parts: Part 1, Drug Repositioning: Business Case, Strategies, and Operational Considerations, examines the medical and commercial drivers underpinning the quest to reposition existing drugs, guiding readers through the key strategic, technical, operational, and regulatory decisions needed for successful drug repositioning programs. Part 2, Application of Technology Platforms to Uncover New Indications and Repurpose Existing Drugs, sets forth computational-based strategies, tools, and databases that have been designed for repositioning studies, screening approaches, including combinations of existing drugs, and a look at the development of chemically modified analogs of approved agents. Part 3, Academic and Non-Profit Initiatives & the Role of Alliances in the Drug Repositioning Industry, explores current investigations for repositioning drugs to treat rare and neglected diseases, which are frequently overlooked by for-profit pharmaceutical companies due to their lack of commercial return. The book's appendix provides valuable resources for drug repositioning researchers, including information on drug repositioning and reformulation companies, databases, government resources and organizations, regulatory agencies, and drug repositioning initiatives from academia and non-profits. With this book as their guide, students and pharmaceutical researchers can learn how to use drug repositioning techniques to extend the lifespan and applications of existing drugs as well as maximize the return on investment in drug research and development.
The most current scientific information from the world's leading medical journals. Although there is growing consumer awareness of alternative and complementary medicine, there is a lack of comprehensive information available on herbal products. While pharmacists, physicians and other health care professionals sometimes offer advice, their patients want more information. The Complete Natural Medicine Guide to the 50 Most Common Medicinal Herbs is a comprehensive, fully-illustrated reference to the 50 most commonly prescribed herbs. A complete description of each herb is featured along with its other common names, possible adverse effects, therapeutic uses for treating illness and disease as well as potential drug interactions. Some of the herbs included are: Aloe Vera Evening Primrose Goldenseal Scullcap Burdock Tumeric Tea Tree Oil Meadowsweet This guide is written by professional pharmacists, one a naturopathic doctor, using the most current research and clinical testing. The authors' easy-to-understand text, combined with the latest findings and clear directions for safe dosages, makes this practical reference on medicinal herbs a primary resource of data.
The definitive, A-to-Z overview of evidence-based rehab programs using therapeutic exercise In this exceptional evidence-and-guide-based, clinically-oriented resource, you'll learn everything you need to know about the design, implementation, and supervision of therapeutic exercise programs for orthopedic injuries and disorders. The book's logical five-part organization begins with an instructive look at the foundations of the rehabilitation process, then covers the treatment of physiologic impairments during rehabilitation; rehabilitation tools; intervention strategies; and special considerations for specific patient populations. Features Helpful review of the foundations of the rehabilitation process, thorough coverage of managing the healing process through rehabilitation, and an algorithm-based approach to musculoskeletal rehabilitation Complete survey of rehabilitation tools, from isokinetics, aquatic therapy, and orthotics, to a four-step clinical model for the essentials of functional exercise Full chapters on functional progressions and functional testing and unique coverage of core stabilization training, impaired function, and impaired muscular control Unique coverage of a functional movement screen A practical system for history-taking and scanning Unique coverage of how to treat special segments of the population, including geriatric and pediatric patients, amputees, and the active female An easy-to-follow body region approach to intervention strategies Handy appendices covering the American College of Sports Medicine position statements on strength training and fitness development An abundance of study-enhancing illustrations, plus clinical pearls and protocols designed to speed clinical decision making
This lavishly illustrated book examines the distribution, ecology, conservation status, and biogeography of 176 species of dragonflies in the southern plains of the United States, where twelve ecoregions converge. The topics discussed, such as phenotypic variation and ecology, are applicable and of interest across the United States and much of north America, and will appeal to researchers and dragonfly enthusiasts alike. A series of maps, including a distributional map by specific locality of occurrence, indicate level of documentation and allow the reader to visualize the biogeographical associations of a given species. These maps also encourage citizen scientists to contribute documentation wherever they spend time in the field. Context-driven chapters, including one on the region’s rich paleontological history, blend environmental history and biogeography, giving the book a fresh perspective on the natural world while providing a rich summary of the odonates. Dragonflies at a Biographical Crossroads: The Odonata of Oklahoma and Complexities Beyond Its Borders will be sought out by dragonfly researchers and enthusiasts, entomologists, amateur naturalists, paleontologists, conservation biologists, educators, regional historians, and those seeking to meld the disciplines of cultural and environmental history with biology. It will also be readily accessible to the lay public. Dragonflies combine the visually stunning with acrobatic fireworks in ways no other insect can hope to combine.
Ideal for fellows and practicing pulmonologists who need an authoritative, comprehensive reference on all aspects of pulmonary medicine, Murray and Nadel’s Textbook of Respiratory Medicine offers the most definitive content on basic science, diagnosis, evaluation and treatment of the full spectrum of respiratory diseases. Full-color design enhances teaching points and highlights challenging concepts. Understand clinical applications and the scientific principles of respiratory medicine. Detailed explanations of each disease entity allow you to work through differential diagnoses. Expert Consult eBook version included with purchase. This enhanced eBook experience offers content updates, videos, review questions, and Thoracic Imaging Cases (TICs), all of which are easily navigable on any device for access on rounds or in the clinic. Includes more than 1,000 figures and over 200 videos and audio files. Key Points and Key Reading sections highlight the most useful references and resources for each chapter. An expanded sleep section now covers four chapters and includes control of breathing, consequences of sleep disruption, as well as obstructive and central apnea. New chapters in the Critical Care section cover Noninvasive Ventilation (NIV) and Extracorporeal Support of Gas Exchange (ECMO). New chapters focusing on diagnostic techniques now include Invasive Diagnostic Imaging and Image-Guided Interventions and Positron Emission Tomography, and a new chapter on Therapeutic Bronchoscopy highlights the interventional role of pulmonologists. Embedded videos feature thoracoscopy, therapeutic bronchoscopy, volumetric chest CT scans, and more. Brand-new audio files highlight normal and abnormal breath sounds and the separate components of cough.
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