The fields of molecular evolution, genome evolution, and evolutionary genetics are now well-established. Remarkably, however, although all evolutionary modifications begin at the cellular level, and despite the advances made in cell biology and microbiology over the past few decades, there is as yet no recognised discipline of evolutionary cell biology. The goal of this book is to help establish the foundations for this emerging field. Its principal aims are twofold: firstly, to promote an understanding among evolutionary biologists as to why the cellular details matter if we are to understand the mechanisms of evolution; secondly, to make clear to non-evolutionary biologists - cell biologists in particular - that evolution is not just a matter of natural selection and optimization, but a process whose reach depends on other population genetic features such as mutation, recombination, and random genetic drift. Although there are many excellent books on cell biology, microbiology, and biophysics, almost no attention is given to evolution. Likewise, although there are numerous evolutionary biology books on the market, none of them gives more than passing attention to details at the cellular level. Thus Evolutionary Cell Biology is genuinely novel, offering a broader understanding of evolutionary processes and an appreciation for the many interesting problems that remain to be solved at the cellular and subcellular levels. This advanced textbook is aimed at both cell biologists and evolutionary biologists. It will be accessible to upper-level undergraduates in biology, and certainly to graduate students in all areas of the life sciences. Professionals from a wide range of fields - cell biology, microbiology, evolution, biophysics, biochemistry, and mathematics - will be exposed to entirely new ideas not traditionally covered in their primary fields of expertise.
This book examines the current literature and knowledge on the evolution and ecology of all the birds named as eagles, with particular emphasis on the larger species. It also examines the past and current relations between eagles and people, including habitat change and conservation issues. Eagle ecologies and conservation are currently seriously impacted by human activities such as industrialization, urbanization, pollution, deforestation and hunting. Some eagle species have consequently experienced extreme population changes. There are, however, some positive developments. Eagles have a strong, historic bond with human civilization, due to their status as the world’s most charismatic birds. Conservation policies have also been successful in repopulating some ecosystems with breeding eagles. Therefore, despite the complexity of this relationship, there may yet be hope for this unique species group, frequently rated as the kings of birds, and symbolic of human power, ambition, royalty, nationality, and even concepts of God. It is hoped that this book will contribute to the further understanding of these unique and fantastic birds.
Shame, the quintessential human emotion, received little attention during the years in which the central forces believed to be motivating us were identified as primitive instincts like sex and aggression. Now, redressing the balance, there is an explosion of interest in the self-conscious emotion. Much of our psychic lives involve the negotiation of shame, asserts Michael Lewis, internationally known developmental and clinical psychologist. Shame is normal, not pathological, though opposite reactions to shame underlie many conflicts among individuals and groups, and some styles of handling shame are clearly maladaptive. Illustrating his argument with examples from everyday life, Lewis draws on his own pathbreaking studies and the theory and research of many others to construct the first comprehensive and empirically based account of emotional development focused on shame. In this paperback edition, Michael Lewis adds a compelling new chapter on stigma in which he details the process in which stigmatization produces shame.
The recent devastation caused by tsunamis, hurricanes and wildfires highlights the need for highly trained professionals who can develop effective strategies in response to these disasters. This invaluable resource arms readers with the tools to address all phases of emergency management. It covers everything from the social and environmental processes that generate hazards to vulnerability analysis, hazard mitigation, emergency response, and disaster recovery.
The premier single-volume reference in the field of anesthesia, Clinical Anesthesia is now in its Sixth Edition, with thoroughly updated coverage, a new full-color design, and a revamped art program featuring 880 full-color illustrations. More than 80 leading experts cover every aspect of contemporary perioperative medicine in one comprehensive, clinically focused, clear, concise, and accessible volume. Two new editors, Michael Cahalan, MD and M. Christine Stock, MD, join Drs. Barash, Cullen, and Stoelting for this edition. A companion Website will offer the fully searchable text, plus access to enhanced podcasts that can be viewed on your desktop or downloaded to most Apple and BlackBerry devices. This is the tablet version which does not include access to the supplemental content mentioned in the text.
Handbook of Supportive and Palliative Radiation Oncology serves as a practical tool and rapid reference to assist radiation oncology practitioners in direct patient care with common palliative care issues. Containing the most recent advances in translational palliative care research, each chapter is organized in a succinct fashion to discuss major symptom burdens, suggested assessment, and various management options. Each symptom and disease section is written to be a rapid, practical guide for clinicians on the floor. The book starts with general approaches in palliative radiation oncology that are followed by a section that focuses on common symptoms in palliative care and their management. The next section of the book is devoted to site and disease-specific evaluation, intervention, and management. This handbook provides general guidelines and management recommendations for common clinical vignettes encountered by palliative radiation oncology practitioners and supported by palliative radiation oncology research. Concise references are cited to support treatment recommendation. - Provides a quick reference for the busy clinician - Details standard of care resources for researchers of palliative and supportive care - Contains updated standards of care for palliative medicine and a list of common medications and dosages - Includes a comprehensive index by symptom and condition to facilitate quick reference
Organic Synthesis 5e provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature.? There have been advancements in organic reactions, particularly organometallic reactions, and there is a need to show how these advancements have influenced current organic synthesis. The goal is to revise and update the examples of reaction examples taken from the synthesis literature from about 2017-2023. The reactions illustrate those that are used most often in modern organic synthesis, but recent examples will show their current relevance.? Where new approaches and new reactions have been developed for organic synthesis, examples will be added as new material. - Provides new content, reaction examples, and study problems from recent research? - Features improved organization, new art, and new chapter content on process chemistry and green organic chemistry - Includes revised homework for each chapter, with new examples and questions?
First published in 1998, this volume contains essays from leading thinkers on both sides of the Atlantic on the relationship between law and science. Science plays an ever-increasing part in the development of legislation and the adjudication of cases. Its limitations and its value are explored in these essays which discuss issues of methodology and of evidence. Amongst areas covered are silicone breast implants, the rape trauma syndrome, the environment, inventions and Bayesianism.
Those in the counseling profession are interacting more with people from other cultures, the U.S. sphere of influence throughout the world is spreading, increasingly, we are providing services to clients who are not Caucasian or of European heritage, and our educational programs have been active in training both domestic students of diverse ethnic backgrounds as well as foreign students. These factors combine to contribute to the need for those who provide counseling to understand the elements involved in interacting with a wide spectrum of people. This book meets that need by providing a brief synopsis on such topics as common factors, values, universals, cross-cultural competence, and models, approaches, and psychological perspectives of human behavior (theories of personality). The emphasis is on material that relies more on the use of the scientific method and data instead of anecdotal and experiential literature. For the reader who is interested in obtaining information from which statements are derived, there are references to investigate the material further. Unlike other book that stress the barriers between counselor and client, this book adds the perspective that there are factors that facilitate interactions between the two. There are also frequent cross-cultural examples in the book. To facilitate awareness of similarities and differences in views of human behavior, samples of African, Arab, Chinese, and European/American perspectives are represented. There is also a relatively large section on applications. This consists of such subjects as cross-cultural aspects of psychological theories, ethics, research, tests, Euro-American approaches and experiences, client characteristics, client and counselor interactions, and therapeutic techniques. Many other topics are covered, as well. Students and professionals in the fields of counseling and psychology will find this book to be an invaluable addition to their library.
Since its first edition over 60 years ago, Rockwood and Green’s Fractures in Adults has been the go-to reference for treating a wide range of fractures in adult patients. The landmark, two-volume tenth edition continues this tradition with two new international editors, a refreshed mix of contributors, and revised content throughout, bringing you fully up to date with today’s techniques and technologies for treating fractures in orthopaedics. Drs. Paul Tornetta III, William M. Ricci, Robert F. Ostrum, Michael D. McKee, Benjamin J. Ollivere, and Victor A. de Ridder lead a team of experts who ensure that the most up-to-date information is presented in a comprehensive yet easy to digest manner.
The second edition of this well-received text advocates for a transformational change in the way doctors protect their mental health, look out for their colleagues, co-create a kinder, more humane work culture and lead health system reform. Offering practical strategies and real solutions, based both on medical literature and the wisdom of experienced doctors, the new edition reimagines healthcare, where every doctor is encouraged and supported to: Prioritise psychological wellbeing and physical protection Promote healthy workplace cultures, fairness and safety Build strong relationships by sharing challenges Save lives through medical co-leadership Rediscover the joy in medicine Brimming with poignant and hopeful stories and quotes from a diverse array of doctors from many different specialities and at all career stages, the book is a celebration of the growing global interconnectedness and the changing face of the medical profession. An invaluable support and companion for those in the early years of medicine, Every Doctor is a must-read for all doctors across all specialties and wherever they practise in the world, because exemplary care of patients, peers, profession and self is a lifelong journey.
This book takes a systematic and holistic approach to examining all 41 peacemaking initiatives used to settle the Cyprus question from 1955 onward under the auspices of the United Nations and/or other actors in the international system, including the United States, Canada, the UK, Greece and Turkey. The analysis of peacemaking strategies, dynamics and obstacles fleshes out numerous relationships between: (i) peacemaking processes, dynamics and outcomes, from signaling to negotiations and to post-accord completion and implementation; (ii) concessions, constraints and leverage during peacemaking negotiations and third party mediation; and (iii) obstacles to finding an endgame solution and satisfying conditions for lasting peace expectations that all parties can agree on and implement successfully. After documenting 62 interviews with top political leaders in Cyprus (including top tier elected elites and third party mediators) and about 70 more interviews with key informants (including academics, researchers, members of negotiating teams, technical committees and working groups), this book concludes with a plethora of descriptive, as well as prescriptive, propositions on how peacemaking processes could lead to more sustainable and implementable peacemaking initiatives in Cyprus and in similar protracted and seemingly intractable cases.
Thoroughly revised and reorganized, this 2nd edition offers you meticulous how-to-do-it guidance on performing today’s top radiographically guided regional anesthesia and pain management techniques. Renowned experts explain how to make optimal use of fluoroscopy, MRI, and CT to pinpoint the exact anatomic site for each procedure. Provides fluoroscopic, MR, and CT images coupled with distinct line drawings for each procedure to ensure proper positioning and easy application of techniques. Offers easy-to-follow step-by-step descriptions addressing every aspect of patient positioning, the use of radiographic solutions for tissue-specific enhancement, and correct techniques for anesthesia/analgesia administration so you can be sure your patient will be pain free throughout the procedure. Discusses possible complications to help you avoid mistakes. Includes descriptions of procedures for each image guided technique as well as the approaches available for such imaging so you can choose the correct procedure for every patient. Features two new sections Advanced Techniques and Emerging Techniques, incorporates new procedures into the upper and lower extremity and head and neck chapters, and revises all other chapters substantially to put you on the cusp of the latest advances in the field. Uses nearly 1,600 crisp illustrations, 50% new to this edition, to illuminate every concept. Presents a complete reorganization by body region and focused content to help you get to the information you need quickly.
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