Absolutely Small presents (and demystifies) the world of quantum science like no book before. Physics is a complex, daunting topic, but it is also deeply satisfying?even thrilling. When liberated from its mathematical underpinnings, physics suddenly becomes accessible to anyone with the curiosity and imagination to explore its beauty. Science without math? It’s not that unusual. For example, we can understand the concept of gravity without solving a single equation. So for all those who may have pondered what makes blueberries blue and strawberries red; for those who have wondered if sound really travels in waves; and why light behaves so differently from any other phenomenon in the universe, it’s all a matter of quantum physics. This book explores in considerable depth scientific concepts using examples from everyday life, such as: particles of light, probability, states of matter, what makes greenhouse gases bad Challenging without being intimidating, accessible but not condescending, Absolutely Small develops your intuition for the very nature of things at their most basic and intriguing levels.
Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book: Provides a comprehensive account of inference techniques in systems biology. Introduces classical and Bayesian statistical methods for complex systems. Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems. Discusses various applications for statistical systems biology, such as gene regulation and signal transduction. Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies. Presents an in-depth presentation of reverse engineering approaches. Provides colour illustrations to explain key concepts. This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.
The 35 essays collected here report on many new diagnostic and therapeutic aspects of endoscopy. The topics covered include endoscopic ultrasonography, videoendoscopy, percutaneous endoscopic gastronomy tube placement, hydrostatic dilators and overtubes. A special section is devoted to biliary stent, balloon dilation of biliary strictures, and nasobiliary drains. In addition, the various methods for achieving hemostasis in gastrointestinal bleeding are reviewed and an endoscopic videoquiz is provided.
An Introduction to Political Geography provides a broad-based introduction to how power interacts with space; how place influences political identities; and how policy creates and remoulds territory. By pushing back the boundaries of what we conventionally understand as political geography, the book emphasizes the interactions between power, politics and policy, space, place and territory in different geographical contexts. This is both an essential text for political geographers and also a valuable resource for students of related fields with an interest in politics and geography.
Indices, index funds and ETFs are grossly inaccurate and inefficient and affect more than €120 trillion worth of securities, debts and commodities worldwide. This book analyzes the mathematical/statistical biases, misrepresentations, recursiveness, nonlinear risk and homomorphisms inherent in equity, debt, risk-adjusted, options-based, CDS and commodity indices – and by extension, associated index funds and ETFs. The book characterizes the “Popular-Index Ecosystems,” a phenomenon that provides artificial price-support for financial instruments, and can cause systemic risk, financial instability, earnings management and inflation. The book explains why indices and strategic alliances invalidate Third-Generation Prospect Theory (PT3), related approaches and most theories of Intertemporal Asset Pricing. This book introduces three new decision models, and some new types of indices that are more efficient than existing stock/bond indices. The book explains why the Mean-Variance framework, the Put-Call Parity theorem, ICAPM/CAPM, the Sharpe Ratio, Treynor Ratio, Jensen’s Alpha, the Information Ratio, and DEA-Based Performance Measures are wrong. Leveraged/inverse ETFs and synthetic ETFs are misleading and inaccurate and non-legislative methods that reduce index arbitrage and ETF arbitrage are introduced.
Computer Security in the Workplace - A Quick and Simple Guide lives up to its name by providing fast and easy tips and suggestions to help make computer users of any level the strongest link in their company's security. With this book you can learn more about computer security in an hour, than most people do in a lifetime.
with some 600 photos and 4000 drawings and plans, the Timber Construction Manual is a comprehensive and indispensable reference work in the specialist literature on timber. It looks at all types of timber and timber materials, also presenting detailed information on the current norms and standards. Chapters cover the basic principles of working with timber, providing detailed information on subjects such as heat, noise insulation, fire protection treatment. The significance of timber with particular reference to ecology is also investigated. Timber as a load-bearing material is considered, and topics such as new methods of joining, transport and montage are documented. The second part of the volume presents a large number of built examples which feature some "classic" structures but focus chiefly on more recent buildings. The spectrum presented ranges from heavy-load bridges to multi-storey residential buildings. The second part of the examples looks specifically at topics such as facades, building skins etc.
This practical volume provides a thorough introduction to conducting and critically reading research in technical communication, complete with exemplars of research articles for study. Offering a solid grounding in the research underpinnings of the technical communication field, this resource has been developed for use in master’s level and upper-division undergraduate research methods courses in technical and professional communication.
With Web access becoming available through TV, handheld devices, and even phones, developers need to create sites that can be viewed from different environments, not just from the desktop. Introducing XHTML, the next generation HTML, this practical guide jumpstarts Web developers on the technology that ensures that their Web pages stay true-to-form on any available platform. Using extensive code and real-world examples, XML expert Michael Sauers teaches readers how to apply XHTML quickly and effectively without having to become XML programmers first. Readers will learn how to migrate legacy HTML documents to XHTML and create documents and applications for a variety of platforms. Like the other books in the series, an appendix listing will feature where to find updated information, a source code index, and other handy features.
Statistical Parameters is a unique new guide to current statistical methods and research. Based on a series of interdisciplinary lectures for users of statistical methods in research and development, this book provides insights into data acquisition and statistical interpretation. The author discusses practical problems in a consistent methodologic
This timely book presents strategies for mitigation of the greenhouse effect. It provides practical counter measures to reduce the emission of greenhouse gases. Key substitute technologies discussed include energy efficiency and conservation, biomass, and nuclear energy. These technologies are both mature and can be applied on a large scale. Important concepts can apply to other technologies as well. Technologies for a Greenhouse-Constrained Society will help scientists and engineers identify the technological and policy actions needed to counteract the greenhouse effect. Solutions are aimed at both developed and developing countries. Technologies for a Greenhouse-Constrained Society will appeal to environmental engineers and scientists, meteorologists, social scientists, geologists, educators, fuel engineers, energy engineers, economists, and others interested in this field.
Tentative estimates suggest that one in ten patients suffers from an adverse event in hospital. In Germany, approx. 1.8 million out of approx. 18 million inpatients suffer from adverse events; 50 percent of these cases are estimated to be avoidable. In the US, nearly 100,000 people die from the consequences of mistreatment. The intensive care units record 1.7 medical errors per patient and day. The most affected disciplines are the operative disciplines, particularly general surgery. Medical errors mainly occur when the indication for surgery is being made, during surgery and post-surgery. Suspicious oncological diagnostic results and post-operative complications are also often ignored. This book deals with complications and typical medical errors in surgery. It shows solutions and ways of dealing effectively with these errors and how to establish an efficient security management system.
Wireless Distributed Computing and Cognitive Sensing defines high-dimensional data processing in the context of wireless distributed computing and cognitive sensing. This book presents the challenges that are unique to this area such as synchronization caused by the high mobility of the nodes. The author will discuss the integration of software defined radio implementation and testbed development. The book will also bridge new research results and contextual reviews. Also the author provides an examination of large cognitive radio network; hardware testbed; distributed sensing; and distributed computing.
A vital, timely text on the viruses that cause pandemics and how to face them, by the New York Times bestselling author of How Not to Die. From tuberculosis to bird flu and HIV to coronavirus, these infectious diseases share a common origin story: human interaction with animals. Otherwise known as zoonotic diseases for their passage from animals to humans, these pathogens—both pre-existing ones and those newly identified—emerge and re-emerge throughout history, sparking epidemics and pandemics that have resulted in millions of deaths around the world. How did these diseases come about? And what—if anything—can we do to stop them and their fatal march into our countries, our homes, and our bodies? In How to Survive a Pandemic, Dr. Michael Greger, physician and internationally-recognized expert on public health issues, delves into the origins of some of the deadliest pathogens the world has ever seen. Tracing their evolution from the past until today, Dr. Greger spotlights emerging flu and coronaviruses as he examines where these pathogens originated, as well as the underlying conditions and significant human role that have exacerbated their lethal influence to large, and even global, levels. As the world grapples with the devastating impact of the novel coronavirus 2019, Dr. Greger reveals not only what we can do to protect ourselves and our loved ones during a pandemic, but also what human society must rectify to reduce the likelihood of even worse catastrophes in the future.
A vital, timely text on the viruses that cause pandemics and how to face them, by the New York Times bestselling author of How Not to Die. As the world grapples with the devastating impact of COVID-19, Dr Michael Greger reveals not only what we can do to protect ourselves and our loved ones during a pandemic, but also what human society must rectify to reduce the likelihood of even worse catastrophes in the future. From tuberculosis to bird flu and HIV to coronavirus, these infectious diseases share a common origin story: human interaction with animals. Otherwise known as zoonotic diseases for their passage from animals to humans, these pathogens – both pre-existing ones and those newly identified – emerge and re-emerge throughout history, sparking epidemics and pandemics that have resulted in millions of deaths around the world. How did these diseases come about? And what – if anything – can we do to stop them and their fatal march into our countries, our homes, and our bodies? In How to Survive a Pandemic, Dr Michael Greger, physician and internationally-recognized expert on public health issues, delves into the origins of some of the deadliest pathogens the world has ever seen. Tracing their evolution from the past until today, Dr Greger spotlights emerging flu and coronaviruses as he examines where these pathogens originated, as well as the underlying conditions and significant human role that have exacerbated their lethal influence to large, and even global, levels.
This text provides an introduction to the theory of partial differential equations. It introduces basic examples of partial differential equations, arising in continuum mechanics, electromagnetism, complex analysis and other areas, and develops a number of tools for their solution, including particularly Fourier analysis, distribution theory, and Sobolev spaces. These tools are applied to the treatment of basic problems in linear PDE, including the Laplace equation, heat equation, and wave equation, as well as more general elliptic, parabolic, and hyperbolic equations. Companion texts, which take the theory of partial differential equations further, are AMS volume 116, treating more advanced topics in linear PDE, and AMS volume 117, treating problems in nonlinear PDE. This book is addressed to graduate students in mathematics and to professional mathematicians, with an interest in partial differential equations, mathematical physics, differential geometry, harmonic analysis, and complex analysis.
Eine umfassende Einführung zur Rolle der Epidemiologie in der Veterinärmedizin. Die vollständig überarbeitete und erweiterte Ausgabe von Veterinary Epidemiology führt den Leser in das Fachgebiet der Veterinärepidemiologie ein. Diese neue Auflage bietet auch neue Kapitel zur Konzeption von Beobachtungsstudien, Validität von epidemiologischen Studien, zu systematischen Prüfungen und zu statistischen Modellen. Die aktualisierte Auflage beginnt mit einem historischen Blick auf die Entwicklung der Veterinärmedizin. Im Anschluss wird die Fachrichtung Epidemiologie umfassend beleuchtet. Kapitel befassen sich mit den Aspekten Kausalität, Auftreten von Krankheiten, Bestimmungsfaktoren, Krankheitsmustern, Krankheitsökologie u.v.m. Veterinary Epidemiology, 4. Auflage: - Alle Kapitel wurden aktualisiert. Entstanden ist ein modernes Referenzwerk zum Thema Veterinärepidemiologie. - Enthält neue Kapitel, die für die Entwicklung des Fachgebiets maßgeblich sind. - Bietet Beispiele zu Haustieren, Nutztieren und Vögeln sowie zu Krankheiten bei Wassertieren. - Richtet den Fokus auf Prinzipien und Konzepte der Epidemiologie, der Überwachung, der Validierung und Leistungsfähigkeit diagnostischer Tests. - Begleitende Website mit Multiple-Choice-Fragen.
This book is intended to be a comprehensive introduction to the subject of partial differential equations. It should be useful to graduate students at all levels beyond that of a basic course in measure theory. It should also be of interest to professional mathematicians in analysis, mathematical physics, and differential geometry. This work will be divided into three volumes, the first of which focuses on the theory of ordinary differential equations and a survey of basic linear PDEs.
The volume comprises five extended surveys on the recent theory of viscosity solutions of fully nonlinear partial differential equations, and some of its most relevant applications to optimal control theory for deterministic and stochastic systems, front propagation, geometric motions and mathematical finance. The volume forms a state-of-the-art reference on the subject of viscosity solutions, and the authors are among the most prominent specialists. Potential readers are researchers in nonlinear PDE's, systems theory, stochastic processes.
A volume in the popular FactsBook Series, the First Edition of The Leucocyte Antigen FactsBook was hugely successful. The new Second Edition has been completely revised, updated, and expanded by 65% to include new findings and up-to-date key references. The introductory chapters have also been updated, especially in terms of nomenclature, the role of the World Wide Web, and new structural data. The Leucocyte Antigen FactsBook, Second Edition contains more than 200 entries, with approximately 70 new entries, on all the molecules specifically expressed in the surface of cells of the haematopoietic system, including all characterized CD antigens, antigen receptors, MHC antigens, adhesion molecules, and cytokine receptors. This FactsBook will be of enormous value to immunologists, cell biologists, biochemists, and endocrinologists.Key Features* Completely up-to-date* Revised and expanded to include over 70 new entries* More than 200 entries in total, plus additional introductory material* New structural data* New nomenclature for CD and related molecules covered
The first of three volumes on partial differential equations, this one introduces basic examples arising in continuum mechanics, electromagnetism, complex analysis and other areas, and develops a number of tools for their solution, in particular Fourier analysis, distribution theory, and Sobolev spaces. These tools are then applied to the treatment of basic problems in linear PDE, including the Laplace equation, heat equation, and wave equation, as well as more general elliptic, parabolic, and hyperbolic equations. The book is targeted at graduate students in mathematics and at professional mathematicians with an interest in partial differential equations, mathematical physics, differential geometry, harmonic analysis, and complex analysis. The third edition further expands the material by incorporating new theorems and applications throughout the book, and by deepening connections and relating concepts across chapters. In includes new sections on rigid body motion, on probabilistic results related to random walks, on aspects of operator theory related to quantum mechanics, on overdetermined systems, and on the Euler equation for incompressible fluids. The appendices have also been updated with additional results, ranging from weak convergence of measures to the curvature of Kahler manifolds. Michael E. Taylor is a Professor of Mathematics at the University of North Carolina, Chapel Hill, NC. Review of first edition: “These volumes will be read by several generations of readers eager to learn the modern theory of partial differential equations of mathematical physics and the analysis in which this theory is rooted.” (Peter Lax, SIAM review, June 1998)
An updated and thoroughly revised third edition of the foundational text offering an introduction to physics with a comprehensive interactive website The revised and updated third edition of Understanding Physics presents a comprehensive introduction to college-level physics. Written with today's students in mind, this compact text covers the core material required within an introductory course in a clear and engaging way. The authors – noted experts on the topic – offer an understanding of the physical universe and present the mathematical tools used in physics. The book covers all the material required in an introductory physics course. Each topic is introduced from first principles so that the text is suitable for students without a prior background in physics. At the same time the book is designed to enable students to proceed easily to subsequent courses in physics and may be used to support such courses. Relativity and quantum mechanics are introduced at an earlier stage than is usually found in introductory textbooks and are integrated with the more 'classical' material from which they have evolved. Worked examples and links to problems, designed to be both illustrative and challenging, are included throughout. The links to over 600 problems and their solutions, as well as links to more advanced sections, interactive problems, simulations and videos may be made by typing in the URL’s which are noted throughout the text or by scanning the micro QR codes given alongside the URL’s, see: http://up.ucc.ie This new edition of this essential text: Offers an introduction to the principles for each topic presented Presents a comprehensive yet concise introduction to physics covering a wide range of material Features a revised treatment of electromagnetism, specifically the more detailed treatment of electric and magnetic materials Puts emphasis on the relationship between microscopic and macroscopic perspectives Is structured as a foundation course for undergraduate students in physics, materials science and engineering Has been rewritten to conform with the revised definitions of SI base units which came into force in May 2019 Written for first year physics students, the revised and updated third edition of Understanding Physics offers a foundation text and interactive website for undergraduate students in physics, materials science and engineering.
Colorectal Surgery equips you to overcome the clinical challenges you face in this area of surgery. Written for the general surgeon who is called upon to manage diseases and disorders of the large bowel, rectum, and anus, this reference provides advanced, expert guidance on how to avoid complications and achieve the most successful results. Visualize relevant anatomy and techniques more easily with high-quality, full-color line drawings and clinical photos throughout. Zero in on the information you need with key points boxes in every chapter that provide a quick overview of the topic at hand. Get practical, hands-on advice on managing the diseases and disorders you’re most likely to encounter. Learn from acknowledged leaders in the field who excel in both academic and clinical areas.
Kosorok’s brilliant text provides a self-contained introduction to empirical processes and semiparametric inference. These powerful research techniques are surprisingly useful for developing methods of statistical inference for complex models and in understanding the properties of such methods. This is an authoritative text that covers all the bases, and also a friendly and gradual introduction to the area. The book can be used as research reference and textbook.
The first systematic assessment of the symphonic style of the Czech composer Bohuslav Martinu [1890-1959], tracing the evolution of his musical language and including detailed analyses of all six symphonies. Over the past few decades the music of the Czech composer Bohuslav Martinu (1890-1959) has enjoyed a slow but steady rise in popularity, and his six symphonies, written between 1942 and 1953, have now been recorded many times; concert performances are on the increase, too. But Martinu and the Symphony is not only the first book in English intended to help the music-lover to a deeper understanding of these glorious works - it is by far the most comprehensive work on the subject in any language. Each Symphony is examined in turn, the analyses revealing what makes each creation so individual yet also so clearly part of a close-knit family of works and identifying the elements of his melodic, harmonic and instrumental style which produce Martinu's very personal vibrant and organic symphonic manner. Martinu and the Symphony is illustrated with almost 200 musical examples, taken not only fromthe Symphonies but also from his other works for large orchestra. His path to symphonic mastery is examined in unprecedented detail: attention is at last paid to the early orchestral works which, although largely unperformed andunpublished even now, afford fascinating glimpses of the composer to come. A study of the late triptychs The Frescoes of Piero della Francesca and The Parables rounds out this appraisal of Martinus enthralling symphonic and orchestral legacy.
The algorithmic solution of problems has always been one of the major concerns of mathematics. For a long time such solutions were based on an intuitive notion of algorithm. It is only in this century that metamathematical problems have led to the intensive search for a precise and sufficiently general formalization of the notions of computability and algorithm. In the 1930s, a number of quite different concepts for this purpose were pro posed, such as Turing machines, WHILE-programs, recursive functions, Markov algorithms, and Thue systems. All these concepts turned out to be equivalent, a fact summarized in Church's thesis, which says that the resulting definitions form an adequate formalization of the intuitive notion of computability. This had and continues to have an enormous effect. First of all, with these notions it has been possible to prove that various problems are algorithmically unsolvable. Among of group these undecidable problems are the halting problem, the word problem theory, the Post correspondence problem, and Hilbert's tenth problem. Secondly, concepts like Turing machines and WHILE-programs had a strong influence on the development of the first computers and programming languages. In the era of digital computers, the question of finding efficient solutions to algorithmically solvable problems has become increasingly important. In addition, the fact that some problems can be solved very efficiently, while others seem to defy all attempts to find an efficient solution, has called for a deeper under standing of the intrinsic computational difficulty of problems.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
The core of this monograph is the development of tools to derive well-posedness results in very general geometric settings for elliptic differential operators. A new generation of Calderón-Zygmund theory is developed for variable coefficient singular integral operators, which turns out to be particularly versatile in dealing with boundary value problems for the Hodge-Laplacian on uniformly rectifiable subdomains of Riemannian manifolds via boundary layer methods. In addition to absolute and relative boundary conditions for differential forms, this monograph treats the Hodge-Laplacian equipped with classical Dirichlet, Neumann, Transmission, Poincaré, and Robin boundary conditions in regular Semmes-Kenig-Toro domains. Lying at the intersection of partial differential equations, harmonic analysis, and differential geometry, this text is suitable for a wide range of PhD students, researchers, and professionals. Contents: Preface Introduction and Statement of Main Results Geometric Concepts and Tools Harmonic Layer Potentials Associated with the Hodge-de Rham Formalism on UR Domains Harmonic Layer Potentials Associated with the Levi-Civita Connection on UR Domains Dirichlet and Neumann Boundary Value Problems for the Hodge-Laplacian on Regular SKT Domains Fatou Theorems and Integral Representations for the Hodge-Laplacian on Regular SKT Domains Solvability of Boundary Problems for the Hodge-Laplacian in the Hodge-de Rham Formalism Additional Results and Applications Further Tools from Differential Geometry, Harmonic Analysis, Geometric Measure Theory, Functional Analysis, Partial Differential Equations, and Clifford Analysis Bibliography Index
Networks provide a very useful way to describe a wide range of different data types in biology, physics and elsewhere. Apart from providing a convenient tool to visualize highly dependent data, networks allow stringent mathematical and statistical analysis. In recent years, much progress has been achieved to interpret various types of biological network data such as transcriptomic, metabolomic and protein interaction data as well as epidemiological data. Of particular interest is to understand the organization, complexity and dynamics of biological networks and how these are influenced by network evolution and functionality. This book reviews and explores statistical, mathematical and evolutionary theory and tools in the understanding of biological networks. The book is divided into comprehensive and self-contained chapters, each of which focuses on an important biological network type, explains concepts and theory and illustrates how these can be used to obtain insight into biologically relevant processes and questions. There are chapters covering metabolic, transcriptomic, protein interaction and epidemiological networks as well as chapters that deal with theoretical and conceptual material. The authors, who contribute to the book, are active, highly regarded and well-known in the network community.
The author emphasizes a non-uniform ellipticity condition as the main approach to regularity theory for solutions of convex variational problems with different types of non-standard growth conditions. This volume first focuses on elliptic variational problems with linear growth conditions. Here the notion of a "solution" is not obvious and the point of view has to be changed several times in order to get some deeper insight. Then the smoothness properties of solutions to convex anisotropic variational problems with superlinear growth are studied. In spite of the fundamental differences, a non-uniform ellipticity condition serves as the main tool towards a unified view of the regularity theory for both kinds of problems.
The Handbook of Environmental Health-Pollutant Interactions in Air, Water, and Soil includes Nine Chapters on a variety of topics basically following a standard chapter outline where applicable with the exception of Chapters 8 and 9. The outline is as follows:1. Background and status2. Scientific, technological and general information3. Statement o
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