This book proposes another unique basis for the origins of religion from disturbances in brain function. It proposes the novel idea that near-death and out-of-body experiences (ND/OBE) engendered “a sense of the divine” in ancient man. As the author points out, key aspects of ND/OBE are thematic of all later established religions. These include journeys to heaven, sightings of brightly-lit godlike figures, and dead people now alive. Thus, ND/OBE could be the originating source of these spiritual motifs. To this, the author adds a fourth factor: various brain influences contribute to or modulate ND/OBE. Such cognate neurological disorders include REM-sleep intrusions, sleep paralysis, narcolepsy, and the Guillain-Barré syndrome. Errors due to aberrant switching between key neural control centers disrupt critical state-boundaries between consciousness and dreaming. This may induce NDE. Thus, in this state, subjects temporarily fail to understand where they are, undergo loss of self, and detached from the world. They imagine a “union with Gods.” Here, then, is the biological basis of ineffability. Ancient humans gained beliefs about the "supernatural" through day-to-day existence. This book argues that near death experiences and cognate neurological conditions, some genetically-determined, could have facilitated, even augmented such beliefs. Hence, in configuring another realm of “spiritual” experience beyond the known environment, these neurological possibilities offer effective traction.
Discrediting 'mystical' or 'psychical' interpretations of out-of-body and near-death experiences, Michael Marsh demonstrates how these phenomena are explicable in terms of brain neurophysiology and its neuropathological disturbances, and discusses the theological and philosophical implications of his hypotheses.
With the critical role of statistics in the design, conduct, analysis and reporting of clinical trials or observational studies intended for regulatory purposes, numerous guidelines have been issued by regulatory authorities around the world focusing on statistical issues related to drug development. However, the available literature on this important topic is sporadic, and often not readily accessible to drug developers or regulatory personnel. This book provides a systematic exposition of the interplay between the two disciplines, including emerging themes pertaining to the acceleration of the development of pharmaceutical medicines to serve patients with unmet needs. Features: Regulatory and statistical interactions throughout the drug development continuum The critical role of the statistician in relation to the changing regulatory and healthcare landscapes Statistical issues that commonly arise in the course of drug development and regulatory interactions Trending topics in drug development, with emphasis on current regulatory thinking and the associated challenges and opportunities The book is designed to be accessible to readers with an intermediate knowledge of statistics, and can be a useful resource to statisticians, medical researchers, and regulatory personnel in drug development, as well as graduate students in the health sciences. The authors’ decades of experience in the pharmaceutical industry and academia, and extensive regulatory experience, comes through in the many examples throughout the book.
For the first two thirds of the twentieth century, British government was among the most stable in the advanced industrial world. In the last three decades, the governing arrangements have been in turmoil and the country has been a pioneer in economic reform, and in public sector change. Inhis major new book, Michael Moran examines and explains the contrast between these two epochs. What turned Britain into a laboratory of political innovation? Britain became a formal democracy at the start of the twentieth century but the practice of government remained oligarchic. From the 1970sthis oligarchy collapsed under the pressure of economic crisis. The British regulatory state is being constructed in its place. Moran challenges the prevailing view that this new state is liberal or decentralizing. Instead he argues that it is a new, threatening kind of interventionist statewhich is colonizing, dominating, and centralizing hitherto independent domains of civil society. The book is essential reading for all those interested in British political development and in the nature and impact of regulation
The 34th Saas-Fee advanced course of the Swiss Society of Astronomy and Astrophysics (SSAA) took place from March 15 to 20, 2004, in Davos, on the subject of The Sun, Solar Analogs and the Climate. PresentlytheSwissmountainresortofDavosisprobablymostwellknown for hosting an event on globalization. However, it is because Davos also happens to be the seat of the Physikalisch-Meteorologisches Observatorium Davos and World Radiation Center, that this course on a “global” subject was hosted here. Exceptionally, the topic of this course was not purely astrophysical, but themembersoftheSSAAdecidedtosupportitallthesameduetothetimely topic of global warming and its possible link to solar variations. In these times of concern about global warming, it is important to und- stand solar variability and its interaction with the atmosphere. Only in this way can we distinguish between the solar and anthropogenic contributions to the rising temperatures. Therefore, this course addressed the observed va- ability of the Sun and the present understanding of the variability’s origin and its impact on the Earth’s climate. Comparing the solar variability with that of solar analog stars leads to a better understanding of the solar activity cycle and magnetic activity in general, and helps us to estimate how large the solar variations could be on longer time scales. Inspiteofthefantasticweatherandsnowconditionswhichreignedduring this week, the participants assiduously took part in the lectures. This is proof ofthehighqualityofthelecturesthatthethreespeakers,JoannaHaigh,Mike Lockwood and David Soderblom, delivered. We deeply thank them for their contributions and e?orts and hope that the readers will enjoy the book as much as we enjoyed their lectures.
Because Greek has a radically different alphabet to the Roman one used throughout the English-speaking world, Michael Kambas has used a simple transliteration system for both English to Greek and Greek to English in the dictionary section. Grammar and pronunciation explanations are linked into this useful system.
The first full-length study since the 1920s of the Restoration and eighteenth-century's revisions and revaluations of Shakespeare, and the first to consider the period's much-reviled stage adaptions in the context of the profound cultural changes of their times. Drawing on a wide range of evidence, Dobson examines how and why Shakespeare was retrospectively claimed as both a respectable Enlightenment author and a crucial and contested symbol of British national identity. The book provides thorough analysis, both engaging and informative, the definitive account of the theatre's role in establishing Shakespeare as Britain's National Poet. - ;The century between the Restoration and David Garrick's Stratford Jubilee saw William Shakespeare's promotion from the status of archaic, rustic playwright to that of England's timeless Bard, and with it the complete transformation of the ways in which his plays were staged, published, and read. But why Shakespeare, and what different interests did this process serve? The Making of the National Poet is the first full-length study since the 1920s of the Restoration and eighteenth century's revisions and revaluations of Shakespeare, and the first to consider the period's much-reviled stage adaptations in the context of the profound cultural changes in which they participate. Drawing on a wide range of evidence - including engravings, prompt-books, diaries, statuary, and previously unpublished poems (among them traces of the hitherto mysterious Shakespeare Ladies' Club) - it examines how and why Shakespeare was retrospectively claimed as both a respectable Enlightenment author and a crucial and contested symbol of British national identity. It shows in particular how the deification of Shakespeare co-existed with, and even demanded, the drastic and sometimes bizarre rewriting of his plays for which the period is notorious. The book provides thorough analysis, both engaging and informative, the definitive account of the theatre's role in establishing Shakespeare as Britain's National Poet. -
This dictionary was derived from the raw list of word roots and affixes collected by Dr. Duane King in his 1975 University of Georgia dissertation on the Cherokee language entitled A Grammar and Dictionary of the Cherokee Language of the Qualla Boundary in North Carolina. It includes many words that are not in the Cherokee-English Dictionary or other sources. It is our hope that this dictionary will not only expand and contribute to the preservation and growth of the Eastern dialects of the Cherokee language, but also be a resource that fills in gaps in other resources as it includes many words that are not in the Cherokee-English Dictionary or other sources.
Robert Boyle (1627-1691) was one of the most influential scientific and theological thinkers of his time. This is the first edition of his correspondence, transcribed from the original manuscripts. It is fully annotated, with an introduction and general index. Volume 6 covers the period of 1684–91.
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