“Details profound examples of life’s resilience and makes a convincing case that the natural world still has a lot worth fighting for.” —Paul Greenberg, New York Times bestselling author of Four Fish and The Climate Diet As climate change continues to intensify, the outlook for life on Earth often seems bleak. Yet hope for the future can be found in the “rescue effect,” which is nature’s innate ability to help organisms persist during hard times. Like a thermostat starting the air conditioning when a room gets too warm, the rescue effect automatically kicks in when organisms are stressed or declining. In The Rescue Effect, Michael Mehta Webster reveals the science behind nature’s inherent resilience, through compelling stories of species that are adapting to the changing world—including tigers in the jungles of India, cichlid fish in the great lakes of Africa, and corals in the Caribbean. In some cases, like the mountain pygmy-possum in the snowy mountains of southeast Australia, we risk losing species without intensive help from people. As observers to—and the cause of—species declines, we must choose whether and how to help, while navigating challenging questions about emerging technologies and the ethics of conservation actions. Ultimately, Webster argues that there are good reasons to expect a bright future, because everywhere we look, we can see evidence that nature can rescue many species from extinction; and when nature alone is not up to the task, we can help. Combining rigorous research with gripping storytelling, The Rescue Effect provides the cautious optimism we need to help save life on Earth.
“Details profound examples of life’s resilience and makes a convincing case that the natural world still has a lot worth fighting for.” —Paul Greenberg, New York Times bestselling author of Four Fish and The Climate Diet As climate change continues to intensify, the outlook for life on Earth often seems bleak. Yet hope for the future can be found in the “rescue effect,” which is nature’s innate ability to help organisms persist during hard times. Like a thermostat starting the air conditioning when a room gets too warm, the rescue effect automatically kicks in when organisms are stressed or declining. In The Rescue Effect, Michael Mehta Webster reveals the science behind nature’s inherent resilience, through compelling stories of species that are adapting to the changing world—including tigers in the jungles of India, cichlid fish in the great lakes of Africa, and corals in the Caribbean. In some cases, like the mountain pygmy-possum in the snowy mountains of southeast Australia, we risk losing species without intensive help from people. As observers to—and the cause of—species declines, we must choose whether and how to help, while navigating challenging questions about emerging technologies and the ethics of conservation actions. Ultimately, Webster argues that there are good reasons to expect a bright future, because everywhere we look, we can see evidence that nature can rescue many species from extinction; and when nature alone is not up to the task, we can help. Combining rigorous research with gripping storytelling, The Rescue Effect provides the cautious optimism we need to help save life on Earth.
The new, 5th Edition of Endocrine Secrets, by Michael McDermott, MD, continues the tradition of the highly popular Secrets Series®. A two-color page layout, question-and-answer approach, and chapter containing the “Top 100 Secrets offer a quick and current overview of essential knowledge in endocrinology. Updates throughout equip you with cutting-edge coverage, while new contributors present the latest perspectives. A wealth of user-friendly features-including valuable pearls, tips, and memory aids-help you to learn more efficiently. It all adds up to the perfect concise board review or handy clinical resource. Provides pearls, tips, and memory aids that help you learn more efficiently. Expedites reference and review with a question-and-answer format, bulleted lists, mnemonics, and tips from the authors. Includes a chapter containing the “Top 100 Secrets in endocrinology, enabling you to quickly review essential material. Uses a two-color page layout that makes reference easier. Features a convenient pocket size for easy access to key information. Features updates throughout to provide you with a current overview of the field of endocrinology. Includes the contributions of new authors who present the latest perspectives.
Rutter’s Child and Adolescent Psychiatry has become an established and accepted textbook of child psychiatry. Now completely revised and updated, the fifth edition provides a coherent appraisal of the current state of the field to help trainee and practising clinicians in their daily work. It is distinctive in being both interdisciplinary and international, in its integration of science and clinical practice, and in its practical discussion of how researchers and practitioners need to think about conflicting or uncertain findings. This new edition now offers an entirely new section on conceptual approaches, and several new chapters, including: neurochemistry and basic pharmacology brain imaging health economics psychopathology in refugees and asylum seekers bipolar disorder attachment disorders statistical methods for clinicians This leading textbook provides an accurate and comprehensive account of current knowledge, through the integration of empirical findings with clinical experience and practice, and is essential reading for professionals working in the field of child and adolescent mental health, and clinicians working in general practice and community pediatric settings.
This new edition provides an up-to-date coverage of important theoretical models in the scheduling literature as well as significant scheduling problems that occur in the real world. It again includes supplementary material in the form of slide-shows from industry and movies that show implementations of scheduling systems. The main structure of the book as per previous edition consists of three parts. The first part focuses on deterministic scheduling and the related combinatorial problems. The second part covers probabilistic scheduling models; in this part it is assumed that processing times and other problem data are random and not known in advance. The third part deals with scheduling in practice; it covers heuristics that are popular with practitioners and discusses system design and implementation issues. All three parts of this new edition have been revamped and streamlined. The references have been made completely up-to-date. Theoreticians and practitioners alike will find this book of interest. Graduate students in operations management, operations research, industrial engineering, and computer science will find the book an accessible and invaluable resource. Scheduling - Theory, Algorithms, and Systems will serve as an essential reference for professionals working on scheduling problems in manufacturing, services, and other environments.
Uncertainty in Policy Making explores how uncertainty is interpreted and used by policy makers, experts and politicians. It argues that conventional notions of rational, evidence-based policy making - hailed by governments and organisations across the world as the only way to make good policy - is an impossible aim in highly complex and uncertain environments; the blind pursuit of such a 'rational' goal is in fact irrational in a world of competing values and interests. The book centres around two high-profile and important case studies: the Iraq war and climate change policy in the US, UK and Australia. Based on three years' research, including interviews with experts such as Hans Blix, Paul Pillar, and Brian Jones, these two case studies show that the treatment of uncertainty issues in specialist advice is largely determined by how well the advice fits with or contradicts the policy goals and orientation of the policy elite. Instead of allowing the debates to be side-tracked by arguments over whose science or expert advice is 'more right', we must accept that uncertainty in complex issues is unavoidable and recognise the values and interests that lie at the heart of the issues. The book offers a 'hedging' approach which will enable policy makers to manage rather than eliminate uncertainty.
Beginning their study in the pre-Confederation period, the authors tell of the dramatic transformations that have characterized Canadian attitudes towards immigrants. While, at first, few obstacles were placed in the way of newcomers to Canada, the turn of the century brought policies of increasing selectivity.
Few areas of biomedical research provide greater opportunities to capitalize upon the revolution in genomics and molecular biology than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy in the Brain: From Bench to Bedside represents the definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped to create the field as well as those who are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects which would be of interest to anyone who is currently using or contemplating exploring gene therapy for neurobiological applications. Basic gene transfer technologies are discussed, with particular emphases upon novel vehicles, immunological issues and the role of gene therapy in stem cells. Numerous research applications are reviewed, particularly in complex fields such as behavioral neurobiology. Several preclinical areas are also covered which are likely to translate into clinical studies in the near future, including epilepsy, pain and amyotrophic lateral sclerosis. Among the most exciting advances in recent years has been the use of neurological gene therapy in human clinical trials, including Parkinson's disease, Canavan disease and Batten disease. Finally, readers will find "insider" information on technological and regulatory issues which can often limit effective translation of even the most promising idea into clinical use. This work provides up-to-date information and key insights into those gene therapy issues which are important to both scientists and clinicians focusing upon the brain and central nervous system.
Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. A full Solutions Manual is also available online for qualified instructors, to support teaching. - Winner, 2018 Textbook Excellence Award (Texty) from the Textbook and Academic Authors Association - Fully revised and updated throughout, and organized into 19 chapters for a more cogent and versatile presentation of concepts - Includes reaction examples taken from literature research reported between 2010-2015 - Features new full-color art and new chapter content on process chemistry and green organic chemistry - Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Solutions Manual for qualified course instructors
Fully updated, now in full color, this latest edition of Levin and O'Neal's The Diabetic Foot continues the work's proud tradition of providing the best diagnostic and management information for the challenging problems faced by patients with diabetic foot problems. With tips and pearls in every chapter, expansive color photographs, and its focus on team care, this classic reference is a must-have for anyone who cares for diabetic patients! Provide balanced, coordinated "team" care with multidisciplinary perspectives from diverse health professionals who care for diabetic patients with foot problems, including orthopedists, endocrinologists, vascular surgeons, podiatrists and wound care nurses. Use the exclusive Tips and Pearls in every chapter for quick review. Enjoy fresh takes on many topics with 50% new contributors. Find information more easily with a new full-color page design. Meet diagnostic challenges with color photographs of the clinical problems discussed in the book.
Now available in paperback and with over 10,000 entries, the Oxford Dictionary of Music (previously the Concise Oxford Dictionary of Music) offers broad coverage of a wide range of musical categories spanning many eras, including composers, librettists, singers, orchestras, important ballets and operas, and musical instruments and their history. The Oxford Dictionary of Music is the most up-to-date and accessible dictionaryof musical terms available and an essential point of reference for music students, teachers, lecturers, professional musicians, as well as music enthusiasts.
Convert the latest genomic data to the most effective patient management and treatment approaches Clinical Genomics helps healthcare providers translate the vast amount of new genomic data into successful clinical application. It is a comprehensive textbook and practical guide to the use of this information across a broad spectrum of adult diseases – from individual differences in drug responses, cardiac andcancer risks to Alzheimer's and other neurological and psychiatric disorders. While traditional textbooks on medical genetics focus on classic Mendelian disorders, Clinical Genomics discusses the everyday application of genetic assessment and the diagnostic, therapeutic, and preventiveimplications to the most common adult diseases that healthcare providers encounter. Covering approximately 200 conditions, it is a true clinical text for use across all of internal medicine. Coverage of each condition is presented in a consistent,clinically relevant manner and includes: Key Points Diagnostic Criteria and Clinical Characteristics Screening and C ounseling Management and Treatment Molecular Genetics and Molecular Mechanism Supplementary Information More than ten valuable appendices, include Genetic Privacy; Race, Ancestry, and Genetics; Personalized Medicine in Clinical Practice; Clinical Interpretationof Genomic Data; and Genetic Risk Profiling in the Genomics Era. Clinical Genomics is essential for internists, primary care physicians, and other healthcare providers who wish to increase their knowledge of the gene-and-protein level care of patients in a clinical setting.
Turn to the field's definitive text for a thoroughunderstanding of the clinical and scientific aspects of pulmonary medicine Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with 270 contributing authors, includes over 2,000 illustrations, 60 videos, and 18,000 references. The book opens with a comprehensive overview of the scientific basis of lung function in health and disease. It then provides detailed coverage of the broad array of diseases and disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms,respiratory infections, and respiratory failure, among others. The Fifth Edition has been completely updated to reflect the many advancements that have been made in pulmonary medicine over the past few years, including: Molecular development of the lung Stem cells and respiratory disease Genetics of pulmonary disease and the growth of personalized medicine Technical advances in lung transplantation Growth in immunology and immunosuppressive management Diagnosis and treatment of pulmonary hypertension Circadian rhythms and sleep biology Rapid evolution in lung imaging techniques, including functional imaging Contemporary interventional bronchoscopic techniques You will also find state-of-the-art coverage of thelatest topics in critical care medicine, including: Early diagnosis and management of sepsis Multiple organ dysfunction syndrome (MODS) Acute respiratory distress syndrome (ARDS) Management of agitation and delirium in the ICU The newly defined entity of "chronic critical illness
The best edition yet of the cornerstone text on abdominal operations—enhanced by thousands of full-color photographs and illustrations and thoroughly updated content A Doody’s Core Title for 2021! Edition after edition, Maingot’s Abdominal Operations has been hailed as the most complete, current, and trusted resource among general, colorectal, and gastrointestinal surgeons. Presented in full color, this classic textbook carefully details common and important abdominal procedures, offering a concise, yet complete, survey of the diagnosis and management of benign and malignant digestive disorders. Bolstered by more than 650 photographs and 1,250 full color illustrations, Maingot’s 78 chapters deliver everything you need to understand congenital, acquired, and neoplastic disorders – and optimize surgical outcomes for any type of abdominal disorder. FEATURES: Contemporary focus on operative procedures, and new concepts in the diagnosis and management of abdominal disease Convenient organ/procedure presentation provides a seamless review of surgical protocols, as well as pre- and postoperative strategies and techniques Added chapters on quality metrics, ERAS, and robotic surgery; and an increased number of “Perspective” commentaries by experts in the field Disease-focused and organ/procedure presentation provides a seamless review of surgical protocols, as well as pre- and postoperative strategies and techniques More than 650 photographs and 1,250 full color illustrations, many new to this edition
The definitive survey of diagnostic dermatopathology—and the single-best resource for addressing differential diagnosis at the microscopic level A Doody's Core Title for 2023 & 2024! For virtually every kind of skin lesion, this skill-sharpening resource has everything clinicians need to successfully perform differential diagnosis at the microscopic level. Barnhill's Dermatopathology features a systematic, algorithmic approach that cuts through the complexity of the discipline’s traditional disease-oriented focus, providing a ready-to-use diagnostic tool that puts the entire world of dermatopathology into perspective. This classic has won acclaim as the only dermatology pathology resource that is valuable for both teaching and for clinical practice and differential diagnosis. While other references may be more exhaustive, denser, or larger, none are more clinically useful as Barnhill's Dermatopathology. With 15% of the dermatology board and recertification examination consisting of dermatopathology topics, this is also an outstanding board review tool. Filled with hundreds of color photomicrographs, the book features a clear five-part organization and nearly forty detailed chapters—each reflecting the scientifically rigorous, up-to-date insights of authors who are acknowledged experts in the field. The book’s vast scope encompasses all skin disease processes—inflammatory, non-inflammatory, infections, and proliferations (harmatomas, hyperplasias, and neoplasms, plus disorders of nails and oral mucosa). Includes Online Bonus Content Increased number of full-color images Numerous tables assist clinicians differentiate similar conditions from one another NEW CHAPTERS on laboratory methods and stains, and updated immunohistochemistry content
THE DEFINITIVE ILLUSTRATED GUIDE TO ABDOMINAL OPERATIONS FOR GENERAL, COLORECTAL, AND GASTROINTESTINAL SURGEONS--NOW IN FULL COLOR! With each edition, Maingot's Abdominal Operations has built a legacy of expertise, currency, and clinical rigor acclaimed by surgical trainees and practicing surgeons. Presented in full-color for the first time, the 63 streamlined chapters of the twelfth edition offer a concise, yet complete, survey of the diagnosis and management of benign and malignant digestive diseases. This authoritative resource has everything you need to understand congenital, acquired, and neoplastic disorders--and optimize surgical outcomes for any type of abdominal procedure. FEATURES Contemporary focus on operative procedures, and new concepts in the diagnosis and management of abdominal disease Convenient organ/procedure presentation provides a seamless review of surgical protocols, as well as pre- and postoperative strategies and techniques Thirteen new "Perspective" chapters feature expert commentary and alternative viewpoints on the most clinically relevant topics Added chapters on gastrointestinal bleeding, abdominal trauma, and abdominal vascular emergencies--along with minimally invasive surgery chapters woven throughout the text--present current, ready-to-use insights designed to enhance surgical care and recovery More than 1,250 illustrations (most in full color)
A Doody's Core Title for 2023! The #1 Textbook in Pharmacotherapy providing optimal patient outcomes using evidence-based medication therapies—updated with the latest advances and guidelines For more than 30 years, DiPiro’s Pharmacotherapy has been the essential textbook for learning how to properly select, administer, and monitor drugs―everything needed to provide safe, effective drug therapy across all therapeutic categories. This new edition has been fully updated with the latest evidence-based information and recommendations. With content from 300 expert contributors, this valuable resource offers detailed descriptions of common and uncommon disease states, including treatment by pharmacologic and non-pharmacologic means. Each disease chapter opens with a Patient Care Process, helping readers understand the collaborative care model in which pharmacists work and communicate with other healthcare providers for effective coordinated care. Here's why DiPiro's Pharmacotherapy: A Pathophysiologic Approach is the perfect learning tool for students, pharmacists, and other healthcare providers: All chapters provide the most current, reliable, and relevant information available Key concepts are included at the beginning of each chapter Clinical Presentation boxes concisely outline disease signs and symptoms New: Beyond the Book feature points readers to multimedia resources to deepen their understanding of the material Diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches clearly distinguish treatment pathways New: Drug monitoring tables have been added Patient care process boxes help readers know how to communicate with other health care providers New: Additional FREE E-Chapters are available on AccessPharmacy New: Over 2000 Review Questions to help prepare students!
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