The true story of US Marine Corporal Jason Dunham's brave act that saved fellow Marines and earned him the Congressional Medal of Honor. Corporal Dunham was on patrol near the Syrian border, on April 14, 2004, when a black-clad Iraqi leaped out of a car and grabbed him around his neck. Fighting hand-to-hand in the dirt, Dunham saw his attacker drop a grenade and made the instantaneous decision to place his own helmet over the explosive in the hope of containing the blast and protecting his men. When the smoke cleared, Dunham’s helmet was in shreds, and the corporal lay face down in his own blood. The Marines beside him were seriously wounded. Dunham was subsequently nominated for the Congressional Medal of Honor, the nation’ s highest award for military valor. Phillips’s minute-by-minute chronicle of the chaotic fighting that raged throughout the area and culminated in Dunham’s injury provides a grunt’s-eye view of war as it’s being fought today—fear, confusion, bravery, and suffering set against a brotherhood forged in combat. His account of Dunham’s eight-day journey home and of his parents’ heartrending reunion with their son powerfully illustrates the cold brutality of war and the fragile humanity of those who fight it. Dunham leaves an indelible mark upon all who know his story, from the doctors and nurses who treat him, to the readers of the original Wall Street Journal article that told of his singular act of valor.
A well-illustrated and comprehensive analysis of the treatment of diabetic retinopathy, this book covers current treatment options and guidelines, whilst also providing a detailed discussion of emerging therapeutic targets. Existing therapeutic options are covered in depth, with a major focus on anti-vascular endothelial growth factor drugs and sustained release corticosteroids, including a review of trial results supporting current treatment guidelines. The use of agents off-label is also discussed. Controversial topics are discussed in detail with an emphasis on helping the reader make informed decisions, particularly when treating patients for which several treatment approaches may be appropriate because trial data does not clearly define the best option. Emerging therapeutic areas are evaluated, as work continues to identify agents that produce superior morphologic responses and visual acuity gains by targeting other molecules that contribute to diabetic retinopathy. Promising new drugs, targets and delivery systems are identified, and their development analysed.
Seismic waves - generated both by natural earthquakes and by man-made sources - have produced an enormous amount of information about the Earth's interior. In classical seismology, the Earth is modeled as a sequence of uniform horizontal layers (or spherical shells) having different elastic properties and one determines these properties from travel times and dispersion of seismic waves. The Earth, however, is not made of horizontally uniform layers, and classic seismic methods can take large-scale inhomogeneities into account. Smaller-scale irregularities, on the other hand, require other methods. Observations of continuous wave trains that follow classic direct S waves, known as coda waves, have shown that there are heterogeneities of random size scattered randomly throughout the layers of the classic seismic model. This book focuses on recent developments in the area of seismic wave propagation and scattering through the randomly heterogeneous structure of the Earth, with emphasis on the lithosphere. The presentation combines information from many sources to present a coherent introduction to the theory of scattering in acoustic and elastic materials and includes analyses of observations using the theoretical methods developed. The second edition especially includes new observational facts such as the spatial variation of medium inhomogeneities and the temporal change in scattering characteristics and recent theoretical developments in the envelope synthesis in random media for the last ten years. Mathematics is thoroughly rewritten for improving the readability. Written for advanced undergraduates or beginning graduate students of geophysics or planetary sciences, this book should also be of interest to civil engineers, seismologists, acoustical engineers, and others interested in wave propagation through inhomogeneous elastic media.
Is it possible to learn something without being aware of it? How does emotion influence the way we think? How can we improve our memory? Fundamentals of Cognition, third edition, provides a basic, reader-friendly introduction to the key cognitive processes we use to interact successfully with the world around us. Our abilities in attention, perception, learning, memory, language, problem solving, thinking, and reasoning are all vitally important in enabling us to cope with everyday life. Understanding these processes through the study of cognitive psychology is essential for understanding human behaviour. This edition has been thoroughly updated and revised with an emphasis on making it even more accessible to introductory-level students. Bringing on board Professor Marc Brysbaert, a world-leading researcher in the psychology of language, as co-author, this new edition includes: developed and extended research activities and "In the Real World" case studies to make it easy for students to engage with the material; new real-world topics such as discussions of attention-deficit/hyperactivity disorder, the reading problems of individuals with dyslexia, why magic tricks work, and why we cannot remember the Apple logo accurately; a supporting companion website containing multiple choice questions, flashcards, sample essay answers, instructor resources, and more. The book provides a perfect balance between traditional approaches to cognition and cutting-edge cognitive neuroscience and cognitive neuropsychology. Covering all the key topics within cognition, this comprehensive overview is essential reading for all students of cognitive psychology and related areas such as clinical psychology.
Pinedo is a major figure in the scheduling area (well versed in both stochastics and combinatorics) , and knows both the academic and practitioner side of the discipline. This book includes the integration of case studies into the text. It will appeal to engineering and business students interested in operations research.
This book advances an alternative reading of the social, political and cultural issues surrounding schools and technology and develops a comprehensive overview of the interplay between policy, practice and identity in school workplaces. It explores how digital technologies have become an integral element of the politics and socially negotiated practices of school workplaces as school campuses are now awash with digital hardware and growing amounts of school work is carried out on a 'virtual' basis.
Drs. John C. Perkins and Michael E. Winters have assembled an expert team of authors on the topic of Sepsis in the Emergency Department. Article topics include: Defining and Diagnosing Sepsis; Appropriate Antibiotic Therapy; Severe Sepsis Resuscitation in Resource Limited Settings; Source Control in Severe Sepsis; Considerations in Special Populations with Severe Sepsis; Pediatric Severe Sepsis Resuscitation; The New Usual Care; Prehospital Sepsis Care; Endpoints of Sepsis Resuscitation; Pitfalls in the Diagnosis, Treatment, and Disposition of Severe Sepsis; Biomarkers in Sepsis; Vasopressors and Inotropes in Sepsis; and Sepsis Quality Measures and Performance Improvement.
This text provides an innovative new framework for the formative and holistic assessment of students' digital writing. It also addresses the rapid evolution of writing assessment tools, analyzing the research in clear terms for both techno-phobic and techno-savvy teachers. The author critiques computer automated scoring of student writing, for example, but also considers the possibilities and potential of the future of technology assisted assessments.
Based on the most current evidence and best practices, Perioperative Medicine: Managing for Outcome, 2nd Edition, is an easy-to-follow, authoritative guide to achieving optimal outcomes in perioperative care. Written and edited by recognized authorities in anesthesiology and surgical critical care, this fully updated edition helps you think critically about complex, long-term issues surrounding the care of the surgical patient, providing decision trees that define strategies to enhance the medical outcome of care. - Focuses on what anesthesiologists, surgeons, and intensivists need to know in order to improve outcomes through evidence- and outcome-based approaches. - Provides practical guidance on potential risks to all major organ systems, the etiology of particular organ dysfunctions, preoperative and intraoperative risk factors, and perioperative protection strategies to minimize potential complications. - Features a consistent chapter format - with even more color-coded algorithms, summary tables, and boxes – that enables you to quickly explore and determine the best management approaches. - Includes six all-new chapters: Perioperative Fluid Management; Delirium and POCD; Role of Palliative Care/ICU; Value-Based Care: The UK Model; CFO Perspective on Value; Hospital to Home (Perioperative Transitions of Care) - Discusses timely topics such as quality improvement, pay-for-performance, preexisting disease and comorbid conditions in anesthesiology, and the team-based model of care. - Features two new editors, surgeon Clifford Ko, MD, and Perioperative Summit leader, Michael (Monty) Mythen, MD.
This book focuses on planning and scheduling applications. Planning and scheduling are forms of decision-making that play an important role in most manufacturing and services industries. The planning and scheduling functions in a company typically use analytical techniques and heuristic methods to allocate its limited resources to the activities that have to be done. The application areas considered in this book are divided into manufacturing applications and services applications. The book covers five areas in manufacturing: project scheduling, job shop scheduling, scheduling of flexible assembly systems, economic lot scheduling, and planning and scheduling in supply chains. It covers four areas in services: reservations and timetabling, tournament scheduling, planning and scheduling in transportation, and workforce scheduling. At the end of each chapter, a case study or a system implementation is described in detail. Numerous examples and exercises throughout the book illustrate the material presented. The fundamentals concerning the methodologies used in the application chapters are covered in the appendices. The book comes with a CD-ROM that contains various sets of powerpoint slides. The CD also contains several planning and scheduling systems that have been developed in academia as well as generic optimization software that has been developed in industry. This book is suitable for more advanced students in industrial engineering and operations research as well as graduate students in business. Michael Pinedo is the Julius Schlesinger Professor of Operations Management in the Stern School of Business at New York University. His research interests lie in the theoretical and applied aspects of planning and scheduling. He has written numerous papers on the theory of deterministic and stochastic scheduling and has also consulted extensively in industry. He has been actively involved in the development of several large industrial planning and scheduling systems.
Discusses three major classes of asthma therapies-bronchodilators, antiinflammatories, and antiallergics-as well as potential new therapeutic approaches! This comprehensive volume addresses the latest treatment strategies for asthma, keying in on the genetics and molecular biology of asthma and pointing the way toward new, commercially viable therapies. Presents the most up-to-date information available on the genetics, epidemiology, pathology, pharmacology, and pulmonology of asthma. Written by more than 20 leading international experts, New and Exploratory Therapeutic Agents for Asthma explores asthma both as incidence of dysfunctional airway smooth muscle and as a disorder of the immune system examines the role of monoclonal antibodies in allergy and asthma describes functions and pharmacokinetic profiles of bronchodilator 2 agonists, anticholinergics, and inhaled glucocorticosteroids investigates the controversy of different types of asthma illustrates the connections between clinical symptoms and the immunopathology of eosinophilic inflammation assesses prospects for the development of a successful oral anti-inflammatory therapy, an immunomodulator that lowers antigen-specific IgE, an anticytokine compound, and an agent that safely combines bronchospasmolytic and anti-inflammatory properties reviews the impact of the recent introduction of antileukotriene agents, clinical findings with PAF antagonists, and selective antimuscarinics evaluates the relationship between improvements in laboratory results and clinical effectiveness and more! Containing over 2000 bibliographic citations and a concise introduction for each chapter, New and Exploratory Therapeutic Agents for Asthma is indispensable for pulmonologists, pediatricians, physiologists, immunologists, allergists, pharmaceutical industry scientists, primary care physicians, and medical school students in these disciplines.
The popular introduction to the genomic revolution for non-scientists—the revised and updated new edition Welcome to the Genome is an accessible, up-to-date introduction to genomics—the interdisciplinary field of biology focused on the structure, function, evolution, mapping, and editing of an organism's complete set of DNA. Written for non-experts, this user-friendly book explains how genomes are sequenced and explores the discoveries and challenges of this revolutionary technology. Genomics is a mixture of many fields, including not only biology, engineering, computer science, and mathematics, but also social sciences and humanities. This unique guide addresses both the science of genomics and the ethical, moral, and social questions that rise from the technology. There have been many exciting developments in genomics since this book's first publication. Accordingly, the second edition of Welcome to the Genome offers substantial new and updated content to reflect recent major advances in genome-level sequencing and analysis, and demonstrates the vast increase in biological knowledge over the past decade. New sections cover next-generation technologies such as Illumina and PacBio sequencing, while expanded chapters discuss controversial ethical and philosophical issues raised by genomic technology, such as direct-to-consumer genetic testing. An essential resource for understanding the still-evolving genomic revolution, this book: Introduces non-scientists to basic molecular principles and illustrates how they are shaping the genomic revolution in medicine, biology, and conservation biology Explores a wide range of topics within the field such as genetic diversity, genome structure, genetic cloning, forensic genetics, and more Includes full-color illustrations and topical examples Presents material in an accessible, user-friendly style, requiring no expertise in genomics Discusses past discoveries, current research, and future possibilities in the field Sponsored by the American Museum of Natural History, Welcome to the Genome: A User's Guide to the Genetic Past, Present, and Future is a must-read book for anyone interested in the scientific foundation for understanding the development and evolutionary heritage of all life.
This book explores how different publics make sense of and evaluate anti-terrorism powers within the UK, and the implications of this for citizenship and security. Drawing on primary empirical research, the book argues that whilst white individuals are not unconcerned about the effects of anti-terrorism, ethnic minority citizens (including, but not only those identifying as Muslim) believe that anti-terrorism powers have impacted negatively on their citizenship and security. This book thus offers the first systematic engagement with ‘vernacular’ or ‘everyday’ understandings of anti-terrorism policy, citizenship and security. It argues that while transformations in anti-terrorism frameworks impact on public experiences of security and citizenship, they do not do so in a uniform, homogeneous, or predictable manner. At the same time, public understandings and expectations of security and citizenship themselves shape how developments in anti-terrorism frameworks are discussed and evaluated. This important new book will be of interest to researchers and students working in a wide range of disciplines including Political Science, International Relations, Security Studies and Sociology.
Previous editions have established this best-selling student handbook as THE cognitive psychology textbook of choice, both for its academic rigour and its accessibility. This sixth edition continues this tradition. It has been substantially updated and revised to reflect new developments in the field (especially within cognitive neuroscience). Traditional approaches are combined with the cutting-edge cognitive neuroscience approach to create a comprehensive, coherent and totally up-to-date overview of all the main fields in cognitive psychology. The major topics covered include perception, attention, memory, concepts, language, problem solving, and reasoning, as well as some applied topics such as everyday memory. New to this edition: Presented in full-colour throughout, with numerous colour illustrations including photographs and brain scans Increased emphasis on cognitive neuroscience, to reflect its growing influence on cognitive psychology A NEW chapter on Cognition and Emotion A WHOLE chapter on Consciousness Increased coverage of applied topics such as recovered memories, medical expertise, informal reasoning, and emotion regulation incorporated throughout the textbook More focus on individual differences in areas including long-term memory, expertise, reasoning, emotion and regulation. The textbook is packed full of useful features that will engage students and aid revision, including key terms, which are new to this edition, chapter summaries, and suggestions for further reading. Written by one of the leading textbook authors in psychology, this thorough and user-friendly textbook will continue to be essential reading for all undergraduate students of psychology. Those taking courses in computer science, education, linguistics, physiology, and medicine will also find it an invaluable resource. This edition is accompanied by a rich array of supplementary materials, which will be made available to qualifying adopters completely free of charge. The online multimedia materials include: A PowerPoint lecture course and multiple-choice question test bank A unique Student Learning Program: an interactive revision program incorporating a range of multimedia resources including interactive exercises and demonstrations, and active reference links to journal articles.
AIDS treatments continues to evolve. Now, so does the definitive reference on this complex and challenging subject! "AIDS Therapy, 3rd Edition" not only brings you comprehensive guidance on the latest treatments for HIV/AIDS and the full range of related disorders and syndromes, but also comes with access to updates online—so you can always tap into the most current therapy guidelines. Written by a "who's who" of leading global experts, the new edition of this classic reference is a must for any clinician who manages patients with HIV/AIDS. The most comprehensive coverage available on AIDS treatment equips you to meet any clinical challenge. Contributions from a large cast of noted international authorities put global "best practices" at your fingertips. Advice from some of the most respected experts in the field helps you manage your patients confidently. Available with a companion website allowing you to access the latest treatment guidelines year after year.
This is the master volume to the 28 book set on Irish Family History from the Irish Genealogical Foundation. The largest and most comprehensive of the series, this volume includes family histories from every county in Ireland and Northern Ireland. It also has, for the first time, the complete surname index for the entire series. The 27 other books which are indexed in this volume will provide additional information on even more families.
An introduction to contemporary rural societies and economies in the developed world, 'Rural Geography' examines the social and economic processes at work in the contemporary countryside.
This best-selling textbook presents a comprehensive and accessible overview of the study of memory. Written by three of the world’s leading researchers in the field, it contains everything the student needs to know about the scientific approach to memory and its applications. Each chapter of the book is written by one of the three authors, an approach which takes full advantage of their individual expertise and style, creating a more personal and accessible text. This enhances students’ enjoyment of the book, allowing them to share the authors’ own fascination with human memory. The book also draws on a wealth of real-world examples throughout, showing students exactly how they can relate science to their everyday experiences of memory. Key features of this edition: Thoroughly revised throughout to include the latest research and updated coverage of key ideas and models A brand new chapter on Memory and the Brain, designed to give students a solid understanding of methods being used to study the relationship between memory and the brain, as well as the neurobiological basis of memory Additional pedagogical features to help students engage with the material, including many ‘try this’ demonstrations, points for discussion, and bullet-pointed chapter summaries The book is supported by a companion website featuring extensive online resources for students and lecturers.
In its first edition, Soils established itself as the leading textbook in the fields of pedology and soil geomorphology. Expanded and fully updated, this second edition maintains its highly organized and readable style. Suitable as a textbook and a research-grade reference, the book's introductory chapters in soil morphology, mineralogy, chemistry, physics and organisms prepare the reader for the more advanced treatment that follows. Unlike its competitors, this textbook devotes considerable space to discussions of soil parent materials and soil mixing, along with dating and paleoenvironmental reconstruction techniques applicable to soils. Although introductions to widely used soil classification systems are included, theory and processes of soil genesis and geomorphology form the backbone of the book. Replete with more than 550 high-quality figures and photos and a detailed glossary, this book will be invaluable for anyone studying soils, landforms and landscape change anywhere on the globe.
This book analyzes revenue management (RM) problems with flexible products and RM in broadcasting companies. It presents models and methods that explicitly take the implications of flexibility into account. In addition, it contains descriptions of algorithms to generate stochastic demand data streams for general RM problems. To help readers with their own simulation studies, it provides an implementation as a Microsoft Windows executable file.
Discover how the latest computational tools are building our understanding of particle interactions and leading to new applications With this book as their guide, readers will gain a new appreciation of the critical role that particle interactions play in advancing research and developing new applications in the biological sciences, chemical engineering, toxicology, medicine, and manufacturing technology The book explores particles ranging in size from cations to whole cells to tissues and processed materials. A focus on recreating complex, real-world dynamical systems helps readers gain a deeper understanding of cell and tissue mechanics, theoretical aspects of multiscale modeling, and the latest applications in biology and nanotechnology. Following an introductory chapter, Multiscale Modeling of Particle Interactions is divided into two parts: Part I, Applications in Nanotechnology, covers: Multiscale modeling of nanoscale aggregation phenomena: applications in semiconductor materials processing Multiscale modeling of rare events in self-assembled systems Continuum description of atomic sheets Coulombic dragging and mechanical propelling of molecules in nanofluidic systems Molecular dynamics modeling of nanodroplets and nanoparticles Modeling the interactions between compliant microcapsules and patterned surfaces Part II, Applications in Biology, covers: Coarse-grained and multiscale simulations of lipid bilayers Stochastic approach to biochemical kinetics In silico modeling of angiogenesis at multiple scales Large-scale simulation of blood flow in microvessels Molecular to multicellular deformation during adhesion of immune cells under flow Each article was contributed by one or more leading experts and pioneers in the field. All readers, from chemists and biologists to engineers and students, will gain new insights into how the latest tools in computational science can improve our understanding of particle interactions and support the development of novel applications across the broad spectrum of disciplines in biology and nanotechnology.
This is the first book to present a model, based on rational mechanics of electrorheological fluids, that takes into account the complex interactions between the electromagnetic fields and the moving liquid. Several constitutive relations for the Cauchy stress tensor are discussed. The main part of the book is devoted to a mathematical investigation of a model possessing shear-dependent viscosities, proving the existence and uniqueness of weak and strong solutions for the steady and the unsteady case. The PDS systems investigated possess so-called non-standard growth conditions. Existence results for elliptic systems with non-standard growth conditions and with a nontrivial nonlinear r.h.s. and the first ever results for parabolic systems with a non-standard growth conditions are given for the first time. Written for advanced graduate students, as well as for researchers in the field, the discussion of both the modeling and the mathematics is self-contained.
Grasses are the world’s most important plants. They are the dominant species over large parts of the earth’s land surface, a fact that is reflected in the many different words that exist for grasslands, words such as prairie, veldt, palouse, and pampas to mention just a few. As a group, grasses are of major ecological importance, as soil binders and providers of shelter and food for wild animals, both large and small. Some grasses, such as wheat, rice, corn, barley, rye, tef, and sugar cane are major sources of calories for humans and their livestock; others, primarily bamboos, are used for construction, tools, paper, and fabric. More recently, the seed catalogs that tantalize gardeners each winter have borne witness to an increasing appreciation of the aesthetic value of grasses. The Manual of Grasses for North America is designed as a successor to the classic volume by Hitchcock and Chase. It reflects current taxonomic thought and includes keys, illustrations, and distribution maps for the nearly 900 native and 400 introduced species that have been found in North America north of Mexico. In addition, it presents keys and illustrations for several species that are known only in cultivation or are of major agricultural significance, either as progenitors of bread wheat and corn or as a major threat to North American agriculture because of their ability to hybridize with crop species. The Manual of Grasses for North America is a major reference work for grasses that will retain its value for many years.
Rural issues have gained national prominence in Britain in recent years. The future of hunting, the Foot and Mouth outbreak, farm income and agricultural reform and housing development have all claimed political and media attention, promoted by a vocal rural lobby and headline-grabbing protests and demonstrations. Combining detailed empirical research and case studies with theoretically informed critical analysis, this book provides an overview of the contemporary politics of the British countryside. It explores how and why rural issues have suddenly achieved such political prominence, by examining the changing politics and governance of rural Britain from the local to the national scale over the past century. It investigates the social, economic and institutional restructuring of rural communities and argues that we are witnessing not so much a rural politics, but a 'politics of the rural' in which the definition and representation of rurality itself has become the key focus of conflict.
Recognized as the most prestigious, comprehensive text on Global Health for GRADUATE programs in public and global health. Global Health, Third Edition (formerly titled International Public Health) brings together contributions from the world's leading authorities into a single comprehensive text. It thoroughly examines the wide range of global health challenges facing low and middle income countries today and the various approaches nations adopt to deal with them. These challenges include measurement of health status, infectious and chronic diseases, injuries, nutrition, reproductive health, global environmental health and complex emergencies. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
Climate change is the single most important global environmental and development issue facing the world today and has emerged as a major topic in tourism studies. Climate change is already affecting the tourism industry and is anticipated to have profound implications for tourism in the twenty-first century, including consumer holiday choices, the geographic patterns of tourism demand, the competitiveness and sustainability of destinations and the contribution of tourism to international development. Tourism and Climate Change: Impacts, Adaptation and Mitigation is the first book to provide a comprehensive overview of the theory and practice of climate change and tourism at the tourist, enterprise, destination and global scales. Major themes include the implications of climate change and climate policy for tourism sectors and destinations around the world, tourist perceptions of climate change impacts, tourism’s global contribution to climate change, adaptation and mitigation responses by all major tourism stakeholders, and the integral links between climate change and sustainable tourism. It combines a thorough scientific assessment of the climate-tourism interrelationships with discussion of emerging mitigation and adaptation practice, showcasing international examples throughout the tourism sector as well as actions by other sectors that will have important implications for tourism. Written by three leading academics in this field, this critical contribution highlights the challenges of climate change within the tourism community and provides a foundation for decision making for both reducing the risks, and taking advantage of the opportunities, associated with climate change. This comprehensive discussion of the complexities of climate change and tourism is essential reading for students, academics, business leaders and government policy makers.
A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Alcohol, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. - Outlines the history and behavioral mechanism of action of alcohol relevant to the neurobiology of alcohol addiction - Includes neurocircuitry, cellular, and molecular neurobiological mechanisms of alcohol addiction in each stage of the addiction cycle - Explores evolving areas of research associated with all three stages of the alcohol addiction cycle, including neurobiological studies of neurodevelopmental effects of early exposure to alcohol, sleep disturbances caused by alcohol, pain interactions with alcohol, sex differences in the response to alcohol, and epigenetic/genetic interactions with alcohol
The premier single-volume reference in the field of anesthesia, Clinical Anesthesia is now in its Sixth Edition, with thoroughly updated coverage, a new full-color design, and a revamped art program featuring 880 full-color illustrations. More than 80 leading experts cover every aspect of contemporary perioperative medicine in one comprehensive, clinically focused, clear, concise, and accessible volume. Two new editors, Michael Cahalan, MD and M. Christine Stock, MD, join Drs. Barash, Cullen, and Stoelting for this edition. A companion Website will offer the fully searchable text, plus access to enhanced podcasts that can be viewed on your desktop or downloaded to most Apple and BlackBerry devices. This is the tablet version which does not include access to the supplemental content mentioned in the text.
Fully revised, this second edition offers a proven strategy for using ambidexterity to build discontinuous growth for mature organizations, and the flexibility to adapt in fast-changing environments. Why do successful firms find it so difficult to adapt in the face of change – to innovate? In the past ten years, the importance of this question has increased as more industries and firms confront disruptive change. The pandemic has accelerated this crisis, collapsing the structures of industries from airlines and medicine to online retail and commercial real estate. Today, leaders in business have an obligation not only to investors but to their employees and communities. At the core of this challenge is helping their organizations to survive in the face of change. The original edition summarized the lessons that the authors as researchers and consultants had learned over the previous two decades. Since then, they have continued to work with leaders of organizations around the world confronting disruptive change. With updates to every chapter, including new examples and analysis, this fully revised edition incorporates the lessons and insights that the authors have gained in the past five years. Two new chapters critically examine the role of organizational culture in promoting or hindering ambidexterity and its underlying fundamental disciplines. Using examples from firms such as Microsoft, General Motors, and Amazon, O'Reilly and Tushman illustrate how leaders can align their organization's cultures to fit the needed strategy, and how ideation, incubation, and scaling approaches, when used altogether, can successfully develop new growth businesses.
A vital, timely text on the viruses that cause pandemics and how to face them, by the New York Times bestselling author of How Not to Die. As the world grapples with the devastating impact of COVID-19, Dr Michael Greger reveals not only what we can do to protect ourselves and our loved ones during a pandemic, but also what human society must rectify to reduce the likelihood of even worse catastrophes in the future. From tuberculosis to bird flu and HIV to coronavirus, these infectious diseases share a common origin story: human interaction with animals. Otherwise known as zoonotic diseases for their passage from animals to humans, these pathogens – both pre-existing ones and those newly identified – emerge and re-emerge throughout history, sparking epidemics and pandemics that have resulted in millions of deaths around the world. How did these diseases come about? And what – if anything – can we do to stop them and their fatal march into our countries, our homes, and our bodies? In How to Survive a Pandemic, Dr Michael Greger, physician and internationally-recognized expert on public health issues, delves into the origins of some of the deadliest pathogens the world has ever seen. Tracing their evolution from the past until today, Dr Greger spotlights emerging flu and coronaviruses as he examines where these pathogens originated, as well as the underlying conditions and significant human role that have exacerbated their lethal influence to large, and even global, levels.
In order to accurately describe and diagnose psychiatric illness, practitioners require in-depth knowledge of the signs and symptoms of behavioral disorders. Descriptive Psychopathology provides a broad review of the psychopathology of psychiatric illness, beyond the limitations of the DSM and ICD criteria. Beginning with a discussion of the background to psychiatric classification, the authors explore the problems and limitations of current diagnostic systems. The following chapters then present the principles of psychiatric examination and diagnosis, described with accompanying patient vignettes and summary tables, and related to different diagnostic concerns. A thought-provoking conclusion proposes a restructuring of psychiatric classification based on the psychopathology literature and its validating data. Written for psychiatry and neurology residents, clinical psychologists, behavioral neurologists, clinical psychology students and psychiatric nurse practitioners, it is invaluable to anyone who accepts the responsibility for the care of patients with behavioral syndromes.
Digital revolution demands new approaches to regulating work. The ‘Uberisation’ of work is not, in reality, a new phenomenon. It reintroduces the practices of ‘on-demand’ engagement of labour, common prior to the development of continuing employment. What is new, however, is the capacity of digital technology to engage labour in ways that avoid characterisation as employment according to the legal tests developed in the 20th century. This book tackles the challenge of ensuring that the emerging tribes of ‘gig’ workers in labour markets across the globe are afforded decent standards of work. This book discusses how to provide decent conditions and safe working standards for on-demand workers engaged through digital platforms. It interrogates the rise of gig work, and the legal strategies that might be engaged to deal with the risk that on-demand work will fall and remain outside of employment protections. It draws on observations of practices across the globe but focusses particularly on regulatory solutions developed in Australia. The book will be a useful reference to policy making and legal reforms to address vulnerabilities of gig workers.
Today, the Bay Area is home to the most successful knowledge economy in America, while Los Angeles has fallen progressively further behind its neighbor to the north and a number of other American metropolises. Yet, in 1970, experts would have predicted that L.A. would outpace San Francisco in population, income, economic power, and influence. The usual factors used to explain urban growth—luck, immigration, local economic policies, and the pool of skilled labor—do not account for the contrast between the two cities and their fates. So what does? The Rise and Fall of Urban Economies challenges many of the conventional notions about economic development and sheds new light on its workings. The authors argue that it is essential to understand the interactions of three major components—economic specialization, human capital formation, and institutional factors—to determine how well a regional economy will cope with new opportunities and challenges. Drawing on economics, sociology, political science, and geography, they argue that the economic development of metropolitan regions hinges on previously underexplored capacities for organizational change in firms, networks of people, and networks of leaders. By studying San Francisco and Los Angeles in unprecedented levels of depth, this book extracts lessons for the field of economic development studies and urban regions around the world.
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