A Timely Exploration of Multiuser Detection in Wireless Networks During the past decade, the design and development of current and emerging wireless systems have motivated many important advances in multiuser detection. This book fills an important need by providing a comprehensive overview of crucial recent developments that have occurred in this active research area. Each chapter is contributed by noted experts and is meant to serve as a self-contained treatment of the topic. Coverage includes: Linear and decision feedback methods Iterative multiuser detection and decoding Multiuser detection in the presence of channel impairments Performance analysis with random signatures and channels Joint detection methods for MIMO channels Interference avoidance methods at the transmitter Transmitter precoding methods for the MIMO downlink This book is an ideal entry point for exploring ongoing research in multiuser detection and for learning about the field's existing unsolved problems and issues. It is a valuable resource for researchers, engineers, and graduate students who are involved in the area of digital communications.
The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational challenges and opportunities that drug repositioning offers. Readers will learn how to perform the latest experimental and computational methods that support drug repositioning, and detailed case studies throughout the book demonstrate how these methods fit within the context of a comprehensive drug repositioning strategy. Drug Repositioning is divided into three parts: Part 1, Drug Repositioning: Business Case, Strategies, and Operational Considerations, examines the medical and commercial drivers underpinning the quest to reposition existing drugs, guiding readers through the key strategic, technical, operational, and regulatory decisions needed for successful drug repositioning programs. Part 2, Application of Technology Platforms to Uncover New Indications and Repurpose Existing Drugs, sets forth computational-based strategies, tools, and databases that have been designed for repositioning studies, screening approaches, including combinations of existing drugs, and a look at the development of chemically modified analogs of approved agents. Part 3, Academic and Non-Profit Initiatives & the Role of Alliances in the Drug Repositioning Industry, explores current investigations for repositioning drugs to treat rare and neglected diseases, which are frequently overlooked by for-profit pharmaceutical companies due to their lack of commercial return. The book's appendix provides valuable resources for drug repositioning researchers, including information on drug repositioning and reformulation companies, databases, government resources and organizations, regulatory agencies, and drug repositioning initiatives from academia and non-profits. With this book as their guide, students and pharmaceutical researchers can learn how to use drug repositioning techniques to extend the lifespan and applications of existing drugs as well as maximize the return on investment in drug research and development.
New York Construction Law covers everything from licensing and contracts to disputes and claims-including full chapters on design-build projects and recent trends in ADR. It examines all the pertinent cases and statutes, with expert analysis by the state's top construction attorneys, along with practical insights, warnings, and advice culled from years of experience. Highlights include: extensive discussion of the newly enacted Terrorism Risk Insurance Act of 2002 - burden of proof under the Eicheleay formula - pending legislation in New York that would permit a new form of business entity that would be know as design professional service corporation - efforts by Governor Pataki to repeal the Wick's Law - pending state legislation that would render design-build contracts void unless the licensed engineer or architect is specifically identified in the contract and such licensee's practice is independent of the contracting party's business - pending state legislation that would increase the threshold for public works contracts - latest cases concerning who may file a lien, what items are alienable, when liens can be filed, liens filed against condominiums, lien foreclosure actions - a new section regarding assignee of construction contracts.
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.