Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. A full Solutions Manual is also available online for qualified instructors, to support teaching. - Winner, 2018 Textbook Excellence Award (Texty) from the Textbook and Academic Authors Association - Fully revised and updated throughout, and organized into 19 chapters for a more cogent and versatile presentation of concepts - Includes reaction examples taken from literature research reported between 2010-2015 - Features new full-color art and new chapter content on process chemistry and green organic chemistry - Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Solutions Manual for qualified course instructors
With your heavy case load, you can't afford to waste time searching for answers. Cardiology, 3rd Edition, by Drs. Crawford, DiMarco, and Paulus, offers you just the practical, problem-based guidance you need to quickly overcome any clinical challenge. 8 color-coded sections cover the 8 major clinical syndromes of cardiovascular disease—each section a virtual "mini textbook" on its topic! 40 new chapters keep you up to date with the latest advances in the field, while more than 2,000 lavish, high-quality illustrations, color photographs, tables, and ECGs capture clinical manifestations as they present in practice. It’s current, actionable information that you can put to work immediately for your patients! Offers a problem-based approach that integrates basic science, diagnostic investigations, and therapeutic management in one place for each cardiovascular disease so you can quickly find all of the actionable knowledge you need without flipping from one section to another. Features introductory bulleted highlights in each chapter that present the most pertinent information at a glance. Presents abundant algorithms to expedite clinical decision making. Includes more than 2,000 lavish, high-quality illustrations, color photographs, tables, and ECGs that capture clinical manifestations as they present in practice, and promote readability and retention. Includes 40 new chapters including Inherited Arrhythmia Syndromes, Implantable Cardioverter-Defibrillators and Cardiac Resynchronization Therapy in CHD, Management of the Cyanotic Patient with CHD, Special Problems for the Cardiology Consultant Dealing with Bariatric/Gastric Bypass — and many more — that equip you with all of the latest knowledge. Presents "Special Problem" sections—many new to this edition—that provide practical advice on problems that can be difficult to treat.
One day, in a moment of weakness, I fell prey to the temptation to organize and edit this volume on the mechanism of insulin action. The major reason for attempting to resist, of course, is the amazing speed at which advances are being made in this field. The usefulness of books such as this is often quickly compromised by new findings obtained during and just after publication. Happily for the contributors to this volume and myself, this unfortunate fate does not appear to be in store for us. New and important findings will undoubtedly continue to flow in this field during the next few years, but I believe this will increase rather than decrease the usefulness of this volume. As a matter of fact, as we go to press, I am delighted both that I was tempted and that I failed to resist. There are two basic reasons for my enthusiasm about this book, and they both relate to this issue of timeliness. First, each of the contributors has had an opportunity to update the scientific content of the various chapters only a few months before actual publication of this volume. The material presented in this volume is, at publication, contemporary with the current original literature. This volume thus provides an ex cellent framework for assessing new discoveries in this field for some time to come.
Over the years, a large and growing literature on the economics of climate change has developed. Within this volume the contributors have included a wide range of journal essays that consider the impact of climate change on specific sectors; goods and services; the costs and benefits of greenhouse gas (GHG) mitigation; and policy design for mitigation, including both domestic instruments and issues related to international agreements.
This long-anticipated work is the final volume of the CTMMA series and completes the publication of all the cuneiform-inscribed tablets and inscriptions (excluding those on sculptures, reliefs, and seals) in the collection of The Metropolitan Museum of Art. Published are 183 texts that include 154 cuneiform tablets and tablet fragments, one inscribed clay bulla, fourteen clay cylinders, five clay prisms, and four stone inscriptions. Economic and Administrative texts are from Sippar, Babylon, Kish, Dilbat, Nippur, Drehem, Uruk, and other sites in Babylonia and ancient Iran. First millennium B.C. royal inscriptions date to the reigns of Ashurnasirpal, Sennacherib, Esarhaddon, Ashurbanipal, Nebuchadnezzar, and Nabonidus. The texts are organized in five parts: Part One contains Neo- and Late Babylonian economic and administrative tablets and fragments from the archives of the Ebabbar temple in Sippar. Part Two includes Neo- and Late Babylonian period economic and administrative tablets from Babylonia and other sites. Part Three includes Late Babylonian administrative and archival tablets from Babylon. Part Four contains royal and non-royal brick, stone, bulla, cylinder, and prism inscriptions from the second and first millennia B.C. A final section (Part Five) includes three proto-cuneiform archaic tablets and two Ur III administrative tablets. Professors Ira Spar (Professor of Ancient Studies at Ramapo College of New Jersey and Research Assyriologist at The Metropolitan Museum of Art) and Michael Jursa (University Professor of Assyriology, University of Vienna) were assisted by a team of distinguished scholars and conservators who provided valuable insights into the preparation of scholarly editions of the texts, seal impressions, and technical analysis published in this volume. Ira Spar hand copied and made facsimile drawings of the Museum’s texts with the assistance of Charles H. Wood. Jo Ann Wood-Brown and Charles H. Wood prepared drawings of seal impressions and divine symbols. This four-volume series of publications reaffirms the Museum’s ongoing commitment to promoting wider knowledge of ancient Near Eastern civilizations. Volume one documents 120 tablets, cones, and bricks from the third and second millennia B.C. Volume two publishes 106 religious, scientific, scholastic, and literary texts written in Akkadian and Sumerian that primarily date to the later part of the first millennium B.C. Volume three includes 164 private archival texts and fragments from the first millennium B.C. 442 pages, 174 plates, including drawings of 183 texts and photographs of selected tablets.
A unique presentation that unifies the field, this book brings together concepts and information about contaminant effects at all levels of the biological hierarchy. Beginning at the biomolecular level, this book builds progressively toward a discussion of effects to the global biosphere. Emphasizing ecological components and fundamental paradigms, the authors strike a balance between the presentation of details relevant at each level and the integration of phenomena and processes among levels. A milestone in the field, the book is suitable for graduate courses, as well as a reference for professionals in the field.
The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.
Biosensor technology has rapidly expanded into a wide variety of applications in the last few years. This book focuses on several aspects of neural behavior both in vitro and in vivo, and for the first time, the detection of populations of neurons is presented.
This third edition of Reconstructing Quaternary Environments has been completely revised and updated to provide a new account of the history and scale of environmental changes during the Quaternary. The evidence is extremely diverse ranging from landforms and sediments to fossil assemblages and geochemical data, and includes new data from terrestrial, marine and ice-core records. Dating methods are described and evaluated, while the principles and practices of Quaternary stratigraphy are also discussed. The volume concludes with a new chapter which considers some of the key questions about the nature, causes and consequences of global climatic and environmental change over a range of temporal scales. This synthesis builds on the methods and approaches described earlier in the book to show how a number of exciting ideas that have emerged over the last two decades are providing new insights into the operation of the global earth-ocean-atmosphere system, and are now central to many areas of contemporary Quaternary research. This comprehensive and dynamic textbook is richly illustrated throughout with full-colour figures and photographs. The book will be of interest to undergraduates, postgraduates and professionals in Earth Science, Environmental Science, Physical Geography, Geology, Botany, Zoology, Ecology, Archaeology and Anthropology
Psychology: The Science of Mind and Behaviour is here with a new, fully updated and revised third edition. Bringing new developments in the field and its renowned pedagogical design, the third edition offers an exciting and engaging introduction to the study of psychology.This book’s scientific approach, which brings together international research, practical application and the levels of analysis framework, encourages critical thinking about psychology and its impact on our daily lives. Key features: Fully updated research and data throughout the book as well as increased cross cultural referencesRestructured Chapter 3 on Genes, Environment and Behaviour, which now starts with a discussion of Darwinian theory before moving on to Mendelian geneticsCore subject updates such as DSM-5 for psychological disorders and imaging techniques on the brain are fully integratedRevised and updated Research Close Up boxesCurrent Issues and hot topics such as, the study of happiness and schizophrenia, intelligence testing, the influence of the media and conflict and terrorism are discussed to prompt debates and questions facing psychologists todayNew to this edition is Recommended Reading of both classic and contemporary studies at the end of chapters Connect™ Psychology: a digital teaching and learning environment that improves performance over a variety of critical outcomes; easy to use and proven effective. LearnSmart™: the most widely used and intelligent adaptive learning resource that is proven to strengthen memory recall, improve course retention and boost grades. SmartBook™: Fuelled by LearnSmart, SmartBook is the first and only adaptive reading experience available today.
Systems thinking tells us that human error, violations and technology failures result from poorly designed and managed work systems. To help us understand and prevent injuries and incidents, incident reporting systems must be capable of collecting data on contributory factors from across the overall work system, in addition to factors relating to the immediate context of the event (e.g. front-line workers, environment, and equipment). This book describes how to design a practical, usable incident reporting system based on this approach. The book contains all the information needed to effectively design and implement a new incident reporting system underpinned by systems thinking. It also provides guidance on how to evaluate and improve existing incident reporting systems so they are practical for users, collect good quality data, and reflect the principles of systems thinking. Features Highlights the key principles of systems thinking for designing incident reporting systems Outlines a process for developing and testing incident reporting systems Describes how to evaluate incident reporting systems to ensure they are practical, usable, and collect good quality data Provides detailed guidance on how to analyze incident data, and translate the findings into appropriate incident prevention strategies
In this book, Mu crafts a sociology of resilience through his multi-year research with Australian students. The content is not merely concerned with individual achievements in precarious conditions but also ponders over transformative, reflexive, and power-rejective everyday practices that make social change possible, probable, and even inevitable. Since Emmy Werner and her colleagues discovered the "self-righting" and "invincible" children on the Hawaiian island of Kauai who fared well despite exposure to significant household risks, positive psychology has markedly advanced the knowledge about child and youth resilience to adversities. Yet, many children and adolescents continue to slide through system cracks. This fact does not invalidate psychology of resilience; rather, it urges new frameworks to break the reproductive circle of inequality. Reframing the traditional psychological notion of resilience through recourse to Bourdieu’s relational and reflexive sociology, the book moves beyond individual adaptation to adverse conditions and takes a deep dive into sociological resilience to structural problems. It offers school professionals and educational researchers an epistemological tool to reapproach resilience and reappropriate Bourdieu for social change. Offering scholarship that will interest researchers in the areas of child and youth resilience, sociology of resilience, and sociology of education, the volume is written to engage with the intellectual work of both established scholars and emerging researchers within Australia and beyond. The empirical analyses also provide useful insights for educational professionals in schools and resilience researchers in universities.
Spectral Data for Steroids provides a comprehensive compilation of spectral data for 211 steroids. The compounds are arranged on the basis of their molecular structures:
This book provides an overview of, and practical guidance on, the range of human factors (HF) methods that can be used for the purposes of accident analysis and investigation in complex sociotechnical systems. Human Factors Methods and Accident Analysis begins with an overview of different accident causation models and an introduction to the concepts of accident analysis and investigation. It then presents a discussion focussing on the importance of, and difficulties associated with, collecting appropriate data for accident analysis purposes. Following this, a range of HF-based accident analysis methods are described, as well as step-by-step guidance on how to apply them. To demonstrate how the different methods are applied, and what the outputs are, the book presents a series of case study applications across a range of safety critical domains. It concludes with a chapter focussing on the data challenges faced when collecting, coding and analysing accident data, along with future directions in the area. Human Factors Methods and Accident Analysis is the first book to offer a practical guide for investigators, practitioners and researchers wishing to apply accident analysis methods. It is also unique in presenting a series of novel applications of accident analysis methods, including HF methods not previously used for these purposes (e.g. EAST, critical path analysis), as well as applications of methods in new domains.
Pediatric Neuro-Ophthalmology, 3rd edition provides the single authoritative resource on the pathophysiology, diagnostic evaluation, and treatment of neuro-ophthalmologic disorders in children. This book is encyclopedic in scope, incorporating extensive references for each condition, numerous diagrams and pictures, and a detailed analysis of the clinical disorders included in the differential diagnosis of each condition. The third edition builds upon this format to incorporate new discoveries about mechanisms of disease, new diagnostic modalities, advances in treatment in the field of pediatric neuro-ophthalmology, and updated neuroimaging figures.
Whether we live in cities, in the suburbs, or in the country, birds are ubiquitous features of daily life, so much so that we often take them for granted. But even the casual observer is aware that birds don’t fill our skies in the number they once did. That awareness has spawned conservation action that has led to notable successes, including the recovery of some of the nation’s most emblematic species, such as the Bald Eagle, Brown Pelican, Whooping Crane, and Peregrine Falcon. Despite this, a third of all American bird species are in trouble—in many cases, they’re in imminent danger of extinction. The most authoritative account ever published of the threats these species face, The American Bird Conservancy Guide to Bird Conservation will be the definitive book on the subject. The Guide presents for the first time anywhere a classification system and threat analysis for bird habitats in the United States, the most thorough and scientifically credible assessment of threats to birds published to date, as well as a new list of birds of conservation concern. Filled with beautiful color illustrations and original range maps, the Guide is a timely, important, and inspiring reference for birders and anyone else interested in conserving North America’s avian fauna. But this book is far more than another shout of crisis. The Guide also lays out a concrete and achievable plan of long-term action to safeguard our country’s rich bird life. Ultimately, it is an argument for hope. Whether you spend your early weekend mornings crouched in silence with binoculars in hand, hoping to check another species off your list, or you’ve never given much thought to bird conservation, you’ll appreciate the visual power and intellectual scope of these pages.
Over the last decade, the study of cycles as a model for the earth's changing climate has become a new science. Earth Systems Science is the basis for understanding all aspects of anthropogenic global change, such as chemically forced global climate change. The work is aimed at those students interested in the emerging scientific discipline.Earth Systems Science is an integrated discipline that has been rapidly developing over the last two decades. New information is included in this updated edition so that the text remains relevant. This volume contains five new chapters, but of special importance is the inclusion of an expanded set of student exercises.The two senior authors are leading scientists in their fields and have been awarded numerous prizes for their research efforts.* First edition was widely adopted* Authors are highly respected in their field* Global climate change, integral to the book, is now one of the most important issues in atmospheric sciences and oceanography
Principles of Stratigraphy reafferms the vital importance of stratigraphy to the earth sciences, and introduces the undergraduate to its key elements in a lively and interesting fashion. First recent text devoted to stratigraphic principles and applications. Contains details of the latest stratigraphic techniques. Includes numerous case studies and real-world examples. An Instructor manual CD-ROM for this title is available. Please contact our Higher Education team at HigherEducation@wiley.com for more information.
Mammals of Africa (MoA) is a series of six volumes which describes, in detail, every currently recognized species of African land mammal. This is the first time that such extensive coverage has ever been attempted, and the volumes incorporate the very latest information and detailed discussion of the morphology, distribution, biology and evolution (including reference to fossil and molecular data) of Africa's mammals. With 1,160 species and 16 orders, Africa has the greatest diversity and abundance of mammals in the world. The reasons for this and the mechanisms behind their evolution are given special attention in the series. Each volume follows the same format, with detailed profiles of every species and higher taxa. The series includes some 660 colour illustrations by Jonathan Kingdon and his many drawings highlight details of morphology and behaviour of the species concerned. Diagrams, schematic details and line drawings of skulls and jaws are by Jonathan Kingdon and Meredith Happold. Every species also includes a detailed distribution map. Extensive references alert readers to more detailed information. Volume I: Introductory Chapters and Afrotheria (352 pages) Volume II: Primates (560 pages) Volume III: Rodents, Hares and Rabbits (784 pages) Volume IV: Hedgehogs, Shrews and Bats (800 pages) Volume V: Carnivores, Pangolins, Equids and Rhinoceroses (560 pages) Volume VI: Pigs, Hippopotamuses, Chevrotain, Giraffes, Deer and Bovids (704 pages)
In an attempt to reverse declining rates of voter participation, governments around the world are turning to electronic voting to improve the efficiency of vote counts, and increase the accessibility and equity of the voting process for electors who may face additional barriers. The Covid-19 pandemic has intensified this trend. Voting Online focuses on Canada, where the technology has been widely embraced by municipal governments with one of the highest rates of use in the world. In the age of cyber elections, Canada is the only country where governments offer fully remote electronic elections and where traditional paper voting is eliminated for entire electorates. Municipalities are the laboratories of electoral modernization when it comes to digital voting reform. We know conspicuously little about the effects of these changes, particularly the elimination of paper ballots. Relying on surveys of voters, non-voters, and candidates in twenty Ontario cities, and a survey of administrators across the province of Ontario, Voting Online provides a holistic view of electronic elections unavailable anywhere else.
Sunderland is largely a product of the eighteenth and nineteenth centuries, when coalmining and shipbuilding fuelled rapid expansion and development. Once known as the 'largest shipbuilding town in the world', Sunderland's proud and distinctive identity is embodied in its historic buildings and in its changing urban form. The Architecture of Sunderland, 1700-1914 examines the city's architectural history during the highpoint of its growth and prosperity. Exploring the cityscape from the richest to the humblest buildings, it brings to life the economic, social and cultural forces that have shaped the city. The text is illustrated with fascinating archival images and photographs taken especially for this volume.
The third edition of this highly regarded book provides a concise and accessible introduction to the principles and elements of policy design in contemporary governance. It examines in detail the range of substantive and procedural policy instruments that together comprise the toolbox from which governments choose tools to resolve policy problems and the principles and practices that lead to their use. Guiding readers through the study of the many different kinds of instruments used by governments in carrying out their tasks, adapting to, and altering, their environments, this book: • Considers the principles and practices behind the selection and use of specific types of Instruments in contemporary government and arrangements of policy tools esp. procedural tools and policy portfolios. • Evaluates in detail the merits, demerits, and rationales for the use of specific organization, regulatory, financial and information-based tools and the trends visible in their use. • Examines key issues such as policy success and failure and the role of design in it; policy volatility and risk management through policy design; how behavioural research can contribute to better policy designs; and the 'micro' calibrations of policies and their importance in designs and outcomes. • Addresses the issues not only surrounding individual tools but also concerning the evolution and development of instrument mixes, their relationship to policy styles and the challenges involved in their (re)design as well as the distinction between design and "non-design'. Providing a comprehensive overview of this essential component of modern governance and featuring helpful definitions of key concepts and further reading, this book is essential reading for all students of public policy, administration, and management.
The best theatrical read of the year." – British Theatre Guide A book of selected theatre reviews from 1992 to 2020 from one of the foremost authorities on British theatre. Each chapter starts with a brief commentary on the developments of that era and the social, political and cultural context within which British theatre was being produced. Key obituaries and letters in response to reviews written are also included, providing a rich collection of curated archival material. Following on from his first collection, One Night Stands, Michael Billington's chronicle offers a rich, authoritative insight into British theatre over the last 3 decades from his unique professional perspective. It begins with Tony Kushner's UK premiere of Angels in America at the National Theatre in 1992 and culminates with Inua Ellams's celebrated adaptation of Chekhov's Three Sisters at the same venue almost 30 years later. En route, we're exposed to the fallibility of theatre criticism through his much-regretted original criticism of Sarah Kane's Blasted and its role in identifying major talents at the first opportunity. Having recently retired from his 48-year position as the Guardian newspaper's drama critic during which time he wrote around 10,000 theatre reviews, Michael Billiington was Britain's longest-serving theatre critic. Through his work, he was present at an eye-watering number of premieres during this time and witnessed first-hand the exciting developments in British theatre over the past 30 years and the substantial pressures it faced - never more so than today.
The “Hikayat Banjar,” a native court chronicle from Borneo, characterizes the irresistibility of natural resource wealth to outsiders as “the banana tree at the gate.” Michael R. Dove employs this phrase as a root metaphor to frame the history of resource relations between the indigenous peoples of Borneo and the world system. In analyzing production and trade in forest products, pepper, and especially natural rubber, Dove shows that the involvement of Borneo’s native peoples in commodity production for global markets is ancient and highly successful and that processes of globalization began millennia ago. Dove’s analysis replaces the image of the isolated tropical forest community that needs to be helped into the global system with the reality of communities that have been so successful and competitive that they have had to fight political elites to keep from being forced out.
The economic theories of the English economist and social scientist J.A. Hobson (1858-1940) were pioneering for their time. This book critically analyses his theories and shows that many of them have contemporary relevance. Hobson is best known by today's economists for his underconsumption theory, which was recognised by Keynes as an important forerunner of The General Theory. Hobson's underconsumption theory is modelled and compared with the economic growth theories of Harrod and Domar. Also included are accounts of Hobson's theories in the areas of welfare economics, income distribution and prices, money and credit, and international economics. The book also outlines Hobson's theory of imperialism, which was addressed to an audience far wider than that of economists, and gained him international fame.
Presents authorataive coverage of state-of-the-art techniques for diagnosing and managing tumors of the spine and spinal cord. Covers fundamentals of spinal cord anatomy and the pathology of spinal tumors to evaluation, diagnosis, and treatment techniques for specific spinal tumors.
This comprehensive introduction to the physics and chemistry of Earth's atmosphere explains the science behind some of the most critical and intensely debated environmental controversies of our day. In it, one of the world's leading experts on planetary environments presents the background necessary to assess the complex effects of human activity on our atmosphere and climate. Unique in its breadth and depth of coverage, The Atmospheric Environment includes a survey of Earth's climatic history to provide a context for assessing the changes underway today. It is written for--and will be of lasting value to--a varied audience, including not only students but also professional scientists and others seeking a sophisticated but readable introduction to the frontiers of contemporary research on biogeochemistry, depletion of stratospheric ozone, tropospheric air pollution, and climatology. The book covers both the chemistry and physics of the atmosphere with an account of relevant aspects of ocean science, treats atmospheric science and the climate as an integrated whole, and makes explicit the policy implications of what is known. Its critical account of steps taken by the international community to address the issue of climatic change highlights the challenge of dealing with a global issue for which the political and economic stakes are high, where uncertainties are common, and where there is an urgent need for clear thinking and informed policy. The book also sketches key gaps in our knowledge, outlining where we need to go to fully understand the impact of our actions on the climate. Thorough, timely, and authoritative, this is the book to consult for answers about some of the thorniest and most pressing environmental questions that we face.
This comprehensive text presents a critical discussion of the scopes and limitations of various organic synthetic methodologies that are available for performing asymmetric transformations. In addition to purely chemical methods, the book covers applications of new enzymes and other biological systems that are increasingly useful in asymmetric methodology.
Organic transformations are the heart of synthetic organic chemistry. The Compendium of Organic Synthetic Methods series facilitates the search for the most useful functional group transformations in organic chemistry. Compendium of Organic Synthetic Methods, Volume 9, provides quick access to proven protocols for the newest, most useful reactions and transformations. It contains both functional group transformations and bond-forming reactions, and focuses on the use of reagents readily available or easily prepared and handled in the laboratory. This valuable desktop resource contains over 1,200 examples of published reactions for the preparation of monofunctional compounds in a handy reference, as well as over 800 examples of difunctional compounds, and features over 30 more reviews than Volume 8. As in all the previous Compendium volumes, the classification schemes used allow for quick and easy reference and information retrieval. Chemical transformations are classified by the reacting functional group of the starting material and then by the functional group formed. Helpful indices are provided for both monofunctional and difunctional compounds as an efficient means of guidance to specific classes of transformations. Compendium of Organic Synthetic Methods, Volume 9, is an unparalleled source of information on the methods, reactions, and transformations in contemporary organic chemistry for the working chemist and student. Volume 9 in the series originated by I. T. Harrison and S. Harrison
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