The use of Italian culture in the Jacobean theatre was never an isolated gesture. In considering the ideological repercussions of references to Italy in prominent works by Shakespeare and his contemporaries, Michael J. Redmond argues that early modern intertextuality was a dynamic process of allusion, quotation, and revision. Beyond any individual narrative source, Redmond foregrounds the fundamental role of Italian textual precedents in the staging of domestic anxieties about state crisis, nationalism, and court intrigue. By focusing on the self-conscious, overt rehearsal of existing texts and genres, the book offers a new approach to the intertextual strategies of early modern English political drama. The pervasive circulation of Cinquecento political theorists like Machiavelli, Castiglione, and Guicciardini combined with recurrent English representations of Italy to ensure that the negotiation with previous writing formed an integral part of the dramatic agendas of period plays.
Winston Churchill was only 20 when he met the man whom he credited, more than any other, with shaping him as a statesman and an orator. As Churchill wrote: “I regard his as the biggest and most original mind I have ever met. When I was a young man, he instantly gained my confidence and I feel that I owe the best things in my life to him.” That man was Bourke Cockran, a charismatic Irish-born Democratic Congressman from New York City, acclaimed by his peers as the greatest orator in the Gilded Age of politics. Following the death of Winston’s father, Lord Randolph in 1895, Cockran who as a widower, became the lover of Churchill’s mother, the beautiful American-born heiress Jennie Jerome, who persuaded Cockran to take her son under his wing. Churchill, Cockran, Randolph, Politics, British, Prime Minister, New York, Democratic Congressman, Young Life, Mentor, American
This definitive, up-to-the-minute reference explores the range of metabolic, nutritional, immunologic, and psychological changes that can occur while treating local, regional, and distant cancer, and examines the influence of these factors on outcomes and recovery. Includes clearly written, concise summaries of oncological therapy emphasizing c
Perry’s The Chemotherapy Source Book, now in its fifth edition, provides information on the choice of chemotherapeutic agents, the use of combination chemotherapy, and the toxicity of individual drugs. Organized by site, this is the only book of its kind to focus strictly on the clinical practice of chemotherapy, and is meant to serve as a “one-stop shop” for information on choice of chemotherapeutic agents, treatment outlines, grading of side effects, and dose modification.
This text definitively breaks down each component of the Eco-Management and Audit Scheme regulation (EMAS) – even its appendices and EU guidance documents - providing a step-by-step analysis of the Scheme. In addition, the work offers case examples of three of Akzo Nobel manufacturing locations which have been registered to EMAS, providing real-world advice on how to meet the requirements of the Scheme.
The European Union (EU) Constitution was one of the most important developments in the history of the EU, aiming to make the EU more transparent, relevant and accountable to the citizens of its member states. Current anxieties over the pace and direction of EU integration place this comprehensive study at the forefront of the EU governance debate. O’Neill goes far beyond a simple account of the EU Constitution, focussing also on the response to the current crisis of confidence between the Union and its citizens and how those in power have responded to the challenge. Making a substantial contribution to literature on the EU, key discussion points include: The political crisis behind the Constitution The power politics at work in the negotiations How the Constitution affects EU policymaking The impact on the citizens of the EU This is essential reading for all those wishing to understand the background to one of the key areas within European Politics. Michael O’Neill is Jean Monnet Professor in EU Politics at Nottingham Trent University.
The Fifth Edition of Greenfield's Surgery has been thoroughly revised, updated, and refocused to conform to changes in surgical education and practice. Reflecting the increasingly clinical emphasis of residency programs, this edition features expanded coverage of clinical material and increased use of clinical algorithms. Key Points open each chapter, and icons in the text indicate where Key Points are fully discussed. Many of the black-and-white images from the previous edition have been replaced by full-color images. This edition has new chapters on quality assessment, surgical education, and surgical processes in the hospital. Coverage of surgical subspecialty areas is more sharply focused on topics that are encountered by general surgeons and included in the current general surgery curriculum and ABSITE exam. The vascular section has been further consolidated. A new editor, Diane M. Simeone, MD, PhD, has joined the editorial team. This edition is available either in one hardbound volume or in a four-volume softbound set. The lightweight four-volume option offers easy portability and quick access. Each volume is organized by organ system so you can find the facts you need within seconds. The companion website presents the fully searchable text, an instant-feedback test bank featuring over 800 questions and answers, and a comprehensive image bank. Unique to this new edition's website are 100 "Morbidity and Mortality" case discussions. Each case reviews a specific surgical complication, how the complication was addressed, and reviews the literature on approaches and outcomes.
Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease. Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy. The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.
Looks at the lives and politics of four of the key players in the independence and labour movements of the 19th century: Daniel O'Connell (1775-1847); Charles Stewart Parnell (1846-91); Michael Davitt (1846-1906); and James Bronterre O'Brien (1805-64). Volume 2 looks at the life of Charles Stewart Parnell.
This new volume in the Surgical Foundations series delivers need-to-know, current information in breast surgery in an exceptionally economical and user-friendly format. Coverage encompasses everything from anatomy and physiology, evaluation of breast symptoms...to discussions of breast cancer risk and management of breast cancer, equipping you to face any challenge with confidence. Whether reviewing key material in preparation for a procedure or studying for the boards, this is an invaluable resource in training and practice. Presents coverage that encompasses anatomy and physiology, evaluation of breast symptoms, breast cancer risk, and management of breast cancer to equip you to face any challenge with confidence. Addresses hot topics including gynecomastia, neoadjuvant therapy, management of ductal carcinoma in situ and Paget’s disease, risk assessment and genetic testing, breast MRI, partial breast irradiation, microarray analysis, and targeted therapies...providing you with a current perspective on this fast changing field. Begins each chapter with a bulleted list of key points, and presents crucial facts in boxes, to help facilitate review. Features abundant illustrations, photographs, and tables that clarify complex concepts. Follows a concise, logical, and consistent organization that makes the material easy to review.
Michael Wehmeyer, a leading scholar with over four decades of experience as a teacher, teacher educator, researcher, and advocate, provides a cogent but accessible account of the evolution of special education. Offering a compelling vision of where the field should be headed in the next decade, he notes how the digital revolution has made it possible for all learners to gain access to content and instruction. This text focuses on the need to consider how young people with (and without) disabilities learn and the importance of creating personalizable education as strengths-based approaches to disability move education away from diagnosis and remediation to schoolwide instruction for all students. This book is not written as a criticism of traditional special education models, but instead examines the big ideas for going beyond special education that can improve outcomes for learners with disabilities and prepare them for the 21st-century world. Book Features: Provides a framework for reconceptualizing how students with disabilities are educated. Content aligns with changing contexts and innovations in education, including personalizable education and self-determined learning. Identifies current, well-established practices that can facilitate efforts to address 21st-century learning needs for learners with disabilities. Written in a conversational voice for a broad audience to stimulate consideration of future directions for special education.
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences. Circadian Rhythms contains an extensive discussion of genetic and biochemical aspects of circadian rhythms. In this volume organisms such as neurospora, bacteria, drosophila, arabidopsis and mammals are covered. Included are methods in genetics, transcriptional and post-transcriptional regulation, tissue culture, and populations are discussed in detail.* One of the most highly respected publications in the field of biochemistry since 1955 * Frequently consulted, and praised by researchers and reviewers alike * Truly an essential publication for anyone in any field of the life sciences
Explore the many changes in hip and knee arthroplasty in recent years with completely new information on implants, bearing surfaces, surgical approaches, alternate approaches, risk reduction, and blood management. Expand your knowledge with the standard in adult hip and knee reconstruction, while you advance patient care with the best practices available.
A discussion of the diagnosis of breast cancer and the risks, benefits and limitations of treatment alternatives, particularly tamoxifen. This edition contains information on developments in the use of tamoxifen, especially in the results of the Breast Cancer Prevention Trial.
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