Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. A full Solutions Manual is also available online for qualified instructors, to support teaching. - Winner, 2018 Textbook Excellence Award (Texty) from the Textbook and Academic Authors Association - Fully revised and updated throughout, and organized into 19 chapters for a more cogent and versatile presentation of concepts - Includes reaction examples taken from literature research reported between 2010-2015 - Features new full-color art and new chapter content on process chemistry and green organic chemistry - Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Solutions Manual for qualified course instructors
How are new technologies changing the practice of law? With examples and explanations drawn from the UK, US, Canada, Australia and other common law countries, as well as from China and Europe, this book considers the opportunities and implications for lawyers as artificial intelligence systems become commonplace in legal service delivery. It examines what lawyers do in the practice of law and where AI will impact this work. It also explains the important continuing role of the lawyer in an AI world. This book is divided into three parts: Part A provides an accessible explanation of AI, including diagrams, and contrasts this with the role and work of lawyers. Part B focuses on six different aspects of legal work (litigation, transactional, dispute resolution, regulation and compliance, criminal law and legal advice and strategy) where AI is making a considerable impact and looks at how this is occurring. Part C discusses how lawyers and law firms can best utilise the promise of AI, while also acknowledging its limitations. It also discusses ethical and regulatory issues, including the lawyer's role in upholding the rule of law.
A fascinating look at a previously ignored piece of our nation's history, Black Diplomacy covers integration of the State Department after 1945 and the subsequent appointments of Black ambassadors to Third World and African nations. In seven illuminating chapters, Krenn covers the efforts to integrate the State Department; the setbacks during the Eisenhower years; and the gains achieved during the administrations of JFK and LBJ. Not content with simply using traditional sources (federal and other governmental agency records), he gained fresh insights from the papers of the NAACP, African American newspapers, and journals of the period. He also conducted original interviews with Edward Dudley (America's first black ambassador), Richard Fox, Horace Dawson, Ronald Palmer, and Terrence Todman (never before interviewed--ambassador to six nations beginning in 1952, and an assistant secretary of state). This unique look at the period will be of interest to anyone attempting to understand both the history of the civil rights movement in the U.S. and America's Cold War relations with underdeveloped nations during the quarter century after World War II.
On June 3, 1513, ships commanded by Juan Ponce de Leon were attacked by a group of Calusa Indians in one of the first hostile encounters recorded between Europeans and American Indians. Over the next four centuries, fundamental differences would cause these two disparate cultures to clash numerous times with untold loss of life and property. From the 1500s through 1901, this comprehensive reference book details individual armed conflicts between Native Americans and Europeans. Chronologically arranged entries include information such as origin of the European party, Indian tribe involved (if known), location of the skirmish and number of casualties. The establishments of various forts are also given within the chronology. An appendix provides a brief summary of related events after 1901.
In the wake of 9/11, the United States government rediscovered the value of culture in international relations, sending cultural ambassadors around the world to promote the American way of life. This is the most recent effort to use American culture as a means to convince others that the United States is a land of freedom, equality, opportunity, and scientific and cultural achievements to match its material wealth and military prowess. In The History of United States Cultural Diplomacy Michael Krenn charts the history of the cultural diplomacy efforts from Benjamin Franklin's service as commissioner to France in the 1770s through to the present day. He explores how these efforts were sometimes inspiring, often disastrous, and nearly always controversial attempts to tell the 'truth' about America. This is the first comprehensive study of America's efforts in the field of cultural diplomacy. It reveals a dynamic conflict between those who view U.S. culture as a means to establish meaningful dialogues with the rest of the world and those who consider American art, music, theater as additional propaganda weapons.
This text covers integration of the State Department after 1945 and the subsequent appointments of Black ambassadors to Third World and African nations. Other topics include: the setbacks during the Eisenhower years and the gains achieved during the Kennedy and Johnson administrations.
The Leader Within: Understanding and Empowering Teacher Leaders will assist schools in developing effective teacher leaders based on the Teacher Leader Model Standards. The goal of growing a culture of teacher leadership is to assist in creating a school culture committed to raising student achievement. This book is not intended to be solely used as a means of professional development, but to grow teacher leadership in schools and school districts. The center of effective teacher leadership is empowering teachers to be leaders in establishing a culture that is focused on student development and growth.
(From the Foreword) Graham-Paige Motors Corporation lives again in the pages of the The Graham Legacy: Graham-Paige to 1932. Michael E. Keller's factual account is based upon his thorough research, giving a clear picture of the formation and operations of this former Dearborn, Michigan, automaker. Keller addresses the myriad of Graham others' trucks, Paige, Graham-Paige and Graham automobile types and provides a full recounting of these vehicles' mechanical and styling details. In addition, the book incorporates the history of the three Graham brothers (Joseph, Robert and Ray) who rose from near anonymity to positions of prominence in such diverse fields as farming and glass manufacturing to the production of trucks and fine automobiles. This blending of historical, personal, business and technical aspects result in an informative and thoroughly interesting read.
This first study on Woodrow Wilson as the commander in chief during the Great War analyzes his management style before the war, his diplomacy and his battle with the Senate. It considers the war as representing the collapse of Western traditional virtues and examines Wilson's attempt to restore them. Emphasizing the American war effort on the domestic front, it also discusses Wilson's rise to power, his education, career, and work as governor as necessary steps in his formation. The authors deal honestly and critically with the racism that characterized this brilliant but limited career.
Compendium of Organic Synthetic Methods, Volume 11 continues the motivation of the series, which is to facilitate the search for quality, selected functional group transformations, organized by reacting functional group of starting material and functional group formed, with full references to each reaction.
Phayer explores the actions of the Catholic Church and the actions of individual Catholics during the crucial period from the emergence of Hitler until the Church's official rejection of antisemitism in 1965. 20 photos.
Sterile Drug Products: Formulation, Packaging, Manufacturing, and Quality teaches the basic principles of the development and manufacture of high quality sterile dosage forms. The author has 38 years of experience in the development and manufacture of sterile dosage forms including solutions, suspensions, ophthalmics and freeze dried products. This
The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.
An illustrated guide for working with PageMaker. Besides fully illustrated step-by-step instructions for specific techniques, text provides hints and guidelines for creating common desktop publishing projects, including ads, posters, annual reports, forms, stationery, and brochures.
Mystic Chords of Memory "Illustrated with hundreds of well-chosen anecdotes and minute observations . . . Kammen is a demon researcher who seems to have mined his nuggets from the entire corpus of American cultural history . . . insightful and sardonic." —Washington Post Book World In this ground-breaking, panoramic work of American cultural history, the Pulitzer Prize-winning author of A Machine That Would Go of Itself examines a central paradox of our national identity How did "the land of the future" acquire a past? And to what extent has our collective memory of that past—as embodied in our traditions—have been distorted, or even manufactured? Ranging from John Adams to Ronald Reagan, from the origins of Independence Day celebrations to the controversies surrounding the Vietnam War Memorial, from the Daughters of the American Revolution to immigrant associations, and filled with incisive analyses of such phenonema as Americana and its collectors, "historic" villages and Disneyland, Mystic Chords of Memory is a brilliant, immensely readable, and enormously important book. "Fascinating . . . a subtle and teeming narrative . . . masterly." —Time "This is a big, ambitious book, and Kammen pulls it off admirably. . . . [He] brings a prodigious mind and much scholarly rigor to his task . . . an importnat book—and a revealing look at how Americans look at themselves." —Milwaukee Journal
Stephan Klasen is considered one of the most distinguished scholars on gender economics in the 21st century. Over the past 25 years, he has tirelessly worked to understand the complex phenomena of gender inequality: From counting the number of missing women in the world and shedding light on why women go missing, to showing that leaving girls out of school not only deprives them, but also robs society of the opportunity to thrive on the talents of its entire population. From understanding why equal rights and rising incomes everywhere have not resulted in women participating more at work, to measuring gender inequality in its various dimensions. This volume, a collection of some of Stephan Klasens most important writings on the topic of gender inequality, honours his academic life and gives the reader an in-depth insight into both what we know and do not yet know about the economics of gender inequality.
A Doody's Core Title for 2023! The #1 Textbook in Pharmacotherapy providing optimal patient outcomes using evidence-based medication therapies—updated with the latest advances and guidelines For more than 30 years, DiPiro’s Pharmacotherapy has been the essential textbook for learning how to properly select, administer, and monitor drugs―everything needed to provide safe, effective drug therapy across all therapeutic categories. This new edition has been fully updated with the latest evidence-based information and recommendations. With content from 300 expert contributors, this valuable resource offers detailed descriptions of common and uncommon disease states, including treatment by pharmacologic and non-pharmacologic means. Each disease chapter opens with a Patient Care Process, helping readers understand the collaborative care model in which pharmacists work and communicate with other healthcare providers for effective coordinated care. Here's why DiPiro's Pharmacotherapy: A Pathophysiologic Approach is the perfect learning tool for students, pharmacists, and other healthcare providers: All chapters provide the most current, reliable, and relevant information available Key concepts are included at the beginning of each chapter Clinical Presentation boxes concisely outline disease signs and symptoms New: Beyond the Book feature points readers to multimedia resources to deepen their understanding of the material Diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches clearly distinguish treatment pathways New: Drug monitoring tables have been added Patient care process boxes help readers know how to communicate with other health care providers New: Additional FREE E-Chapters are available on AccessPharmacy New: Over 2000 Review Questions to help prepare students!
This comprehensive, authoritative text presents the scientific foundations and clinical practice of neural blockade in both regional anesthesia and the management of pain. The descriptions and illustrations of pain mechanisms are considered classic examples. The Fourth Edition has been refined for clarity and flows logically from principles and pharmacology, to techniques for each anatomic region, to applications. This edition has two new co-editors and several new chapters on topics including neurologic complications, neural blockade for surgery, treatment of pain in older people, and complications in pain medicine. A companion Website will offer the fully searchable text and an image bank.
Through the Global Lens uses a global perspective to analyze human affairs. This text looks at each of the six social sciences (sociology, anthropology, political science, economics, psychology, and geography), and uses case studies, feature film analyses, maps, and photos to highlight important historical events and concepts throughout.
Merriam Press World War 2 History Series. A History of the 316th Troop Carrier Group, 1942-1945. Complete history utilizing the author's personal recollections and those of his comrades along with extensive archival research. Encompasses Headquarters, 36th, 37th, 44th and 45th Squadrons, the Group was part of the 52nd Troop Carrier Wing, Ninth Air Force, participating in the airborne/glider operations in Sicily, Italy, Normandy, Holland and Germany. 91 photos, 30 maps, 13 appendices, 428 footnotes, bibliography, index.
Dynastic Politics and the British Reformations, 1558-1630 revisits what used to be regarded as an entirely 'mainstream' topic in the historiography of the later sixteenth and early seventeenth centuries - namely, the link between royal dynastic politics and the outcome of the process usually referred to as 'the Reformation'. As everyone knows, the principal mode of transacting so much of what constituted public political activity in the early modern period, and especially of securing something like political obedience if not exactly stability, was through the often distinctly un-modern management of the crown's dynastic rights, via the line of royal succession and in particular through matching into other royal and princely families. Dynastically, the states of Europe resembled a vast sexual chess board on which the trick was to preserve, advance, and then match (to advantage) one's own most powerful pieces. This process and practice were, obviously, not unique to the sixteenth and seventeenth centuries. But the changes in religion generated by the discontents of western Christendom in the Reformation period made dynastic politics ideologically fraught in a way which had not been the case previously, in that certain modes of religious thought were now taken to reflect on, critique, and hinder this mode of exercising monarchical authority, sometimes even to the extent of defining who had the right to be king or queen.
Now more than ever health care professionals play an increased role in the promotion of health to populations. Unique and innovative, Interprofessional Perspectives for Community Practice: Promoting Health, Well-being and Quality of Life weaves everyday care into prevention, community, and population health, creating a new and more expansive vision of health for all without compromising traditional practices. Authors and editors Drs. Pizzi and Amir discuss and illustrate a client-centered preventive and health, well-being and quality of life approach rooted in best practice principles from interprofessional literature and firsthand experience. The text illustrates how allied health professionals implement those principles in their everyday and traditional practices with an emphasis on exploring health and well-being issues. Interprofessional Perspectives for Community Practice provides detailed guidance in program development and implementation. What’s included in Interprofessional Perspectives for Community: Clinical anecdotes on successful community practices A focus on primary and secondary prevention Assessments, interventions, and community practice examples Descriptions of community-based practice settings such as adult day care, independent living programs, hospice, and home health care Health and wellness across the lifespan Bonus chapters available online as PDFs for readers The first text of its kind to weave interprofessionalism, community practice, and health, well-being, and quality of life, Interprofessional Perspectives for Community Practice: Promoting Health, Well-being and Quality of Life is for all health care workers and students who wish to transfer practice skills from the clinical setting to a population-based program development model.
The chapters in this international collection investigate a wide range of theorizations of rurality and literacy; literate practices and pedagogies; questions of place, space, and sustainability; and representations of rurality that challenge simplistic conceptions of standardized literacy and the real-and-imagined world beyond the metropolis.
A survey and reassessment of the role of the army chaplain in its first 150 years. Few military or ecclesiastical figures are as controversial as the military chaplain, routinely attacked by pacifist and anticlerical commentators and too readily dismissed by religious and military historians. This highly revisionist study represents a complete reappraisal of the role of the British army chaplain and of the Royal Army Chaplains' Department in the first century and a half of its existence. Challenging old caricatures and stereotypes and drawing on a wealth of new archival material, it surveys the political, denominational and organisational development of the R.A.Ch.D., analyses the changing role and experience of the British army chaplain across the nineteenth century and the two World Wars, and addresses the wider significance of British army chaplaincy for Britain's military, religious and cultural history over the period c.1800-1950. MICHAEL SNAPE is Senior Lecturer in ModernHistory at the University of Birmingham. The volume has a Foreword by Richard Holmes.
For 25 years, Lewis's Child and Adolescent Psychiatry has been the cornerstone of every child and adolescent psychiatrist’s library. Now, three colleagues of Dr. Lewis at the world-renowned Yale Child Study Center, have substantially updated and revised this foundational textbook for its long-awaited fifth edition, the first in ten years. Encyclopedic in scope, it continues to serve as a broad reference, deftly encompassing and integrating scientific principles, research methodologies, and everyday clinical care.
One day in late 1906, seventy-one-year-old Mark Twain attended a meeting on copyright law at the Library of Congress. The arrival of the famous author caused the usual stir—but then Twain took off his overcoat to reveal a "snow-white" tailored suit and scandalized the room. His shocking outfit appalled and delighted his contemporaries, but far more than that, as Pulitzer Prize finalist Michael Shelden shows in this wonderful new biography, Twain had brilliantly staged this act of showmanship to cement his image, and his personal legend, in the public's imagination. That afternoon in Washington, less than four years before his death, marked the beginning of a vibrant, tumultuous period in Twain's life that would shape much of the now-famous image by which he has come to be known—America's indomitable icon, the Man in White. Although Mark Twain has long been one of our most beloved literary figures—Time magazine has declared him "our original superstar"—his final years have been largely misunderstood. Despite family tragedies, Twain's last half- decade was among the most dynamic periods in the author's life. With the spirit and vigor of a man fifty years younger, he continued to stir up trouble, perfecting his skill for living large. Writing ceaselessly and always ready with one of his legendary quips, Twain would risk his fortune, become the willing victim of a lost-at-sea hoax, and pick fights with King Leopold of Belgium and Mary Baker Eddy. Drawing on a number of unpublished sources, including Twain's own journals, letters, and a revealing four-hundred-page personal account kept under wraps for decades (and still yet to be published), Mark Twain: Man in White brings the legendary author's twilight years vividly to life, offering surprising insights, including an intimate, tender look at his family life. Filled with first-rate scholarship, rare and never-published Twain photos, delightful anecdotes, and memorable quotes, including numerous recovered Twainisms, this definitive biography of Twain's last years provides a remarkable portrait of the man himself and of the unforgettable era in American letters that, in many ways, he helped to create.
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