Neurodevelopmental disabilities are a common problem in child health. This book takes a comprehensive approach to addressing these often challenging clinical diagnoses. In particular, it focuses on the two most common of childhood neurodevelopmental disabilities: global developmental delay and developmental language impairment. It seeks to put forward our present conceptualization of these entities as well as their proper evaluation and assessment and diagnosis from a variety of perspectives. It also provides details on our current understanding of the scientific basis of these disorders and their underlying causes. Issues related to medical management, rehabilitation, and eventual outcomes are also addressed in a detailed way. The book has wide appeal to those in paediatrics, developmental paediatrics, child neurology, and paediatric rehabilitation. Its geographic appeal includes both developed and developing nations as some chapters are devoted to the particular issues faced in underdeveloped countries. The book’s focus on both clinical and scientific aspects is invaluable in this field. It also provides extensive information in a single source relating to often-overlooked areas such as medical management, rehabilitation, public policy, and ethics.
Areas addressed in this excellent text include the overall response of the endothelium to hemodynamic forces, and molecular biology with gene regulation taking a central role.
Get the essential tools you need to make an accurate diagnosis with Vascular and Interventional Radiology: The Requisites! This bestselling volume delivers the conceptual, factual, and interpretive information you need for effective clinical practice in vascular and interventional radiology, as well certification and recertification review. Master core knowledge the easy and affordable way with clear, concise text enhanced by at-a-glance illustrations, boxes, and tables – all completely rewritten to bring you up to date with today's state of the art in vascular and interventional radiology. - Understand the basics with a comprehensive yet manageable review of the principles and practice of vascular and interventional radiology. Whether you're a resident preparing for exams or a practitioner needing a quick-consult source of information, Vascular and Interventional Radiology is your guide to the field. - Master the latest techniques for liver-directed cancer interventions; arterial and venous interventions including stroke therapy; thoracic duct embolization; peripheral arterial interventions; venous interventions for thrombosis and reflux; percutaneous ablation procedures; and much more. - Prepare for the written board exam and for clinical practice with critical information on interventional techniques and procedures. - Clearly visualize the findings you're likely to see in practice and on exams with vibrant full-color images and new vascular chapter images. - Access the complete, fully searchable text and downloadable images online with Expert Consult.
Research on vitamin C and its effects on cancer is growing in popularity around the world as positive research continues to accumulate building a stronger case for its effectiveness. This concise SpringerBrief on Vitamin C and Cancer presents the latest findings on how vitamin C induces apoptosis. A high concentration of vitamin C allows for ascorbate to generate hydrogen peroxide in tissue that can selectively kill cancer cells. Research has confirmed that high-dose vitamin C is cytotoxic to a wide variety of cancer cell lines, and that it also boosts the anti-cancer activity of several common chemotherapy drugs. Vitamin C also does more than just kill cancer cells. It boosts immunity by stimulating collagen formation to help the body wall off the tumor. It inhibits hyaluronidase, an enzyme that tumors use to metastasize and invade other organs throughout the body. This concise and up-to-date Brief is geared towards cancer researchers and scientists, as well as physicians interested in the basic science and the translational potential of vitamin C in cancer therapeutics.
Plant Systematics, Third Edition, has made substantial contributions to plant systematics courses at the upper-undergraduate and first year graduate level, with the first edition winning The New York Botanical Garden's Henry Allan Gleason Award for outstanding recent publication in plant taxonomy, plant ecology or plant geography. This third edition continues to provide the basis for teaching an introduction to the morphology, evolution and classification of land plants. A foundation of the approach, methods, research goals, evidence and terminology of plant systematics are presented, along with the most recent knowledge of evolutionary relationships of plants and practical information vital to the field. In this new edition, the author includes greatly expanded treatments on families of flowering plants, as well as tropical trees (all with full-color plates), and an updated explanation of maximum likelihood and Bayesian inference algorithms. Chapters on morphology and plant nomenclature have also been enhanced with new material. - Covers research developments in plant molecular biology - Features clear, detailed cladograms, drawings and photos - Includes major revisions to chapters on phylogenetic systematics and plant morphology
This Synthesis Lecture focuses on techniques for efficient data orchestration within DNN accelerators. The End of Moore's Law, coupled with the increasing growth in deep learning and other AI applications has led to the emergence of custom Deep Neural Network (DNN) accelerators for energy-efficient inference on edge devices. Modern DNNs have millions of hyper parameters and involve billions of computations; this necessitates extensive data movement from memory to on-chip processing engines. It is well known that the cost of data movement today surpasses the cost of the actual computation; therefore, DNN accelerators require careful orchestration of data across on-chip compute, network, and memory elements to minimize the number of accesses to external DRAM. The book covers DNN dataflows, data reuse, buffer hierarchies, networks-on-chip, and automated design-space exploration. It concludes with data orchestration challenges with compressed and sparse DNNs and future trends. The target audience is students, engineers, and researchers interested in designing high-performance and low-energy accelerators for DNN inference.
Traditional research about Financial Stability and Sustainable Growth typically omits Earnings Management (as a broad class of misconduct), Complex Systems Theory, Mechanism Design Theory, Public Health, psychology issues, and the externalities and psychological effects of Fintech. Inequality, Environmental Pollution, Earnings Management opportunities, the varieties of complex Financial Instruments, Fintech, Regulatory Fragmentation, Regulatory Capture and real-financial sector-linkages are growing around the world, and these factors can have symbiotic relationships. Within Complex System theory framework, this book analyzes these foregoing issues, and introduces new behaviour theories, Enforcement Dichotomies, and critiques of models, regulations and theories in several dimensions. The issues analyzed can affect markets, and evolutions of systems, decision-making, "nternal Markets and risk-perception within government regulators, operating companies and investment entities, and thus they have Public Policy implications. The legal analysis uses applicable US case-law and statutes (which have been copied by many countries, and are similar to those of many common-law countries). Using Qualitative Reasoning, Capital Dynamics Theory (a new approach introduced in this book), Critical Theory and elements of Mechanism Design Theory, the book aims to enhance cross-disciplinary analysis of the above-mentioned issues; and to help researchers build better systems/Artificial-Intelligence/mathematical models in Financial Stability, Portfolio Management, Policy-Analysis, Asset Pricing, Contract Theory, Enforcement Theory and Fraud Detection. The primary audience for this book consists of university Professors, PHD students and PHD degree-holders (in industries, government agencies, financial services companies and research institutes). The book can be used as a primary or supplementary textbook for graduate courses in Regulation; Capital Markets; Law & Economics, International Political Economy and or Mechanism Design (Applied Math, Operations Research, Computer Science or Finance).
Magnetic Resonance Neuroimaging is a comprehensive volume that focuses on the newest fields of MRI from functional and metabolic mapping to the latest applications of neuro-interventional techniques. Each chapter offers critical discussions regarding available methods and the most recent advances in neuroimaging, including such topics as the use of diffusion and perfusion MRI in the early detection of stroke, the revolutionary advent of high-speed MRI for non-invasively mapping cortical responses to task activation paradigms, and the principles and applications of contrast agents. The chapters also discuss how these new advances are applied to problems in patients ranging in age from the newborn to the elderly, as well as disease states ranging from metabolic encephalopathy to cardiovascular disorders and stroke. Magnetic Resonance Neuroimaging will be a valuable text/reference for residents, research fellows, and clinicians in radiology, neuroradiology, and magnetic resonance imaging.
Few people know what wandering spurs are; fewer still know how to get rid of them. This book, which is written by those who raised awareness of wandering spurs, explained how they arise, and invented ways to get rid of them, contains valuable insights, analytical techniques and examples that will enable the reader to become an expert in the area. The book is aimed at circuit design professionals who need to ensure that their designs are not compromised by wandering spurs. In addition to insights, theory, and analysis, it contains practical circuit solutions, the performance of which are characterized experimentally. This book explains—using simulation, analysis, and experimental measurements—what wandering spurs are, how they arise, how to characterize them and, most importantly, how to get rid of them. The authors present not only theoretical analysis and simulation strategies, but also provide an overview of spectral analysis techniques for studying the phenomenon and convincing experimental results from both commercially available and custom-designed monolithic synthesizers. Explains what wandering spurs are and how they differ qualitatively from the well-known fixed spurs that plague fractional-N frequency synthesizers; Provides analytical and simulation methods to study wandering spurs and original analysis of the cause of this recently reported spectral phenomenon; Presents and analyses theoretical designs based on a conventional MASH 1-1-1 to mitigate wandering spurs; Describes measured performance for the discussed designs, confirming their effectiveness in mitigating wandering spurs.
Techniques in Hip Arthroscopy and Joint Preservation Surgery is a stunning visual guide to the latest developments in the field. Drs. Jon K. Sekiya, Marc Safran, and Anil S. Ranawat, and Michael Leunig provide a step-by-step, balanced approach—with contributions from an array of North American and international surgeons—to pre-operative planning, surgical technique, technical pearls, management of complications, and post-operative rehabilitation. Surgical videos online demonstrate techniques such as surgical hip dislocation for femoracetabular impingement and arthroscopic femoral osteoplasty so you can provide your patients with the best possible outcomes. - Access the fully searchable text online at www.expertconsult.com, along with a video library of surgical procedures. - Grasp the visual nuances of each technique through full-color surgical illustrations and intraoperative photographs. - Watch expert surgeons perform cutting edge procedures—such as complex therapeutic hip arthroscopy using a femoral distractor, arhroscopic synovectomy and treatment of synovial disorders, surgical hip dislocation for femoracetabular important, and arthroscopic femoral osteoplasty—online at www.expertconsult.com - Find information quickly and easily thanks to the consistent chapter format that includes technical pearls.
This book presents a detailed technical overview of short- and long-term materials and design challenges to zinc/bromine flow battery advancement, the need for energy storage in the electrical grid and how these may be met with the Zn/Br system. Practical interdisciplinary pathways forward are identified via cross-comparison and comprehensive review of significant findings from more than 300 published works, with clear in-depth explanations spanning initial RFB development to state-of-the-art research in related systems. Promising strategies described include the use of modern electrochemical techniques to study and optimize physical processes occurring within the system during operation, improving zinc electroplating quality during the charge phase through the strategic use of organic additives, as well as identifying suitable catalysts to optimize the bromine/bromide redox couple. The primary focus is on research and development of novel materials in the areas of electrolyte formulation and multifunctional “smart” electrode surfaces to achieve a higher degree of control over processes at the electrode–electrolyte interface. The strategies suggested in this book are also highly adaptable for use in other similar flow battery systems, while the unique cross-comparative approach makes it a useful reference and source of new ideas for both new and established researchers in the field of energy storage and battery technology.
The European Social Survey (the ESS) is an academically-driven social survey designed to chart and explain the interaction between Europe’s changing institutions and the attitudes, beliefs and behaviour patterns of its diverse populations. Established in 2001, and currently preparing for its seventh round, this biennial cross-sectional survey covers more than thirty nations and employs the most rigorous methodologies. This volume provides an analysis of the Irish data over six rounds of the European Social Survey, focusing on the internal changes over time in Ireland and situating these changes in a broader European context. The book’s core chapter deal with the primary themes of the European Social Survey: Institutional Trust, Democracy and Legitimacy; Political Engagement and Socio-Political Values; Moral and Social Values; Social Capital and Social Exclusion; and National, Ethnic, and Religious Identity. A separate chapter focuses on the survey’s rotating modules, which change from survey to survey. These topics include Citizenship, Involvement and Democracy; Immigration; Well-Being; Health; Economic Morality in Europe and Welfare Attitudes; and Trust in Criminal Justice. Each chapter provides a list of background literature to the topic in Ireland, an analysis of the data that will be both accessible for the general reader, but offering something deeper to the expert, and a clear comparison of how the Irish data fit in with the rest of Europe. This book charts a changing Ireland over a highly significant period of its history. Given the significance of the ESS as the most rigorous social science survey in Europe and the scope of its questionnaires, this volume is highly pertinent both in terms of how it maps political, social, demographic and attitudinal changes in Ireland, and in the way it places those changes within a European context.
At a time when the numbers of emerging infections and antibiotic-resistant bacteria are rising sharply, the supply of new antibiotic drugs has been steadily decreasing. In addition, many health providers have failed to consider that our bodies are cloaked in a blanket of bacteria so pervasive that the bacterial cells outnumber our “human” cells by a factor of ten. In short, we are living in a microbe’s world and cannot ignore the very real potential for untreatable serious infections. In this timely book, Dr. Michael Schmidt proposes we focus on strengthening ourselves by thinking of our bodies as a “human-microbe hybrid.” This requires taking action to raise our defenses, while preserving the integrity of the microbial elements that live on and within us. Drawing on the latest research from several scientific fields, Schmidt presents a strategy of medicine that can be used to build and balance our system of immune defense and repair. He offers a set of general recommendations that can easily be used to tailor programs to individuals seeking to support health maintenance, prevent illness, fight active acute or chronic infections, and foster faster recovery from infections.
Since its first edition over 60 years ago, Rockwood and Green’s Fractures in Adults has been the go-to reference for treating a wide range of fractures in adult patients. The landmark, two-volume tenth edition continues this tradition with two new international editors, a refreshed mix of contributors, and revised content throughout, bringing you fully up to date with today’s techniques and technologies for treating fractures in orthopaedics. Drs. Paul Tornetta III, William M. Ricci, Robert F. Ostrum, Michael D. McKee, Benjamin J. Ollivere, and Victor A. de Ridder lead a team of experts who ensure that the most up-to-date information is presented in a comprehensive yet easy to digest manner.
Biopolymers and biodegradable plastics are finding new applications in various sectors, from packaging, to medical, automotive and many more. As synthetic plastics are increasingly replaced by their bioplastic equivalents, engineers are facing new challenges including processing, costs, environmental sustainability and – ultimately – developing successful products. Biopolymers: Processing and Products, the second book of a trilogy dedicated to biopolymers, gives a detailed insight into all aspects of processing, seamlessly linking the science of biopolymers to the latest trends in the development of new products. Processes covered in the book include blending, compounding, treatment, and shaping, as well as the formation of biocomposites. Biopolymer coatings and adhesives are also investigated. This book unique in its coverage contains information retrieved mainly from patents, which form the bulk of the book. The coverage of processing will help engineers and designers to improve output and efficiency of every stage of the product development process, and will form an indispensable tool in selecting the right biopolymer and processing technique for any given application, covering medical, automotive, food packaging and more. It will assist also engineers, material scientists and researchers to improve existing biopolymer processes and deliver better products at lower cost. - Multi-disciplinary approach and critical presentation of all available processing techniques and new products of biopolymers - Contains information not to be found in any other book - Self-contained chapters
In this handbook, the leading experts in the field presents important and fundamental aspects of the organic and organometallic chemistry of fullerenes. Naturally they also cover the applications in material and medicinal science for these fascinating molecules. Completely self-contained, the book is logically arranged such that information is easy to retrieve, and the style lends itself to effortless reading and to learning more about the chemical properties of this family of molecules. A definitive "must" for everyone working in this ever-expanding sphere.
One important robotics problem is “How can one program a robot to perform a task”? Classical robotics solves this problem by manually engineering modules for state estimation, planning, and control. In contrast, robot learning solely relies on black-box models and data. This book shows that these two approaches of classical engineering and black-box machine learning are not mutually exclusive. To solve tasks with robots, one can transfer insights from classical robotics to deep networks and obtain better learning algorithms for robotics and control. To highlight that incorporating existing knowledge as inductive biases in machine learning algorithms improves performance, this book covers different approaches for learning dynamics models and learning robust control policies. The presented algorithms leverage the knowledge of Newtonian Mechanics, Lagrangian Mechanics as well as the Hamilton-Jacobi-Isaacs differential equation as inductive bias and are evaluated on physical robots.
50th Anniversary Edition of the groundbreaking case-based pharmacotherapy text, now a convenient two-volume set. Celebrating 50 years of excellence, Applied Therapeutics, 12th Edition, features contributions from more than 200 experienced clinicians. This acclaimed case-based approach promotes mastery and application of the fundamentals of drug therapeutics, guiding users from General Principles to specific disease coverage with accompanying problem-solving techniques that help users devise effective evidence-based drug treatment plans. Now in full color, the 12th Edition has been thoroughly updated throughout to reflect the ever-changing spectrum of drug knowledge and therapeutic approaches. New chapters ensure contemporary relevance and up-to-date IPE case studies train users to think like clinicians and confidently prepare for practice.
by E.K. ZSIGMOND, M.D. Department of Anesthesiology University of Illinois Chicago U.S.A. It is, indeed, a distinct honor and privilege to be invited by the authors to write a preface to this monumental monograph, Regional Opioid Analgesia. Regional Opioid Analgesia is a colossal undertaking by Drs. De Castro, Meynadier and Zenz shortly after the introduction of this revolutionary approach to pain relief which opened a new epoch in analgesiology. This is, indeed, the first authentic and comprehensive textbook encompassing the current knowl edge on this novel approach to pain relief. We are indebted to the authors for introducing the new opioids to regional analgesia with the scientists, who de veloped the potent short and ultrashort acting opioids with high therapeutic indices, which many researchers dreamt about but never before materialized. The side effect liabilities of these new opioids are minute as compared to morphine and meperidine. Regional Opioid Analgesia could not have been more authentically written than by Drs. De Castro,Zenz and Meynadier,who have conducted daily clinical investigations on all known opioids for regional analgesia as well as for neurolept analgesia. Therein lies the great value of this monograph: it is the most authentic work on this topic.
In Gatbered and Sent, Bernard Lee and Michael Cowan propose a mode of doing theology within small Christian communities that is marked by conversation and active participation by all. It is a practical theology where people reflect on their whole lives, personal and social, in the light of Christian faith, make commitments to action in light of that reflection, and hold one another accountable for those commitments."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Nutrients in Cancer Prevention and Treatment contains articles that were presented by leading researchers and physicians in the field of nutritional oncology. Most of the previous conference proceedings on Nutrition and Cancer have dealt primarily with the issue of the role of nutrients in cancer prevention. This is logical because enormous quantities of laboratory and epi demiologic data have been published on the topic. Nutrients in Cancer Prevention and Treatment also contains several studies on the role of diet and vitamins in cancer treat ment. There are very few books that have reviewed laboratory and clinical studies and the role of vitamins in cancer treatment. There are preliminary data suggesting that daily supplementa tion with high doses of certain vitamins in combination with conventional therapeutic agents may enhance their growth inhibitory effects on tumor cells, and may protect normal tissues against some of their toxic effects. This book is unique in the sense that several articles have discussed the mechanisms of action of individual vitamins on cellular and molecular parameters. It is very exciting to note that some of the vitamins inhibit protein kinase C activity, increase the production of certain growth factors, and modulate the expression of a number of oncogenes. These studies, at least in part, offer rationales for the cancer protective effects of vitamins.
Chromic or colour related phenomena are produced in response to a chemical or physical stimulus. This new edition will update the information on all those areas where chemicals or materials interact with light to produce colour, a colour change, or luminescence especially in the imaging, analysis, lighting and display areas. The book has been restructured to show greater emphasis on applications where 'coloured' compounds are used to transfer energy or manipulate light in some way therefore reducing the details on classical dyes and pigments. In the past eight years, since the previous edition, there has been a remarkable increase in the number of papers and reviews being produced reflecting the growth of interest in this area. This ongoing research interest is matched by a large number of new technological applications gaining commercial value covering e.g. biomedical areas, energy, data storage, physical colour, bio-inspired materials and photonics. This book appeals to industrial chemists, professionals, postgraduates and as high level recommended reading for colour technology courses.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
This new edition is revised throughout and includes new and expanded information on natural resource damage assessment, the latest emerging contaminants and issues, and adds new international coverage, including case studies and rules and regulations. The text details key environmental contaminants, explores their fates in the biosphere, and discusses bioaccumulation and the effects of contaminants at increasing levels of ecological organization. Vignettes written by experts illustrate key themes or highlight especially pertinent examples. This edition offers an instructors' solution manual, PowerPoint slides, and supplemental images. Features: Adds all new discussions of natural resource damage assessment concepts and approaches Includes new vignettes written by leading guest authors Draws on materials from 2,500 cited sources, including 400+ new to this edition Adds numerous new entries to a useful glossary of 800+ terms Includes a new appendix discussing Brazilian environmental laws and regulations added to existing appendices outlining U.S., E.U., Chinese, Australian, and Indian environmental laws Fundamentals of Ecotoxicology: The Science of Pollution, Fifth Edition contains a broad overview of ecotoxicology and provides a basic understanding of the field. Designed as a textbook for use in introductory graduate or upper-level undergraduate courses in ecotoxicology, applied ecology, environmental pollution, and environmental science, it can also be used as a general reference for practicing environmental toxicologists.
Clathrin-mediated endocytosis (CME) is a ubiquitous internalization process in eukaryotic cells. It consists of the formation of an approximately 50-nm diameter vesicle out of a flat membrane. Genetics, biochemistry, and microscopy experiments performed in the last four decades have been instrumental to discover and characterize major endocytic proteins in yeast and mammals. However, due to the highly dynamic nature of the endocytic assembly and its small size, many questions remain unresolved: how are endocytic proteins organized spatially and dynamically? How are forces produced and how are their directions controlled? How do the biochemical activities of endocytic proteins and the membrane shape and mechanics regulate each other? These questions are virtually impossible to visualize or measure directly with conventional approaches but thanks to new quantitative biology methods, it is now possible to infer the mechanisms of endocytosis in exquisite detail. This book introduces quantitative microscopy and mathematical modeling approaches that have been used to count the copy number of endocytic proteins, infer their localization with nanometer precision, and infer molecular and physical mechanisms that are involved in the robust formation of endocytic vesicles.
Clinical Anesthesia, Seventh Edition covers the full spectrum of clinical options, providing insightful coverage of pharmacology, physiology, co-existing diseases, and surgical procedures. This classic book is unmatched for its clarity and depth of coverage. *This version does not support the video and update content that is included with the print edition. Key Features: • Formatted to comply with Kindle specifications for easy reading • Comprehensive and heavily illustrated • Full color throughout • Key Points begin each chapter and are labeled throughout the chapter where they are discussed at length • Key References are highlighted • Written and edited by acknowledged leaders in the field • New chapter on Anesthesia for Laparoscopic and Robotic Surgery Whether you’re brushing up on the basics, or preparing for a complicated case, the digital version will let you take the content wherever you go.
This book covers the full range of current applications of Doppler sonography in infancy and childhood, describing the variety of potential findings with the aid of a wealth of images. After an introductory chapter on the physical and technical basis of Doppler sonography, applications of cerebral Doppler sonography in infancy and of transcranial Doppler sonography in childhood are addressed, with numerous examples of imaging appearances. The major part of the book is devoted to Doppler sonography of the brain, face and neck and of the abdomen, covering normal abdominal vessels, liver, spleen, pancreas, and mesenteric and renal circulation. Imaging of the ovaries and testes is also presented, encompassing the differential diagnosis of acute scrotum and other space-occupying lesions of the testis. The book closes by considering Doppler sonography of soft tissue and vascular malformations, and the influence of congenital heart malformations on flow parameters in peripheral arteries. Doppler Sonography in Infancy and Childhood will be an invaluable reference for pediatricians, neonatologists, pediatric sonographers, and pediatric and general radiologists.
This book provides in-depth information about common clinical laboratory assays that are used to evaluate domestic mammals, including what assays measure, sample or assay conditions that affect results, and what results indicate about the physiologic or pathologic state of a patient. Whenever possible, diseases and conditions are grouped by common mechanisms or processes to promote a conceptual understanding of laboratory data that can be generally applied across many species. New to the second edition are additional disorders, diagnostic tests, illustrations, images, references, and pathophysiologic explanations. This text has proven valuable to students and veterinarians wanting a fundamental understanding of veterinary clinical pathology.
The revised 2nd edition of this practical book provides an expanded treatment and comparison of techniques used in advanced optical measurements, guiding its reader from fundamental radiometric and photometric concepts to the state-of-the-art in highly sensitive measurements of optical losses and in spectroscopic detection using coherent laser light and spontaneous radiation. The book describes and compares a broad array of high-sensitivity methods and techniques – from interferometric and/or calorimetric, acousto-optic and resonator or polarization to wavelength- and frequency-modulation, phase-shift and decay time studies, and direct-loss measurements for free-space, fiber- or waveguide-based systems and devices. Updated throughout, the new edition describes novel trends in spectral interferometry, frequency-comb and laser-excitation spectroscopy, reflected in the developments of Raman, Brillouin and FTIR (Fourier Transform Infra-Red) techniques for biomedical research, biotech sensing and detection. It also covers broad practical implementations of time- and frequency-domain terahertz spectroscopy measurements. This book reviews the physical concepts of radiation transfer, providing a quantitative foundation for the means of measurements of optical losses, which affect propagation and distribution of light waves in various media and in diverse optical systems and components. It focuses on the application of optical methods and procedures for the evaluation of transparent, reflecting, scattering, absorbing, and aggregated objects, and for determining the power and energy parameters of radiation and color properties of light. This updated new edition will serve as an up-to-date reference source and practical guide for those using photometric and radiometric techniques.
Bayesian inference has become a standard method of analysis in many fields of science. Students and researchers in experimental psychology and cognitive science, however, have failed to take full advantage of the new and exciting possibilities that the Bayesian approach affords. Ideal for teaching and self study, this book demonstrates how to do Bayesian modeling. Short, to-the-point chapters offer examples, exercises, and computer code (using WinBUGS or JAGS, and supported by Matlab and R), with additional support available online. No advance knowledge of statistics is required and, from the very start, readers are encouraged to apply and adjust Bayesian analyses by themselves. The book contains a series of chapters on parameter estimation and model selection, followed by detailed case studies from cognitive science. After working through this book, readers should be able to build their own Bayesian models, apply the models to their own data, and draw their own conclusions.
Bands, bonds, and affections -- Secession all the way down : libertarians opt out -- "A slave republic" : secession and southern slavery -- White devils and Black separatists -- "Dykes first" : lesbian separatism in America -- Exodus as secession : achieving God's terrestrial kingdom.
Safe Water in Healthcare: A Practical and Clinical Guide enables users from different disciplines to understand all types of waterborne hazards that can pose a risk to those who might be exposed, the events which cause them to be present, what may precipitate an increase in their levels that may cause harm, and how they can be avoided or managed to reduce risk. The handbook highlights microorganisms that can cause infections, modes of transmission, the infections they cause, and risks. The book's authors draw from their extensive practical experience assisting with day-to-day problems that range from minor issues to outbreaks. The book includes case studies on the growth of biofilms and where they cause problems in water systems as well as providing practical answers to a majority of issues that arise in healthcare water and drainage systems. This is an accessible handbook that fills the gaps for those without technical knowledge for a complex but important area of infection control. It provides practical guidance for professionals who are required to design, manage and maintain water systems and help them manage associated infection outbreaks. - Discusses waterborne pathogens, their detection, identification and surveillance and describes the extent and range of recognized and emerging waterborne microorganisms as well as the diseases that occur and consequences to patients and staff - Covers hazards that can cause harm within water systems and associated equipment, the circumstances or factors that increase the risks, and the multiple modes of transmission of waterborne pathogens - Explains the importance of good design, including the type of design, management, hardware and software that can help manage and control the presence of waterborne pathogens. - Highlights who needs to be involved at each stage to ensure that patients are kept safe from waterborne pathogens, taking into account current legislation and best practices guidance
AIDS treatments continues to evolve. Now, so does the definitive reference on this complex and challenging subject! "AIDS Therapy, 3rd Edition" not only brings you comprehensive guidance on the latest treatments for HIV/AIDS and the full range of related disorders and syndromes, but also comes with access to updates online—so you can always tap into the most current therapy guidelines. Written by a "who's who" of leading global experts, the new edition of this classic reference is a must for any clinician who manages patients with HIV/AIDS. The most comprehensive coverage available on AIDS treatment equips you to meet any clinical challenge. Contributions from a large cast of noted international authorities put global "best practices" at your fingertips. Advice from some of the most respected experts in the field helps you manage your patients confidently. Available with a companion website allowing you to access the latest treatment guidelines year after year.
The 20 chapters in this book have been selected from the contents of the Abdominal Imaging section in Grainger & Allison's Diagnostic Radiology 6e. These chapters provide a succinct up-to-date overview of current imaging techniques and their clinical applications in daily practice and it is hoped that with this concise format the user will quickly grasp the fundamentals they need to know. Throughout these chapters, the relative merits of different imaging investigations are described, variations are discussed and recent imaging advances are detailed.
Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You’ll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors—such as heavy metals and pesticides—and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. Provides a complete listing of neurotoxic agents—from manufactured to environmental—so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson’s Disease, motor neuron disease, as well as other issues that are still in question.
This authoritative book introduces and summarizes the latest models and skills required to design and fabricate nanomechanical resonators with a focus on nanomechanical sensing. It also establishes the theoretical foundation for courses on micro and nanomechanics. This book takes an applied approach to nanomechanics, providing a complete set of mechanical models, including strings and membrane resonators. Also discussed are quality factors, noise issues, transduction techniques, nanomechanical sensing, fabrication techniques, and applications for all common nanomechanical resonator types. It is an ideal book for students and researchers working with micro and nanomechanical resonators.
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