The long-standing Kervaire invariant problem in homotopy theory arose from geometric and differential topology in the 1960s and was quickly recognised as one of the most important problems in the field. In 2009 the authors of this book announced a solution to the problem, which was published to wide acclaim in a landmark Annals of Mathematics paper. The proof is long and involved, using many sophisticated tools of modern (equivariant) stable homotopy theory that are unfamiliar to non-experts. This book presents the proof together with a full development of all the background material to make it accessible to a graduate student with an elementary algebraic topology knowledge. There are explicit examples of constructions used in solving the problem. Also featuring a motivating history of the problem and numerous conceptual and expository improvements on the proof, this is the definitive account of the resolution of the Kervaire invariant problem.
Well into the 20th century, one in four newborns failed to survive their first year of life. It was after World War II that medicine "discovered" the newborn as a human being entitled to medical treatment and prioritised care. Since its definition by Alexander Schaffer in 1960, neonatology has evolved into a mature, innovative, and ethical field. A large number of medical professionals' care for neonates, yet no definitive medical history of the newborn has been available until now. The Oxford Textbook of the Newborn: A Cultural and Medical History offers readers a unique and authoritative resource on the 3000-year history of the newborn within Western societies. Written by Professor Michael Obladen, a leading voice in neonatology, this book reflects on our perception of newborns, from the earliest days of human thought, through to the traces that remained in medieval life and persist today. It unearths ideas and evidence of societies' perceptions of newborns through a beautifully illustrated, impressive and often never-seen-before set of historical sources from libraries, archives, churches, excavation fields, and hospital charts around the world. Split into 8 sections which each cover aspects of the natural lifecycle of a neonate, this book demonstrates the impact of religion, law, ethics, philosophy and culture on newborns' quality of life, and covers fascinating topics such as the rites of passage for the newborn, infanticide, opium use, breastfeeding, and artificial feeding. Each chapter is written in an accessible style and includes high-quality historical illustrations which really bring the subject to life.
Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under lying defect in cell structural proteins.
Winner of the University of San Diego Outstanding Leadership Book Award 2012! Shortlisted for the British Psychological Society Book Award 2011! Shortlisted for the CMI (Chartered Management Institute) Management Book of the Year Award 2011–2012! According to John Adair, the most important word in the leader's vocabulary is "we" and the least important word is "I". But if this is true, it raises one important question: why do psychological analyses of leadership always focus on the leader as an individual – as the great "I"? One answer is that theorists and practitioners have never properly understood the psychology of "we-ness". This book fills this gap by presenting a new psychology of leadership that is the result of two decades of research inspired by social identity and self-categorization theories. The book argues that to succeed, leaders need to create, champion, and embed a group identity in order to cultivate an understanding of 'us' of which they themselves are representative. It also shows how, by doing this, they can make a material difference to the groups, organizations, and societies that they lead. Written in an accessible and engaging style, the book examines a range of central theoretical and practical issues, including the nature of group identity, the basis of authority and legitimacy, the dynamics of justice and fairness, the determinants of followership and charisma, and the practice and politics of leadership. The book will appeal to academics, practitioners and students in social and organizational psychology, sociology, political science and anyone interested in leadership, influence and power.
The definitive resource for designing and implementing evidence-based rehabilitation programs using therapeutic exercise Written and edited by top experts in their fields, Musculoskeletal Interventions provides the rehabilitation techniques, strategies, and considerations you need to effectively treat patients of all ages, abilities, and functional levels. With expanded coverage of movement systems, along with clinical pearls and hundreds of illustrations, this edition has been fully revised to reflect a contemporary movement system approach patient care. It focuses on the practical application of theory in a clinical setting, making it ideal for students and experienced physical therapists alike. Designed to make finding what you need quickly and easily, Musculoskeletal Interventions is organized into five sections: Foundations of the Rehabilitation Process Introduces the human movement system, the Guide to Physical Therapist Practice, and the clinical reasoning process Provides grounding on tissue healing, the Neuromuscular Scan Examination, pain, posture, and function Treating Physiologic Impairments During Rehabilitation Details general impairments that require attention throughout the rehabilitation process Covers muscle performance, endurance and aerobic capacity, mobility, range of motion, and neuromuscular control Tools of Rehabilitation Explains how to achieve optimal outcomes using various tools, including plyometric exercise, open- and closed-kinetic chain interventions, proprioceptive neuromuscular facilitation techniques, joint mobilization, postural stability and balance interventions, core stabilization training, aquatic therapy, functional movement screening, and more Interventions Strategies for Specific Regions Describes applications of techniques and interventions related to common movement-based, overuse, traumatic, and postoperative musculoskeletal dysfunction Provides guidance on conditions common to the shoulder complex, elbow, wrist, hand, digits, groin, hip, thigh, knee, lower leg, ankle, foot, and spine Discusses pathomechanics and injury mechanisms while focusing on rehabilitation strategies and concerns for specific injuries and providing example protocols Special Considerations for Specific Patient Populations Provides application of all previous intervention strategies and how these may need to be selected, adapted, and utilized for geriatric patients, pediatric patient, and physically active females Musculoskeletal Interventions is filled with features that help you understand and retain critical information. Learning aids include objectives, tales, clinical pearls, figures, video links, summary points, chapter-ending treatment guidelines, and references.
Here is a thorough, up-to-date survey of the physiological processes through which salt, water, and nutrients are absorbed or secreted by the intestinal tract, and of how these myriad processes are regulated. In twenty-five chapters, written by a team of leading experts, the volume addresses four main topics: the methodologies and basic principles of structure and function; intestinal ion transport; nutrient absorption; and macromolecular transport. Throughout, the contributors emphasize recent developments in the field--for example, neuroendocrine-immune cell interactions in the intestinal mucosa, the regulation of intestinal sodium transport, the cloning of the intestinal glucose carrier, the intestinal cytoskeleton, and the regulation of intestinal epithelial transport function by protein kinases and calmodulin. This is not only the fourth and final volume in the series; it is also the broadest, most contemporary approach to this important topic. As such, this book will be warmly welcomed--and often consulted--by student, scholars, professionals, and anyone researching intestinal absorptive mechanisms and their regulation.
A fresh look at school improvement from the perspective of professional development. Written to aid teachers in taking the initiative in identifying areas in need of improvement and finding ways of making the necessary changes.
Sport Nutrition, Third Edition, uses a physiological basis to provide an in-depth look at the science supporting nutrition recommendations. Students will come away with an understanding of nutrition as it relates to sport and the influence of nutrition on performance, training, and recovery.
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