By examining the development of economics in the 20th century, this book argues that the breakthroughs of post WWII general equilibrium theory and its rejection of utilitarianism and marginal productivity have been misunderstood. Mandler maintains that although earlier neoclassicism deserved criticism, current theory does not adequately address the problems the discarded concepts were designed to solve, and that intractable dilemmas therefore appear.
This important volume commences with an overview of the modes of action of defensive secondary metabolites, followed by detailed surveys of chemical defense in marine ecosystems, the biochemistry of induced defense, plant-microbe interactions and medical applications. A chapter is also included covering biotechnological aspects of producing valuable secondary metabolites in plant cell and organ cultures. This is a comprehensive and fully updated new edition, edited by Professor Michael Wink and including contributions from many internationally acknowledged experts in the field.
While there have been other books on Wal-Mart, none has provided scholarly economic analysis of the impact of this retail giant. "The Local Economic Impact of Wal-Mart" offers significant empirical evidence which highlights important questions.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
This volume reports on discussions among multiple stakeholders about ways they might help transform health care in the United States. The U.S. healthcare system consists of a complex network of decentralized and loosely associated organizations, services, relationships, and participants. Each of the healthcare system's component sectors-patients, healthcare professionals, healthcare delivery organizations, healthcare product developers, clinical investigators and evaluators, regulators, insurers, employers and employees, and individuals involved in information technology-conducts activities that support a common goal: to improve patient health and wellbeing. Implicit in this goal is the commitment of each stakeholder group to contribute to the evidence base for health care, that is, to assist with the development and application of information about the efficacy, safety, effectiveness, value, and appropriateness of the health care delivered.
A multi-disciplinary approach to transportation planningfundamentals The Transportation Planning Handbook is a comprehensive,practice-oriented reference that presents the fundamental conceptsof transportation planning alongside proven techniques. This newfourth edition is more strongly focused on serving the needs of allusers, the role of safety in the planning process, andtransportation planning in the context of societal concerns,including the development of more sustainable transportationsolutions. The content structure has been redesigned with a newformat that promotes a more functionally driven multimodal approachto planning, design, and implementation, including guidance towardthe latest tools and technology. The material has been updated toreflect the latest changes to major transportation resources suchas the HCM, MUTCD, HSM, and more, including the most current ADAaccessibility regulations. Transportation planning has historically followed the rationalplanning model of defining objectives, identifying problems,generating and evaluating alternatives, and developing plans.Planners are increasingly expected to adopt a moremulti-disciplinary approach, especially in light of the risingimportance of sustainability and environmental concerns. This bookpresents the fundamentals of transportation planning in amultidisciplinary context, giving readers a practical reference forday-to-day answers. Serve the needs of all users Incorporate safety into the planning process Examine the latest transportation planning softwarepackages Get up to date on the latest standards, recommendations, andcodes Developed by The Institute of Transportation Engineers, thisbook is the culmination of over seventy years of transportationplanning solutions, fully updated to reflect the needs of achanging society. For a comprehensive guide with practical answers,The Transportation Planning Handbook is an essentialreference.
Class and Power in the New Deal provides a new perspective on the origins and implementation of the three most important policies that emerged during the New Deal—the Agricultural Adjustment Act, the National Labor Relations Act, and the Social Security Act. It reveals how Northern corporate moderates, representing some of the largest fortunes and biggest companies of that era, proposed all three major initiatives and explores why there were no viable alternatives put forward by the opposition. More generally, this book analyzes the seeming paradox of policy support and political opposition. The authors seek to demonstrate the superiority of class dominance theory over other perspectives—historical institutionalism, Marxism, and protest-disruption theory—in explaining the origins and development of these three policy initiatives. Domhoff and Webber draw on extensive new archival research to develop a fresh interpretation of this seminal period of American government and social policy development.
In recent years, film has been one of the major genres within which the imaginaries involved in mapping the geopolitical world have been represented and reflected upon. In this book, one of America's foremost theorists of culture and politics treats those aspects of the "geopolitical aesthetic" that must be addressed in light of both the post cold war and post 9/11 world and contemporary film theory and philosophy. Beginning with an account of his experience as a juror at film festival’s, Michael J. Shapiro’s Cinematic Geopolitics analyzes the ways in which film festival space and both feature and documentary films function as counter-spaces to the contemporary "violent cartography" occasioned by governmental policy, especially the current "war on terror." Influenced by the cinema-philosophy relationship developed by Gilles Deleuze and the politics of aesthetics thinking of Jacques Ranciere, the book’s chapters examines a range of films from established classics like the Deer Hunter and the Battle of Algiers to contemporary films such as Dirty Pretty Things and the Fog of War. Shapiro’s use of philosophical and theoretical works makes this cutting edge examination of film and politics essential reading for all students and scholars with an interest in film and politics.
Recognized as the most prestigious, comprehensive text on Global Health for GRADUATE programs in public and global health. Global Health, Third Edition (formerly titled International Public Health) brings together contributions from the world's leading authorities into a single comprehensive text. It thoroughly examines the wide range of global health challenges facing low and middle income countries today and the various approaches nations adopt to deal with them. These challenges include measurement of health status, infectious and chronic diseases, injuries, nutrition, reproductive health, global environmental health and complex emergencies. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.
Sharing the costs of ill health is the mark of a civilised society. However, every society has limited healthcare resources, and must therefore make finely balanced decisions on how best to allocate them. The National Institute for Health and Clinical Excellence (NICE) has been responsible for the UK's health resource allocation for a decade. To inform its decisions, a Citizens Council of 30 members of the general public was established by NICE to gauge the underlying values of the society it serves. A number of national and international organisations and governments have asked NICE to share its experiences in establishing and running the Citizens Council, and encouraging and supporting patient involvement. As part of NICE's response, this book provides an up to date 'position statement' on the Citizens Council, an exploration of how patients interact with NICE and how their views are taken into account, and a national and international perspective on new issues facing the interaction between patients, the public and healthcare provision. 'Reading this volume will enable you, the reader, to assess how well NICE is acting as a means of fostering responsible public choice. I hope you profit from its chapters as much as I have.' - Albert Weale in his Foreword
Drawing on the work of the Roundtable on Evidence-Based Medicine, the 2007 IOM Annual Meeting assessed some of the rapidly occurring changes in health care related to new diagnostic and treatment tools, emerging genetic insights, the developments in information technology, and healthcare costs, and discussed the need for a stronger focus on evidence to ensure that the promise of scientific discovery and technological innovation is efficiently captured to provide the right care for the right patient at the right time. As new discoveries continue to expand the universe of medical interventions, treatments, and methods of care, the need for a more systematic approach to evidence development and application becomes increasingly critical. Without better information about the effectiveness of different treatment options, the resulting uncertainty can lead to the delivery of services that may be unnecessary, unproven, or even harmful. Improving the evidence-base for medicine holds great potential to increase the quality and efficiency of medical care. The Annual Meeting, held on October 8, 2007, brought together many of the nation's leading authorities on various aspects of the issues - both challenges and opportunities - to present their perspectives and engage in discussion with the IOM membership.
Inuit have among the highest suicide rates in the world - ten times the national average. Inuit narratives of suicide provide clues as to what can and in some cases has been done to combat the problem, but until recently they have not circulated far beyond Inuit communities themselves. At the same time, academic researchers have studied suicide among Indigenous peoples, but have stopped short of analyzing narrative accounts for their themes of cultural survival. Based on two decades of participatory action and ethnographic research, The Return of the Sun is a historical and anthropological examination of suicide among Inuit youth in Arctic Canada. Conceptualizing suicide among Inuit as a response to colonial disruption of family and interpersonal relationships and examining how the community has addressed the issue, Kral draws on research from psychology, anthropology, Indigenous studies, and social justice to understand and address this population. Central to the book are narrative accounts by Inuit of their experiences and perceptions of suicide, and the lives of youth and their community action for change. As these Indigenous community success stories have not previously been widely retold, The Return of the Sun gives voice to a historically ignored community. Kral also locates this community action within the larger Inuit movement toward self-determination and self-governance. This important volume will be of interest to a broad range of social scientists, as well as researchers and practitioners in the mental health fields.
The Orthopaedic Clinical Handbook is a pocket guide for students in any orthopedic course, including physicians, physical therapists and assistants, chiropractors, and athletic trainers. This useful resource is organized in a manner that is helpful for both students and clinicians. the reader will find the information they need easily, as the information is organized by body regions, and includes medical screening differential diagnosis tables, origin, insertion, nerve supply and action of muscles. Suggestions for evaluation, post surgical rehab protocols, and evidence-based parameters for mod
My inspiration for doing this journal and writing this book is basically an outlet to have a say. Never have been one to get up in front of a group of people and speak. I always had this excellent memory and writing was a way for me to get it out and so, I decided to do just that. So many times down through the years I was told by friends and even some professional people, I should write a book. My attempt to live in a normal family, from the time I was very young, it was never destined to happen. Thats just the way it was, a higher power was and is the ruler over that. The thing that most people take for granted, family, has always been a missing link in my life. As a result, I have to talk mostly about experiences; things; hobbies; friends etc. and that is why you will find the absence of family in the context of my story. I would have loved to have had family to be a part of my life. When I retired from the Teamster via the BOEING Co. in October 1995, I already had work to go to immediately and worked clear into 2002. My Mother passed away in August 1999 and she had lived a full life to 95 years of age. Even though I had 3 daughters living and doing their thing in different parts of the country, at that particular time, my relationship with 2 of them was minimal and non-existent with the 3rd. After having moved up to Camano Island in 2003 and planning to stay there permanently, well.it turned out that wasnt what I really wanted after I got there and only lived there for 10 months, sold that house, packed up all my stuff and hauled it to Texas. I had decided I would make an attempt to live near my oldest daughter. It would at least give me a chance to maybe have a bond with my flesh and blood once in awhile. It worked in the very short term till she changed jobs and moved to Dallas. Too little, too late, it was not in the cards. At this point my oldest daughter and I have a pleasant relationship even though we see each other maybe twice a year. Flying up to my home area in Washington state once or twice a year is one of the things I really look forward to. I have some real solid friends in Washington that will always be my best friends. Im really a Lucky Guy! Mike Hicks
Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.
This book addresses two issues related to the structure of local government: the determinants of consolidation and the potential impact of consolidation on local government spending. This is a narrow undertaking and leaves important elements of local government reform for future analysis. The study's primary foci are examining the factors that influence city-county consolidation, considering the impact of city-county consolidation on local government spending, and estimating the potential savings that could result from the scale economies and efficiency gains from consolidating local government units. While other regions of the United States are considered in this study, but the analysis focuses primarily on the Midwest where population declines and changes in the employment base and state policies (such as property tax caps in Indiana) have had dramatic effects on the fiscal viability of local governments. The current economic climate, along with policy changes related to property tax restructuring in many states, has led to substantial reductions in local governments' budgets. As a result, many local governments are in crisis and are considering some level of consolidation. Statistical methods and data on consolidation referendum attempts in the United States since 1970 are used to test whether governments that have consolidated (i.e., voters approved the consolidation referendum) had higher spending prior to their consolidation (as measured by local government employment rates, payrolls, and expenditures) compared to the average local government in the state. The effects of city-county consolidation are explored; using consolidation referendum data, the impact of consolidation on local government employment rates, payrolls, and expenditures is examined. The influence of consolidation on economic development is also investigated with some interesting results. The study also used two methods to estimate the savings from government consolidation and presents aggregate models to examine the potential savings from economies of scale and efficiency improvements. The book also helpfully provides a helpful discussion of the economies of scale and efficiency for several functional areas, including police and fire protection, sewerage, solid waste, public welfare, administration, health, education, and libraries. This book will be an essential resource for political scientists and policy makers interested in American government. Written in a highly accessible manner, it will also be a valuable read for students and general readers.
Benedictin was prescribed to more than thirty-five million American women from its introduction in 1956 until 1983, when it was withdrawn from the market. The drug's manufacturer, Merrill Dow Pharmaceuticals, a major U.S. pharmaceutical firm, joined a list of other companies whose product liabilities would result in precedent-setting litigation. Before it was over, the Benedictin litigation would involve 2,000 claimants over a fifteen-year period. Michael D. Green offers a comprehensive overview of the Benedictin case and highlights many of the key issues in mass toxic substances litigation, comparing individual and collective forms of litigation, and illustrating the misunderstandings between scientists and lawyers about the role of science in providing evidence for the legal system.
Examines the history of the idea of development, and doctrines governments have employed to practice development policy. Beginning with the 19th century "invention" of modern development, the authors discuss Karl Marx's critique of development and the crea
Patient safety and quality improvement in health care remain a global priority. Subpar performance in health care, however, is still common more than a decade after the christening of patient safety in Africa. The core principle of safety and quality improvement systems is to identify and assess the root cause of failures in order to learn from them and devise a means to improve and to avoid recurrence. This book is designed to encourage, facilitate and empower healthcare workers in the development and implementation of strategically driven patient safety and quality improvement initiatives for safer healthcare systems and healthcare facilities in low- and middle-income countries (LMICs) of Africa. It also highlights some of the profound challenges and barriers to designing and implementing patient safety and quality improvement interventions or programmes in the region and reiterates the need to remain focused and determined to work out solutions with confidence and overcome these barriers. In the book, chapters highlight six essential components crucial for achieving evolutionary progress in safety and quality improvement in a healthcare system: Standard operating procedure Audit Research Safety management Quality management Evaluation Practical steps in planning and conducting these six essential components are outlined with some specific features to aid learning and facilitate their implementation. The authors have experience and expertise in the medical practice gained in Africa and a decade of knowledge and experience from consultancy work in safety and quality improvement in health care within and outside the region. Essentials for Quality and Safety Improvement in Health Care: A Resource for Developing Countries is authored for both medical professionals and those from other professions who are interested in and enthusiastic about patient safety and healthcare quality and therefore willing to build a career in this field. It is relevant to all health institutions, health and non-health workers, and can be used as a checklist while rendering quality and safe health care.
The Teaching and Learning Playbook is a book and online resource containing more than 100 techniques that teachers and school leaders can use to drive improvements in their schools. Each technique includes a summary of what the technique is, why it is important, the effect size and a four-step guide to how it should be performed. The Playbook provides a unique tool for teachers to identify how they can improve their teaching, and practise with absolute clarity on what they need to do next. All techniques are accompanied by a video to show the technique in action and spotlight the four key elements with detailed audio commentary to make it easier for teachers to replicate. These can all be found on the website: www.teachingandlearningplaybook.com Codifying the key skills for every teacher to get better and for every school leader to drive improvements in their school, the Playbook covers: Routines for Learning Questioning and Checking for Understanding Modelling, Explaining and Feeding Back Resilience, Independence and Retrieval Curriculum Beyond the Subject Classroom This essential resource provides a clear framework for teachers and school leaders to improve teaching and learning. Simple to use and easily integrated into CPD and coaching programmes, the Playbook will take your teaching to the next level.
Here's a one-of-a-kind sourcebook on who's who and what's what in American business today. Arranged alphabetically by type of company, it offers a diverse assortment of listings crucial in reaching CEOs, VPs, and other key executives in the nation's top 1,000 companies.
Since scaling of CMOS is reaching the nanometer area serious limitations enforce the introduction of novel materials, device architectures and device concepts. Multi-gate devices employing high-k gate dielectrics are considered as promising solution overcoming these scaling limitations of conventional planar bulk CMOS. Variation Aware Analog and Mixed-Signal Circuit Design in Emerging Multi-Gate CMOS Technologies provides a technology oriented assessment of analog and mixed-signal circuits in emerging high-k and multi-gate CMOS technologies.
This book presents the first unified conceptual and statistical framework for understanding the evolution of reproductive strategies. Using the concept of the opportunity for sexual selection, the authors illustrate how and why sexual selection, though restricted to one sex and opposed in the other, is one of the strongest and fastest of all evolutionary forces. They offer a statistical framework for studying mating system evolution and apply it to patterns of alternative mating strategies. In doing so, they provide a method for quantifying how the strength of sexual selection is affected by the ecological and life history processes that influence females' spatial and temporal clustering and reproductive schedules. Directly challenging verbal evolutionary models that attempt to explain reproductive behavior without quantitative reference to evolutionary genetics, this book establishes a more solid theoretical foundation for the field. Among the weaknesses the authors find in the existing data is the apparent ubiquity of condition-dependent mating tactics. They identify factors likely to contribute to the evolution of alternative mating strategies--which they argue are more common than generally believed--and illustrate how to measure the strength of selection acting on them. Lastly, they offer predictions on the covariation of mating systems and strategies, consider the underlying developmental biology behind male polyphenism, and propose directions for future research. Informed by genetics, this is a comprehensive and rigorous new approach to explaining mating systems and strategies that will influence a wide swath of evolutionary biology.
Facing threats like climate change and nuclear warfare, science fiction authors have conjured apocalyptic scenarios of human extinction. Can such gloomy fates help us make sense of our contemporary crises? How important is the survival of our species if we wind up battling for an Earth that has become an unhabitable hellscape? What other possible futures do narratives of the end of humanity allow us to imagine? Michael Bérubé explores the surprising insights of classic and contemporary works of SF that depict civilizational collapse and contemplate the fate of Homo sapiens. In a lively, conversational style, he considers novels by writers including Ursula K. Le Guin, Margaret Atwood, Liu Cixin, Philip K. Dick, and Octavia Butler, as well as films that feature hostile artificial intelligence, such as 2001: A Space Odyssey, Blade Runner, and the Terminator and Matrix franchises. Bérubé argues that these works portray a future in which we have become able to see ourselves from the vantage point of something other than the human. Though framed by the possibility of human extinction, they are driven by a vision of the “ex-human”—a desire to imagine that another species is possible. For all science fiction readers worried about the fate of humanity, The Ex-Human is an entertaining yet sobering account of how key novels and films envision the world without us.
Turn to the field's definitive text for a thoroughunderstanding of the clinical and scientific aspects of pulmonary medicine Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with 270 contributing authors, includes over 2,000 illustrations, 60 videos, and 18,000 references. The book opens with a comprehensive overview of the scientific basis of lung function in health and disease. It then provides detailed coverage of the broad array of diseases and disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms,respiratory infections, and respiratory failure, among others. The Fifth Edition has been completely updated to reflect the many advancements that have been made in pulmonary medicine over the past few years, including: Molecular development of the lung Stem cells and respiratory disease Genetics of pulmonary disease and the growth of personalized medicine Technical advances in lung transplantation Growth in immunology and immunosuppressive management Diagnosis and treatment of pulmonary hypertension Circadian rhythms and sleep biology Rapid evolution in lung imaging techniques, including functional imaging Contemporary interventional bronchoscopic techniques You will also find state-of-the-art coverage of thelatest topics in critical care medicine, including: Early diagnosis and management of sepsis Multiple organ dysfunction syndrome (MODS) Acute respiratory distress syndrome (ARDS) Management of agitation and delirium in the ICU The newly defined entity of "chronic critical illness
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.