Michael J. Dennis's Books

Cognitive, Conative and Behavioral Neurology

An Evolutionary Perspective

By: Michael Hoffmann

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Cognitive, Conative and Behavioral Neurology

An Evolutionary Perspective

By: Michael Hoffmann

This ground breaking title presents the many different neurologic syndromes and vastly expanding data in the brain sciences from an evolutionary, or neuro-archeological, perspective, as well as a clinical one. The neuro-archeological perspective offers a more thorough picture of the field – providing hindsight that leads to great insight and foresight. It thus provides the reader with the core foundational aspects of many perplexing neurologic syndromes. Authored by a noted authority in cognitive neurology and including ample tables, diagrams and images, the book covers the full range of behavioral neurological, psychological and neuropsychiatric syndromes, as well as their underlying disease states, relevant neuropsychological tests and contemporary neuroimaging, both structural and functional. The evolutionary approach offers a comprehensive, novel, and completely updated overview of each topic. An invaluable title unlike any other in the field, Cognitive, Conative and Behavioral Neurology: An Evolutionary Perspective is a landmark resource and will be of great interest to neurologists, psychiatrists, neuroscientists, and trainees in all fields.

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333

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Springer

Published Date

ISBN 10

3319331817

ISBN 13

9783319331812

Do Freemasons Worship Lucifer?

By: Kedar Griffo,Michael Berkley

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Do Freemasons Worship Lucifer?

By: Kedar Griffo,Michael Berkley

Freemasons are accused of worshipping Lucifer. This book examines the concept of Lucifer, and its effect on everyday life. There is more than meets the eye, so we present the true purpose and meaning of Lucifer.

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340

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Lulu.com

Published Date

ISBN 10

1257845349

ISBN 13

9781257845347

Levin and O'Neal's the Diabetic Foot

By: Marvin E. Levin,John H. Bowker,Michael A. Pfeifer

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Levin and O'Neal's the Diabetic Foot

By: Marvin E. Levin,John H. Bowker,Michael A. Pfeifer

Fully updated, now in full color, this latest edition of Levin and O'Neal's The Diabetic Foot provides diagnostic and management information for the challenging problems faced by patients with diabetic foot problems. The book has a team care focus and offers tips and pearls in every chapter.

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648

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323041450

ISBN 13

9780323041454

Quantitative Molecular Pharmacology and Informatics in Drug Discovery

By: Michael Lutz,Terry Kenakin

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Quantitative Molecular Pharmacology and Informatics in Drug Discovery

By: Michael Lutz,Terry Kenakin

Quantitative Molecular Pharmacology and Informatics in Drug Discovery Michael Lutz, Section Head, Cheminformatics Group and Terry Kenakin, Principal Research Scientist, Glaxo Wellcome Research and Development, Research Triangle Park, NC, USA Quantitative Molecular Pharmacology and Informatics in Drug Discovery combines pharmacology, genetics and statistics to provide a complete guide to the modern drug discovery process. The book discusses the pharmacology of drug testing and provides a detailed description of the statistical methods used to analyze the resulting data. Application of genetic and genomic tools for identification of biological targets is reviewed in the context of drug discovery projects. Covering both the theoretical principles upon which the techniques are based and the practicalities of drug discovery, this informative guide. * outlines in step-by-step detail the advantages and disadvantages of each technology and approach and links these to the type of chemical target being sought after in the drug discovery process; and, * provides excellent demonstrations of how to use powerful pharmacological and statistical tools to optimize high-throughput screening assays. Written by two internationally known and well-regarded experts, this book is an essential reference for research and development scientists working in the pharmaceutical and biotechnology industries. It will also be useful for postgraduates studying pharmacology and applied statistics.

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438

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John Wiley & Sons

Published Date

ISBN 10

0471988618

ISBN 13

9780471988618

Cerebral Ischemia

By: Werner Hacke,Michael Hennerici,Herman J. Gelmers,Günter Krämer

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Cerebral Ischemia

By: Werner Hacke,Michael Hennerici,Herman J. Gelmers,Günter Krämer

Despite a worldwide reduction in its incidence, stroke remains one of the most common diseases generally and the most important cause of premature and persistent disability in the industrialized countries. The most frequent cause of stroke is a localized disturbance of cerebral circulation, i.e., cerebral ischemia. Less common are spon taneous intracerebral and subarachnoid hemorrhages and sinus ve nous thromboses. The introduction of new diagnostic procedures such as cranial computed tomography, magnetic resonance imaging, digi tal subtraction radiologic techniques, and various ultrasound tech niques has led to impressive advances in the diagnosis of stroke. Through the planned application of these techniques, it is even possible to identify the pathogenetic mechanisms underlying focal cerebral ischemia in humans. However, these diagnostic advances have made the gap between diagnostic accuracy and therapeutic implications even greater than before. This fact can be easily explained. In the past, therapeutic studies had to be based on the symptoms and temporal aspects of stroke; it was impossible for early investigations to consider the various pathogeneses of cerebral ischemia. Inevitably, stroke patients were treated as suffering from a uniform disease.

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345

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Springer Science & Business Media

Published Date

ISBN 10

3642755488

ISBN 13

9783642755484

Stroke E-Book

Pathophysiology, Diagnosis, and Management

By: J. P. Mohr,Philip A. Wolf,Michael A. Moskowitz,Marc R Mayberg,Rudiger Von Kummer

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Stroke E-Book

Pathophysiology, Diagnosis, and Management

By: J. P. Mohr,Philip A. Wolf,Michael A. Moskowitz,Marc R Mayberg,Rudiger Von Kummer

First published in 1986 under the editorial direction of Dr. Henry J.M. Barnett, Stroke: Pathophysiology, Diagnosis, and Management continues to provide the dependable, current answers you need to effectively combat the increasing incidence of this disease. Dr. J.P. Mohr, together with new associate editors Philip A. Wolf, James C. Grotta, Michael A. Moskowitz, Marc Mayberg, and Rüdiger von Kummer as well as a multitude of expert contributors from around the world, offer you updated and expanded coverage of mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more, equipping you to understand the latest scientific discoveries and make effective use of the newest approaches to diagnosis and treatment. Gain fresh perspectives and up-to-date insights from the world’s leading authorities on the pathophysiology, diagnosis, and management of stroke. Access the comprehensive, expert clinical guidance you need to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Make efficient and accurate diagnoses with the aid of abundant full-color CT images and pathology slides. Stay up to date on hot topics such as mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more.

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1513

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1437737803

ISBN 13

9781437737806

Neurologic Emergencies, An Issue of Emergency Medicine Clinics of North America

By: Jonathan A. Edlow,Michael K. Abraham

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Neurologic Emergencies, An Issue of Emergency Medicine Clinics of North America

By: Jonathan A. Edlow,Michael K. Abraham

This issue of Emergency Medicine Clinics focuses on Neurologic Emergencies. Articles include: Headache; Back Pain; Dizziness; Generalized Weakness; Initial Diagnosis and Management of Coma; Neuro-ophthalmology; Diagnosis of Acute Ischemic Stroke; Treatment of Acute Ischemic Stroke; Acute Hemorrhagic Stroke; Status Epilepticus; Diagnosis and Emergency Management of Subarachnoid Hemorrhage and more!

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321

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Elsevier Health Sciences

Published Date

ISBN 10

0323477003

ISBN 13

9780323477000

The Women of Hammer Horror

A Biographical Dictionary and Filmography

By: Robert Michael “Bobb” Cotter

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The Women of Hammer Horror

A Biographical Dictionary and Filmography

By: Robert Michael “Bobb” Cotter

The Hammer studio is best known for its horror film output from the mid-1950s through the 1970s. This book provides facts about the hundreds of actresses who appeared in those films, including ones released in the twenty-first century by a resurgent Hammer. Each woman's entry includes her Hammer filmography, a brief biography if available, and other film credits in the horror genre. The book is illustrated with more than 60 film stills and posters.

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249

Publisher

McFarland

Published Date

ISBN 10

1476602018

ISBN 13

9781476602011

Image and Video Matting

A Survey

By: Jue Wang,Michael F. Cohen

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Image and Video Matting

A Survey

By: Jue Wang,Michael F. Cohen

Image and Video Matting: A Survey provides a comprehensive review of existing image and video matting algorithms and systems, with an emphasis on the advanced techniques that have been recently proposed. Various methods are described and contrasted and finally tested against a uniform set of examples.

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Now Publishers Inc

Published Date

ISBN 10

1601981341

ISBN 13

9781601981349

Mr. Mikey's Video Views; Volume One

By: J. Michael Dlugos

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Mr. Mikey's Video Views; Volume One

By: J. Michael Dlugos

Mr. Mikey's Video Views started as a response to the three-line reviews found in most review guides, and the "self-serving" and exceedingly picky reviews written by most "popular critics." Mr. Mikey is a movie lover, and has fun and enjoys virtually every movie he sees. His reviews reflect this love of movies.

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234

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Trafford Publishing

Published Date

ISBN 10

1552123162

ISBN 13

9781552123164

Lishman's Organic Psychiatry

A Textbook of Neuropsychiatry

By: Daniel David,Simon Fleminger,Michael Kopelman,Simon Lovestone,John Mellers

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Lishman's Organic Psychiatry

A Textbook of Neuropsychiatry

By: Daniel David,Simon Fleminger,Michael Kopelman,Simon Lovestone,John Mellers

For three decades psychiatrists have turned to Lishman's Organic Psychiatry as the standard neuropsychiatry reference. It stood as the last great single author reference text in medicine, a combination of meticulous, exhaustive research conveyed in a beautifully clear style. Now the mantle has been passed to a group of five distinguished authors and it is to their considerable credit that the attributes which made Organic Psychiatry such a distinctive voice remain. The fourth Edition of Lishman's Organic Psychiatry is a rich blend of detailed clinical inquiry and up to date neuroscience. It should be on every psychiatrist;s book shelf." —Anthony Feinstein, MPhil, PhD., FRCP, Professor, Department of Psychiatry, University of Toronto, Canada Over the past 30 years, thousands of physicians have depended on Lishman's Organic Psychiatry. Its authoritative and reliable clinical guidance was - and still is - beyond compare. The new edition of this classic textbook has now been extensively revised by a team of five authors, yet it follows the tradition of the original single-authored book. It continues to provide a comprehensive review of the cognitive, emotional and behavioural consequences of cerebral disorders and their manifestations in clinical practice. Enabling clinicians to formulate incisive diagnoses and appropriate treatment strategies, Lishman's Organic Psychiatry is an invaluable source of information for practising psychiatrists, neurologists and trainees. This new edition: covers recent theoretical and clinical developments, with expanded sections on neuropsychology and neuroimaging includes a new chapter on sleep disorders whilst the chapters on Alzheimer's disease and related dementias, Epilepsy, Movement disorders and Traumatic brain injury have been extensively revised reflecting the greatly improved understanding of their underlying pathophysiologies showcases the huge advances in brain imaging and important discoveries in the fields of molecular biology and molecular genetics has been enhanced with the inclusion of more tables and illustrations to aid clinical assessment incorporates important diagnostic tools such as magnetic resonance brain images.

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961

Publisher

John Wiley & Sons

Published Date

ISBN 10

144435681X

ISBN 13

9781444356816

Lishman's Organic Psychiatry

A Textbook of Neuropsychiatry

By: Anthony David,Simon Fleminger,Michael Kopelman,Simon Lovestone,John Mellers

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Lishman's Organic Psychiatry

A Textbook of Neuropsychiatry

By: Anthony David,Simon Fleminger,Michael Kopelman,Simon Lovestone,John Mellers

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956

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John Wiley & Sons

Published Date

ISBN 10

1444316818

ISBN 13

9781444316810

Branch-and-Bound Applications in Combinatorial Data Analysis

By: Michael J. Brusco,Stephanie Stahl

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Branch-and-Bound Applications in Combinatorial Data Analysis

By: Michael J. Brusco,Stephanie Stahl

There are a variety of combinatorial optimization problems that are relevant to the examination of statistical data. Combinatorial problems arise in the clustering of a collection of objects, the seriation (sequencing or ordering) of objects, and the selection of variables for subsequent multivariate statistical analysis such as regression. The options for choosing a solution strategy in combinatorial data analysis can be overwhelming. Because some problems are too large or intractable for an optimal solution strategy, many researchers develop an over-reliance on heuristic methods to solve all combinatorial problems. However, with increasingly accessible computer power and ever-improving methodologies, optimal solution strategies have gained popularity for their ability to reduce unnecessary uncertainty. In this monograph, optimality is attained for nontrivially sized problems via the branch-and-bound paradigm. For many combinatorial problems, branch-and-bound approaches have been proposed and/or developed. However, until now, there has not been a single resource in statistical data analysis to summarize and illustrate available methods for applying the branch-and-bound process. This monograph provides clear explanatory text, illustrative mathematics and algorithms, demonstrations of the iterative process, psuedocode, and well-developed examples for applications of the branch-and-bound paradigm to important problems in combinatorial data analysis. Supplementary material, such as computer programs, are provided on the world wide web. Dr. Brusco is a Professor of Marketing and Operations Research at Florida State University, an editorial board member for the Journal of Classification, and a member of the Board of Directors for the Classification Society of North America. Stephanie Stahl is an author and researcher with years of experience in writing, editing, and quantitative psychology research.

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248

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Springer Science & Business Media

Published Date

ISBN 10

0387250379

ISBN 13

9780387250373

Laws, Men and Machines

Modern American Government and the Appeal of Newtonian Mechanics

By: Michael Foley

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Laws, Men and Machines

Modern American Government and the Appeal of Newtonian Mechanics

By: Michael Foley

First published in 1990, Laws, Men and Machines is an original interpretation of the lasting influence that Newtonian mechanics has had on the design and operation of the American political system. The author argues that it is this mechanistic tradition that now instinctively shapes the way we conceive of, analyse, and evaluate American politics, and that the Newtonian conception of the world still finds expression in the 'checks and balances' of the American system.

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344

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Routledge

Published Date

ISBN 10

1317829158

ISBN 13

9781317829157

Proportionality in International Law

By: Michael Newton,Larry May

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Proportionality in International Law

By: Michael Newton,Larry May

Proportionality is intimately linked to the overarching concepts of self-defense, lawful force, and the controlled application of violence. It is one of the most visible facets of humanitarian law designed to reduce unnecessary human suffering and avoid excessive damage to property, and the natural environment. However, its application has come under renewed scrutiny and sustained controversy as a result of wars against non-state actors and from the extensive use of drones, human shields, cyber war techniques, and counterinsurgency tactics. Proportionality in International Law critically assesses the law of proportionality in normative terms combining abstract philosophical and legal analysis with highly emotive contemporary combat cases. The principle of proportionality permits actions that are logically linked to the intended goal, and thus defines the permissible boundaries for the initiation and conduct of modern wars. The case studies discussed in this book are predominantly from the perspective of those who make decisions in the midst of armed conflict, bringing analytic rigor to the debates as well as sensitivity to facts on the ground. The authors analyze modern usages of proportionality across a wide range of contexts enabling a more complete comprehension of the values that it preserves. This book contrasts the applications of proportionality in both jus ad bellum (the law and morality of resort to force) and within jus in bello (the doctrines applicable for using force in the midst of conflicts). Proportionality in International Law provides the reader with a unique interdisciplinary approach, offering practitioners and policymakers alike greater clarity over how proportionality should be understood in theory and in practice.

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354

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Oxford University Press

Published Date

ISBN 10

0199355045

ISBN 13

9780199355044

Dispute Resolution

Beyond the Adversarial Model

By: Carrie J. Menkel-Meadow,Lela Porter Love,Andrea Kupfer Schneider,Michael L. Moffitt

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Dispute Resolution

Beyond the Adversarial Model

By: Carrie J. Menkel-Meadow,Lela Porter Love,Andrea Kupfer Schneider,Michael L. Moffitt

Dispute Resolution: Beyond the Adversarial Model, Third Edition provides a comprehensive look at the current state of ADR. For each area of Negotiation, Mediation, Arbitration, and Hybrid processes, the text incorporates four key aspects: the theoretical framework defining the process; the skills needed to practice it; the ethical issues implicated in its use and how to counsel users of such processes; and legal and policy analyses, with questions and problems within the text. New to the Third Edition: A shorter, more compact book designed to be student-friendly Exercises and discussion problems throughout Designed for one chapter to be covered each week of a typical ADR course The latest on Online Dispute Resolution, Dispute System Design, Supreme Court decisions on arbitration, and empirical work on mediation and negotiation Professors and students will benefit from: Comprehensive, current coverage. The theory, skills, ethical issues, and legal and policy analyses relevant to all key areas of contemporary ADR practice—Negotiation, Mediation, Arbitration, and hybrid and multi-party processes and their appropriate uses—are thoroughly covered using a rich range of up-to-date cases and readings. Authored by the leading scholars and teachers in the field of Dispute Resolution. The authors are award winning and recognized for their scholarship, teaching, practice, policy making, and standards drafting throughout the wide range of particular ADR processes. Practical approach to problem-solving. The text engages students as active participants in resolving human and legal problems, using individual or combined resolution processes in varying gender, race, and cultural contexts. International and multi-party dispute resolution. These important, high-interest contexts and applications are thoroughly covered in discrete chapters. Readings balance theory and theory-in-use. Readings include cases, behaviorally and critically based articles, examples, empirical studies, and relevant statutory and other regulatory material to illuminate the challenge of balancing rules and laws with the economic and emotional constraints inherent in disputes. Challenging, relevant readings. The text includes a wide range of perspectives, from Fisher, Ury, and Patton’s Getting to Yes, Raiffa’s Art and Science of Negotiation, and materials on modern deliberative democracy, group facilitation and decision making, counseling clients about uses of ADR, enforcement of negotiation, and mediation agreements. Key cases include AT&T v. Concepcion and other recent Supreme court cases on arbitration. Teaching materials include: Numerous role-plays and simulations for skills development Suggested teaching exercises, syllabi and “answers” to problem boxes found in text Recommendations for supplemental materials, such as videos and transcripts Examination and paper suggestions for each chapter

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819

Publisher

Aspen Publishing

Published Date

ISBN 10

1543803105

ISBN 13

9781543803105

Thinking Developmentally from Constructivism to Neuroconstructivism

Selected Works of Annette Karmiloff-Smith

By: Annette Karmiloff-Smith,Michael S. C. Thomas,Mark H Johnson

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Thinking Developmentally from Constructivism to Neuroconstructivism

Selected Works of Annette Karmiloff-Smith

By: Annette Karmiloff-Smith,Michael S. C. Thomas,Mark H Johnson

In the World Library of Psychologists series, international experts present career-long collections of what they judge to be their finest pieces - extracts from books, key articles, salient research findings, and their major practical theoretical contributions. This influential volume of papers, chosen by Professor Annette Karmiloff-Smith before she passed away, recognises her major contribution to the field of developmental psychology. Published over a 40-year period, the papers included here address the major themes that permeate through Annette’s work: from typical to atypical development, genetics and computation modelling approaches, and neuroimaging of the developing brain. A newly written introduction by Michael S. C. Thomas and Mark H. Johnson gives an overview of her research journey and contextualises her selection of papers in relation to changes in the field over time. Thinking Developmentally from Constructivism to Neuroconstructivism: Selected Works of Annette Karmiloff-Smith is of great interest to researchers and postgraduates in child development specialising in atypical development, developmental disorders, and developmental neuroscience. It also has appeal to clinical neuropsychologists and rehabilitation professionals.

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314

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Routledge

Published Date

ISBN 10

1315516675

ISBN 13

9781315516677

In the Eye of All Trade

Bermuda, Bermudians, and the Maritime Atlantic World, 1680-1783

By: Michael J. Jarvis

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In the Eye of All Trade

Bermuda, Bermudians, and the Maritime Atlantic World, 1680-1783

By: Michael J. Jarvis

In an exploration of the oceanic connections of the Atlantic world, Michael J. Jarvis recovers a mariner's view of early America as seen through the eyes of Bermuda's seafarers. The first social history of eighteenth-century Bermuda, this book profiles how one especially intensive maritime community capitalized on its position "in the eye of all trade." Jarvis takes readers aboard small Bermudian sloops and follows white and enslaved sailors as they shuttled cargoes between ports, raked salt, harvested timber, salvaged shipwrecks, hunted whales, captured prizes, and smuggled contraband in an expansive maritime sphere spanning Great Britain's North American and Caribbean colonies. In doing so, he shows how humble sailors and seafaring slaves operating small family-owned vessels were significant but underappreciated agents of Atlantic integration. The American Revolution starkly revealed the extent of British America's integration before 1775 as it shattered interregional links that Bermudians had helped to forge. Reliant on North America for food and customers, Bermudians faced disaster at the conflict's start. A bold act of treason enabled islanders to continue trade with their rebellious neighbors and helped them to survive and even prosper in an Atlantic world at war. Ultimately, however, the creation of the United States ended Bermuda's economic independence and doomed the island's maritime economy.

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703

Publisher

UNC Press Books

Published Date

ISBN 10

0807895881

ISBN 13

9780807895887

Ideology Studies

New Advances and Interpretations

By: Michael Freeden

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Ideology Studies

New Advances and Interpretations

By: Michael Freeden

This book comprehensively collects the thinking - over the last 25 years - of one the most important contemporary scholars in the field of ideology studies. Clearly organised, it expounds on the changing nature of the sub-discipline, its components and methods of investigation. As such, it serves the need for a general, well-informed identification and elaboration of thematic possibilities in current ideology studies and represents the most developed and productive methodological approach to the study of ideologies in the last three decades. Freeden presents ideology studies as an evolving and vibrant field, encountering and surmounting a series of challenges in its successful path towards recognition as a fully legitimate and respected branch of political theory. This book will be of key interest to students and scholars of political ideologies, political theory, political philosophy and more broadly to sociology, political science, anthropology, human geography, international studies and the humanities.

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218

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Routledge

Published Date

ISBN 10

1000469433

ISBN 13

9781000469431

Economy in Society

Essays in Honor of Michael J. Piore

By: Michael J. Piore

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Economy in Society

Essays in Honor of Michael J. Piore

By: Michael J. Piore

Prominent economists discuss internal labor markets, the dynamics of immigration, labor market regulation, and other key topics in the work of Michael J. Piore. In Economy in Society, five prominent social scientists honor Michael J. Piore in original essays that explore key topics in Piore's work and make significant independent contributions in their own right. Piore is distinctive for his original research that explores the interaction of social, political, and economic considerations in the labor market and in the economic development of nations and regions. The essays in this volume reflect this rigorous interdisciplinary approach to important social and economic questions. M. Diane Burton's essay extends our understanding of internal labor markets by considering the influence of surrounding firms; Natasha Iskander builds on Piore's theory of immigration with a study of Mexican construction workers in two cities; Suzanne Berger highlights insights from Piore's work on technology and industrial development; Andrew Schrank takes up the theme of regulatory discretion; and Charles Sabel discusses theories of public bureaucracy.

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Page Count

175

Publisher

MIT Press

Published Date

ISBN 10

0262018241

ISBN 13

9780262018241

Drug Repositioning

Bringing New Life to Shelved Assets and Existing Drugs

By: Michael J. Barratt,Donald E. Frail

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Drug Repositioning

Bringing New Life to Shelved Assets and Existing Drugs

By: Michael J. Barratt,Donald E. Frail

The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational challenges and opportunities that drug repositioning offers. Readers will learn how to perform the latest experimental and computational methods that support drug repositioning, and detailed case studies throughout the book demonstrate how these methods fit within the context of a comprehensive drug repositioning strategy. Drug Repositioning is divided into three parts: Part 1, Drug Repositioning: Business Case, Strategies, and Operational Considerations, examines the medical and commercial drivers underpinning the quest to reposition existing drugs, guiding readers through the key strategic, technical, operational, and regulatory decisions needed for successful drug repositioning programs. Part 2, Application of Technology Platforms to Uncover New Indications and Repurpose Existing Drugs, sets forth computational-based strategies, tools, and databases that have been designed for repositioning studies, screening approaches, including combinations of existing drugs, and a look at the development of chemically modified analogs of approved agents. Part 3, Academic and Non-Profit Initiatives & the Role of Alliances in the Drug Repositioning Industry, explores current investigations for repositioning drugs to treat rare and neglected diseases, which are frequently overlooked by for-profit pharmaceutical companies due to their lack of commercial return. The book's appendix provides valuable resources for drug repositioning researchers, including information on drug repositioning and reformulation companies, databases, government resources and organizations, regulatory agencies, and drug repositioning initiatives from academia and non-profits. With this book as their guide, students and pharmaceutical researchers can learn how to use drug repositioning techniques to extend the lifespan and applications of existing drugs as well as maximize the return on investment in drug research and development.

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499

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118274393

ISBN 13

9781118274392

The Leasing of Guantanamo Bay

By: Michael J. Strauss

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The Leasing of Guantanamo Bay

By: Michael J. Strauss

Post-2002 events at the U.S. naval facility at Guantanamo Bay have generated a spate of books on its use as a detention center in the U.S. fight against terrorism. Yet the crucial enabling factor-the lease that gave the U.S. control over the territory in Cuba-has till now escaped any but cursory consideration. The Leasing of Guantanamo Bay explains just how Guantanamo Bay came to be a leased territory where the U.S. has no sovereignty and Cuba has no jurisdiction. This is the first definitive account of the details and workings of the unusual and problematic state-to-state leasing arrangement that is the essential but murky foundation for all the ongoing controversies about Guantanamo Bay's role in U.S. anti-terrorism efforts, charges of U.S. human rights violations, and U.S.-Cuban relations. The Leasing of Guantanamo Bay provides an overview of territorial leasing between states and shows how it challenges, compromises, and complicates established notions of sovereignty and jurisdiction. Strauss unfolds the history of the Guantanamo Bay, recounting how the U.S. has deviated widely from the original terms of the lease yet never been legally challenged by Cuba, owing to the strong state-weak state dynamics. The lease is a hodge-podge of three U.S.-Cuba agreements full of discrepancies and uncorrected errors. Cuba's failure to cash the annual rent checks of the U.S. has legal implications not only for the future of Guantanamo Bay but of the Westphalian system of states. Compiled for the first time in one place are the verbatim texts of all the key documents relevant to the Guantanamo Bay lease-including treaties and other agreements, a previously unpublished U.N. legal assessment, and once-classified government correspondence.

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432

Publisher

Bloomsbury Publishing USA

Published Date

ISBN 13

9798216110187

Root-Cause Regulation

Protecting Work and Workers in the Twenty-First Century

By: Michael J. Piore,Andrew Schrank

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Root-Cause Regulation

Protecting Work and Workers in the Twenty-First Century

By: Michael J. Piore,Andrew Schrank

Work is now more deadly than war, killing approximately 2.3 million people a year worldwide. The United States, with its complex regulatory system, has one of the highest rates of occupational fatality in the developed world, and deteriorating working conditions more generally. Why, after a century of reform, are U.S. workers growing less safe and secure? Comparing U.S. regulatory practices to their European and Latin American counterparts, Root-Cause Regulation provides insight into the causes of this downward trend and ways to reverse it, offering lessons for rich and poor countries alike. The United States assigns responsibility for wages and hours, collective bargaining, occupational safety, and the like to various regulatory agencies. In France, Spain, and their former colonies, a single agency regulates all firms. Drawing on history, sociology, and economics, Michael Piore and Andrew Schrank examine why these systems developed differently and how they have adapted to changing conditions over time. The U.S. model was designed for the inspection of mass production enterprises by inflexible specialists and is ill-suited to the decentralized and destabilized employment of today. In the Franco-Iberian system, by contrast, the holistic perspective of multitasking generalists illuminates the root causes of noncompliance—which often lie in outdated techniques and technologies—and offers flexibility to tailor enforcement to different firms and market conditions. The organization of regulatory agencies thus represents a powerful tool. Getting it right, the authors argue, makes regulation not the job-killer of neoliberal theory but a generative force for both workers and employers.

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145

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Harvard University Press

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ISBN 10

0674986261

ISBN 13

9780674986268

The Chronicle of Achren 'Werwulf'

By: Michael J. Dennis

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The Chronicle of Achren 'Werwulf'

By: Michael J. Dennis

In the year 674, Ecgberht the Cyning and his entire giseth were slaughtered in the Anderedsweald. Their defeat sent shock waves throughout Cant.In Thanatus, Almund, Smith and the surviving men are struggling with the trauma of their battle with the Draugr. An experience that changed each of them forever. With a handful of warriors, Almund and Smith enter the forest to hunt down the truth behind the horrors he suspects deep within the Anderedsweald.

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132

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Michael J Dennis

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ISBN 10

1386746622

ISBN 13

9781386746621

The Chronicle of Achren 'Thanatus'

By: Michael J. Dennis

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The Chronicle of Achren 'Thanatus'

By: Michael J. Dennis

When night took hold would he stand in awe at those bodies forever beyond his touch? The trunk was far wider than he was tall, black and shining, gnarled, at first glance it reminded him of an ancient yew with many trunks intertwined as one, like wide ropes, knots and boles, a parody of a tree with no leaves or needles but an array of small bones, none of its branches swayed in the breeze. It stood brooding, motionless like no other tree he had ever seen. Its trunk formed of faces screaming to be free, arms and legs entwined with bodies. Locked together for eternity, its main branches composed of long bones fused as one, branching off into smaller versions of themselves a grotesque mockery of natural trees, ending in bud-like structures of knuckles, small bones and teeth looking much like fruit and flowers. Prydain stood eighty feet tall, it's all-encompassing branches appeared just as wide casting a bone-chilling shadow across the snow. Almund took a deep breath as he stepped back, slipping on a half-buried pile of bones that crunched beneath his boot. At first glance, Prydain looked as though conjured by some mad sorcerer, not grown from this good earth, but this was no trick, for all its deathly stillness he could feel its energy not formed by man but planted, its roots deep within the earth, abet many years ago in this rich soil for the veneration of Achren.

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453

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Michael J Dennis

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ISBN 10

1386862045

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9781386862048

The contribution of behavioural science to addressing the social and wider determinants of health

evidence review

By: Michael P KELLY,Ananya ARORA,Anjuli BANERJEE,Jack M BIRCH,Nnenna EKEKE,Isla KUHN,Carol BRAYNE,John FORD,Maria Raisa Jessica AQUINO,Beth CAPPER

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The contribution of behavioural science to addressing the social and wider determinants of health

evidence review

By: Michael P KELLY,Ananya ARORA,Anjuli BANERJEE,Jack M BIRCH,Nnenna EKEKE,Isla KUHN,Carol BRAYNE,John FORD,Maria Raisa Jessica AQUINO,Beth CAPPER

This report describes the differences and similarities between two approaches to health equity and inequalities. These approaches are individually oriented behaviour change and the social or wider determinants of health. The report is based on a review of reviews of the behavioural intervention and wider determinants literatures, and a narrative review of other relevant materials. The report makes the case for the scientific consilience between the differing approaches. This report is part of a suite of publications and tools designed to support Member States and public health practitioners to use behavioural science in their work.

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World Health Organization

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ISBN 10

9240072470

ISBN 13

9789240072473

How Not to Age

The Scientific Approach to Getting Healthier as You Get Older

By: Michael Greger, M.D., FACLM

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How Not to Age

The Scientific Approach to Getting Healthier as You Get Older

By: Michael Greger, M.D., FACLM

Instant New York Times Bestseller Uncover the evidence-based science to slowing the effects of aging, from the New York Times bestselling author of the How Not to Die series When Dr. Michael Greger, founder of NutritionFacts.org, dove into the top peer-reviewed anti-aging medical research, he realized that diet could regulate every one of the most promising strategies for combating the effects of aging. We don’t need Big Pharma to keep us feeling young—we already have the tools. In How Not to Age, the internationally renowned physician and nutritionist breaks down the science of aging and chronic illness and explains how to help avoid the diseases most commonly encountered in our journeys through life. Physicians have long treated aging as a malady, but getting older does not have to mean getting sicker. There are eleven pathways for aging in our bodies’ cells and we can disrupt each of them. Processes like autophagy, the upcycling of unusable junk, can be boosted with spermidine, a compound found in tempeh, mushrooms, and wheat germ. Senescent “zombie” cells that spew inflammation and are linked to many age-related diseases may be cleared in part with quercetin-rich foods like onions, apples, and kale. And we can combat effects of aging without breaking the bank. Why spend a small fortune on vitamin C and nicotinamide facial serums when you can make your own for up to 2,000 times cheaper? Inspired by the dietary and lifestyle patterns of centenarians and residents of “blue zone” regions where people live the longest, Dr. Greger presents simple, accessible, and evidence-based methods to preserve the body functions that keep you feeling youthful, both physically and mentally. Brimming with expertise and actionable takeaways, How Not to Age lays out practical strategies for achieving ultimate longevity.

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860

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Flatiron Books

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ISBN 10

1250796326

ISBN 13

9781250796325

Cardiology E-Book

By: Michael H. Crawford,John P. DiMarco,Walter J. Paulus

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Cardiology E-Book

By: Michael H. Crawford,John P. DiMarco,Walter J. Paulus

With your heavy case load, you can't afford to waste time searching for answers. Cardiology, 3rd Edition, by Drs. Crawford, DiMarco, and Paulus, offers you just the practical, problem-based guidance you need to quickly overcome any clinical challenge. 8 color-coded sections cover the 8 major clinical syndromes of cardiovascular disease—each section a virtual "mini textbook" on its topic! 40 new chapters keep you up to date with the latest advances in the field, while more than 2,000 lavish, high-quality illustrations, color photographs, tables, and ECGs capture clinical manifestations as they present in practice. It’s current, actionable information that you can put to work immediately for your patients! Offers a problem-based approach that integrates basic science, diagnostic investigations, and therapeutic management in one place for each cardiovascular disease so you can quickly find all of the actionable knowledge you need without flipping from one section to another. Features introductory bulleted highlights in each chapter that present the most pertinent information at a glance. Presents abundant algorithms to expedite clinical decision making. Includes more than 2,000 lavish, high-quality illustrations, color photographs, tables, and ECGs that capture clinical manifestations as they present in practice, and promote readability and retention. Includes 40 new chapters including Inherited Arrhythmia Syndromes, Implantable Cardioverter-Defibrillators and Cardiac Resynchronization Therapy in CHD, Management of the Cyanotic Patient with CHD, Special Problems for the Cardiology Consultant Dealing with Bariatric/Gastric Bypass — and many more — that equip you with all of the latest knowledge. Presents "Special Problem" sections—many new to this edition—that provide practical advice on problems that can be difficult to treat.

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2214

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Elsevier Health Sciences

Published Date

ISBN 10

0723436444

ISBN 13

9780723436447

The Cognitive Neurosciences

By: Michael S. Gazzaniga

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The Cognitive Neurosciences

By: Michael S. Gazzaniga

The third edition of a work that defines the field of cognitive neuroscience, with extensive new material including new chapters and new contributors.

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1486

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MIT Press

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ISBN 10

0262072548

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9780262072540

Kucers' The Use of Antibiotics Sixth Edition

A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs

By: M Lindsay Grayson,Suzanne M Crowe,James S McCarthy,John Mills,Johan W Mouton,S Ragnar Norrby,David L Paterson,Michael A Pfaller

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Kucers' The Use of Antibiotics Sixth Edition

A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs

By: M Lindsay Grayson,Suzanne M Crowe,James S McCarthy,John Mills,Johan W Mouton,S Ragnar Norrby,David L Paterson,Michael A Pfaller

I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics

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3211

Publisher

CRC Press

Published Date

ISBN 10

1444147528

ISBN 13

9781444147520

Book's by Michael J. Dennis

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